60 research outputs found
Crossing boundaries:bras, lingerie and rape myths in postcolonial urban middle-class India
With the processes of modernization, urbanization and the entry of women in the formal labour market in Indian metropolitan spaces, this paper examines how the modern middle-class womanâs sartorial choices become enmeshed in popular rape myths (false beliefs) that serve to blame her for the wearing of western clothing. The paper articulates the ways in which middle-class womenâs social realities are shaped by historical, colonial and nationalist ideologies of modernization, constructed and mediated through moral codes of dressing. By drawing upon original and contemporary empirical narratives from the urban spaces of Delhi and Mumbai, we emphasise how everyday sartorial choices, in relation to particularly the bra and lingerie, can reveal the nuanced ways in which Urban Indian Professional Women (UIPW) seek to understand, negotiate, and resist patriarchal power. Our findings shed light on conflicting and contradictory spatial experiences, where some women internalize and negotiate moral codes of dressing, out of fear, and others who transgress are subject to sanctions. Given the paucity of scholarly literature in this area, the paper makes an important theoretical and empirical contribution with its focus on postcoloniality and everyday discursive material spaces of gendered and sexualized dress practices. It argues for the consciousness raising of everyday urban geographies of dress that reveal complicated structures of power that are often deemed hidden
Enantioselective reduction of aryl ketones using immobilized cells of Candida viswanathii
Enantioselective reduction of 1-acetonapthone to S(-)-1-(1-naphthyl) ethanol, a key intermediate for the synthesis of HMG Co-A reductase inhibitor, was successfully carried out using immobilized cells of a newly isolated carbonyl reductase producing yeast strain Candida viswanathii MTCC 5158. Calcium alginate (1.5%, w/v) gave the best immobilization efficiency. Among different organic solvents and ionic liquids tried as reaction media, isopropanol gave the best enantioselectivity with moderate conversion. The immobilized cells (100 mg/ml in 50 mM Tris buffer pH 9) showed best results at a substrate concentration of 0.2 mg/ml at 30 °C. After twelve cycles of reaction, no significant decrease in bioreduction efficiency of the immobilized cells was observed as compared to the free cells
Polymorphism in ADAM33 gene associated with asthmatics in West Bengal, India - An investigation by in-silico analysis
Introduction: Asthma is one of the common chronic polygenic inflammatory diseases. Genome wide association studies have identified ADAM33 as an asthma candidate gene. The present study investigated possible association of rs2280090 (T1), rs2280091 (T2) and rs3918396 (S1) single nucleotide polymorphisms (SNPs) of ADAM33 with aeroallergen induced asthma in West Bengal population, India. In addition, in-silico analysis was performed to find out changes in protein function. Methods: Forced expiratory volume in 1 second (FEV1)/Forced vital capacity (FVC), peak expiratory flow rate (PEFR) were assessed using spirometry in 1039 participants. Allergic sensitivity of 619 spirometry positive asthma patients was assessed by skin prick test (SPT) against 22 aeroallergens. For genotyping of T1, T2, and S1 SNPs in 540 allergic asthma patient and 420 control subjects, polymerase chain reaction-based restriction fragment length polymorphism was performed. Total Immunoglobulin-E (IgE) level was measured in both patients and controls. ADAM333 haplotype blocks were constructed using Haploview software v.4.2. Structural model of transmembrane and cytoplasmic domains of ADAM33 was generated using RaptorX. Protein-protein interaction was analysed using the STRING server. Results: Highest number of patient sensitivity was observed towards Cocos nusifera (n = 215) and Dermatophagoides farinae (n = 229). Significant difference in sensitivity was observed between child and late adult (P = 0.03), child and early adult (P = 0.02), adolescent and late adult (P = 0.02) and adolescent and early adult (P = 0.01). Genotypic frequencies differed significantly between patients and controls (P < 0.05). rs2280090 GG, rs2280091GG and AG genotype, and rs3918396 AA carried significant risk for asthma (P = 0.02, P = 0.008, P = 0.04, P = 0.01 respectively). ADAM33 T1, T2, and S1 polymorphisms were in high Linkage Disequilibrium (D = 0.98). Haplotype consisting of rs2280090G, rs2280091G and rs3918396A alleles were found significantly higher in patient population in comparison with controls (OR = 2.03). IgE level differed significantly among different genotypes for T1, T2, and S1 SNPs analysed in pair (P < 0.0001). FEV1/FVC ratio differed significantly among different genotypes for T1, T2 and S1 SNPs analysed in pair (P < 0.0001). Significant difference of FEV1/FVC was also found between GGA and AAG haplotype (P < 0.0001). In-silico analysis revealed T1 and T2 polymorphisms are located in cytoplasmic domain of ADAM33 may cause bronchial smooth muscle cell mobility and cellular hyperplasia as well as cytoskeletal remodelling by altered interaction with different cytoplasmic proteins found by string analysis. Conclusion: Present study showed significant association of T1, T2, and S1 polymorphisms of ADAM33 with aeroallergen-induced asthma in West Bengal, India. These polymorphisms may be used as prognostic markers and possible targets for therapeutics in future
Voluntarily induced vomiting â A yoga technique to enhance pulmonary functions in healthy humans
Optimization of process parameters for the production of carbonyl reductase by Candida viswanathii in a laboratory-scale fermentor
âYou have done our shameâ: interrogating shame and honour in diaspora in Jasvinder Sangheraâs Shame
Measurement of nuclear effects on production in p-Pb collisions at TeV
Inclusive Ï(2S) production is measured in p-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair = 8.16 TeV, using the ALICE detector at the CERN LHC. The production of Ï(2S) is studied at forward (2.03 < y< 3.53) and backward (â4.46 < y< â2.96) centre-of-mass rapidity and for transverse momentum p< 12 GeV/c via the decay to muon pairs. In this paper, we report the integrated as well as the y- and p-differential inclusive production cross sections. Nuclear effects on Ï(2S) production are studied via the determination of the nuclear modification factor that shows a strong suppression at both forward and backward centre-of-mass rapidities. Comparisons with corresponding results for inclusive J/Ï show a similar suppression for the two states at forward rapidity (p-going direction), but a stronger suppression for Ï(2S) at backward rapidity (Pb-going direction). As a function of p, no clear dependence of the nuclear modification factor is found. The relative size of nuclear effects on Ï(2S) production compared to J/Ï is also studied via the double ratio of production cross sections [Ï/Ï]pPb/[Ï/Ï] between p-Pb and pp collisions. The results are compared with theoretical models that include various effects related to the initial and final state of the collision system and also with previous measurements at = 5.02 TeV.[graphic not available: see fulltext]Inclusive (2S) production is measured in p-Pb collisions at the centre-of-mass energy per nucleon-nucleon pair TeV, using the ALICE detector at the CERN LHC. The production of (2S) is studied at forward () and backward () centre-of-mass rapidity and for transverse momentum 12 GeV/ via the decay to muon pairs. In this paper, we report the integrated as well as the - and -differential inclusive production cross sections. Nuclear effects on (2S) production are studied via the determination of the nuclear modification factor that shows a strong suppression at both forward and backward centre-of-mass rapidities. Comparisons with corresponding results for inclusive J/ show a similar suppression for the two states at forward rapidity (p-going direction), but a stronger suppression for (2S) at backward rapidity (Pb-going direction). As a function of , no clear dependence of the nuclear modification factor is found. The relative size of nuclear effects on (2S) production compared to J/ is also studied via the double ratio of production cross sections between p-Pb and pp collisions. The results are compared with theoretical models that include various effects related to the initial and final state of the collision system and also with previous measurements at = 5.02 TeV
J/ elliptic and triangular flow in Pb-Pb collisions at = 5.02 TeV
The inclusive J/Ï elliptic (v) and triangular (v) flow coefficients measured at forward rapidity (2.5 < y < 4) and the v measured at midrapidity (|y| < 0.9) in Pb-Pb collisions at = 5.02 TeV using the ALICE detector at the LHC are reported. The entire Pb-Pb data sample collected during Run 2 is employed, amounting to an integrated luminosity of 750 ÎŒb at forward rapidity and 93 ÎŒb at midrapidity. The results are obtained using the scalar product method and are reported as a function of transverse momentum p and collision centrality. At midrapidity, the J/Ï v is in agreement with the forward rapidity measurement. The centrality averaged results indicate a positive J/Ï v with a significance of more than 5Ï at forward rapidity in the p range 2 < p< 5 GeV/c. The forward rapidity v, v, and v/v results at low and intermediate p (p âČ 8 GeV/c) exhibit a mass hierarchy when compared to pions and D mesons, while converging into a species-independent curve at higher p. At low and intermediate p, the results could be interpreted in terms of a later thermalization of charm quarks compared to light quarks, while at high p, path-length dependent effects seem to dominate. The J/Ï v measurements are further compared to a microscopic transport model calculation. Using a simplified extension of the quark scaling approach involving both light and charm quark flow components, it is shown that the D-meson v measurements can be described based on those for charged pions and J/Ï flow
Multiplicity dependence of , K, and p production in pp collisions at TeV
International audienceThis paper presents the measurements of , , and transverse momentum () spectra as a function of charged-particle multiplicity density in protonâproton (pp) collisions at with the ALICE detector at the LHC. Such study allows us to isolate the center-of-mass energy dependence of light-flavour particle production. The measurements reported here cover a range from 0.1 to 20 and are done in the rapidity interval . The -differential particle ratios exhibit an evolution with multiplicity, similar to that observed in pp collisions at , which is qualitatively described by some of the hydrodynamical and pQCD-inspired models discussed in this paper. Furthermore, the -integrated hadron-to-pion yield ratios measured in pp collisions at two different center-of-mass energies are consistent when compared at similar multiplicities. This also extends to strange and multi-strange hadrons, suggesting that, at LHC energies, particle hadrochemistry scales with particle multiplicity the same way under different collision energies and colliding systems
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