116 research outputs found
Does buyer-seller similarity affect buyer satisfaction with the seller firm?
With the increased reliance on diverse markets in multi-cultural contexts, the role that similarity can play in the relationship between a salesperson and a buyer is receiving increased attention. Similarity is regarded as the cornerstone of positive communications, and salespeople rely on the trust that can be created by this recognition of likeness. However, there are different types of similarity, and not all have an equal bearing on the salesperson-buyer relationship. In this study, we examine similarity in appearance, similarity in lifestyle, and similarity in status. Most studies go no further than examining the effect of similarity on a buyer’s satisfaction with a salesperson, and to date there appear to be few studies relating to the effect of similarity on satisfaction with a firm. This study examines the effect of similarity on a buyer’s sense of satisfaction with a firm represented by a salesperson in the banking context. The results of the study show that appearance similarity and status similarity have a significant effect on the salesperson-buyer relationship, whereas lifestyle similarity has no effect. The buyer’s satisfaction with a salesperson is found to mediate the relationship between similarity in appearance and the buyer’s satisfaction with a firm. In this paper, we discuss these findings and look at their implications for both research and practice. Findings of the study are particularly important because of New Zealand’s increasing interaction with Asia and its people, which has transformed New Zealand to become a multi-cultural and multi-ethnic country
Challenges and perspectives on innovative technologies for biofuel production and sustainable environmental management
Specifically, human activities, such as those in industry and transportation, have resulted in an increase in the demand for fossil fuels, resulting in severe environmental problems.Throughout this article, we discuss the potential and challenges associated with the production of biofuels from a variety of feedstocks and advances in processing technologies utilizing a range of feedstocks. Based on the conclusion of the study, we conclude that bioenergy is a green alternative to be used for diverse energy needs, once the appropriate conversion processes are applied. The production of biofuels and their use in industries and transportation have significantly reduced the use of fossil fuels. The literature review concluded that producing biofuels from energy crops and microalgae was the most efficient and attractive method. The purpose of this review is to explain all aspects of biofuels and their sustainability criteria. With a particular focus on the role of nanotechnology in biofuel production, this article discusses the most recent advances in biofuel production. A number of emerging techniques have been investigated for improving process quality, including integrated techniques, less energy-intensive distillation strategies, and the use of microorganisms in engineering. A challenging aspect of biofuel production on a large scale remains; therefore, a novel technology must be developed in order to enhance biofuel production in order to meet the challenges and meet future energy needs
Incorporating prediction into adaptive streaming algorithms: a QoE perspective
Streaming over the wireless channel is challenging due to rapid fluctuations in available throughput. Encouraged by recent advances in cellular throughput prediction based on radio link metrics, we examine the impact on Quality of Experience (QoE) when using prediction within existing algorithms based on the DASH standard. By design, DASH algorithms estimate available throughput at the application level from chunk rates and then apply some averaging function. We investigate alternatives for modifying these algorithms, by providing the algorithms direct predictions in place of estimates or feeding predictions in place of measurement samples. In addition, we explore different prediction horizons going from one to three chunk durations. Furthermore, we induce different levels of error to ideal prediction values to analyse deterioration in user QoE as a function of average error. We find that by applying accurate prediction to three algorithms, user QoE can improve up to 55% depending on the algorithm in use. Furthermore having longer horizon positively affects QoE metrics. Accurate predictions have the most significant impact on stall performance by completely eliminating them. Prediction also improves switching behaviour significantly and longer prediction horizons enable a client to promptly reduce quality and avoid stalls when the throughput drops for a relatively long time that can deplete the buffer. For all algorithms, a 3-chunk horizon strikes the best balance between different QoE metrics and, as a result, achieving highest user QoE. While error-induced predictions significantly lower user QoE in certain situations, on average, they provide 15% improvement over DASH algorithms without any prediction
Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial
Introduction:
We assessed whether modest systemic cooling started within 6 hours of symptom onset improves functional outcome at three months in awake patients with acute ischaemic stroke.
Patients and methods:
In this European randomised open-label clinical trial with blinded outcome assessment, adult patients with acute ischaemic stroke were randomised to cooling to a target body temperature of 34.0–35.0°C, started within 6 h after stroke onset and maintained for 12 or 24 h , versus standard treatment. The primary outcome was the score on the modified Rankin Scale at 91 days, as analysed with ordinal logistic regression.
Results:
The trial was stopped after inclusion of 98 of the originally intended 1500 patients because of slow recruitment and cessation of funding. Forty-nine patients were randomised to hypothermia versus 49 to standard treatment. Four patients were lost to follow-up. Of patients randomised to hypothermia, 15 (31%) achieved the predefined cooling targets. The primary outcome did not differ between the groups (odds ratio for good outcome, 1.01; 95% confidence interval, 0.48–2.13; p = 0.97). The number of patients with one or more serious adverse events did not differ between groups (relative risk, 1.22; 95% confidence interval, 0.65–1.94; p = 0.52).
Discussion:
In this trial, cooling to a target of 34.0–35.0°C and maintaining this for 12 or 24 h was not feasible in the majority of patients. The final sample was underpowered to detect clinically relevant differences in outcomes.
Conclusion:
Before new trials are launched, the feasibility of cooling needs to be improved
Restraint and Social Isolation Stressors Differentially Regulate Adaptive Immunity and Tumor Angiogenesis in a Breast Cancer Mouse Model
The ability of stress to induce immune suppression is widely recognized, but the mechanisms underlying the effects of stress on the adaptive immune system during tumor progression are not completely understood. To study the effect of stress on the immune system in vivo, we used a preclinical immunocompetent mouse model bearing 4T1 mammary adenocarcinoma cells. Mice were randomized into 4 groups, including social isolation (SI), acute restraint stress (aRRS), chronic restraint stress (cRRS), or no stress (NS). We found that SI significantly decreased the number of tumor-bearing mice still alive at the end of protocol (28 days), compared to NS mice. Although we did not detect significant changes in primary tumor volume, we observed a significant increase in the endothelial marker CD31 in primary tumors of SI mice and in lung metastases in SI and RRS mice. Survival decline in SI mice was associated with significant decreases in splenic CD8 cells and in activated T cells. From a mechanistic standpoint, RRS increased expression of FOXP3, CXCL-10, and granzyme B in mouse tumors, and the effects were reversed by propranolol. Our data demonstrate that various forms of stress differentially impact adaptive immunity and tumor angiogenesis, and negatively impact survival.</jats:p
Therapeutic hypothermia for acute ischaemic stroke. Results of a European multicentre, randomised, phase III clinical trial
Introduction: We assessed whether modest systemic cooling started within 6 hours of symptom onset improves functional outcome at three months in awake patients with acute ischaemic stroke. Patients and methods: In this European randomised open-label clinical trial with blinded outcome assessment, adult patients with acute ischaemic stroke were randomised to cooling to a target body temperature of 34.0–35.0°C, started within 6 h after stroke onset and maintained for 12 or 24 h, versus standard treatment. The primary outcome was the score on the modified Rankin Scale at 91 days, as analysed with ordinal logistic regression. Results: The trial was stopped after inclusion of 98 of the originally intended 1500 patients because of slow recruitment and cessation of funding. Forty-nine patients were randomised to hypothermia versus 49 to standard treatment. Four patients were lost to follow-up. Of patients randomised to hypothermia, 15 (31%) achieved the predefined cooling targets. The primary outcome did not differ between the groups (odds ratio for good outcome, 1.01; 95% confidence interval, 0.48–2.13; p = 0.97). The number of patients with one or more serious adverse events did not differ between groups (relative risk, 1.22; 95% confidence interval, 0.65–1.94; p = 0.52). Discussion: In this trial, cooling to a target of 34.0–35.0°C and maintaining this for 12 or 24 h was not feasible in the majority of patients. The final sample was underpowered to detect clinically relevant differences in outcomes. Conclusion: Before new trials are launched, the feasibility of cooling needs to be improved
Prenatal Stress and Balance of the Child's Cardiac Autonomic Nervous System at Age 5-6 Years
Objective: Autonomic nervous system (ANS) misbalance is a potential causal factor in the development of cardiovascular disease. The ANS may be programmed during pregnancy due to various maternal factors. Our aim is to study maternal prenatal psychosocial stress as a potential disruptor of cardiac ANS balance in the child. Methods: Mothers from a prospective birth cohort (ABCD study) filled out a questionnaire at gestational week 16 [IQR 12– 20], that included validated instruments for state anxiety, depressive symptoms, pregnancy-related anxiety, parenting daily hassles and job strain. A cumulative stress score was also calculated (based on 80 th percentiles). Indicators of cardiac ANS in the offspring at age 5–6 years are: pre-ejection period (PEP), heart rate (HR), respiratory sinus arrhythmia (RSA) and cardiac autonomic balance (CAB), measured with electrocardiography and impedance cardiography in resting supine and sitting positions. Results: 2,624 mother-child pairs, only single births, were available for analysis. The stress scales were not significantly associated with HR, PEP, RSA and CAB (p0.07). Conclusion: Results did not support the hypothesis that prenatal maternal psychosocial stress deregulates cardiac AN
A global classroom? evaluating the effectiveness of global virtual collaboration as a teaching tool in management education
We evaluate the effectiveness of global virtual student collaboration projects in international management education.Over 6,000 students from nearly 80 universities in 43 countries worked in global virtual teams for 2 months as part of their international management courses.Multisource longitudinal data were collected, including student and instructor feedback, course evaluations, assessment of changes in knowledge, attitudes, and behaviors following the experiential project, and various indicators of
individual and team performance.Drawing on experiential learning, social learning, and
intergroup contact theories, the effectiveness of the experiential global virtual teambased
approach in international management education was evaluated at the levels of reactions, learning, attitudes, behaviors, and performance.The findings show positive outcomes at each level, but also reveal challenges and limitations of using global virtual team projects for learning and education. Implications for international management education and suggestions for future research are discussed
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