A cryopump for cooling objects at a distance

Design and construction of cryopump is reported that feeds from primary source to cool component up to 30 ft from source. Liquid oxygen or nitrogen is gravity fed through loop system to copper fibers enclosing component at room temperature where fluid boils, cools object, vaporizes and recycles through tubing loop

Relating the Time Complexity of Optimization Problems in Light of the Exponential-Time Hypothesis

Obtaining lower bounds for NP-hard problems has for a long time been an active area of research. Recent algebraic techniques introduced by Jonsson et al. (SODA 2013) show that the time complexity of the parameterized SAT($\cdot$) problem correlates to the lattice of strong partial clones. With this ordering they isolated a relation $R$ such that SAT($R$) can be solved at least as fast as any other NP-hard SAT($\cdot$) problem. In this paper we extend this method and show that such languages also exist for the max ones problem (MaxOnes($\Gamma$)) and the Boolean valued constraint satisfaction problem over finite-valued constraint languages (VCSP($\Delta$)). With the help of these languages we relate MaxOnes and VCSP to the exponential time hypothesis in several different ways.Comment: This is an extended version of Relating the Time Complexity of Optimization Problems in Light of the Exponential-Time Hypothesis, appearing in Proceedings of the 39th International Symposium on Mathematical Foundations of Computer Science MFCS 2014 Budapest, August 25-29, 201

Single session imaging of cerebellum at 7 tesla: Obtaining structure and function of multiple motor subsystems in individual subjects

The recent increase in the use of high field MR systems is accompanied by a demand for acquisition techniques and coil systems that can take advantage of increased power and accuracy without being susceptible to increased noise. Physical location and anatomical complexity of targeted regions must be considered when attempting to image deeper structures with small nuclei and/or complex cytoarchitechtonics (i.e. small microvasculature and deep nuclei), such as the brainstem and the cerebellum (Cb). Once these obstacles are overcome, the concomitant increase in signal strength at higher field strength should allow for faster acquisition of MR images. Here we show that it is technically feasible to quickly and accurately detect blood oxygen level dependent (BOLD) signal changes and obtain anatomical images of Cb at high spatial resolutions in individual subjects at 7 Tesla in a single one-hour session. Images were obtained using two high-density multi-element surface coils (32 channels in total) placed beneath the head at the level of Cb, two channel transmission, and three-dimensional sensitivity encoded (3D, SENSE) acquisitions to investigate sensorimotor activations in Cb. Two classic sensorimotor tasks were used to detect Cb activations. BOLD signal changes during motor activity resulted in concentrated clusters of activity within the Cb lobules associated with each task, observed consistently and independently in each subject: Oculomotor vermis (VI/VII) and CrusI/II for pro- and anti-saccades; ipsilateral hemispheres IV-VI for finger tapping; and topographical separation of eye- and hand- activations in hemispheres VI and VIIb/VIII. Though fast temporal resolution was not attempted here, these functional patches of highly specific BOLD signal changes may reflect small-scale shunting of blood in the microvasculature of Cb. The observed improvements in acquisition time and signal detection are ideal for individualized investigations such as differentiation of functional zones prior to surgery. Copyright

Moral Hypocrisy and Acting for Reasons: How Moralizing Can Invite Self-Deception

According to some, contemporary social psychology is aptly described as a study in moral hypocrisy. In this paper we argue that this is unfortunate when understood as establishing that we only care about appearing to act morally, not about true moral action. A philosophically more interesting interpretation of the “moral hypocrisy”-findings understands it to establish that we care so much about morality that it might lead to (1) self-deception about the moral nature of our motives and/or (2) misperceptions regarding what we should or should not do in everyday or experimental situations. In this paper we argue for this claim by elaborating on a fascinating series of experiments by Daniel Batson and his colleagues who have consistently contributed to the moral hypocrisy findings since the late nineties, and showing in what way they contribute to a better understanding of moral agency, rather than undermine the idea that we are moral agents

\u201cGive, but Give until It Hurts\u201d: The Modulatory Role of Trait Emotional Intelligence on the Motivation to Help

Two studies investigated the effect of trait Emotional Intelligence (trait EI) on people\u2019s moti- vation to help. In Study 1, we developed a new computer-based paradigm that tested partic- ipants\u2019 motivation to help by measuring their performance on a task in which they could gain a hypothetical amount of money to help children in need. Crucially, we manipulated partici- pants\u2019 perceived efficacy by informing them that they had been either able to save the chil- dren (positive feedback) or unable to save the children (negative feedback). We measured trait EI using the Trait Emotional Intelligence Questionnaire\u2013Short Form (TEIQue-SF) and assessed participants\u2019 affective reactions during the experiment using the PANAS-X. Results showed that high and low trait EI participants performed differently after the presen- tation of feedback on their ineffectiveness in helping others in need. Both groups showed increasing negative affective states during the experiment when the feedback was negative; however, high trait EI participants better managed their affective reactions, modulating the impact of their emotions on performance and maintaining a high level of motivation to help. In Study 2, we used a similar computerized task and tested a control situation to explore the effect of trait EI on participants\u2019 behavior when facing failure or success in a scenario unre- lated to helping others in need. No effect of feedback emerged on participants\u2019 emotional states in the second study. Taken together our results show that trait EI influences the impact of success and failure on behavior only in affect-rich situation like those in which people are asked to help others in need

Why are the oldest old less generous? Explanations for the unexpected age-related drop in charitable giving

ABSTRACT Previous research has demonstrated that the generally positive relationship between age and the presence of charitable giving becomes negative at the oldest ages. We investigate potential causes of this drop in charitable giving among the oldest old including changes in health, cognition, egocentric networks, religious attendance, and substitution of charitable bequest planning. A longitudinal analysis of data from the United States Health and Retirement Survey indicates that the drop in charitable giving is mediated largely by changes in the frequency of church attendance, with only modest influences from changes in health and cognition

What went wrong? The flawed concept of cerebrospinal venous insufficiency

In 2006, Zamboni reintroduced the concept that chronic impaired venous outflow of the central nervous system is associated with multiple sclerosis (MS), coining the term of chronic cerebrospinal venous insufficiency ('CCSVI'). The diagnosis of 'CCSVI' is based on sonographic criteria, which he found exclusively fulfilled in MS. The concept proposes that chronic venous outflow failure is associated with venous reflux and congestion and leads to iron deposition, thereby inducing neuroinflammation and degeneration. The revival of this concept has generated major interest in media and patient groups, mainly driven by the hope that endovascular treatment of 'CCSVI' could alleviate MS. Many investigators tried to replicate Zamboni's results with duplex sonography, magnetic resonance imaging, and catheter angiography. The data obtained here do generally not support the 'CCSVI' concept. Moreover, there are no methodologically adequate studies to prove or disprove beneficial effects of endovascular treatment in MS. This review not only gives a comprehensive overview of the methodological flaws and pathophysiologic implausibility of the 'CCSVI' concept, but also summarizes the multimodality diagnostic validation studies and open-label trials of endovascular treatment. In our view, there is currently no basis to diagnose or treat 'CCSVI' in the care of MS patients, outside of the setting of scientific research