Reviews

P. Race, 500 Tips on Group Learning, London: Kogan Page, 2000. ISBN: 0–7494–2884–8. Softback, vii + 135 pages, £15.99

Leveraging the Supply Chain: An Assessment of Supply Chain Partners\u27 Influence on Organizational Performance

The supply chain is recognized as an integral part of the value creation process and a critical driver of performance. Indeed, a supply chain relationship grants buyers and suppliers the opportunity to share in the value generated by their partners, access partner capabilities and resources to enact their own strategic initiatives, and jointly generate value above what each firm could produce in isolation. The purpose of this dissertation is to investigate how firms can leverage the supply chain to attain superior organizational performance. Specifically, three essays, each focused on a distinct organizational process, explore how supply chain partners influence a firm’s financial performance. Essay 1 focuses on inventory management and the effect of supplier inventory leanness on a firm’s financial performance. Essay 2 focuses on organizational governance and the potential value and risk of inviting an executive from a supplier or customer firm to serve on the board of directors. Essay 3 integrates supply chain and competitive dynamics research to explore the influence of supplier competitive actions on a firm’s financial performance. Each essay covers a distinct area in which supply chain partners can act as a source of advantage and enable superior organizational performance. Firms do not operate in isolation, and a failure to consider supply chain partners when developing and implementing firm operations and strategies is an opportunity lost. This dissertation, thus, contributes to extant supply chain research by expanding research on supply chain partners’ influence on performance outcomes. The findings have major implications to managerial decision-making on sourcing, strategic management, and supply chain design. Collectively, this dissertation identifies additional avenues for firms to leverage the supply chain and, in turn, achieve superior organizational performance

Reviews

Danny Saunders and Nina Smalley (eds.), The International Simulation and Gaming Research Yearbook — Volume 8: Simulations and Games for Transition and Change, London: Kogan Page, 2000. ISBN: 0–7494–3397–3. Hardback, viii+271 pages, £40.00

Starting a Streaming Video Program on a Limited Budget

Streaming videos are a desirable supplement to physical DVDs, but academic libraries may feel intimidated by the cost of adding another format to their collections. However, streaming videos can be surprisingly affordable. In the midst of a budget crunch, the librarians at Western Carolina University were able to start a streaming video program, first by selecting titles à la carte, and later by launching two streaming services, Kanopy (using a demand-driven acquisitions model) and Swank (using a mediated acquisitions model). These streaming videos allow for unlimited simultaneous access by local users as well as distance-education students, and they come with performance rights that help teaching faculty prevent copyright infringement. Despite some limitations with streaming videos, the format has been well received by faculty, students, and staff

The feasibility of a flexible exercise participation programme (FEPP) for individuals with multiple sclerosis

Background and purpose Individuals with multiple sclerosis (MS) want health advice regarding participation in their choice of exercise. To address this need, a flexible exercise participation programme (FEPP) was developed, underpinned by the MS aerobic exercise guidelines and supported by a physiotherapist using behaviour change techniques. The aim of this study was to investigate the feasibility of the FEPP for individuals with minimal disability from MS. Methods A feasibility study utilising a single group pre/post-intervention design was conducted. The 12-week FEPP was completed by 10 individuals with MS (EDSS 0–3.5). Exercise progression in duration, intensity or frequency of exercise (in line with MS exercise guidelines) was guided by a self-perceived weekly energy level score, and weekly telephone coaching sessions using behavioural change techniques. Trial feasibility was assessed via measures of process (recruitment and retention), resources/management (communication time; data entry) and scientific feasibility (safety; compliance). Secondary FEPP feasibility outcomes included the Goal Attainment Scale (GAS) T-score, exercise participation (weekly exercise diary), high-level mobility (HiMAT), vitality (Subjective Vitality Scale), biomarkers for inflammation (cytokines levels [IL2, IL4, IL6, IL10, TNF and IFNγ]), and acceptability (participant survey). Results Process: In total, 11 (85%) of 13 eligible participants enroled at baseline with 10 (91%) completing the study. Resources/management: Coaching sessions included a baseline interview—mean 39 min (SD: 6.6) and telephone coaching—mean 10 min (SD: 3.8) per week. Outcome measure data collection time—mean 44 min (SD: 2.1). Scientific feasibility: Two participants experienced a fall during their exercise participation. Self-reported compliance was high (99%). GAS T-scores increased significantly, indicating achievement of exercise participation goals. Secondary outcomes showed trends towards improvement. Discussion The FEPP was feasible, safe and highly acceptable for use with individuals with MS and warrants a larger trial to explore effectiveness

TreeVector: Scalable, Interactive, Phylogenetic Trees for the Web

Background: Phylogenetic trees are complex data forms that need to be graphically displayed to be human-readable. Traditional techniques of plotting phylogenetic trees focus on rendering a single static image, but increases in the production of biological data and large-scale analyses demand scalable, browsable, and interactive trees. Methodology/Principal Findings: We introduce TreeVector, a Scalable Vector Graphics–and Java-based method that allows trees to be integrated and viewed seamlessly in standard web browsers with no extra software required, and can be modified and linked using standard web technologies. There are now many bioinformatics servers and databases with a range of dynamic processes and updates to cope with the increasing volume of data. TreeVector is designed as a framework to integrate with these processes and produce user-customized phylogenies automatically. We also address the strengths of phylogenetic trees as part of a linked-in browsing process rather than an end graphic for print. Conclusions/Significance: TreeVector is fast and easy to use and is available to download precompiled, but is also open source. It can also be run from the web server listed below or the user’s own web server. It has already been deployed o

Evolution of a Complex Locus: Exon Gain, Loss and Divergence at the Gr39a Locus in Drosophila

Background. Gene families typically evolve by gene duplication followed by the adoption of new or altered gene functions. A different way to evolve new but related functions is alternative splicing of existing exons of a complex gene. The chemosensory gene families of animals are characterised by numerous loci of related function. Alternative splicing has only rarely been reported in chemosensory loci, for example in 5 out of around 120 loci in Drosophila melanogaster. The gustatory receptor gene Gr39a has four large exons that are alternatively spliced with three small conserved exons. Recently the genome sequences of eleven additional species of Drosophila have become available allowing us to examine variation in the structure of the Gr39a locus across a wide phylogenetic range of fly species. Methodology/Principal Findings. We describe a fifth exon and show that the locus has a complex evolutionary history with several duplications, pseudogenisations and losses of exons. PAML analyses suggested that the whole gene has a history of purifying selection, although this was less strong in exons which underwent duplication. Conclusions/Significance. Estimates of functional divergence between exons were similar in magnitude to functional divergence between duplicated genes, suggesting that exon divergence is broadly equivalent to gene duplication.Publisher PDFPeer reviewe

The determination of planetary structure in tidally relaxed inclined systems

[Abridged] The recent discovery of a transiting planet on a non-circular orbit with a massive highly eccentric companion orbiting HAT-P-13 offers the possibility of probing the structure of the short-period planet. The ability to do this relies on the system being in a quasi-equilibrium state in the sense that the eccentricities are constant on the usual secular timescale, and decay on a timescale which is much longer than the age of the system. Since the equilibrium eccentricity is effectively a function only of observable system parameters and the unknown Love number of the short-period planet, the latter can be determined with accurate measurements of the planet's eccentricity and radius. However, this analysis relies on the unlikely assumption that the system is coplanar. Here we generalize our recent analysis of this fixed-point phenomenon to mutually inclined systems and show that the fixed point of coplanar systems is replaced by a limit cycle, with the average value of the eccentricity decreasing and its amplitude of variation increasing with increasing mutual inclination. This behaviour significantly reduces the ability to unambiguously determine the Love number of the short-period planet if the mutual inclination is higher than around 10^o. We show that for Q-values less than 10^6, the HAT-P-13 system cannot have a mutual inclination between 54 and 126^o because Kozai oscillations coupled with tidal dissipation would act to quickly move the inclination outside this range, and that the behaviour of retrograde systems is the mirror image of that for prograde systems. We derive a relationship between the equilibrium radius of the short-period planet, its Q-value and its core mass, and show that given current estimates of e_b and the planet radius, the HAT-P-13 system is likely to be close to coplanar [...]Comment: 24 pages, 14 figures, Accepted for publication in MNRAS. **NOTE REFINED PREDICTION FOR MUTUAL INCLINATIO

Epidemiological information in sheep health management

We use epidemiology whenever we consider the management of sheep health. To measure a disease, we need a precise and unique case definition and we often use diagnostic tests to assist in defining a disease. Diagnostic tests are not always accurate. Thus, it is necessary to consider the decisions that will be taken, based on the result of testing, in order to decide the most useful approach to interpret a test based on its test sensitivity and specificity and the prevalence of the disease in a flock. This is particularly important when decisions on culling or selection of sheep to attain, e.g. freedom from disease, are made on the basis of test results. Infectious diseases spread within and between flocks in a variety of ways; brought-in sheep are the most likely source for introduction of a new pathogen or strain of a pathogen. When a pathogen enters a naïve flock, it spreads through susceptible sheep and persists in the flock, whilst there are susceptible sheep that can be infected. Pathogens use a variety of techniques to persist, including changes in the pathogen itself, alterations in infected hosts enabling them to remain infectious for prolonged periods or to be re-infected, persistence in other host species or in the environment. We need to consider these strategies to decide whether elimination or control of a particular pathogen is more likely to be effective. Whatever the flock control strategy, treatment of diseased individuals is essential for their welfare and can also protect the rest of the flock, if treatment reduces the infectious period. Decisions on management of disease are based on our knowledge of the flock and its management and the evidence base for various control strategies. There are now formal techniques for evaluating the evidence base that can assist in evaluating evidence. One area where we need to evaluate evidence is on cause. It is not possible to prove anything, but we can use the weight of evidence to evaluate likely cause. There are nine aspects of association with which we can evaluate a piece of evidence; these are: strength, consistency, specificity, temporality, dose–response, plausibility, coherence, experiment and analogy

Elastic Resistance Effectiveness on Increasing Strength of Shoulders and Hips

Elastic resistance is a common training method used to gain strength. Currently, progression with elastic resistance is based on the perceived exertion of the exercise or completion of targeted repetitions; exact resistance is typically unknown. This study\u27s objective is to determine if knowledge of load during elastic resistance exercise will increase strength gains during exercises. Participants were randomized into two strength training groups, elastic resistance only and elastic resistance using a load cell (LC) that displays force during exercise. The LC group used a Smart Handle (Patterson Medical Supply, Chicago, IL) to complete all exercises. Each participant completed the same exercises three times weekly for 8 weeks. The LC group was provided with a set load for exercises whereas the elastic resistance only group was not. Participant\u27s strength was tested at baseline and program completion, measuring isometric strength for shoulder abduction (SAb), shoulder external rotation (SER), hip abduction (HAb), and hip extension (HEx). Independent t-tests were used to compare the normalized torques between groups. No significant differences were found between groups. Shoulder strength gains did not differ between groups (SAb p\u3e0.05; SER p\u3e0.05). Hip strength gains did not differ between groups (HAb p\u3e0.05; HEx p\u3e0.05). Both groups increased strength due to individual supervision, constantly evaluating degree of difficulty associated with exercise and providing feedback while using elastic resistance. Using a LC is as effective as supervised training and could provide value in a clinic setting when patients are working unsupervised