Interactions between Silica Particles in the Presence of Multivalent Coions

Forces between charged silica particles in solutions of multivalent coions are measured with colloidal probe technique based on atomic force microscopy. The concentration of 1:z electrolytes is systematically varied to understand the behavior of electrostatic interactions and double-layer properties in these systems. Although the coions are multivalent the Derjaguin, Landau, Verwey, and Overbeek (DLVO) theory perfectly describes the measured force profiles. The diffuse-layer potentials and regulation properties are extracted from the forces profiles by using the DLVO theory. The dependencies of the diffuse-layer potential and regulation parameter shift to lower concentration with increasing coion valence when plotted as a function of concentration of 1:z salt. Interestingly, these profiles collapse to a master curve if plotted as a function of monovalent counterion concentration

A Consumer-Centric Open Innovation Framework for Food and Packaging Manufacturing

This article has been archived following written permission from IGI Global.Closed innovation approaches have been employed for many years in the food industry. But, this sector recently perceives its end-user to be wary of radically new products and changes in consumption patterns. However, new product development involves not only the product itself but also the entire manufacturing and distribution network. In this paper, we present a new ICT based framework that embraces open innovation to place customers in the product development loop but at the same time assesses and eventually coordinates the entire manufacturing and supply chain. The aim is to design new food products that consumers will buy and at the same time ensure that these products will reach the consumer in time and at adequate quantity. On the product development side, our framework enables new food products that offer an integrated sensory experience of food and packaging, which encompass customization, healthy eating, and sustainability

Living with the user: Design drama for dementia care through responsive scripted experiences in the home

Participation in forms of drama and narrative can provoke empathy and creativity in user-centred design processes. In this paper, we expand upon existing methods to explore the potential for responsive scripted experiences that are delivered through the combination of sensors and output devices placed in a home. The approach is being developed in the context of Dementia care, where the capacity for rich user participation in design activities is limited. In this case, a system can act as a proxy for a person with Dementia, allowing designers to gain experiences and insight as to what it is like to provide care for, and live with, this person. We describe the rationale behind the approach, a prototype system architecture, and our current work to explore the creation of scripted experiences for design, played out though UbiComp technologies.This research is funded by the Arts and Humanities Research Council UK, (AH/K00266X/1) and Horizon Digital Economy Research (RCUK grant EP/G065802/1)

Using cultural probes to inform the design of assistive technologies

This paper discusses the practical implications of applying cultural probes to drive the design of assistive technologies. Specifically we describe a study in which a probe was deployed with home-based carers of people with dementia in order to capture critical data and gain insights of integrating the technologies into this sensitive and socially complex design space. To represent and utilise the insights gained from the cultural probes, we created narratives based on the probe data to enhance the design of assistive technologies.This work was supported by the Arts and Humanities Research Council (AH/K00266X/1) and RCUK through the Horizon Digital Economy Research grant (EP/G065802/1)

Investigating nuanced sensory experiences in textiles selection

In this study, research tools are used to investigate designers' textile selection activities and uncover the sensorial experiences that underpin those activities. Such tools were purposely introduced to disrupt the way designers generally interact with textiles and generate conversations around it. The study was conducted in a textile fair during two consecutive years with an expert audience who were in the mind-set of sourcing. This study resulted in four main themes that reveal the importance of the multisensory experience to textile selection, and the complexity of remembering and communicating such experiences in the design process, given how tacit such experiences are

A material flow analysis of the UK clothing economy

Historically, clothing accounted for a significant proportion of annual income for most UK citizens, so items were carefully preserved and often passed down through generations. In the 21st century, however, just 40 min of work at minimum wage is sufficient to purchase a dress, shirt, or pair of trousers that may be discarded after a handful of uses. UK per-capita clothing consumption is 2–3 times the global average, reliant on international supply chains associated with many environmental and social issues. Steering the clothing system towards ecological sustainability requires wide-ranging strategies, but the lack of data on flows of clothing makes it difficult to quantify the impacts of current production and consumption, let alone design and evaluate sustainability interventions. Here we use material flow analysis to track clothing flows through the UK economy as a prelude to considering embodied carbon and changes in economic value across the system. Our results show the system is characterised by relatively high rates of reuse but very low rates of recycling. More clothing is destroyed (via landfill and incineration) than is reused and recycled. Consequently, reducing consumption of new clothing by just ∼4% would be as effective for reducing waste as doubling current recycling activity. The UK also imports eight times more clothing than it produces, but offshores over half of the associated textile waste. In our carbon analysis, uncertainty is the key theme – estimates put the cradle-to-consumer emissions associated with 2018 UK clothing consumption anywhere from 9 Mt.CO₂e to over 30 Mt.CO₂e. Our economic analysis shows substantial, but unsurprising losses in economic value of clothing as it flows through the economy, with some unexpected nuances. Improving the accuracy of current flow and impact data is critical for understanding how the clothing system can be most effectively moved towards circularity

Radically Relational: Using Textiles As A Platform To Develop Methods For Embodied Design Processes

This position paper builds on textiles as a metaphor to explore the experiential knowledge observed through embodied design processes. In order to build understanding, we have tailored our tools and methods to support our explorations so far. As literature shows articulating our sensory experiences with materials is a challenging task. In order to support our investigations, in this paper we present a reflection on our diverse approaches to introduce tools that support us in interrogating how designers relate with materials, particularly textiles, and use their sensorial body to experience them during the creative process. We build on our previous research that identified relevant embodied process to textile selection, and reflect on how we have explored how sensing technology can augment and empower each of these phases, to support the design process. We conclude by discussing the learning outcomes from introducing such tools, in order to reflect on the future of our research

The seasonal evolution of subglacial drainage pathways beneath a soft-bedded glacier

Subglacial hydrology is a key element in glacier response to climate change, but investigations of this environment are logistically difficult. Most models are based on summer data from glaciers resting on rigid bedrocks. However a significant number of glaciers rest on soft (unconsolidated sedimentary) beds. Here we present a unique multi-year instrumented record of the development of seasonal subglacial behavior associated with an Icelandic temperate glacier resting on a deformable sediment layer. We observe a distinct annual pattern in the subglacial hydrology based on self-organizing anastomosing braided channels. Water is stored within the subglacial system itself (till, braided system and ‘ponds’), allowing the rapid access of water to enable glacier speed-up events to occur throughout the year, particularly in winter.publishedVersio

Spheres of Practice for the Co-design of Wearables

As expectations within the area of smart textiles increasingly become informed and driven by technological developments, the disciplinary boundaries and relationship between user and technological innovation will unavoidably transform. The authors venture that new paradigms of collaborative practice will inevitably develop between design and science, to more fully realize both the opportunities and contexts that wearable textiles offer. Drawing on previous work by the authors namely Molecular Imprinted Textiles (MIT - 2009/10), Future Textile Visions (FTV - 2010/11), Design Specks: Connecting People with Speckled Computing (2012/13), Second Skin (2013/14), and The S*** Word: Designing the Empathic Underwardrobe (2014), a model is proposed to more clearly understand and navigate between design, technology and application, and more importantly, between our cultural understanding of the user and the wearer. This paper reflects on a series of projects that inform a methodological approach: a process of asking questions; developing scenarios; exploring materials and making; generating concepts and building prototypes. Each project involved collaborations between design, academics, users and industry, and a form of co-design, where knowledge exchange was central, design was the intermediary, and the goal was to understand the drivers and the stakeholders. Simultaneously, this research sought to better understand and communicate the development of more empathic textile and fashion artifacts, and solutions. Co-design in this context is seen as a core approach to shifting the balance from technology as merely adjunct, or as a hook for marketers and users, to a more informed and harmonised position, where technology sits proximally and comfortably. The notion of interdisciplinary understanding, which tracks across domains of product, fashion and textiles, presents an approach where the application is still emerging. Through analysis of this progressive series of projects, the authors suggest that there is an opportunity to explore the inherent connectedness that textiles might offer for the integration and embedding of technology within material as a means to embrace these affordance opportunities. Central to this notion is the realisation of opportunities arising from dialogue and collaborative making (i.e. co-design), and for exploring the transformative notions of the user and the wearer. This paper led the authors to pose a set of questions that align to a four stage design process: Research, Define, Develop, Reflect, to frame findings and insights, and to outline the potential for future opportunities of working with technology to achieve the making and wearing of desirable materializations on the body

Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset

<p>Abstract</p> <p>Background</p> <p>Though rooted in genomic expression studies, pathway analysis for genome-wide association studies (GWAS) has gained increasing popularity, since it has the potential to discover hidden disease pathogenic mechanisms by combining statistical methods with biological knowledge. Generally, algorithms or programs proposed recently can be categorized by different types of input data, null hypothesis or counts of analysis stages. Due to complexity caused by SNP, gene and pathway relationships, re-sampling strategies like permutation are always utilized to derive an empirical distribution for test statistics for evaluating the significance of candidate pathways. However, evaluation of these algorithms on real GWAS datasets and real biological pathway databases needs to be addressed before we apply them widely with confidence.</p> <p>Findings</p> <p>Two algorithms which use summary statistics from GWAS as input were implemented in KGG, a novel and user-friendly software tool for GWAS pathway analysis. Comparisons of these two algorithms as well as the other five selected algorithms were conducted by analyzing the WTCCC Crohn's Disease dataset utilizing the MsigDB canonical pathways. As a result of using permutation to obtain empirical p-value, most of these methods could control Type I error rate well, although some are conservative. However, the methods varied greatly in terms of power and running time, with the PLINK truncated set-based test being the most powerful and KGG being the fastest.</p> <p>Conclusions</p> <p>Raw data-based algorithms, such as those implemented in PLINK, are preferable for GWAS pathway analysis as long as computational capacity is available. It may be worthwhile to apply two or more pathway analysis algorithms on the same GWAS dataset, since the methods differ greatly in their outputs and might provide complementary findings for the studied complex disease.</p