Agro-morphological characterization of selected varieties of vegetable cowpea [Vigna unguiculata (L.) Walp.] in Burkina Faso

Vegetable Cowpea (Vigna unguiculata) is one of the neglected legumes in Burkina Faso, and as a result, its genetic diversity remains poorly known. The main aim of this study was to know its genetic variability through an agro-morphological characterization. Twenty vegetable cowpea varieties were evaluated at the Kamboinsé Environmental, Agricultural and Training Research Center following a three-replication Fischer block design under rainfed conditions. Fifteen quantitative and nine qualitative variables were collected and subjected to various statistical analyses. Analysis of variance was significant for the variables 50% flowering, vegetable cowpea date, number of pods obtained per plant, number of seeds per pod, fresh pod weight, fresh pod yield, pod length, plant height, seed length and chlorophyll content. Strong correlations were also reported between the various variables. The observed diversity is structured in three morphological groups viz., Group 1 consists of individuals with early flowering, high chlorophyll content and the number of pods obtained per plant. Group 2 brings together the varieties of average agronomic performance for pod length, the number of pods per plant, number of days at 95% maturity, fresh pod weight, yield of fresh pods and group 3 of varieties with long pods, early green date, high pod weight and good fresh pod yield. Among the tested varieties, the varieties IT83S-872 (30 pods), IT84S-2246 (27 pods), Baguette (25 pods), IT83S-818 (26 pods), and IT85F-2682 (24 pods) stood out for their high pod production. In addition, the varieties of vegetable cowpea baguette, baguette grimpant, Telma, and IT83S-911 showed the best performance in terms of early vegetable cowpea date stage, longest pods, highest pod weight and best yield of fresh pods. The high genetic variability level within the tested varieties could be exploited in future green cowpea breeding programmes

Seroprevalence of fecal-oral transmitted hepatitis A and E virus antibodies in Burkina Faso.

Hepatitis A virus (HAV) and hepatitis E virus (HEV) infections occur chiefly as a result of unhygienic conditions. The purpose of this study was to assess the seroprevalence of antibodies to both viruses in central Burkina Faso in the absence of a recorded hepatitis epidemic. Serum samples from 178 blood donors (131 males and 47 females) and from 189 pregnant women were collected from November 2010 to March 2012, at blood banks and medical centers in Burkina Faso. An immunochromatography test was used to screen for Anti-HAV IgM and IgG in a subgroup of 91 blood donors and 100 pregnant women. The seroprevalence of anti-HAV IgG was 14.3% [CI95, 7.1-21.4%] for all blood donors and 23% [CI95, 14.8-31.2%] for pregnant women. Anti-HEV IgG were detected using the ELISA kits Dia.pro and Wantai and were found in 19.1% [CI95, 13.3-24.9%] of the blood donors and 11.6% [CI95, 7.1-16.2%] of the pregnant women. The seroprevalences of anti-HAV and anti-HEV IgGs did not differ significantly between men and women blood donors. Anti-HAV IgM was detected in 3.3% of the blood donors and in 2% of the pregnant women. These findings for asymptomatic individuals indicate that the HAV and HEV circulate at low but significant levels. This is the first evaluation of the acute hepatitis virus burden in Burkina Faso and the underlying epidemiologic status of the population

Modelling factors associated with therapeutic inertia in hypertensive patients: Analysis using repeated data from a hospital registry in West Africa

International audienceThe proportion of poorly controlled hypertensives still remains high in the general African population. This is largely due to therapeutic inertia (TI), defined as the failure to intensify or modify treatment in a patient with poorly controlled blood pressure (BP). The objective of this study was to identify the determinants of TI. We conducted a retrospective cohort study from March 2012 to February 2014 of hypertensive patients followed during 4 medical visits. The TI score was the number of visits with TI divided by the number of visits where a therapeutic change was indicated. A random-effects logistic model was used to identify the determinants of TI. A total of 200 subjects were included, with a mean age of 57.98 years and 67% men. The TI score was measured at 85.57% (confidence interval [CI] 95% = [82.41-88.92]). Measured individual heterogeneity was significantly significant (0.78). Three factors were associated with treatment inertia, namely the number of antihypertensive drugs (odd ratios [OR] = 1.27; CI = [1.02-1.58]), the time between consultations (OR = 0.94; CI = [0.91-0.97]), and treatment noncompliance (OR = 15.18; CI = [3.13-73.70]). The random-effects model performed better in predicting high-risk patients with TI than the classical logistic model (P value < .001). Our study showed a high TI score in patients followed in cardiology in Burkina Faso. Reduction of the TI score through targeted interventions is necessary to better control hypertension in our cohort patient

Modelling factors associated with therapeutic inertia in hypertensive patients: Analysis using repeated data from a hospital registry in West Africa

International audienceThe proportion of poorly controlled hypertensives still remains high in the general African population. This is largely due to therapeutic inertia (TI), defined as the failure to intensify or modify treatment in a patient with poorly controlled blood pressure (BP). The objective of this study was to identify the determinants of TI. We conducted a retrospective cohort study from March 2012 to February 2014 of hypertensive patients followed during 4 medical visits. The TI score was the number of visits with TI divided by the number of visits where a therapeutic change was indicated. A random-effects logistic model was used to identify the determinants of TI. A total of 200 subjects were included, with a mean age of 57.98 years and 67% men. The TI score was measured at 85.57% (confidence interval [CI] 95% = [82.41-88.92]). Measured individual heterogeneity was significantly significant (0.78). Three factors were associated with treatment inertia, namely the number of antihypertensive drugs (odd ratios [OR] = 1.27; CI = [1.02-1.58]), the time between consultations (OR = 0.94; CI = [0.91-0.97]), and treatment noncompliance (OR = 15.18; CI = [3.13-73.70]). The random-effects model performed better in predicting high-risk patients with TI than the classical logistic model (P value < .001). Our study showed a high TI score in patients followed in cardiology in Burkina Faso. Reduction of the TI score through targeted interventions is necessary to better control hypertension in our cohort patient

Modelling factors associated with therapeutic inertia in hypertensive patients: Analysis using repeated data from a hospital registry in West Africa

International audienceThe proportion of poorly controlled hypertensives still remains high in the general African population. This is largely due to therapeutic inertia (TI), defined as the failure to intensify or modify treatment in a patient with poorly controlled blood pressure (BP). The objective of this study was to identify the determinants of TI. We conducted a retrospective cohort study from March 2012 to February 2014 of hypertensive patients followed during 4 medical visits. The TI score was the number of visits with TI divided by the number of visits where a therapeutic change was indicated. A random-effects logistic model was used to identify the determinants of TI. A total of 200 subjects were included, with a mean age of 57.98 years and 67% men. The TI score was measured at 85.57% (confidence interval [CI] 95% = [82.41-88.92]). Measured individual heterogeneity was significantly significant (0.78). Three factors were associated with treatment inertia, namely the number of antihypertensive drugs (odd ratios [OR] = 1.27; CI = [1.02-1.58]), the time between consultations (OR = 0.94; CI = [0.91-0.97]), and treatment noncompliance (OR = 15.18; CI = [3.13-73.70]). The random-effects model performed better in predicting high-risk patients with TI than the classical logistic model (P value < .001). Our study showed a high TI score in patients followed in cardiology in Burkina Faso. Reduction of the TI score through targeted interventions is necessary to better control hypertension in our cohort patient

INACTIVITE PHYSIQUE ET QUALITE DE VIE DES PERSONNES AGEES DANS LA VILLE DE OUAGADOUGOU, BURKINA FASO / PHYSICAL INACTIVITY AND QUALITY OF LIFE OF OLDER PEOPLE IN THE CITY OF OUAGADOUGOU, BURKINA FASO

Objectif : La croissance du nombre des personnes âgées (PA) ou encore le phénomène de vieillissement de la population touche à présent les pays à revenu faible. Notre travail a pour objectif d’analyser la relation entre le niveau d’activités physique des PA et leur qualité de vie. Matériel et méthode : nous avons réalisé une étude transversale descriptive et analytique par questionnaire auto-administré. L’enquête a été réalisée au moyen de questionnaires validés d’activité physique de Dijon et du WHOQUOL-BREF (OMS) auprès des sujets d’au moins 60 ans choisis de façon raisonnée dans les lieux de culte, les grains de jeux de société et les associations des PA dans la ville de Ouagadougou. Les logiciels CSPRO 7.0 et STATA 14 ont été utilisés pour la saisie et l’analyse des données. Un modèle de régression multiple a été utilisé pour déterminer la relation entre l’activité physique des personnes âgées et leur qualité de vie. Résultats : Au total 356 sujets d’au moins 60 ans ont été inclus dans notre étude. La tranche d’âge de 60 à 75 ans était la plus représentée (71,91%) et 66,57% des sujets étaient de sexe masculin. Les sujets mariés représentaient 65,17 % de l’échantillon. Les 2/3 des sujets avaient une bonne qualité de vie et moins du tiers avait un niveau d’activité faible. Le modèle final de régression logistique montrait que la qualité de vie augmente avec le niveau d’activité physique ajustée sur certaines variables (OR moyen= 4,88 [1,94-12,23] ; OR élevé=4,70 [2,51-8,80] par rapport au niveau faible). Conclusion : Ces résultats révèlent des scores d’activité physique et de qualité de vie faibles et un état de santé très morbide. L’activité physique est un outil déterminant de la qualité de vie chez les PA au Burkina Faso. Objective: The growth in the number of elderly people or the phenomenon of population aging is now affecting low-income countries. Our work aims to analyze the relationship between the level of physical activity of the elderly and their quality of life. Material and method: We carried out a descriptive and analytical cross-sectional study by self-administered questionnaire. The survey was carried out using validated Dijon and WHOQUOL-BREF physical activity questionnaires among subjects aged at least 60 years selected in a reasoned manner in places of worship, board game centers and associations of the elderly in the city of Ouagadougou. CSPRO 7.0 and STATA 14 software were used for data entry and analysis. A multiple regression model was used to determine the relationship between the physical activity of the elderly and their quality of life. Results: A total of 356 subjects at least 60 years old were included in our study. The age range of 60 to 75 years was the most represented (71.91%) and 66.57% of the subjects were male. Married subjects represented 65.17% of the sample. Two thirds of the subjects had a good quality of life and less than one third had a low activity level. The final logistic regression model showed that quality of life increased with activity level adjusted for certain variables (mean OR=4.88 [1.94-12.23]; high OR=4.70 [2.51-8.80] vs low level). Conclusion: These results reveal low physical activity and quality of life scores and a highly morbid health status. Physical activity is a determinant of quality of life in the elderly in Burkina Faso. Article visualizations

Selection and validation of marker set for selection of resistant varieties of cowpea to Cowpea Aphid-borne Mosaic Virus (CABMV) in Burkina Faso

Objective: This study aims to validate of marker set for selection of resistant varieties of Cowpea Aphid-borneMosaic Virus.Methodology and results: A molecular characterization of five genotypes using seventeen (17) SSR markers was carried out.Conclusion and application of results: This study make it possible to identify four (4) polymorphic microsatellite markers (VM30, VM33, VM68 and VM70), that is to say a rate of 23, 52% of polymorphism versus 76, 47% of monomorphism. Two of the polymorphic markers- VM68 and VM30 were submitted to the test of validation. At the end of this test, VM68 was codominant, because it makes it possible to distinguish the heterozygous individuals (F1, BC1 F1) from the homozygous individuals (F2) while the marker VM30 was dominating. The marker VM68 was validated and proposed in selection assisted by the markers of cowpea for resistance to CABMV.Keywords: cowpea, Cowpea Aphid-borne Mosaic Virus ((CABMV), Microsatellites, Validation, Burkina Fas

Modelling factors associated with therapeutic inertia in hypertensive patients: Analysis using repeated data from a hospital registry in West Africa

International audienceThe proportion of poorly controlled hypertensives still remains high in the general African population. This is largely due to therapeutic inertia (TI), defined as the failure to intensify or modify treatment in a patient with poorly controlled blood pressure (BP). The objective of this study was to identify the determinants of TI. We conducted a retrospective cohort study from March 2012 to February 2014 of hypertensive patients followed during 4 medical visits. The TI score was the number of visits with TI divided by the number of visits where a therapeutic change was indicated. A random-effects logistic model was used to identify the determinants of TI. A total of 200 subjects were included, with a mean age of 57.98 years and 67% men. The TI score was measured at 85.57% (confidence interval [CI] 95% = [82.41-88.92]). Measured individual heterogeneity was significantly significant (0.78). Three factors were associated with treatment inertia, namely the number of antihypertensive drugs (odd ratios [OR] = 1.27; CI = [1.02-1.58]), the time between consultations (OR = 0.94; CI = [0.91-0.97]), and treatment noncompliance (OR = 15.18; CI = [3.13-73.70]). The random-effects model performed better in predicting high-risk patients with TI than the classical logistic model (P value < .001). Our study showed a high TI score in patients followed in cardiology in Burkina Faso. Reduction of the TI score through targeted interventions is necessary to better control hypertension in our cohort patient

Prevalence of anti-HAV IgG and IgM in pregnant women and blood donors.

<p>Prevalence of anti-HAV IgG and IgM in pregnant women and blood donors.</p