Effect of maternal calcium intake during pregnancy on children's blood pressure: A systematic review of the literature

<p>Abstract</p> <p>Background</p> <p>Calcium supplementation during pregnancy has been shown to reduce the incidence of hypertension in the mother, but the effects on the offspring are uncertain. Assessing the impact on the offspring is very important given the now large body of evidence indicating that blood pressure levels in childhood and young adulthood can be influenced by factors operating during fetal life. We conducted a systematic review of the literature to summarize the evidence supporting an association between maternal dietary calcium intake during pregnancy and blood pressure in the offspring.</p> <p>Methods</p> <p>A systematic review was performed to identify randomized, quasi-randomized and cohort studies reporting the relationship between offspring blood pressure or incidence of hypertension and levels of maternal dietary calcium intake during pregnancy, either from supplements (i.e. pills) or food. MEDLINE, EMBASE and the Cochrane Library Registry were searched for relevant trials.</p> <p>Results</p> <p>Two randomized trial and three observational studies were identified and included in this review. In 4 of the 5 studies, loss to follow-up was a serious concern. There was heterogeneity between the studies, particularly those conducted on children below 12 month of age. Results were more consistent among the studies including older children (1 to 9 years) where a higher maternal calcium intake was associated with a reduction of -1.92 mm Hg (95% CI -3.14 to -0.71) in offspring systolic blood pressure. One large randomized trial found a clinically and statistically significant reduction in the incidence of hypertension in 7-year-old children (RR = 0.59, 95% CI 0.39 to 0.90).</p> <p>Conclusion</p> <p>There is evidence in the literature to support an association between maternal calcium intake during pregnancy and offspring blood pressure. However, more research is needed to confirm these finding given the small sample sizes and the methodological problems in many of the studies conducted so far. More studies on populations with calcium deficit are also needed. If confirmed, these findings could have important public health implications. Calcium supplementation during pregnancy is simple and inexpensive and may be a way to reduce the risk of hypertension and its sequels in the next generation.</p

Modelagem estatística em estudos epidemiológicos : o modelo logístico

Orientador: Euclydes Custodio de LimaDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Matematica, Estatistica e Computação CientificaResumo: Não informado.Abstract: Not informed.MestradoMestre em Estatístic

Learning from success cases: ecological analysis of potential pathways to universal access to family planning care in low- and middle-income countries. [version 3; peer review: 2 approved]

Background  Universal access to family planning services is a well-recognized human right and several countries and organizations are committed to this goal. Our objective was to identify countries who improved family planning coverage in the last 40 years and investigate which contexts enabled those advances.  Methods  Analyses were based on data from publicly available national health surveys carried out since 1986 in Egypt, Ethiopia, Rwanda, Afghanistan, Brazil, and Ecuador, selected based on previous evidence. We estimated demand for family planning satisfied with modern methods (mDFPS) for each country and explored inequalities in terms of wealth, women’s education, and women’s age. We also explored contextual differences in terms of women’s empowerment, percentage of population living in extreme poverty, and share of each type of contraceptive. To better understand political and sociocultural contexts, country case studies were included, based on literature review.  Results  Patterns of mDFPS increase were distinct in the selected countries. Current level of mDFPS coverage ranged between 94% in Brazil and 38% in Afghanistan. All countries experienced an important reduction in both gender inequality and extreme poverty. According to the share of each type of contraceptive, most countries presented higher use of short-acting reversible methods. Exceptions were Ecuador, where the most used method is sterilization, and Egypt, which presented higher use of long-acting reversible methods. In the first years analyzed, all countries presented huge gaps in coverage according to wealth, women’s education and women’s age. All countries managed to increase coverage over recent years, especially among women from the more disadvantaged groups.  Conclusions  Family planning coverage increased along with reductions in poverty and gender inequality, with substantial increases in coverage among the most disadvantaged in recent years. Policies involving primary health care services, provision of various methods, and high quality training of health providers are crucial to increase coverage

FISIOTERAPIA CARDIORRESPIRATÓRIA: IMPLANTAÇÃO DE UM SERVIÇO AMBULATORIAL

As doenças cardiovasculares e respiratórias são um problema de saúde pública, visto que são altamente prevalentes e apresentam alta morbidade e mortalidade. O diagnóstico precoce e a intervenção adequada são fundamentais no aumento da sobrevida e melhora da qualidade de vida. Diversos estudos têm apontado que a assistência fisioterapêutica prestada nas doenças cardiovasculares e respiratórias é efetiva e deve ser incentiva e apoiada em todos os níveis de assistência à saúde. Atualmente, a maioria dos serviços de fisioterapia cardiorrespiratória ocorre dentro do ambiente hospitalar. Desse modo, muitos pacientes não recebem assistência fisioterapêutica especializada, incluindo aqueles que recebem alta hospitalar. O objetivo da implantação de um serviço ambulatorial de fisioterapia cardiorrespiratória é fornecer atendimento fisioterapêutico especializado para pessoas portadoras de doenças cardiovasculares e respiratórias. O Curso de Fisioterapia da Unoesc de Joaçaba dispõe de atendimento em fisioterapia cardiorrespiratória no ambiente hospitalar. Por meio do levantamento da demanda de pacientes que necessitam do atendimento ambulatorial, o colegiado do Curso de Fisioterapia aventou a possibilidade de organizar dentro de um dos estágios obrigatórios a possibilidade de contemplar também a atuação em fisioterapia cardiorrespiratória ambulatorial. Mediante discussões realizadas com o núcleo docente estruturante do Curso e também com os professores supervisores de estágio, foram reorganizados e readequados os estágios para que os pacientes com doenças cardiovasculares e respiratórias pudessem também ser beneficiados com o atendimento da fisioterapia ambulatorial. Além dos procedimentos pedagógicos e operacionais para disponibilizar o atendimento, foi realizado contato com serviços de saúde e profissionais da área e divulgação na mídia, incluindo a rádio universitária e rádio comercial de abrangência regional. Os atendimentos iniciaram no início do segundo semestre de 2015 e tem-se por objetivo realizar dois atendimentos por semana para cada paciente.Palavras-chave: Fisioterapia cardiorrespiratória. Doenças cardiovasculares. Doenças respiratórias. Atendimento ambulatorial

Are inequities decreasing? Birth registration for children under five in low-income and middle-income countries, 1999-2016.

INTRODUCTION: Although global birth registration coverage has improved from 58% to 71% among children under five globally, inequities in birth registration coverage by wealth, urban/rural location, maternal education and access to a health facility persist. Few studies examine whether inequities in birth registration in low-income and middle-income countries have changed over time. METHODS: We combined information on caregiver reported birth registration of 1.6 million children in 173 publicly available, nationally representative Demographic Health Surveys and Multiple Indicator Cluster Surveys across 67 low-income and middle-income countries between 1999 and 2016. For each survey, we calculated point estimates and 95% CIs for the percentage of children under 5 years without birth registration on average and stratified by sex, urban/rural location and wealth. For each sociodemographic variable, we estimated absolute measures of inequality. We then examined changes in non-registration and inequities between surveys, and annually. RESULTS: 14 out of 67 countries had achieved complete birth registration. Among the remaining 53 countries, 39 countries successfully decreased the percentage of children without birth registration. However, this reduction occurred alongside statistically significant increases in wealth inequities in 9 countries and statistically significant decreases in 10 countries. At the most recent survey, the percentage of children without birth registration was greater than 50% in 16 out of 67 countries. CONCLUSION: Although birth registration improved on average, progress in reducing wealth inequities has been limited. Findings highlight the importance of monitoring changes in inequities to improve birth registration, to monitor Sustainable Development Goal 16.9 and to strengthen Civil Registration and Vital Statistics systems

Focus and coverage of Bolsa Família Program in the Pelotas 2004 birth cohort

OBJECTIVE To describe the focalization and coverage of Bolsa Família Program among the families of children who are part of the 2004 Pelotas birth cohort (2004 cohort). METHODS The data used derives from the integration of information from the 2004 cohort and the Cadastro Único para Programas Sociais do Governo Federal (CadÚnico – Register for Social Programs of the Federal Government), in the 2004-2010 period. We estimated the program coverage (percentage of eligible people who receive the benefit) and its focus (proportion of eligible people among the beneficiaries). We used two criteria to define eligibility: the per capita household income reported in the cohort follow-ups and belonging to the 20% poorest families according to the National Economic Indicator (IEN), an asset index. RESULTS Between 2004 and 2010, the proportion of families in the cohort that received the benefit increased from 11% to 34%. We observed an increase in all wealth quintiles. In 2010, by income and wealth quintiles (IEN), 62%-72% of the families were beneficiaries among the 20% poorest people, 2%-5% among the 20% richest people, and about 30% of families of the intermediate quintile. According to household income (minus the benefit) 29% of families were eligible in 2004 and 16% in 2010. By the same criteria, the coverage of the program increased from 43% in 2004 to 71% in 2010. In the same period, by the wealth criterion (IEN), coverage increased from 29% to 63%. The focalization of the program decreased from 78% in 2004 to 32% in 2010 according to income, and remained constant (37%) according to the IEN. CONCLUSIONS Among the families of the 2004 cohort, there was a significant increase in the program coverage, from its inception until 2010, when it was near 70%. The focus of the program was below 40% in 2010, indicating that more than half of the beneficiaries did not belong to the target population.OBJETIVO Descrever a focalização e a cobertura do Programa Bolsa Família nas famílias de crianças que fazem parte da coorte de nascimentos de Pelotas, 2004 (coorte de 2004). MÉTODOS Os dados utilizados derivam da integração de informações da coorte de 2004 e do Cadastro Único para Programas Sociais do Governo Federal, no período de 2004 a 2010. Estimamos a cobertura do programa (percentual de elegíveis que recebem bolsa) e seu foco (proporção de elegíveis entre os beneficiários). Utilizamos dois critérios para definir elegibilidade: a renda familiar per capita relatada nas avaliações da coorte e pertencer aos 20,0% mais pobres pela classificação do Indicador Econômico Nacional, um índice de bens. RESULTADOS Entre 2004 e 2010, a proporção de famílias beneficiárias da coorte passou de 11% para 34%. Houve aumento em todos os quintis de riqueza. Em 2010, por quintis de renda e Indicador Econômico Nacional, 62%-72% das famílias eram beneficiárias entre os 20% mais pobres, 2%-5% entre os 20% mais ricos, e cerca de 30% das famílias do quintil intermediário. Pelo critério de renda familiar, excluindo-se o valor do benefício do programa, 29% das famílias eram elegíveis em 2004 e 16% em 2010. Pelo mesmo critério, a cobertura do programa passou de 43% em 2004 para 71% em 2010. No mesmo período, pelo critério de riqueza (Indicador Econômico Nacional), a cobertura passou de 29% para 63%. A focalização do programa caiu de 78% em 2004 para 32% em 2010 de acordo com a renda e permaneceu constante (37%) de acordo com o Indicador Econômico Nacional. CONCLUSÕES Entre as famílias da coorte de 2004, observa-se aumento importante da cobertura do programa, de seu início até 2010, quando ficou perto de 70%. O foco do programa ficou abaixo de 40% em 2010, indicando que mais da metade dos beneficiários não pertencem à população alvo

Discriminação explícita e saúde: desenvolvimento e propriedades psicométricas de um instrumento

OBJECTIVE: To develop an instrument to assess discrimination effects on health outcomes and behaviors, capable of distinguishing harmful differential treatment effects from their interpretation as discriminatory events. METHODS: Successive versions of an instrument were developed based on a systematic review of instruments assessing racial discrimination, focus groups and review by a panel comprising seven experts. The instrument was refined using cognitive interviews and pilot-testing. The final version of the instrument was administered to 424 undergraduate college students in the city of Rio de Janeiro, Southeastern Brazil, in 2010. Structural dimensionality, two types of reliability and construct validity were analyzed. RESULTS: Exploratory factor analysis corroborated the hypothesis of the instrument's unidimensionality, and seven experts verified its face and content validity. The internal consistency was 0.8, and test-retest reliability was higher than 0.5 for 14 out of 18 items. The overall score was higher among socially disadvantaged individuals and correlated with adverse health behaviors/conditions, particularly when differential treatments were attributed to discrimination. CONCLUSIONS: These findings indicate the validity and reliability of the instrument developed. The proposed instrument enables the investigation of novel aspects of the relationship between discrimination and health.OBJETIVO: Desarrollar instrumento para evaluar los efectos de experiencias discriminatorias sobre condiciones y comportamientos en salud, distinguiendo efectos patológicos de la exposición a tratamientos diferenciales de su interpretación como eventos discriminatorios. MÉTODOS: Versiones sucesivas del instrumento fueron elaboradas con base en una revisión sistemática de la literatura sobre escalas de discriminación, grupos focales y apreciación por un panel de siete especialistas. El refinamiento del instrumento fue alcanzado por medio de entrevistas cognitivas y estudio piloto, de modo que la versión final fue aplicada en 424 estudiantes de pregrado en Rio de Janeiro, sureste de Brasil, en 2010. La estructura dimensional, dos tipos de confiabilidad y validez del constructo fueron evaluadas. RESULTADOS: El análisis factorial exploratorio corroboró la hipótesis de unidimensionalidad del instrumento y siete especialistas indicaron que el presentaba validez de orientación y contenido. La consistencia interna fue de 0,8 y la confiabilidad de la prueba y re-evaluación fue mayor a 0,5 para 14 de los 18 itens. El escore general fue más alto en individuos socialmente desafortunados y se asoció con comportamientos/condiciones de salud adversos, especialmente al considerarse tratamientos atribuidos a la discriminación. CONCLUSIONES: Estos resultados sugieren validez y confiabilidad del instrumento desarrollado. La escala presentada permitirá investigar aspectos innovadores de las relaciones entre discriminación y salud.OBJETIVO: Desenvolver instrumento para avaliar os efeitos de experiências discriminatórias sobre condições e comportamentos em saúde, capaz de distinguir efeitos patológicos da exposição a tratamentos diferenciais de sua interpretação como eventos discriminatórios. MÉTODOS: Versões sucessivas do instrumento foram elaboradas com base em uma revisão sistemática da literatura sobre escalas de discriminação, grupos focais e apreciação por um painel de sete especialistas. O refinamento do instrumento foi atingido por meio de entrevistas cognitivas e estudo-piloto, de modo que sua versão final foi aplicada em 424 estudantes de graduação no Rio de Janeiro, RJ, em 2010. A estrutura dimensional, dois tipos de confiabilidade e validade de construto foram avaliadas. RESULTADOS: A análise fatorial exploratória corroborou a hipótese de unidimensionalidade do instrumento e sete especialistas indicaram que este apresentava validade de face e conteúdo. A consistência interna foi de 0,8 e a confiabilidade teste-reteste foi maior do que 0,5 para 14 dos 18 itens. O escore foi estatisticamente mais alto em indivíduos socialmente desprivilegiados e associou-se com comportamentos/condições de saúde adversos, especialmente quando tratamentos atribuídos à discriminação foram considerados. CONCLUSÕES: Estes resultados sugerem validade e confiabilidade do instrumento desenvolvido. A escala apresentada permitirá investigar aspectos inovadores das relações entre discriminação e saúde

The SWPER index for women’s empowerment in Africa: development and validation of an index based on survey data

Background The Sustainable Development Goals strongly focus on equity. Goal 5 explicitly aims to empower all women and girls, reinforcing the need to have a reliable indicator to track progress. Our objective was to develop a novel women's empowerment indicator from widely available data sources, broadening opportunities for monitoring and research on women's empowerment. Methods We used Demographic and Health Survey data from 34 African countries, targeting currently partnered women. We identified items related to women's empowerment present in most surveys, and used principal component analysis to extract the components. We carried out a convergent validation process using coverage of three health interventions as outcomes; and an external validation process by analysing correlations with the Gender Development Index. Findings 15 items related to women's empowerment were selected. We retained three components (50% of total variation) which, after rotation, were identified as three dimensions of empowerment: attitude to violence, social independence, and decision making. All dimensions had moderate to high correlation with the Gender Development Index. Social independence was associated with higher coverage of maternal and child interventions; attitude to violence and decision making were more consistently associated with the use of modern contraception. Interpretation The index, named Survey-based Women's emPowERment index (SWPER), has potential to widen the research on women's empowerment and to give a better estimate of its effect on health interventions and outcomes. It allows within-country and between-country comparison, as well as time trend analysis, which no other survey-based index provides