The Influence of Host Condition on Post First Instar Development of the Bronze Birch Borer, \u3ci\u3eAgrilus Anxius\u3c/i\u3e (Coleoptera: Buprestidae)

The bronze birch borer is a contributing factor in birch dieback. It is believed that host condition has a major influence on the development of the borer. We found that the host tree\u27s apparent condition does not appear to influence post first instar development

Detection of Bronze Birch Borer Larvae and Pupae by Radiographs (Coleoptera: Buprestidae)

Bronze birch borer larvae and pupae were detected in small branches through the use of a portable X-ray unit. The optimum exposure time was 40 sec at 55 kV

An Investigation Into the Electrical Activity of Tender, Resting Paraspinal Muscles Using Surface Electromyography: A Pilot Study

Abnormal resting paraspinal muscle activity has been claimed to be responsible for changes in spinal tissue texture which are detectible by manual palpation. This pilot study investigated whether there was significant electrical activity in paraspinal musculature that was tender and that appeared to have altered tissue texture on palpation. Sixteen healthy volunteers between 18 and 35 years of age had their thoracic erector spinae mass palpated bilaterally from spinal levels T3 to T10 to identify paraspinal regions exhibiting altered tissue texture relative to the contralateral muscle mass. Surface electromyography (sEMG) was used to measure electrical activity in the muscle mass at the selected levels. No significant differences in electrical activity were observed between the tender and non-tender muscle masses, although a large difference existed in the one symptomatic subject. All muscle sites displayed EMG activity at rest, although the source of activity is not clear. A number of methodological problems with the EMG recording were encountered and are discussed. Future research is recommended using symptomatic participants

Integrated modeling tool for performance engineering of complex computer systems

This report summarizes Advanced System Technologies' accomplishments on the Phase 2 SBIR contract NAS7-995. The technical objectives of the report are: (1) to develop an evaluation version of a graphical, integrated modeling language according to the specification resulting from the Phase 2 research; and (2) to determine the degree to which the language meets its objectives by evaluating ease of use, utility of two sets of performance predictions, and the power of the language constructs. The technical approach followed to meet these objectives was to design, develop, and test an evaluation prototype of a graphical, performance prediction tool. The utility of the prototype was then evaluated by applying it to a variety of test cases found in the literature and in AST case histories. Numerous models were constructed and successfully tested. The major conclusion of this Phase 2 SBIR research and development effort is that complex, real-time computer systems can be specified in a non-procedural manner using combinations of icons, windows, menus, and dialogs. Such a specification technique provides an interface that system designers and architects find natural and easy to use. In addition, PEDESTAL's multiview approach provides system engineers with the capability to perform the trade-offs necessary to produce a design that meets timing performance requirements. Sample system designs analyzed during the development effort showed that models could be constructed in a fraction of the time required by non-visual system design capture tools

Australia and Cyberwarfare

This book explores Australia’s prospective cyber-warfare requirements and challenges. It describes the current state of planning and thinking within the Australian Defence Force with respect to Network Centric Warfare, and discusses the vulnerabilities that accompany the use by Defence of the National Information Infrastructure (NII), as well as Defence’s responsibility for the protection of the NII. It notes the multitude of agencies concerned in various ways with information security, and argues that mechanisms are required to enhance coordination between them. It also argues that Australia has been laggard with respect to the development of offensive cyber-warfare plans and capabilities. Finally, it proposes the establishment of an Australian Cyber-warfare Centre responsible for the planning and conduct of both the defensive and offensive dimensions of cyber-warfare, for developing doctrine and operational concepts, and for identifying new capability requirements. It argues that the matter is urgent in order to ensure that Australia will have the necessary capabilities for conducting technically and strategically sophisticated cyber-warfare activities by the 2020s. The Foreword has been contributed by Professor Kim C. Beazley, former Minister for Defence (1984–90), who describes it as ‘a timely book which transcends old debates on priorities for the defence of Australia or forward commitments, [and] debates about globalism and regionalism’, and as ‘an invaluable compendium’ to the current process of refining the strategic guidance for Australia’s future defence policies and capabilities

DRASTIC—INSIGHTS:querying information in a plant gene expression database

DRASTIC––Database Resource for the Analysis of Signal Transduction In Cells (http://www.drastic.org.uk/) has been created as a first step towards a data-based approach for constructing signal transduction pathways. DRASTIC is a relational database of plant expressed sequence tags and genes up- or down-regulated in response to various pathogens, chemical exposure or other treatments such as drought, salt and low temperature. More than 17700 records have been obtained from 306 treatments affecting 73 plant species from 512 peer-reviewed publications with most emphasis being placed on data from Arabidopsis thaliana. DRASTIC has been developed by the Scottish Crop Research Institute and the Abertay University and allows rapid identification of plant genes that are up- or down-regulated by multiple treatments and those that are regulated by a very limited (or perhaps a single) treatment. The INSIGHTS (INference of cell SIGnaling HypoTheseS) suite of web-based tools allows intelligent data mining and extraction of information from the DRASTIC database. Potential response pathways can be visualized and comparisons made between gene expression patterns in response to various treatments. The knowledge gained informs plant signalling pathways and systems biology investigations

An investigation into the electrical activity of tender, resting paraspinal muscles using surface electromyography: a pilot study

Abstract Abnormal resting paraspinal muscle activity has been claimed to be responsible for changes in spinal tissue texture which are detectible by manual palpation. This pilot study investigated whether there was significant electrical activity in paraspinal musculature that was tender and that appeared to have altered tissue texture on palpation. Sixteen healthy volunteers between 18 and 35 years of age had their thoracic erector spinae mass palpated bilaterally from spinal levels T3 to T10 to identify paraspinal regions exhibiting altered tissue texture relative to the contralateral muscle mass. Surface electromyography (sEMG) was used to measure electrical activity in the muscle mass at the selected levels. No significant differences in electrical activity were observed between the tender and non-tender muscle masses, although a large difference existed in the one symptomatic subject. All muscle sites displayed EMG activity at rest, although the source of activity is not clear. A number of methodological problems with the EMG recording were encountered and are discussed. Future research is recommended using symptomatic participants

Study protocol for a randomised controlled trial of invasive versus conservative management of primary spontaneous pneumothorax

INTRODUCTION: Current management of primary spontaneous pneumothorax (PSP) is variable, with little evidence from randomised controlled trials to guide treatment. Guidelines emphasise intervention in many patients, which involves chest drain insertion, hospital admission and occasionally surgery. However, there is evidence that conservative management may be effective and safe, and it may also reduce the risk of recurrence. Significant questions remain regarding the optimal initial approach to the management of PSP

Topology and Signature Changes in Braneworlds

It has been believed that topology and signature change of the universe can only happen accompanied by singularities, in classical, or instantons, in quantum, gravity. In this note, we point out however that in the braneworld context, such an event can be understood as a classical, smooth event. We supply some explicit examples of such cases, starting from the Dirac-Born-Infeld action. Topology change of the brane universe can be realised by allowing self-intersecting branes. Signature change in a braneworld is made possible in an everywhere Lorentzian bulk spacetime. In our examples, the boundary of the signature change is a curvature singularity from the brane point of view, but nevertheless that event can be described in a completely smooth manner from the bulk point of view.Comment: 26 pages, 8 figures, references and comments are added, minor revisions and a number of additional footnotes added, error corrected, minor corrections, to appear in Class. Quant. Gra

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus

Outcomes of hepatitis C virus (HCV) infection and treatment depend on viral and host genetic factors. Here we use human genome-wide genotyping arrays and new whole-genome HCV viral sequencing technologies to perform a systematic genome-to-genome study of 542 individuals who were chronically infected with HCV, predominantly genotype 3. We show that both alleles of genes encoding human leukocyte antigen molecules and genes encoding components of the interferon lambda innate immune system drive viral polymorphism. Additionally, we show that IFNL4 genotypes determine HCV viral load through a mechanism dependent on a specific amino acid residue in the HCV NS5A protein. These findings highlight the interplay between the innate immune system and the viral genome in HCV control