The Growth of Seaweed (Kappaphycus Alvarezii) Cultivated with Long Line and Off Bottom Method on Tita Banda Neira Maluku Coastal Area

This research aimed to know the growth rate of seaweed (Kappaphycus alvarezii) cultivated by using off bottom method and long line method in coastal waters Tita Dwiwarna Village Banda Central of Maluku. It is expected that this research will provide basic information in business of seaweed cultivation to be developed. The methods were off bottom method and long line method that consisted of 2 treatments and 3 replications. Material used was mostly a polyethylene rope as long as 10 meters with the diameter size 5 mm for a mine rope and 3 mm for a span rope. Initial weight of sea weeds which is tied to a span rope 100 gram. The growth data collection was taken simultaneously with water quality data every week. Data were analyzed by using Cohran test to see homogeneity. The homogeneity data were then analyzed by using t-test to see the different between two treatments. The result of the research has shown that seaweed growth was highest in off bottom methods which average weight on the seventh week reached 690 gram. While the growth with long line methods reached the average weight on the seventh week reached only 609.4 gram. Therefore, the best growth of the sea weed was represented by off bottom method

Safety of Annona Muricata Extract Supplementation for Colorectal Cancer Patients

Background: People have used Annona muricata leaves traditionally as tea drinks. Traditional use of A. muricata leaves is as an infusion which is closed to water extract. The potential health benefit of A. muricata tea leaves that is traditionally used for maintaining health which lately is being used by cancer patients. Therefore it is urgent to verify the safety of A. muricata leaves extract. Method: A randomized double blind placebo controlled trial was conducted on 30 colorectal cancer out patients who had undergone primary tumor resection. Twenty eight subjects completed the study, divided into two groups, namely ethanol-soluble fraction of A. muricata leaves water extract (ESFAM) (n = 14), and placebo (n = 14) for 8 weeks. Peripheral blood samples were withdrawn from subjects by venipuncture at baseline and at the end of the study period.Results: The effect on bone marrow can be considered to be safe. The measure in indices of organs function, i.e liver and kidney also showed similar results and within normal range after supplementation. The dose given to the subjects is safe and highly tolerable, as shown by very few (6.7%) of patients complained intolerable adverse effects. Conclusion: This study indicates the safety of ESFAM supplementation

Relationship of the Role of Counselor, Knowledge, Trust, Values, and Social Relationship in Contraception Acceptors’ Decision of Using Intrauterine Device (IUD): Hubungan Faktor Peran Konselor, Pengetahuan, Kepercayaan, Nilai, dan Kekerabatan terhadap Keputusan Akseptor KB untuk Menggunakan Kontrasepsi Intrauterine Device (IUD)

Abstract Objective: to assess the relationship of the role of counselor, knowledge, trust, values, and social relationship regarding acceptors’ decision in using intrauterine device at Dr. Mohammad Hoesin Hospital Palembang. Method: An observational analytical cross-sectional research carried out on June 2017 until September 2017 in the Department of Obstetrics and Gynecology Dr. Mohammad Hoesin General Hospital. 40 subjects were included. The frequency and distribution data were described in table form, bivariate analysis was performed to assess the relationship between independent and dependent variables statistically using Chi-square/Fisher Exact test. Multivariate analysis using logistic regression test was performed to assess which independent variable affects acceptors’ decision the most. Data analysis was performed using SPSS 18.0 version.  Results: There were no statistically differences in age, duration of marriage, parity, number of children born alive, abortion, education, and jobs between the two groups (p<0.05). There was statistically significant relationship between knowledge, social relationship, and the role of counselor with contraception acceptors’ decision (p<0.005), but there was no significant relationship between trust and values with contraception acceptors’ decision (p>0.05). Meanwhile, the logistic regression analysis showed that the role of counselor significantly affects contraception acceptors’ decision (PR=108.989, p value=0.002). Concluson: The role of counselor is a factor that affects contraception acceptors’ decision in using IUD. Keywords: IUD, role of counselor, social relationship, trust, values, knowledge   Abstrak Tujuan: untuk mengetahui hubungan faktor peran konselor, pengetahuan, kepercayaan, nilai, dan kekerabatan terhadap keputusan akseptor KB untuk menggunakan alat kontrasepsi IUD di Rumah Sakit Mohammad Hoesin Palembang. Metode: Penelitian analitik observasional rancangan cross sectional ini dilakukan di Departemen Obstetri dan Ginekologi Rumah Sakit Dr. Mohammad Hoesin/Fakultas Kedokteran Universitas Sriwijaya Palembang sejak bulan Juni sampai September 2017. Didapatkan sampel sebanyak 40 wanita melahirkan memenuhi kriteria inklusi. Frekuensi dan distribusi data dijelaskan dalam bentuk tabel, analisa bivariat untuk mengetahui ada tidaknya hubungan secara statistik antara variabel bebas dan dengan variabel terikat menggunakan uji Chi Square/Fisher Exact dan analisis multivariat untuk mengetahui variabel independen mana yang paling besar pengaruhnya terhadap keputusan akseptor KB untuk menggunakan alat kontrasepsi IUD menggunakan uji Regresi Logistik. Analisa data menggunakan SPSS versi 18.0. Hasil: Tidak terdapat perbedaan karakteristik pasien baik usia, lama pernikahan, paritas, jumlah anak hidup, abortus, pendidikan dan pekerjaan antara kedua kelompok (p<0,05). Terdapat hubungan yang signifikan antara pengetahuan, kekerabatan, dan peran konselor dengan keputusan akspetor KB IUD (p<0,05), namun tidak terdapat hubungan yang signifikan antara kepercayaan dan nilai dengan keputusan akspetor KB IUD (p  > 0,05).  Pada analisis regresi logistik didapatkan hasil peran konselor berpengaruh secara signifikan terhadap keputusan akseptor KB IUD (PR = 108,989, p value = 0,002). Keimpulan: Peran konselor merupakan faktor yang mempengaruhi keputusan akseptor KB untuk menggunakan alat kontrasepsi IUD. Kata Kunci: IUD, Peran Konselor, Kekerabatan, Kepercayaan Nilai, Pengetahuan

Left Atrial-Veno-Arterial Extracorporeal Membrane Oxygenation: Step-By-Step Procedure and Case Example

Veno-arterial extracorporeal membrane oxygenation is used in patients requiring biventricular support; however, its use increases the afterload. In patients with severe aortic insufficiency or severe left ventricular disfunction, it will increase left-side filling pressures, hence the need for left ventricle unloading with an additional mechanical circulatory support device. We present a case of a patient with cardiogenic shock and severe aortic insufficiency who underwent left atrial veno-arterial extracorporeal membrane oxygenation and provide a step-by-step explanation of the technique

Effects of low-intensity continuous ultrasound on hematological parameters of rats

Background: Low intensity ultrasound (US) has some well-known bio-effects which are of great importance to be considered. Objective: We conducted the present study to investigate the effects of low intensity continuous ultrasound on blood cells count in rat. Methods: Rats were anesthetized and blood samples were collected before US exposure. Then, they were exposed to US with nominal intensity of 0.2 W/cm2 at frequency of 3 MHz for a period of 10 minutes and this protocol was repeated for 7 days. Twenty four hours after the last US exposure, secondary blood samples were collected and the changes in blood parameters were evaluated. Results: Analysis revealed that platelets, hematocrit (HCT) and hemoglobin (HGB) were significantly different between experimental and sham groups but no difference between sham and control groups was observed. The results show that HCT and HGB of exposed rats were significantly reduced. Conclusion: This study shows that low intensity US may lead to side effects for hematological parameters such as reduction in the levels of HGB and HCT. © 2016 Shiraz University of Medical Sciences. All rights reserved

Safety, feasibility, and outcomes of transcaval access for the delivery of Impella microaxial-flow pump 5.0 in patients with acute heart failure

Background: Transcaval access (TCA) may enable fully percutaneous mechanical circulatory support (MCS) without the hazards of vascular complication in patients with heart failure that require left ventricular unloading. Purpose: To review the safety, feasibility, and outcomes of using TCA to deliver Impella 5.0 MCS in patients with ischemic and non-ischemic systolic acute heart failure. Methods: This single center retrospective study included all patients that underwent TCA placement of a 5.0 Impella from June 2015 to January 2021. Demographic, clinical and procedural variables, and in-hospital outcomes were collected. The procedure was performed by electrifying a caval guidewire and advancing it into a pre-positioned aortic snare. After exchanging for a rigid guidewire, a 22 or 24Fr sheath was delivered into the aorta and then the Impella 5.0 was placed in the left ventricle through TCA sheaths. Results: A total of 43 patients were included in the analysis. The average age was 56.9 years (interquartile range [IQR], 52-65.5), of which, 70%(n=30) were males. Fifteen patients had non-ischemic cardiomyopathy and 28 had ischemic cardiomyopathy. Baseline average left ventricular ejection fraction prior to implantation was 23.6% (IQR, 13.75-29.75). 86% of the patients were in category C-D of the SCAI classification schema for cardiogenic shock (CS), 39.5% required inotropes and 48.8% required pressors prior to the procedure; 54% had a prior MCS in place. Only 18.6% of the cases had prior CT imaging reviewed for planning. TCA was successful in all attempted patients and the MCS delivery was achieved in 100% of the cohort. The available hemodynamic parameters prior and after Impella 5.0 implantation via Table 1 TCA are summarized in table 1. From the total cohort, only 29 patients survived to explant device and TCA sheath. The explant was successful in all patients using nitinol occluders; two patients required a covered stent at the arteriotomy site due to right sided heart failure from residual fistula; no surgical repair was necessary. All residual fistulous tracks were graded as1 from Impella insertion/removal site was observed in 9.3%,which didn\u27t require further intervention. No vascular complication of the access site was observed with TCA. During hospitalization, 20.9% had VT/VF and 4.7% a PEA after implantation (all CS patients). 13.9% of the patients had AKI requiring hemodialysis and no stroke was observed in the entire group. The average length of stay for entire cohort was 16.3 days (IQR, 3.25-18.75). Conclusions: Transcaval access of 5.0 Impella is safe and feasible under expert hands for patients where more conventional MCS devices do not provide enough support or have inadequate peripheral arterial access

TCT-175 Safety and Complications Associated With the Use of Protamine in Percutaneous Coronary Intervention

Background: There is a paucity of data on the use of protamine after percutaneous coronary intervention (PCI). Methods: We conducted a retrospective analysis of 168 patients who underwent PCI from 2015 to 2021. All patients received protamine intra- or immediately after index PCI. We evaluated baseline characteristics, intraprocedural characteristics including heparin dosing and protamine dosing, and complications such as acute stent thrombosis (ST), dissection, perforation, and access-site bleeding. The primary outcome was the incidence of acute ST, subacute ST, and other thrombotic complications. Secondary outcomes included mortality within 24 hours and within 28 days of the index procedure. Results: One hundred sixty-eight patients were included. The mean age of patients was 72 ± 12.1 years, and 36% were women. The majority of patients received antiplatelet therapy prior to the index procedure (90%), and the average ejection fraction (EF) was 50% ± 14.3%. Of the 33 insulin-dependent patients (20%), only 1 (0.5%) used neutral protamine Hagedorn insulin. One hundred fifteen of the procedures (68%) were elective, and the average procedure time was 3 hours 21 minutes (SD 1 hour 43 minutes). Fifty-nine patients underwent rotational, orbital, or laser atherectomy (27, 23, and 9 patients, respectively). An average of 2.59 ± 1.38 stents were deployed, and intravascular ultrasound was used in 96 patients (57%). An average protamine dose of 32 mg was administered. Seventy-three patients (43%) had coronary perforations, and 19 (11%) had pericardial effusions requiring pericardiocentesis. Twenty-one patients (13%) had coronary dissections following PCI, and 6 (4%) had access-site bleeding requiring transfusion. Three patients (2%) underwent urgent cardiac surgery. Eight (5%) died within 24 hours of PCI, and 6 (3.5%) died within 28 days of PCI. Four patients (2%) had acute ST, no patients experienced subacute ST, and 1 patient (0.5%) developed arterial thrombosis (common femoral artery). Conclusions: Use protamine in PCI typically occurred because of intraprocedural complications. In our series, protamine was tolerated well in the majority of patients, but 3% of patients experienced coronary or arterial thrombosis, warranting caution when using protamine in these challenging scenarios. Categories: CORONARY: Stents: Drug-Elutin

Context-dependent combination of sensor information in Dempster–Shafer theory for BDI

© 2016, The Author(s). There has been much interest in the belief–desire–intention (BDI) agent-based model for developing scalable intelligent systems, e.g. using the AgentSpeak framework. However, reasoning from sensor information in these large-scale systems remains a significant challenge. For example, agents may be faced with information from heterogeneous sources which is uncertain and incomplete, while the sources themselves may be unreliable or conflicting. In order to derive meaningful conclusions, it is important that such information be correctly modelled and combined. In this paper, we choose to model uncertain sensor information in Dempster–Shafer (DS) theory. Unfortunately, as in other uncertainty theories, simple combination strategies in DS theory are often too restrictive (losing valuable information) or too permissive (resulting in ignorance). For this reason, we investigate how a context-dependent strategy originally defined for possibility theory can be adapted to DS theory. In particular, we use the notion of largely partially maximal consistent subsets (LPMCSes) to characterise the context for when to use Dempster’s original rule of combination and for when to resort to an alternative. To guide this process, we identify existing measures of similarity and conflict for finding LPMCSes along with quality of information heuristics to ensure that LPMCSes are formed around high-quality information. We then propose an intelligent sensor model for integrating this information into the AgentSpeak framework which is responsible for applying evidence propagation to construct compatible information, for performing context-dependent combination and for deriving beliefs for revising an agent’s belief base. Finally, we present a power grid scenario inspired by a real-world case study to demonstrate our work

Groundwater resources assessment using numerical model : a case study in low-lying coastal area.

The impacts of climate change and human pressure in groundwater have been greatest threats facing small islands. This paper represents a case study of groundwater responses towards the climate change and human pressures in Manukan Island Malaysia. SEAWAT-2000 was used for the simulations of groundwater response in study area. Simulations of six scenarios representing climate change and human pressures showed changes in hydraulic heads and chloride concentrations. Reduction in pumping rate and an increase in recharge rate can alter the bad effects of overdrafts in Manukan Island. In general, reduction in pumping rate and an increase in recharge rate are capable to restore and protect the groundwater resources in Manukan Island. Thus, for groundwater management options in Manukan Island, scenario 2 is capable to lessen the seawater intrusion into the aquifer and sustain water resources on a long-term basis. The selection of scenario 6 is the preeminent option during wet season. The output of this study provides a foundation which can be used in other small islands of similar hydrogeological condition for the purpose of groundwater resources protection