746 research outputs found
M2-M5 blackfold funnels
We analyze the basic M2-M5 intersection in the supergravity regime using the
blackfold approach. This approach allows us to recover the 1/4-BPS self-dual
string soliton solution of Howe, Lambert and West as a three-funnel solution of
an effective fivebrane worldvolume theory in a new regime, the regime of a
large number of M2 and M5 branes. In addition, it allows us to discuss finite
temperature effects for non-extremal self-dual string soliton solutions and
wormhole solutions interpolating between stacks of M5 and anti-M5 branes. The
purpose of this paper is to exhibit these solutions and their basic properties.Comment: 19 pages, 5 figures, harvmac; typo corrected in equation (3.19
Deformed Quantum Cohomology and (0,2) Mirror Symmetry
We compute instanton corrections to correlators in the genus-zero topological
subsector of a (0,2) supersymmetric gauged linear sigma model with target space
P1xP1, whose left-moving fermions couple to a deformation of the tangent
bundle. We then deduce the theory's chiral ring from these correlators, which
reduces in the limit of zero deformation to the (2,2) ring. Finally, we compare
our results with the computations carried out by Adams et al.[ABS04] and Katz
and Sharpe[KS06]. We find immediate agreement with the latter and an
interesting puzzle in completely matching the chiral ring of the former.Comment: AMSLatex, 30 pages, one eps figure. V4: typos corrected, final
version appearing in JHE
Constraints on Automorphic Forms of Higher Derivative Terms from Compactification
By dimensionally reducing the higher derivative corrections of
ten-dimensional IIB theory on a torus we deduce constraints on the E_{n+1}
automorphic forms that occur in d=10-n dimensions. In particular we argue that
these automorphic forms involve the representation of E_{n+1} with fundamental
weight \lambda^{n+1}, which is also the representation to which the string
charges in d dimensions belong. We also consider a similar calculation for the
reduction of higher derivative terms in eleven-dimensional M-theory.Comment: Minor corrections, to appear in JHE
Higher derivative type II string effective actions, automorphic forms and E11
By dimensionally reducing the ten-dimensional higher derivative type IIA
string theory effective action we place constraints on the automorphic forms
that appear in the effective action in lower dimensions. We propose a number of
properties of such automorphic forms and consider the prospects that E11 can
play a role in the formulation of the higher derivative string theory effective
action.Comment: 34 page
The Overall Coefficient of the Two-loop Superstring Amplitude Using Pure Spinors
Using the results recently obtained for computing integrals over
(non-minimal) pure spinor superspace, we compute the coefficient of the
massless two-loop four-point amplitude from first principles. Contrasting with
the mathematical difficulties in the RNS formalism where unknown normalizations
of chiral determinant formulae force the two-loop coefficient to be determined
only indirectly through factorization, the computation in the pure spinor
formalism can be smoothly carried out.Comment: 29 pages, harvmac TeX. v2: add reference
Gauge and Supersymmetric Invariance of a Boundary Bagger-Lambert-Gustavsson Theory
In this paper we will discuss the effect of a having a boundary on the
supersymmetric invariance and gauge invariance of the Bagger-Lambert-Gustavsson
(BLG) Theory. We will show that even though the supersymmetry and gauge
invariance of the original BLG theory is broken due to the presence of a
boundary, it restored by the addition of suitable boundary terms. In fact, to
achieve the gauge invariance of this theory, we will have to introduce new
boundary degrees of freedom. The boundary theory obeyed by these new boundary
degrees of freedom will be shown to be a generalization of the gauged
Wess-Zumino-Witten model, with the generators of the Lie algebra replaced by
the generators of the Lie 3-algebra. The gauge and supersymmetry variations of
the boundary theory will exactly cancel the boundary terms generated by the
gauge and supersymmetric variations of the bulk theory.Comment: 15 pages, 0 figures, accepted for publication in JHE
N=8 Superspace Constraints for Three-dimensional Gauge Theories
We present a systematic analysis of the N=8 superspace constraints in three
space-time dimensions. The general coupling between vector and scalar
supermultiplets is encoded in an SO(8) tensor W_{AB} which is a function of the
matter fields and subject to a set of algebraic and super-differential
relations. We show how the conformal BLG model as well as three-dimensional
super Yang-Mills theory provide solutions to these constraints and can both be
formulated in this universal framework.Comment: 34 + 10 pages; added references, minor correction
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Cost of care for cancer patients in England: evidence from population-based patient-level data
background: Health systems are facing the challenge of providing care to an increasing population of patients with cancer. However, evidence on costs is limited due to the lack of large longitudinal databases.
methods: We matched cost of care data to population-based, patient-level data on cancer patients in England. We conducted a retrospective cohort study including all patients age 18 and over with a diagnosis of colorectal (275 985 patients), breast (359 771), prostate (286 426) and lung cancer (283 940) in England between 2001 and 2010. Incidence costs, prevalence costs, and phase of care costs were estimated separately for patients age 18–64 and greater than or equal to65. Costs of care were compared by patients staging, before and after diagnosis, and with a comparison population without cancer.
results: Incidence costs in the first year of diagnosis are noticeably higher in patients age 18–64 than age greater than or equal to65 across all examined cancers. A lower stage diagnosis is associated with larger cost savings for colorectal and breast cancer in both age groups. The additional costs of care because of the main four cancers amounts to £1.5 billion in 2010, namely 3.0% of the total cost of hospital care.
conclusions: Population-based, patient-level data can be used to provide new evidence on the cost of cancer in England. Early diagnosis and cancer prevention have scope for achieving large cost savings for the health system
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