31 research outputs found

    SociolingĂŒĂ­stica. MarĂ­a JosĂ© Serrano (2011)

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    Language making and ownership from the perspective of writing creoles

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    In this paper, I examine the ideologies and policies on writing creoles as examples of hitherto mostly unwritten languages and test cases for language making as defined by KrĂ€mer et al. (forthcoming 2022), also considering issues of language ownership. In socalled “Western ideologies” of what constitutes a language, writing plays an important role. Orthographies and the actors behind them are of interest as, for example, certain graphemes carry heavy sociopolitical connotations, which may emphasize the question of language ownership. I will briefly discuss the orthographies of four Western Caribbean English-lexifier creoles (Belize, Nicaragua, San AndrĂ©s-Providence, and LimĂłn) and their evolution over the past three decades in order to address these issues. A useful point of comparison is constituted by the orthographies devised for Haitian Creole and Jamaican.</p

    THE MAKING OF LANGUAGES AND NEW LITERACIES: SAN ANDRÉS-PROVIDENCE CREOLE WITH A VIEW ON JAMAICAN AND HAITIAN

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    The aim of this paper is to examine the idea of "language making" and new literacies in creole languages with a focus on San Andres-Providence Creole English. Jamaican and Haitian Creole are taken as points of comparison for their more advanced state of consolidation. Posts from Facebook groups gathered between February 2016 and July 2020 as the main source of data were complemented by 2015 data on San Andres linguistic landscapes. The main finding is that, due to a favorable change in language attitudes both locally and globally, San Andres-Providence Creole is entering into the domain of writing

    Language Making of Creoles in multilingual postcolonial societies

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    This article investigates Language Making processes in multilingual postcolonial societies where Creole languages are spoken. It raises the question whether or not Language Making in these settings differs from other contexts given the historical preconditions and social, economic, or political inequalities which persist after the colonial period. The paper discusses the potentials of Language Making to support or impede efforts of decolonization. With the help of examples from several Creole-speaking societies, it shows different approaches to conceptualizing Creole languages as linguistic entities with the creation or emergence of norms, different naming strategies or through language policy and planning. It examines the potential contribution of different agents of Language Making and illustrates cases in which Language Making is countered or languages are un-made. As a conclusion, the article shows that the concept of Language Making may need further expansion or nuancing in order to avoid a “Northern” or “Western” bias

    Las lenguas criollas: entre contacto, innovaciĂłn y marginalizaciĂłn

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    Variation and Evolution. Aspects of language contact and contrast across the Spanish-speaking world

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    In this paper, we discuss New Mochica as an example of language revival. New Mochica is definitely not the Mochica of the colonial or republican epoch of present-day Peru and the continuity of an already extinct language can be questioned. Van Coetsem’s (1988, 2000) framework of language contact explains why the contribution of the language revivalists’ dominant language, Spanish, has such a powerful impact on New Mochica, eradicating the central typological features of Mochica. On the other hand, the groups of language revivalists presented in this paper explore the linguistic resources at hand in creative ways. Based on this case study, we propose that language revival should be studied as distinct from language revitalization (cf. Zuckermann & Walsh, 2011), yet as related to overall processes of language making (HĂŒning & KrĂ€mer, 2018). Keywords: indigenous languages of Peru, language policy and planning, language revival, language making</p

    Language Making of Creoles in multilingual postcolonial societies

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    This article investigates Language Making processes in multilingual postcolonial societies where Creole languages are spoken. It raises the question whether or not Language Making in these settings differs from other contexts given the historical preconditions and social, economic, or political inequalities which persist after the colonial period. The paper discusses the potentials of Language Making to support or impede efforts of decolonization. With the help of examples from several Creole-speaking societies, it shows different approaches to conceptualizing Creole languages as linguistic entities with the creation or emergence of norms, different naming strategies or through language policy and planning. It examines the potential contribution of different agents of Language Making and illustrates cases in which Language Making is countered or languages are un-made. As a conclusion, the article shows that the concept of Language Making may need further expansion or nuancing in order to avoid a “Northern” or “Western” bias.</p

    Analysis of Genetic Variation in the Bovine SLC11A1 Gene, Its Influence on the Expression of NRAMP1 and Potential Association With Resistance to Bovine Tuberculosis

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    Bovine tuberculosis (bTB), caused by Mycobacterium bovis, is a chronic zoonotic disease where host genetics is thought to contribute to susceptibility or resistance. One of the genes implicated is the SLC11A1 gene, that encodes for the natural resistance-associated macrophage protein 1 (NRAMP1). The aim of this study was to identify SLC11A1 polymorphisms and to investigate any resulting functional differences in NRAMP1 expression that might be correlated with resistance/susceptibility to M. bovis infection. Sequencing of the SLC11A1 gene in cDNA isolated from Brown Swiss, Holstein Friesian, and Sahiwal cattle identified five single nucleotide polymorphisms (SNPs) in the coding region, but only one of these (SNP4, c.1066C>G, rs109453173) was present in all three cattle breeds and therefore warranted further investigation. Additionally, variations of 10, 11, and 12 GT repeats were identified in a microsatellite (MS1) in the SLC11A1 3â€ČUTR. Measurement of NRAMP1 expression in bovine macrophages by ELISA showed no differences between cells generated from the different breeds. Furthermore, variations in the length of the MS1 microsatellite did not impact on NRAMP1 protein expression as analyzed by luciferase reporter assay. However, further analysis of the ELISA data identified that the presence of the alternative G allele at SNP4 was associated with increased expression of NRAMP1 in bovine macrophages. Since NRAMP1 has been shown to influence the survival of intracellular pathogens such as M. bovis through the sequestering of iron, it is possible that cattle expressing the alternative G allele might have an increased resistance to bTB through increased NRAMP1 expression in their macrophages

    Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality.

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    Recent evidence suggests that several cattle breeds may be more resistant to infection with the zoonotic pathogen Mycobacterium bovis. Our data presented here suggests that the response to mycobacterial antigens varies in macrophages generated from Brown Swiss (BS) and Holstein Friesian (HF) cattle, two breeds belonging to the Bos taurus family. Whole genome sequencing of the Brown Swiss genome identified several potential candidate genes, in particular Toll-like Receptor-2 (TLR2), a pattern recognition receptor (PRR) that has previously been described to be involved in mycobacterial recognition. Further investigation revealed single nucleotide polymorphisms (SNP) in TLR2 that were identified between DNA isolated from cells of BS and HF cows. Interestingly, one specific SNP, H326Q, showed a different genotype frequency in two cattle subspecies, Bos (B.) taurus and Bos indicus. Cloning of the TLR2 gene and subsequent gene-reporter and chemokine assays revealed that this SNP, present in BS and Bos indicus breeds, resulted in a significantly higher response to mycobacterial antigens as well as tri-acylated lipopeptide ligands in general. Comparing wild-type and H326Q containing TLR2 responses, wild-type bovine TLR2 response showed clear, diminished mycobacterial antigen responses compared to human TLR2, however bovine TLR2 responses containing H326Q were found to be partially recovered compared to human TLR2. The creation of human:bovine TLR2 chimeras increased the response to mycobacterial antigens compared to the full-length bovine TLR2, but significantly reduced the response compared to the full-length human TLR2. Thus, our data, not only present evidence that TLR2 is a major PRR in the mammalian species-specific response to mycobacterial antigens, but furthermore, that there are clear differences between the response seen in different cattle breeds, which may contribute to their enhanced or reduced susceptibility to mycobacterial infection

    Single Nucleotide Polymorphisms in the Bovine TLR2 Extracellular Domain Contribute to Breed and Species-Specific Innate Immune Functionality

    Get PDF
    Recent evidence suggests that several cattle breeds may be more resistant to infection with the zoonotic pathogen Mycobacterium bovis. Our data presented here suggests that the response to mycobacterial antigens varies in macrophages generated from Brown Swiss (BS) and Holstein Friesian (HF) cattle, two breeds belonging to the Bos taurus family. Whole genome sequencing of the Brown Swiss genome identified several potential candidate genes, in particular Toll-like Receptor-2 (TLR2), a pattern recognition receptor (PRR) that has previously been described to be involved in mycobacterial recognition. Further investigation revealed single nucleotide polymorphisms (SNP) in TLR2 that were identified between DNA isolated from cells of BS and HF cows. Interestingly, one specific SNP, H326Q, showed a different genotype frequency in two cattle subspecies, Bos (B.) taurus and Bos indicus. Cloning of the TLR2 gene and subsequent gene-reporter and chemokine assays revealed that this SNP, present in BS and Bos indicus breeds, resulted in a significantly higher response to mycobacterial antigens as well as tri-acylated lipopeptide ligands in general. Comparing wild-type and H326Q containing TLR2 responses, wild-type bovine TLR2 response showed clear, diminished mycobacterial antigen responses compared to human TLR2, however bovine TLR2 responses containing H326Q were found to be partially recovered compared to human TLR2. The creation of human:bovine TLR2 chimeras increased the response to mycobacterial antigens compared to the full-length bovine TLR2, but significantly reduced the response compared to the full-length human TLR2. Thus, our data, not only present evidence that TLR2 is a major PRR in the mammalian species-specific response to mycobacterial antigens, but furthermore, that there are clear differences between the response seen in different cattle breeds, which may contribute to their enhanced or reduced susceptibility to mycobacterial infection
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