Gravitino Dark Matter and the Cosmic Lithium Abundances

Supersymmetric extensions of the standard model of particle physics assuming the gravitino to be the lightest supersymmetric particle (LSP), and with the next-to-LSP decaying to the gravitino during Big Bang nucleosynthesis, are analyzed. Particular emphasis is laid on their potential to solve the "Li7 problem", an apparent factor 2-4 overproduction of Li7 in standard Big Bang nucleosynthesis (BBN), their production of cosmologically important amounts of Li6, as well as the resulting gravitino dark matter densities in these models. The study includes several improvements compared to prior studies. Heavy gravitinos in the constrained minimal supersymmetric standard model (CMMSM) are reanalyzed, whereas light gravitinos in gauge-mediated supersymmetry breaking scenarios (GMSB) are studied for the first time. It is confirmed that decays of NLSP staus to heavy gravitinos, while producing all the dark matter, may at the same time resolve the Li7 problem. For NLSP decay times ~ 1000 sec, such scenarios also lead to cosmologically important Li6 (and possibly Be9) abundances. However, as such scenarios require heavy > 1 TeV staus they are likely not testable at the LHC. It is found that decays of NLSP staus to light gravitinos may lead to significant Li6 (and Be9) abundances, whereas NLSP neutralinos decaying into light gravitinos may solve the Li7 problem. Though both scenarios are testable at the LHC they may not lead to the production of the bulk of the dark matter. A section of the paper outlines particle properties required to significantly reduce the Li7 abundance, and/or enhance the Li6 (and possibly Be9) abundances, by the decay of an arbitrary relic particle.Comment: 13 pages (revtex), 9 figures, minor changes, submitted to PR

A 16-channel Digital TDC Chip with internal buffering and selective readout for the DIRC Cherenkov counter of the BABAR experiment

A 16-channel digital TDC chip has been built for the DIRC Cherenkov counter of the BaBar experiment at the SLAC B-factory (Stanford, USA). The binning is 0.5 ns, the conversion time 32 ns and the full-scale 32 mus. The data driven architecture integrates channel buffering and selective readout of data falling within a programmable time window. The time measuring scale is constantly locked to the phase of the (external) clock. The linearity is better than 80 ps rms. The dead time loss is less than 0.1% for incoherent random input at a rate of 100 khz on each channel. At such a rate the power dissipation is less than 100 mw. The die size is 36 mm2.Comment: Latex, 18 pages, 13 figures (14 .eps files), submitted to NIM

Direct multiple shooting and direct collocation perform similarly in biomechanical predictive simulations

Direct multiple shooting (DMS) and direct collocation (DC) are two common transcription methods for solving optimal control problems (OCP) in biomechanics and robotics. They have rarely been compared in terms of solution and speed. Through five examples of predictive simulations solved using five transcription methods and 100 initial guesses in the Bioptim software, we showed that not a single method outperformed systematically better. All methods converged to almost the same solution (cost, states, and controls) in all but one OCP, with several local minima being found in the latter. Nevertheless, DC based on fourth-order Legendre polynomials provided overall better results, especially in terms of dynamic consistency compared to DMS based on a fourth-order Runge-Kutta method. Furthermore, expressing the rigid-body constraints using inverse dynamics was usually faster than forward dynamics. DC with dynamics constraints based on inverse dynamics converged to better and less variable solutions. Consequently, we recommend starting with this transcription to solve OCPs but keep testing other methods.Comment: 19 pages, 4 figure

Protention and retention in biological systems

This paper proposes an abstract mathematical frame for describing some features of cognitive and biological time. We focus here on the so called "extended present" as a result of protentional and retentional activities (memory and anticipation). Memory, as retention, is treated in some physical theories (relaxation phenomena, which will inspire our approach), while protention (or anticipation) seems outside the scope of physics. We then suggest a simple functional representation of biological protention. This allows us to introduce the abstract notion of "biological inertia".Comment: This paper was made possible only as part of an extended collaboration with Francis Bailly (see references), a dear friend and "ma\^itre \'a penser", who contributed to the key ideas. Francis passed away in february 2008: we continue here our inspiring discussions and joint wor

Towards a first observation of magneto-electric directional anisotropy and linear birefringence in gases

In this contribution to PSAS'2010 we report on recent progress on an experiment aimed at measuring small optical directional anisotropies by frequency metrology in a high finesse ring cavity. We focus on our first experimental goal, the measurement of magneto-electric effects in gases. After a review of the expected effects in our set-up, we present the apparatus and the measurement procedure, showing that we already have the necessary sensitivity to start novel experiments.Comment: Proceedings of PSAS'2010, to be published in Canadian Journal of Physics, 2011 Ja

Deciphering the Anti-Aflatoxinogenic Properties of Eugenol Using a Large-Scale q-PCR Approach

Produced by several species of Aspergillus, Aflatoxin B1 (AFB1) is a carcinogenic mycotoxin contaminating many crops worldwide. The utilization of fungicides is currently one of the most common methods; nevertheless, their use is not environmentally or economically sound. Thus, the use of natural compounds able to block aflatoxinogenesis could represent an alternative strategy to limit food and feed contamination. For instance, eugenol, a 4-allyl-2-methoxyphenol present in many essential oils, has been identified as an anti-aflatoxin molecule. However, its precise mechanism of action has yet to be clarified. The production of AFB1 is associated with the expression of a 70 kB cluster, and not less than 21 enzymatic reactions are necessary for its production. Based on former empirical data, a molecular tool composed of 60 genes targeting 27 genes of aflatoxin B1 cluster and 33 genes encoding the main regulatory factors potentially involved in its production, was developed. We showed that AFB1 inhibition in Aspergillus flavus following eugenol addition at 0.5 mM in a Malt Extract Agar (MEA) medium resulted in a complete inhibition of the expression of all but one gene of the AFB1 biosynthesis cluster. This transcriptomic effect followed a down-regulation of the complex composed by the two internal regulatory factors, AflR and AflS. This phenomenon was also influenced by an over-expression of veA and mtfA, two genes that are directly linked to AFB1 cluster regulation