A CLINICAL STUDY TO EVALUATE THE RASAYANA EFFECT OF ASTHISHRINKHALAGHRITA IN JARA

Modern medicine has made a great deal of progress in understanding the aging process and in controlling age-associated health issues. The problems of Aged were neglected by Ayurvedic science and recently there started new advancements in this branch of Ayurveda which is insufficient for the current needs. This had led to lack of active longevity with more disability and dependency. Thus, this study was taken up to evaluate the Rasayana (Anti- ageing) effect of Asthishrinkhalaghrita in Jara janya vyadhi (Diseases due to senility). Methods: In present study, 30 subjects were diagnosed with the Jara janya vyadhi, selected randomly and were given with 15 ml of Asthishrinkhalaghrita in the morning for 30 days. The data obtained were recorded, tabulated and statistically analyzed using appropriate statistical methods. Results: Study showed mild improvement in overall treatment. Though no statistically significant results were obtained, there was a good improvement for the patient in Climbing stairs, Sleep disturbance, Shwasa vridhi (Dyspnoea), Malabadhata (Constipation), Agni mandya (loss of appetite)and weight gain with p value<0.05 and Slatha sandhi (laxity of joints)and walking with p value > 0.05. Conclusion: Thus Rasayana chikitsa can improve the longevity, positive health; provide the resistance to fight against the diseases, keeping the excellence in the tissues including mental faculties

Finasteride as a model for personalized medicine

The side effects of Finasteride are currently a subject of controversy. Some studies report minor or acceptable adverse effects, which decrease after a variable period of time so that they do not necessitate terminating Finasteride administration. However, several clinical and neuro-endocrine studies show that some adverse effects persist indefinitely in the form of post-Finasteride syndrome, even after the drug cessation. This paper presents a possible explanation for these inconsistent findings. First, the study design of either informing or not informing patients prior therapy about possible adverse effects can influence the incidence and magnitude of reported adverse effects. Second, structural and information dichotomies of the brain generate four distinct neuronal networks, which are activated through specific cerebral neuromodulators and that are able to support four distinct minds within an individual body. As a conclusion, the “mind psychophysiology” and the corresponding mental impairments differ across individuals, such that not only the prediction of adverse effects should be addressed from a more individualized medical perspective, but also the therapeutic strategies could be tailored to the four distinct mental profiles described. It is a personalized approach that would be applicable to several interrelated domains of neuroscience, like psychology, psychiatry and sexuality. Finally, this perspective may represent a starting point for a more individualized understanding of mental events, perhaps even a step forward in the understanding of the mind-body problem

A STUDY ON THE MAGNITUDE OF HUMAN RESOURCE IN SUN AND RANBAXY MERGER

Sun Pharmaceutical is a trailblazer in Indian pharmaceutical sector, and one of the foremost competitors in the generic drug market sets its eye onRanbaxy. Sun pharmacy which was established in 1983 listed from 1994 has its upper hand in product development. Ranbaxy was incorporated in1973, and Daiichi Sankyo, a Japanese firm, got a controlling share from 2008. This amalgamation between Sun Pharmacy and Ranbaxy would get profitable transaction for the former. The process of the coalition was a cloak and dagger affair until April 6, 2014. Before mergers and acquisitions, a company has to create an urgency call among the employees which will result in better understanding of the whole scenario. The aspects are about how financial motives and non-financial motives play a major role in mergers. This case deals with the human resource issues and complexities faced by the two players in the same business.Keywords: Merger, Acquisition, Change management, Human resource, Employee engagement, Corporate strategy

Pengaruh Kredibilitas Merek terhadap Niat Beli dengan Mediasi Kualitas yang Dirasa Konsumen Produk Batik Jetis di Sidoarjo

The purpose of this study is to examine the effect of brand credibility on the purchase intentionmediated by consumers perceived quality of batik Jetis in Sidoarjo. This research wasconducted in Sidoarjo communities who have seen batik Jetis Sidoarjo. The data used wereprimary data obtained directly from respondents by using questionnaire. The respondentswere batik Jetiss consumers. Samples used were selected through judgment sampling techniques.One hundred forty five questionnaires were distributed to the respondents. One hundredand ten data was analyzed using SEM and processed using software AMOS 21. The resultsshowed that brand credibility has a significant influence on customers perceived quality.While customers perceived quality has no significant effect on the purchase intention.Likewise, brand credibility has no significant influence on customers purchase intention.Based on these results we can conclude that customers perceived quality does not mediatethe relationship between the credibility of the brand with the customers purchase intention

Plagiarism: Awareness, Perception and Attitude of Research scholars in Farook College, Kozhikode, Kerala, India

The study is conducted on plagiarism awareness, perception, and attitude of research scholars in Farook College. There are 101 research scholars and the whole population is selected for the study. A questionnaire tool was used for data collection. The present study describes various aspects of plagiarism such as awareness of plagiarism, perception of plagiarism, use of plagiarism detection software, satisfaction with plagiarism detection software, use of citation styles, and awareness of punishments for plagiarism. The findings reveal that most of the research scholars are much aware of plagiarism and its consequences

Predicting Clinical Outcome in Diabetics versus Nondiabetics with Acute Myocardial Infarction After Thrombolysis

Acute myocardial infarction can be considered as a potential epidemic for mankind (WHO 1982). Diabetes mellitus is one of the 6 primary risk factors identified for myocardial infarction. The aim of our study was to correlate the incidence of complications with diabetes by using ST segment resolution as a tool, thereby re-enforcing the role of incomplete ST resolution as a marker of worse clinical outcome in cases of diabetes with ST-elevated myocardialinfarction in our population

Coulomb distortion and medium corrections in nucleon-removal reactions

One-nucleon removal reactions at or above the Fermi energy are important tools to explore the single-particle structure of exotic nuclei. Experimental data must be compared with calculations to extract structure information, evaluate correlation effects in nuclei or determine reaction rates for nuclear astrophysics. However, there is insufficient knowledge to calculate accurately the cross sections for these reactions. We evaluate the contributions of the final state interaction (FSI) and of the medium modifications of the nucleon-nucleon interactions and obtain the shapes and magnitudes of momentum distributions. Such effects have been often neglected in the literature. Calculations for reactions at energies 35 - 1000 MeV/nucleon are reported and compared to published data. For consistency, the state-of-the-art eikonal method for stripping and diffraction dissociation is used. We find that the two effects are important and their relative contributions vary with the energy and with the atomic and mass number of the projectile involved. These two often neglected effects modify considerably the one-nucleon removal cross sections. As expected, the effect are largest at lower energies, around 50 MeV/nucleon and on heavy targets.Comment: 12 pages, 10 figures. Accpeted for publication in the Physical Review C. arXiv admin note: text overlap with arXiv:nucl-th/0407026 by other author

Predicting Clinical Outcome in Diabetics versus Nondiabetics with Acute Myocardial Infarction After Thrombolysis

Acute myocardial infarction can be considered as a potential epidemic for mankind (WHO 1982). Diabetes mellitus is one of the 6 primary risk factors identified for myocardial infarction. The aim of our study was to correlate the incidence of complications with diabetes by using ST segment resolution as a tool, thereby re-enforcing the role of incomplete ST resolution as a marker of worse clinical outcome in cases of diabetes with ST-elevated myocardial infarction in our populationST segment elevatio

Evaluation of the modified-ceylon copra kiln for accelerated production of ball copra

This study attempted to investigate the effect of kiln drying on the rate of formation of ball copra. Three samples containing fifty partially dried-coconuts were placed as a single layer in three compartmentalized blocks namely, Front: Blok-1, Middle: Block-2, and Rear: Block-3 in the copra bed of the modified-Ceylon copra kiln. From each of the three blocks, thirty coconuts were selected randomly for labeling and their fresh weights were recorded. The samples were subjected to intermittent drying in the kiln by thirty five firing cycles using charcoal dust as the fuel source. The temperature distribution pattern of the three blocks during the first six firing was monitored at three hourly intervals. The weight losses of individual coconuts in each block were measured after the completion of each firing. The results showed that, there was a significant (p<0.05) effect of copra bed temperature on the weight losses of the samples. The first ever ball copra formation was detected in the Block-3 after the completion of the 12th firing. The percentages of ball copra formed at the end of 35th firing were 44%, 78%, and 94%, in Block-1, Block-2, and Block-3, respectively. Analytical studies indicated that the quality indices of ball copra were comparable to those of the edible white copra