20 research outputs found

    A Polychaete’s Powerful Punch: Venom Gland Transcriptomics of Glycera Reveals a Complex Cocktail of Toxin Homologs

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    © The Author(s) 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. The article attached is the publisher's pdf

    Investigation of the genotoxic effects of ivermectin on human lymphocytes

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    The genotoxic effects of ivermectin, a widely used antiparasitic drug, were investigated. It was tested in various concentrations in PHA-activated human lymphocyte cultures, for the ability to induce sister chromatid exchange (SCE) and micronuclei. In doses of 0.30 mglml and higher it significantly increased the SCE frequency. No evidence about genotoxicity of ivermectin could be obtained in the micronucteus test
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