Using Dual-Language Books to Preserve Language & Culture in Alaska Native Communities

“Children learn their language on their mother’s lap.” This conventional wisdom from a Cup’ik Elder describes the approach used by many Alaska Native peoples to promote native language acquisition. Presumably, the children learn by listening to stories and tales from a trusted parent or caregiver. However, what happens when the caregiver does not speak the native language? This chapter describes an effort to address this issue while also promoting better educational outcomes by providing access to diverse dual-language books in Alaska Native languages through the use of a digital children’s library. Potential benefits from these efforts include an increase in resources for schools, a revitalization of Indigenous languages, and an increase in access, with hopes that future work will show evidence that using these dual-language books encourage greater parent support and involvement in education, support second language acquisition, and promote a strong sense of identity. Implications and future efforts follow.Ye

Actin-Bundling Protein TRIOBP Forms Resilient Rootlets of Hair Cell Stereocilia Essential for Hearing

Inner ear hair cells detect sound through deflection of mechanosensory stereocilia. Each stereocilium is supported by a paracrystalline array of parallel actin filaments that are packed more densely at the base, forming a rootlet extending into the cell body. The function of rootlets and the molecules responsible for their formation are unknown. We found that TRIOBP, a cytoskeleton-associated protein mutated in human hereditary deafness DFNB28, is localized to rootlets. In vitro, purified TRIOBP isoform 4 protein organizes actin filaments into uniquely dense bundles reminiscent of rootlets but distinct from bundles formed by espin, an actin crosslinker in stereocilia. We generated mutant Triobp mice (Triobp(Delta ex8/Delta ex8)) that are profoundly deaf. Stereocilia of Triobp(Delta ex8/Delta ex8) mice develop normally but fail to form rootlets and are easier to deflect and damage. Thus, F-actin bundling by TRIOBP provides durability and rigidity for normal mechanosensitivity of stereocilia and may contribute to resilient cytoskeletal structures elsewhere