Evaluating the Validity and Reliability of Textile and Paper Fracture Characteristics in Forensic Comparative Analysis

In a comparative forensic analysis, an examiner can report that a physical fit exists between two torn or separated items when they realign in a manner unlikely to be replicated. Due to the common belief that it is unlikely that two unrelated fractured objects would match with distinctive characteristics, a physical fit represents the highest degree of association between two items. Nonetheless, despite the probative value that this evidence could have to a trier of fact, few studies have demonstrated such assumptions\u27 scientific validity and reliability. Moreover, there is a lack of consensus-based standard protocols for physical fit comparisons, making it difficult to demonstrate the basis for the features that constitute a “fit.” Since these analyses rely entirely on human judgment, they are highly subjective, which could be problematic in the absence of harmonized examination and interpretation criteria protocols. As a result, organizations like the National Institute of Justice and NIST-OSAC have identified the need for developing standardized methods and assessing potential error sources in this field. This research aims to address these gaps as applied to physical fits of textiles and paper. Here, standard criteria and prominent features for each material are defined to conduct physical fit examinations in a more reproducible manner. Additionally, a quantitative metric is used to quantify what constitutes a physical fit when conducting comparative analyses of textiles and paper, further increasing the validity and reliability of this methodology and providing a manner of assessing the weight of this evidence when presented in the courtroom. The first aim of this research involved the development of an objective and systematic method of quantifying the similarity between fractured textile samples. This was done by identifying relevant macroscopic and microscopic characteristics in the comparative analysis of a fractured textile dataset. Additionally, factors that affect the suitability of certain types of textiles for physical fit analysis were evaluated. Finally, the systematic score metric was implemented to quantify and document the quality of a physical fit and estimate error rates. The second objective of this study consisted of establishing the scientific foundations of individuality concerning the orientation of microfibers in fractured paper edges. In comparative analysis of paper, it is assumed that the microfibers deposited across the surface of paper are randomly oriented, a key feature for addressing the individuality of paper physical fits. However, this hypothesis has not been tested. This research evaluated the rarity and occurrence of microfiber alignments on fractured documents. It also quantified the comparative features of scissor-cut and hand-torn paper and the respective performance rates. Finally, the comparative analysis of textile and paper physical fits was validated through ground truth datasets and inter-examiner and intra-examiner variability studies. A ground truth blind dataset of known fits and known non-fits was created for 700 textile samples with various fiber types, weave patterns, and separation methods. Also, a set of 260 paper items, including 100 stamps and 160 office paper samples, were examined. The paper specimens contained handwritten or printed entries on two paper types and were separated by scissor-cut or hand-torn methods. This proposed research provides the criminal justice system with a valuable body of knowledge and a more objective and methodical assessment of the evidential value of physical fits of textiles, paper, and postage stamps

CAFOs, Culture, and Conflict on Sand Mountain: Framing Rights and Responsibilities in Appalachian Alabama

This paper presents a case study of controversy associated with large confined animal feed operations (CAFOs) on Sand Mountain in the northeast corner of Alabama, the tail-end of the Appalachian Mountains. We examine competing cultural frames developed by supporters and opponents of CAFOs that produce hogs. Both sides of the CAFO controversy utilize locally-specific cultural understandings of private property. Those opposed have framed their concerns both in terms of formal environmental standards of regulatory agencies and the responsibility of landowners not to engage in activities that adversely affect neighboring land owners. CAFO operators have framed the issue by drawing upon local traditions of individual rights over how one uses land, while calling upon reciprocal social relationships that stretch across multiple generations to win support or mute opposition. The controversy has spilled over into the legislative and regulatory arenas, where tradition-based cultural frames are repeated but in different forms

A trade space model for robotic lunar exploration

Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Aeronautics and Astronautics, 2010.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Cataloged from student submitted PDF version of thesis.Includes bibliographical references (p. 147-152).The last decade has seen a resurgence of interest in the moon as a target for planetary exploration. In light of the growing interest in the robotic exploration of the moon, this thesis presents a quantitative methodology for exploring the trade space of potential in situ robotic lunar spacecraft designs. A science value model was developed, using Multi-Attribute Utility Theory (MAUT), to estimate the effectiveness of a spacecraft design towards assessing a set of specified science objectives. An engineering model was developed to estimate the masses of spacecraft designs within the trade space. These models were integrated together to explore the objectives of minimizing mass and maximizing science return. Two methods for exploration of the trade space were presented: a stochastic design space search method, and a multi-objective simulated annealing method. Using these techniques, the optimality of a reference mission was investigated, and ways to improve science utility performance were shown. The exploration of a trade space under uncertainty, using an -Pareto search method, was investigated, and recommendations for designers were presented.by Zachary James Bailey.S.M

Rift Valley Fever Virus Infection in Golden Syrian Hamsters

Rift Valley fever virus (RVFV) is a formidable pathogen that causes severe disease and abortion in a variety of livestock species and a range of disease in humans that includes hemorrhagic fever, fulminant hepatitis, encephalitis and blindness. The natural transmission cycle involves mosquito vectors, but exposure can also occur through contact with infected fluids and tissues. The lack of approved antiviral therapies and vaccines for human use underlies the importance of small animal models for proof-of-concept efficacy studies. Several mouse and rat models of RVFV infection have been well characterized and provide useful systems for the study of certain aspects of pathogenesis, as well as antiviral drug and vaccine development. However, certain host-directed therapeutics may not act on mouse or rat pathways. Here, we describe the natural history of disease in golden Syrian hamsters challenged subcutaneously with the pathogenic ZH501 strain of RVFV. Peracute disease resulted in rapid lethality within 2 to 3 days of RVFV challenge. High titer viremia and substantial viral loads were observed in most tissues examined; however, histopathology and immunostaining for RVFV antigen were largely restricted to the liver. Acute hepatocellular necrosis associated with a strong presence of viral antigen in the hepatocytes indicates that fulminant hepatitis is the likely cause of mortality. Further studies to assess the susceptibility and disease progression following respiratory route exposure are warranted. The use of the hamsters to model RVFV infection is suitable for early stage antiviral drug and vaccine development studies

Male Circumcision in the General Population of Kisumu, Kenya: Beliefs about Protection, Risk Behaviors, HIV, and STIs

Using a population-based survey we examined the behaviors, beliefs, and HIV/HSV-2 serostatus of men and women in the traditionally non-circumcising community of Kisumu, Kenya prior to establishment of voluntary medical male circumcision services. A total of 749 men and 906 women participated. Circumcision status was not associated with HIV/HSV-2 infection nor increased high risk sexual behaviors. In males, preference for being or becoming circumcised was associated with inconsistent condom use and increased lifetime number of sexual partners. Preference for circumcision was increased with understanding that circumcised men are less likely to become infected with HIV

Co-transfer of functionally interdependent genes contributes to genome mosaicism in lambdoid phages

Lambdoid (or Lambda-like) phages, are a group of related temperate phages that can infect Escherichia coli and other gut bacteria. A key characteristic of these phages is their mosaic genome structure which served as basis for the "modular genome hypothesis". Accordingly, lambdoid phages evolve by transferring genomic regions, each of which constitutes a functional unit. Nevertheless, it is unknown which genes are preferentially transferred together and what drives such co-transfer events. Here we aim to characterize genome modularity by studying co-transfer of genes among 95 distantly related lambdoid (pro-)phages. Based on gene content, we observed that the genomes cluster into twelve groups, which are characterized by a highly similar gene content within the groups and highly divergent gene content across groups. Highly similar proteins can occur in genomes of different groups, indicating that they have been transferred. About 26% of homologous protein clusters in the four known operons (i.e., the early left, early right, immunity, and late operon) engage in gene transfer, which affects all operons to a similar extent. We identified pairs of genes that are frequently co-transferred and observed that these pairs tend to be in close proximity to one another on the genome. We find that frequently co-transferred genes are involved in related functions and highlight interesting examples involving structural proteins, the CI repressor and Cro regulator, proteins interacting with DNA, and membrane-interacting proteins. We conclude that epistatic effects, where the functioning of one protein depends on the presence of another, plays an important role in the evolution of the modular structure of these genomes

Evaluation of Participation and Environments for Individuals with Disabilities: An Evidence-Based Practice Project Bailey

This Evidence-Based Practice (EBP) project considered the following question: What measures are available to evaluate participation and environmental supports and barriers for individuals with disabilities and what are their psychometric properties