199 research outputs found

    Los productos forestales no maderables como complemento económico en zonas forestales de países en desarrollo. Caso de El Merendón, en San Pedro Sula. Honduras. CA.

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    Se analizan las posibilidades que tiene el cultivo de mariposas y la utilización de las plantas en la alimentación, sanidad y otros usos en el medio rural de Honduras, como complemento para su desarrollo

    Desarrollo, globalización y economía sostenible

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    El presente trabajo de Fin de Máster se centra en el desarrollo y elaboración de una unidad didáctica para la asignatura de economía de primero de Bachillerato. Inicialmente, se han detallado todos los puntos que debe contener una programación didáctica y que sirven como base de la unidad didáctica elaborada. Para concluir, se detallan de forma pormenorizada la metodología, recursos, contenidos y actividades de la unidad didáctica cuyo nombre es "Desarrollo, globalización y economía sostenible".Departamento de Economía AplicadaMáster en Profesor de Educación Secundaria Obligatoria y Bachillerato, Formación Profesional y Enseñanzas de Idiomas (Especialidad: Economía

    Centralized workflow process for multilanguage subtitling of live events

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    Descripción de una plataforma de servicios basados en cloud para la generación de subtítulos y su traducción a diversas lenguas y tecnologías como Broadcast TV o WebTV para sordos

    Young people, privacy and dependence on social networks

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    En los últimos años asistimos a una cierta consolidación de los comportamientos y actitudes aparejados al uso de las redes sociales y de las obligaciones tecnológicas que los usuarios se han autoimpuesto: la inversión de tiempo y energías en compartir con los demás escenas y actos de su vida privada y profesional, la necesidad de estar siempre conectados, y la agudización de sensaciones y sentimientos contrapuestos que todo ello provoca (ansiedad, inseguridad, soledad…). Es esta comunicación se describe de manera pormenorizada el comportamiento, las actitudes y la percepción sobre las redes sociales que manifiestan los jóvenes relativas a la privacidad y la dependencia en estas redes. En el caso de la privacidad51, los jóvenes son cada vez más conscientes de que, a pesar de que manifiestan una dependencia que roza la adicción, deben proteger parte de su vida privada porque lo que se expone en las redes resulta después incontrolable. Los resultados sobre privacidad y dependencia en las redes que presentamos aquí forman parte de la investigación que se realiza en el Programa de Actividades sobre Vulnerabilidad Digital (PROVULDIG) cuyo objetivo principal es estudiar las amenazas y retos que Internet representa para diversos colectivos sociales especialmente vulnerables, como son los niños, los adolescentes, los jóvenes y las tercera edad. Con ello se pretende también dar a conocer las posibilidades de alfabetización digital de los jóvenes y servir como marco de referencia tanto para sus progenitores como para todos aquellos sectores de la sociedad que trabajan con este colectivo, especialmente el profesorado, que se encuentran con grandes lagunas a la hora de proponer nuevas vías de formación, trabajo y participación online de manera constructiva. El objetivo es ofrecer un panorama descriptivo de la situación actual que a su vez pueda servir para orientar a los ciudadanos hacia una participación responsable en las redes sociales con pleno conocimiento de sus posibilidades y sus límites.In recent years, we have observed certain consolidation of behaviors and attitudes associated to the use of social networks and the technological obligations that some users have self-imposed to themselves: the investment of time and energy in sharing with other scenes and acts of their private and professional lives, the need to be always connected, and the intensification of the conflicting feelings that all this provokes (anxiety, insecurity, loneliness...). This communication describes in detail the behavior, attitudes and perception about social networks that young people manifest regarding privacy and dependence on these networks. For example, in the case of privacy, young people are increasingly aware that, despite their dependence or addiction, they must protect part of their private life because what is today exposed on a social network is later uncontrollable. The results on privacy and dependence on social networks presented here are part of a research project within the Program of Activities on Digital Vulnerability (PROVULDIG), whose main objective is to study the threats and challenges that the Internet represents for various social groups especially vulnerable, such as children, adolescents, and the elderly. It also aims at increasing the awareness about the possibilities of digital literacy of young people and serves as a framework of reference for both their parents and the sectors of society that work with this group --especially teachers--, who find large gaps when proposing new ways of training, work and online participation in a constructive way The objective is to offer a descriptive overview of the current situation that can serve to guide citizens towards responsible participation in social networks with full knowledge of its possibilities and its limits

    Extraction of Anthocyanins and Total Phenolic Compounds from Açai (Euterpe oleracea Mart.) Using an Experimental Design Methodology. Part 3: Microwave-Assisted Extraction

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    In this work, two methods based on microwave-assisted extraction techniques for the extraction of both anthocyanins and total phenolic compounds from acai have been developed. For that, a full factorial design (Box-Behnken design) has been used to optimize the following four variables: solvent composition (25-75% methanol in water), temperature (50-100 degrees C), pH (2-7), and sample/solvent ratio (0.5 g: 10 mL-0.5 g: 20 mL). The anthocyanins and total phenolic compounds content have been determined by ultra high-pressure liquid chromatography and Folin-Ciocalteu method, respectively. The optimum conditions for the extraction of anthocyanins were 38% MeOH in water, 99.63 degrees C, pH 3.00, at 0.5 g: 10 mL of ratio, while for the extraction of total phenolic compounds they were 74.16% MeOH in water, 99.14 degrees C, pH 5.46, at 0.5 g: 20 mL of ratio. Both methods have shown a high repeatability and intermediate precision with a relative standard deviation lower than 5%. Furthermore, an extraction kinetics study was carried out using extraction periods ranging from 2 min until 25 min. The optimized methods have been applied to acai-containing real samples. The results with such real samples have confirmed that both methods are suitable for a rapid and reliable extraction of anthocyanins and total phenolic compounds

    Extraction of anthocyanins and total phenolic compounds from açai (euterpe oleracea mart.) using an experimental design methodology. part 1: Pressurized liquid extraction

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    Currently, açai is one of the most important fruits present in the world. Several studies have demonstrated its high content in phenolic compounds and anthocyanins. Both of them are responsible of interesting properties of the fruit such as anti-inflammatory, antioxidant or anticancer. In the present study, two optimized pressurized liquid extraction (PLE) methods have been developed for the extraction of anthocyanins and total phenolic compounds from açai. A full factorial design (Box-Behnken design) with six variables (solvent composition (25%-75% methanol-in-water), temperature (50-100°C), pressure (100-200 atm), purge time (30-90 s), pH (2-7) and flushing (50%-150%)) were employed. The percentage of methanol in the extraction solvent was proven to be the most significant variable for the extraction of anthocyanins. In the case of total phenolic compounds, the extraction temperature was the most influential variable. The developed methods showed high precision, with relative standard deviations (RSD) of less than 5%. The applicability of the methods was successfully evaluated in real samples. In conclusion, two rapid and reliable PLE extraction methods to be used for laboratories and industries to determine anthocyanins and total phenolic compounds in açai and its derived products were developed in this work

    Extraction of Anthocyanins and Total Phenolic Compounds from Acai (Euterpe oleracea Mart.) Using an Experimental Design Methodology. Part 2: Ultrasound-Assisted Extraction

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    Two optimized methods for ultrasound-assisted extraction were evaluated for the extraction of two types of acai bioactive compounds: Total anthocyanins (TAs) and total phenolic compounds (TPCs). For the extraction optimization, a Box Behnken factorial design of different variables in the following intervals was used: Methanol-water (25%-75%) for solvent composition, temperatures between 10 and 70 degrees C, amplitude in the range between 30% and 70% of the maximum amplitude -200 W), extraction solvent pH (2-7), the ratio for sample-solvent (0.5 g:10 mL-0.5 g:20 mL), and cycle between 0.2 and 0.7 s. The extraction kinetics were studied using different periods between 5 and 30 min. TA and TPC were analyzed by UHPLC and the Folin-Ciocalteu method, respectively. Optimized conditions for TA were: 51% MeOH in water, 31 degrees C temperature, pH 6.38, cycle 0.7 s, 65% amplitude, and 0.5 g:10 mL of sample-solvent ratio. Optimized conditions for the TPC were: 49% MeOH in water, 41 degrees C temperature, pH 6.98, cycle 0.2 s, 30% amplitude, and 0.5 g:10 mL of sample-solvent ratio. Both methods presented a relative standard deviation below 5% in the precision study. The suitability of the methods was tested in real samples. It was confirmed that these methods are feasible for the extraction of the studied bioactive compounds from different acai matrices

    Selective C-13-Labels on Repeating Glycan Oligomers to Reveal Protein Binding Epitopes through NMR: Polylactosamine Binding to Galectins

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    A combined chemo-enzymatic synthesis/NMR-based methodology is presented to identify, in unambiguous manner, the distinctive binding epitope within repeating sugar oligomers when binding to protein receptors. The concept is based on the incorporation of C-13-labels at specific monosaccharide units, selected within a repeating glycan oligomeric structure. No new chemical tags are added, and thus the chemical entity remains the same, while the presence of the C-13-labeled monosaccharide breaks the NMR chemical shift degeneracy that occurs in the non-labeled compound and allows the unique identification of the different components of the oligomer. The approach is demonstrated by a proof-of-concept study dealing with the interaction of a polylactosamine hexasaccharide with five different galectins that display distinct preferences for these entities.This research was funded by European Research Council for financial support (ERC-2017-AdG, project number 788143-RECGLYCANMR). We also thank Agencia Estatal de Investigacion (Spain) for project RTI2018-094751-B-C21 and the Severo Ochoa Excellence Accreditation (SEV-2016-0644

    Selective C-13-Labels on Repeating Glycan Oligomers to Reveal Protein Binding Epitopes through NMR: Polylactosamine Binding to Galectins

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    A combined chemo-enzymatic synthesis/NMR-based methodology is presented to identify, in unambiguous manner, the distinctive binding epitope within repeating sugar oligomers when binding to protein receptors. The concept is based on the incorporation of C-13-labels at specific monosaccharide units, selected within a repeating glycan oligomeric structure. No new chemical tags are added, and thus the chemical entity remains the same, while the presence of the C-13-labeled monosaccharide breaks the NMR chemical shift degeneracy that occurs in the non-labeled compound and allows the unique identification of the different components of the oligomer. The approach is demonstrated by a proof-of-concept study dealing with the interaction of a polylactosamine hexasaccharide with five different galectins that display distinct preferences for these entities.This research was funded by European Research Council for financial support (ERC-2017-AdG, project number 788143-RECGLYCANMR). We also thank Agencia Estatal de Investigacion (Spain) for project RTI2018-094751-B-C21 and the Severo Ochoa Excellence Accreditation (SEV-2016-0644
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