Magnetic storm time effect on upper and lower atmosphere: An analysis through GPS and remote sensing observation over Guwahati

The role of solar geomagnetic factors on the upper atmosphere is though well studied, their effects at the lower atmosphere are yet to be understood. The paper is an attempt to examine association if any between ionospheric variabilities and lower atmospheric parameters at different solar geomagnetic ambiances. For this purpose total electron content (TEC) data collected at Gauhati University (26°10' N, 91°45' E) from GPS observation and temperature and wind data received from Radiosonde and satellite data are utilized. The study carried out for Low, Medium and High solar activity conditions. The result shows strong association of positive and negative ionospheric effects on tropopause temperature during strong geomagnetic storm situation in high solar ambiances. The possible causes especially related to appleton anomaly crest zone are highlighted

Effective augmentation of complex networks

Networks science plays an enormous role in many aspects of modern society from distributing electrical power across nations to spreading information and social networking amongst global populations. While modern networks constantly change in size, few studies have sought methods for the difficult task of optimising this growth. Here we study theoretical requirements for augmenting networks by adding source or sink nodes, without requiring additional driver-nodes to accommodate the change i.e., conserving structural controllability. Our "effective augmentation" algorithm takes advantage of clusters intrinsic to the network topology, and permits rapidly and efficient augmentation of a large number of nodes in one time-step. "Effective augmentation" is shown to work successfully on a wide range of model and real networks. The method has numerous applications (e.g. study of biological, social, power and technological networks) and potentially of significant practical and economic value

Alliance of Genome Resources Portal: unified model organism research platform

The Alliance of Genome Resources (Alliance) is a consortium of the major model organism databases and the Gene Ontology that is guided by the vision of facilitating exploration of related genes in human and well-studied model organisms by providing a highly integrated and comprehensive platform that enables researchers to leverage the extensive body of genetic and genomic studies in these organisms. Initiated in 2016, the Alliance is building a central portal (www.alliancegenome.org) for access to data for the primary model organisms along with gene ontology data and human data. All data types represented in the Alliance portal (e.g. genomic data and phenotype descriptions) have common data models and workflows for curation. All data are open and freely available via a variety of mechanisms. Long-term plans for the Alliance project include a focus on coverage of additional model organisms including those without dedicated curation communities, and the inclusion of new data types with a particular focus on providing data and tools for the non-model-organism researcher that support enhanced discovery about human health and disease. Here we review current progress and present immediate plans for this new bioinformatics resource

Alliance of Genome Resources Portal: unified model organism research platform

The Alliance of Genome Resources (Alliance) is a consortium of the major model organism databases and the Gene Ontology that is guided by the vision of facilitating exploration of related genes in human and well-studied model organisms by providing a highly integrated and comprehensive platform that enables researchers to leverage the extensive body of genetic and genomic studies in these organisms. Initiated in 2016, the Alliance is building a central portal (www.alliancegenome.org) for access to data for the primary model organisms along with gene ontology data and human data. All data types represented in the Alliance portal (e.g. genomic data and phenotype descriptions) have common data models and workflows for curation. All data are open and freely available via a variety of mechanisms. Long-term plans for the Alliance project include a focus on coverage of additional model organisms including those without dedicated curation communities, and the inclusion of new data types with a particular focus on providing data and tools for the non-model-organism researcher that support enhanced discovery about human health and disease. Here we review current progress and present immediate plans for this new bioinformatics resource

Cerebrospinal fluid markers of neuroinflammation in delirium:A role for interleukin-1β in delirium after hip fracture

AbstractObjectiveExaggerated central nervous system (CNS) inflammatory responses to peripheral stressors may be implicated in delirium. This study hypothesised that the IL-1β family is involved in delirium, predicting increased levels of interleukin-1β (IL-1β) and decreased IL-1 receptor antagonist (IL-1ra) in the cerebrospinal fluid (CSF) of elderly patients with acute hip fracture. We also hypothesised that Glial Fibrillary Acidic Protein (GFAP) and interferon-γ (IFN-γ) would be increased, and insulin-like growth factor 1 (IGF-1) would be decreased.MethodsParticipants with acute hip fracture aged >60 (N=43) were assessed for delirium before and 3–4 days after surgery. CSF samples were taken at induction of spinal anaesthesia. Enzyme-linked immunosorbent assays (ELISA) were used for protein concentrations.ResultsPrevalent delirium was diagnosed in eight patients and incident delirium in 17 patients. CSF IL-1β was higher in patients with incident delirium compared to never delirium (incident delirium 1.74pg/ml (1.02–1.74) vs. prevalent 0.84pg/ml (0.49–1.57) vs. never 0.66pg/ml (0–1.02), Kruskal–Wallis p=0.03). CSF:serum IL-1β ratios were higher in delirious than non-delirious patients. CSF IL-1ra was higher in prevalent delirium compared to incident delirium (prevalent delirium 70.75pg/ml (65.63–73.01) vs. incident 31.06pg/ml (28.12–35.15) vs. never 33.98pg/ml (28.71–43.28), Kruskal–Wallis p=0.04). GFAP was not increased in delirium. IFN-γ and IGF-1 were below the detection limit in CSF.ConclusionThis study provides novel evidence of CNS inflammation involving the IL-1β family in delirium and suggests a rise in CSF IL-1β early in delirium pathogenesis. Future larger CSF studies should examine the role of CNS inflammation in delirium and its sequelae

Sciences and fiction in the Romance literatures

Les auteurs qui ont contribué à la création de ce volume collectif proposent une réflexion sur la présence, latente ou patente, des différents savoirs dans la fiction littéraire, depuis le Moyen Âge jusqu’à l’époque post-moderne. La médecine, les sciences (pures, expérimentales, occultes...), le savoir technique, l’investigation du temps et de l’espace entretiennent, comme l'écrit Barbara Sosień dans son Introduction, « des parentés, des affinités, des intersections et des liaisons, parfois piégées, souvent dangereuses » avec la fiction littéraraire. De l’autre côté, « la littérature et les arts, poussés par des mystérieux apriorismes, formulent des questions auxquelles, tôt ou tard, la science trouve des réponses ». Les vingt quatre études examinent des cas particuliers de ces relations dans les œuvres canoniques (mais aussi dans celles plus obscures) de la littérature française, espagnole, francophone, arabe... en laissant dialoguer différentes clés de lecture et divers outils méthodologiques

Then I shall dream of pale blue horizons... : studies dedicated to Barbara Sosień

Cet ouvrage collectif, publié à l'occasion du jubilé de Madame le Professeur Barbara Sosień, spécialiste de l'imaginaire du romantisme français, réunit trente-trois études rédigées par des auteurs affiliés à différentes universités européennes. L'ensemble comporte quatre parties dont les thèmes sont suggérés par diverses connotations de la phrase de Baudelaire : Alors je rêverai des horizons bleuâtres... Le symbolisme du bleu, les thématiques du rêve, du voyage et de l'envol, présents dans des textes émanant d'époques et de cultures différentes, sont ici sondés par le biais de propositions méthodologiques individuelles. La cohérence du volume est assurée par la référence implicite aux travaux de la Dédicataire et à la perspective de l'imagination symbolique qu'elle a mise en oeuvre dans ses études, jouissant d'une grande estime auprès des spécialistes du romantisme

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This article presents the results of research and rescue excavations at the site No. 16 in Biesiadki, com. Gnojnik, located in the Wiśnicz Foothills. This region is strongly associated with the Early Neolithic settlement occupying the region between the Dunajec and Uszwica rivers. In the course of excavations, numerous ceramic and stone materials were acquired. In order to determine the chronology of the artefacts, technological, stylistic and morphological analyses were used, which allowed the researchers to assign the collected finds to the communities of the Linear Pottery culture, Malice culture and Bükk culture