R.V. Sonne New Vent Survey SO191. Multi-Channel Seismic Reflection Regional Survey

German Research Vessel R.V. Sonne visited New Zealand early this year to initiate a large collaborative research program involving IFM-GEOMAR (Germany), GNS Science and a number of New Zealand university. The aim of the project is to study gas hydrates in the offshore region of the North Island east coast, and in particular, to investigate local and regional processes of methane transport and the characterization of facies at cold vents and gas hydrate deposits along the Hikurangi margin. The survey included three legs from 11 January to 23 March 2007, during which a variety of geophysical, geochemical, biological and environmental data where acquired. The geophysical data will help investigate the structures, fluid flow conduits and possible connections to deeper fluid sources of vent sites

CBT repackaged or a novel treatment? The Lightning Process® compared with specialist medical care for paediatric Chronic Fatigue Syndrome.

RationaleUK specialist medical care (SMC) for paediatric Chronic Fatigue Syndrome (CFS/ME) includes behavioural approaches (Graded Exercise Therapy; Activity Management) and Cognitive Behavioural Therapy for fatigue (CBT-F). Treatment is suboptimal with a third of children not recovering after 6 months of SMC. Many families seek alternative treatments at personal cost, including the Lightning Process (LP). Evidence shows LP can improve patient outcomes, though this intervention is not widely known/understood.ObjectivesTo describe LP in comparison with SMC approaches in order to identify distinct elements, inform clinicians about treatment options, and generate hypotheses around effectiveness.MethodsTheoretical comparison including stakeholder consultation.ResultsWhile overlaps with SMC approaches were identified, and CBT-F in particular, distinct elements of LP were its focus on language style, neurophysiological rationale, affective/physiological change technique and mode of delivery.ConclusionThis theoretical comparison identified distinct elements of LP which could be explored in future interventions or research aiming to improve clinical outcomes for children with CFS/ME, and informs clinicians about treatment options available for families

Galaxy Zoo: The large-scale spin statistics of spiral galaxies in the Sloan Digital Sky Survey

We re-examine the evidence for a violation of large-scale statistical isotropy in the distribution of projected spin vectors of spiral galaxies. We have a sample of $\sim 37,000$ spiral galaxies from the Sloan Digital Sky Survey, with their line of sight spin direction confidently classified by members of the public through the online project Galaxy Zoo. After establishing and correcting for a certain level of bias in our handedness results we find the winding sense of the galaxies to be consistent with statistical isotropy. In particular we find no significant dipole signal, and thus no evidence for overall preferred handedness of the Universe. We compare this result to those of other authors and conclude that these may also be affected and explained by a bias effect.Comment: Accepted for publication in MNRAS. 8 pages, 5 figure

Cost-Effectiveness of Treating Upper Limb Spasticity Due to Stroke with Botulinum Toxin Type A: Results from the Botulinum Toxin for the Upper Limb after Stroke (BoTULS) Trial

Stroke imposes significant burdens on health services and society, and as such there is a growing need to assess the cost-effectiveness of stroke treatment to ensure maximum benefit is derived from limited resources. This study compared the cost-effectiveness of treating post-stroke upper limb spasticity with botulinum toxin type A plus an upper limb therapy programme against the therapy programme alone. Data on resource use and health outcomes were prospectively collected for 333 patients with post-stroke upper limb spasticity taking part in a randomized trial and combined to estimate the incremental cost per quality adjusted life year (QALY) gained of botulinum toxin type A plus therapy relative to therapy alone. The base case incremental cost-effectiveness ratio (ICER) of botulinum toxin type A plus therapy was £93,500 per QALY gained. The probability of botulinum toxin type A plus therapy being cost-effective at the England and Wales cost-effectiveness threshold value of £20,000 per QALY was 0.36. The point estimates of the ICER remained above £20,000 per QALY for a range of sensitivity analyses, and the probability of botulinum toxin type A plus therapy being cost-effective at the threshold value did not exceed 0.39, regardless of the assumptions made

Cascaded- and Modular-Multilevel Converter Laboratory Test System Options: A Review

The increasing importance of cascaded multilevel converters (CMCs), and the sub-category of modular multilevel converters (MMCs), is illustrated by their wide use in high voltage DC connections and in static compensators. Research is being undertaken into the use of these complex pieces of hardware and software for a variety of grid support services, on top of fundamental frequency power injection, requiring improved control for non-traditional duties. To validate these results, small-scale laboratory hardware prototypes are often required. Such systems have been built by many research teams around the globe and are also increasingly commercially available. Few publications go into detail on the construction options for prototype CMCs, and there is a lack of information on both design considerations and lessons learned from the build process, which will hinder research and the best application of these important units. This paper reviews options, gives key examples from leading research teams, and summarizes knowledge gained in the development of test rigs to clarify design considerations when constructing laboratory-scale CMCs.This work was supported in part by The University of Manchester supported by the National Innovation Allowance project ``VSC-HVDC Model Validation and Improvement'' and Dr. Heath's iCASE Ph.D. studentship supported through Engineering and Physical Sciences Research Council (EPSRC) and National Grid, in part by the Imperial College London supported by EPSRC through the HubNet Extension under Grant EP/N030028/1, in part by an iCASE Ph.D. Studentship supported by EPSRC and EDF Energy and the CDT in Future Power Networks under Grant EP/L015471/1, in part by University of New South Wales (UNSW) supported by the Solar Flagships Program through the Education Infrastructure Fund (EIF), in part by the Australian Research Council through the Discovery Early Career Research Award under Grant DECRA_DE170100370, in part by the Basque Government through the project HVDC-LINK3 under Grant ELKARTEK KK-2017/00083, in part by the L2EP research group at the University of Lille supported by the French TSO (RTE), and in part by the Hauts-de-France region of France with the European Regional Development Fund under Grant FEDER 17007725

CBT repackaged or a novel treatment? The Lightning Process compared with UK specialist medical care for paediatric Chronic Fatigue Syndrome

Methods: Theoretical comparison including stakeholder consultation. Rationale: UK specialist medical care (SMC) for paediatric Chronic Fatigue Syndrome (CFS/ME) includes behavioural approaches (Graded Exercise Therapy; Activity Management) and Cognitive Behavioural Therapy for fatigue (CBT-F). Treatment is suboptimal with a third of children not recovering after 6 months of SMC. Many families seek alternative treatments at personal cost, including the Lightning Process (LP). Evidence shows LP can improve patient outcomes, though this intervention is not widely known/understood. Objectives: To describe LP in comparison with SMC approaches in order to identify distinct elements, inform clinicians about treatment options, and generate hypotheses around effectiveness. Results: While overlaps with SMC approaches were identified, and CBT-F in particular, distinct elements of LP were its focus on language style, neurophysiological rationale, affective/physiological change technique and mode of delivery. Conclusion: This theoretical comparison identified distinct elements of LP which could be explored in future interventions or research aiming to improve clinical outcomes for children with CFS/ME, and informs clinicians about treatment options available for families

ALMA Resolves the Nuclear Disks of Arp 220

We present 90 mas (37 pc) resolution ALMA imaging of Arp 220 in the CO (1-0) line and continuum at λ =2.6 mm. The internal gas distribution and kinematics of both galactic nuclei are well resolved for the first time. In the west nucleus, the major gas and dust emission extends out to 0[fraction of arcsecond symbol]2 radius (74 pc); the central resolution element shows a strong peak in the dust emission but a factor of 3 dip in the CO line emission. In this nucleus, the dust is apparently optically thick (τ [subscript 2.6mm ~ 1]) at λ = 2.6mm with a dust brightness temperature of ~147 K. The column of interstellar matter at this nucleus is N[subscript H2] ≥ 2 x 10 [superscript 26] cm[superscript −2], corresponding to ~900 gr cm[superscript −2]. The east nucleus is more elongated with radial extent 0[fraction of arcsecond symbol]3 or ~111 pc. The derived kinematics of the nuclear disks provide a good fit to the line profiles, yielding the emissivity distributions, the rotation curves, and velocity dispersions. In the west nucleus, there is evidence of a central Keplerian component requiring a central mass of 8 × 10[superscript 8]M [subscript ⊙]. The intrinsic widths of the emission lines are a Δν(FWHM})=250 (west) and 120 (east) km s[superscript −1]. Given the very short dissipation timescales for turbulence (≤ [superscript 5] years), we suggest that the line widths may be due to semicoherent motions within the nuclear disks. The symmetry of the nuclear disk structures is impressive, implying the merger timescale is significantly longer than the rotation period of the disks

The Maia detector array and x-ray fluorescence imaging system: Locating rare precious metal phases in complex samples

X-ray fluorescence images acquired using the Maia large solid-angle detector array and integrated real-time processor on the X-ray Fluorescence Microscopy (XFM) beamline at the Australian Synchrotron capture fine detail in complex natural samples with images beyond 100M pixels. Quantitative methods permit real-time display of deconvoluted element images and for the acquisition of large area XFM images and 3D datasets for fluorescence tomography and chemical state (XANES) imaging. This paper outlines the Maia system and analytical methods and describes the use of the large detector array, with a wide range of X-ray take-off angles, to provide sensitivity to the depth of features, which is used to provide an imaging depth contrast and to determine the depth of rare precious metal particles in complex geological samples. © 2013 SPIE

Identifying Dominant Recombination Mechanisms in Perovskite Solar Cells by Measuring the Transient Ideality Factor

The light ideality factor determined by measuring the open-circuit voltage (V) as a function of light intensity is often used to identify the dominant recombination mechanism in solar cells. Applying this “Suns-V” technique to perovskite cells is problematic since the V evolves with time in a way that depends on the previously applied bias (V), bias light intensity, device architecture and processing route. Here, we show that the dominant recombination mechanism in two structurally similar CH3NH3PbI3 devices containing either mesoporous Al2O3 or TiO2 layers can be identified from the signature of the transient ideality factor following application of a forward bias, V, to the device in the dark. The transient ideality factor is measured by monitoring the evolution of V as a function of time at different light intensities. The initial values of ideality found using this technique are consistent with estimates of the ideality factor obtained from measurements of photoluminescence vs light intensity and electroluminescence vs current density. Time-dependent simulations of the measurement on modeled devices, which include the effects of mobile ionic charge, reveal that this initial value can be correlated to an existing zero-dimensional model while steady-state values must be analyzed taking into account the homogeneity of carrier populations throughout the absorber layer. The analysis shows that Shockley-Read-Hall (SRH) recombination through deep traps at the charge-collection interfaces is dominant in both architectures of measured device. Using transient photovoltage measurements directly following illumination on bifacial devices, we further show that the perovskite–electron-transport-layer interface extends throughout the mesoporous TiO2 layer, consistent with a transient ideality signature corresponding to SRH recombination in the bulk of the film. This method will be useful for identifying performance bottlenecks in alternative variants of perovskite and other mixed ionic-electronic conducting absorber-based solar cells