345 research outputs found

    Origins of inflated responsibility in obsessive compulsive disorder

    Full text link
    The pivotal role of inflated responsibility beliefs in the maintenance and treatment of obsessive-compulsive disorder (OCD) has been clearly demonstrated (Rachman, 1993; Salkovskis, 1998; Shafran, 1997; van Oppen & Arntz, 1994). Yet little is known about the origins of these beliefs, their contribution to a sense of inflated responsibility or the symptoms of OCD, or the contribution of personality to inflated responsibility and to OCD, The aims of this thesis were to investigate a model of the inter-relationships among the personality dimensions of neuroticism and psychoticism, inflated responsibility and OCD, and the origins of inflated responsibility to inflated responsibility and to OCD. In order to achieve these aims, a scale was developed to assess the origins of inflated responsibility based upon the five pathways proposed by Salkovskis, Shafran, Rachman, and Freeston (1999) and the additional domains of guilt, vigilance and thought-action fusion (Shafran, Thordarson, & Rachman, 1996; Shafran, Watkins & Charman, 1996; Tallis, 1994). Eighty-four participants with OCD (age M = 43.36) and 74 control participants (age M =37.14) volunteered to participate in the two studies of this thesis. The aim of Study 1 was to develop and validate a measure of the Origins of Inflated Responsibility (OIR). The results of the first study yielded a 25-ttem scale, the Origins of Inflated Responsibility Questionnaire (OIRQ) with five independent factors: responsibility, strictness, protection from responsibility, critical incidents, and peer blame which demonstrated both internal reliability and temporal stability over a 2-week period. In Study 2, participants also completed the Responsibility Attitudes Scale (Salkovskis, Wroe, Gledhill, Morrison, Forrester, Richards, ct al. (2000) (a measure of inflated responsibility), the Padua Inventory (Sanavio, 1988) (to measure of the symptoms of OCD)y and the Eysenck Personality Inventory-Revised (Eysenck & Eysenck, 1991). Multivariatc Analysis of Variance revealed that the OCD group scored higher on all variables than the control group except for strictness where the groups were not different, and psychoticism where the OCD group scored lower. A series of Multiple Regression analyses revealed that both group and the OIR contributed to inflated responsibility (R2 = .56). When all variables, OIR, inflated responsibility and neuroticism were entered as predictors of OCD, 60% of the variance in OCD was explained however, 49% of the variance was shared by the independent variables suggesting the presence of some underlying construct. Structural Equation Modelling, where all the constructs in the model were examined simultaneously, revealed that neuroticism contributed to the OIR, inflated responsibility and OCD. The OIR were also significant predictors of inflated responsibility and indirectly through inflated responsibility predictive of OCD. The OIR also directly predicted OCD and when the total effects are considered, their contribution was greater than the total effect for inflated responsibility alone. The results of these studies provide good support for the origins of inflated responsibility proposed by Salkovskis et al. (1999), as measured by the OIRQ developed for use in the current thesis. The results also support the contribution of inflated responsibility and neuroticism, as well as the OIR, to OCD, The large amount of variance shared by the OIR, inflated responsibility and neuroticism suggest that there might be some underlying construct, perhaps of a biopsychosocial nature, that requires further investigation for its role in the onset and maintenance of OCD. The clinical relevance of these findings is discussed in terms of early prevention strategies and interventions

    Biochemical Analysis of Human Cancer-Associated Pseudokinases

    Get PDF

    Validity and sensitivity of the phonics screening check : implications for practice

    Get PDF
    This is an Open Access article made available under the terms of the Creative Commons Attribution 3.0 Unported (CC BY 3.0) license https://creativecommons.org/licenses/by/3.0/ , which permits use, distribution and reproduction in any medium, provided the original work is properly cited.Background: Introduced in June 2012, the phonics screening check aims to assess whether 6-year-old children are meeting an appropriate standard in phonic decoding and to identify children struggling with phonic skills. Aims: We investigated whether the check is a valid measure of phonic skill and is sensitive in identifying children at risk of reading difficulties. Sample: We obtained teacher assessments of phonic skills for 292 six-year-old children and additional psychometric data for 160 of these children. Methods: Teacher assessment data were accessed from schools via the local authority; psychometric tests were administered by researchers shortly after the phonics screening check. Results: The check was strongly correlated with other literacy skills and was sensitive in identifying at-risk readers. So too were teacher judgements of phonics. Conclusions: Although the check fulfils its aims, we argue that resources might be better focused on training and supporting teachers in their ongoing monitoring of phonics.Peer reviewe

    Developing guidance for the appropriate use of Computed Tomography within a hybrid imaging environment

    Get PDF
    The introduction of Computed Tomography (CT) within the nuclear medicine environment over the last decade has led to a dramatic increase in the number of hybrid imaging installations within the United Kingdom. Modern multislice Single Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET)/CT units now have the diagnostic capability to provide a high level of anatomical information and have redefined the physical environment required for this imaging modality. This alongside current financial pressures impacting on the NHS has begun to challenge traditional working practices and an increased emphasis is now being placed on the healthcare practitioner to provide high quality care, demonstrate greater clinical effectiveness, improve safe working practices and to continuously adapt their skills to meet with the changing needs of the patient. Initial research conducted by the authors in collaboration with existing clinical nuclear medicine practitioners has indicated variation in the optimal use of CT within a hybrid-imaging environment. It is a concern that this apparent position within the hybrid imaging community does not appear to be conducive with current government initiatives related to optimal service provision. These inconsistencies would therefore appear to highlight the need for the development of a competency based framework that would provide the practitioner with the opportunity to develop their own working practices and help promote the harmonised use of CT within the hybrid imaging environment

    Small Scale Living

    Get PDF

    Design for sustainable behaviour: a quick fix for slower consumption?

    Get PDF
    The continuous replacement of durable consumer goods and disposal of functioning or repairable products into UK landfills or, increasingly, to developing countries, has resulted in global environmental and social consequences. Small appliances, which are easily disposed of in household waste, typically end up in UK landfills, are shipped to developing countries or otherwise ‘lost’. Very few are recycled or repaired, yet many are still functioning when disposed of. Consumers’ willingness, opportunity and ability to carry out repairs have historically been hampered by a range of complex factors. Design for Sustainable Behaviour (DfSB) aims to reduce the environmental and social impacts of products by moderating users’ interaction with them. This paper explores how DfSB strategies can be used to encourage a behavioural shift towards repair of small electrical household appliances by overcoming identified barriers. The paper pulls together literature on repair practice, highlighting gaps in current knowledge and outlines the findings of an extensive UK household survey focused on both product breakage rates and consumer mending behaviour. Three mending typologies and associated personas resulting from the analysis are combined with three DfSB strategies to develop conceptual design interventions to encourage repair. The paper concludes with a discussion of the potential efficacy of the design outcomes from a consumer perspective and the potential ramifications for design practice, whilst considering the wider influences on repair practices beyond design and how these may be addressed

    The rotation of alpha Oph investigated using polarimetry

    Get PDF
    Recently we have demonstrated that high-precision polarization observations can detect the polarization resulting from the rotational distortion of a rapidly rotating B-type star. Here we investigate the extension of this approach to an A-type star. Linear-polarization observations of α\alpha Oph (A5IV) have been obtained over wavelengths from 400 to 750 nm. They show the wavelength dependence expected for a rapidly-rotating star combined with a contribution from interstellar polarization. We model the observations by fitting rotating-star polarization models and adding additional constraints including a measured vesiniv_e \sin{i}. However, we cannot fully separate the effects of rotation rate and inclination, leaving a range of possible solutions. We determine a rotation rate ω=Ω/Ωc\omega = \Omega/\Omega_ c between 0.83 and 0.98 and an axial inclination i > 60 deg. The rotation-axis position angle is found to be 142 ±\pm 4 deg, differing by 16 deg from a value obtained by interferometry. This might be due to precession of the rotation axis due to interaction with the binary companion. Other parameters resulting from the analysis include a polar temperature Tp = 8725 ±\pm 175 K, polar gravity loggp=3.93±0.08\log{g_p} = 3.93 \pm 0.08 (dex cgs), and polar radius Rp=2.52±0.06R_{\rm p} = 2.52 \pm 0.06 Rsun. Comparison with rotating-star evolutionary models indicates that α\alpha Oph is in the later half of its main-sequence evolution and must have had an initial ω\omega of 0.8 or greater. The interstellar polarization has a maximum value at a wavelength (λmax\lambda_{\rm max}) of 440±110440 \pm 110 nm, consistent with values found for other nearby stars.Comment: 14 pages, 11 figures, 5 tables, Accepted in MNRA

    Potential for definitive discovery of a 70 GeV dark matter WIMP with only second-order gauge couplings

    Full text link
    As astronomical observations and their interpretation improve, the case for cold dark matter (CDM) becomes increasingly persuasive. A particularly appealing version of CDM is a weakly interacting massive particle (WIMP) with a mass near the electroweak scale, which can naturally have the observed relic abundance after annihilation in the early universe. But in order for a WIMP to be consistent with the currently stringent experimental constraints it must have relatively small cross-sections for indirect, direct, and collider detection. Using our calculations and estimates of these cross-sections, we discuss the potential for discovery of a recently proposed dark matter WIMP which has a mass of about 70 GeV/c2^2 and only second-order couplings to W and Z bosons. There is evidence that indirect detection may already have been achieved, since analyses of the gamma rays detected by Fermi-LAT and the antiprotons observed by AMS-02 are consistent with 70 GeV dark matter having our calculated σannv1.2×1026\langle \sigma_{ann} v \rangle \approx 1.2 \times 10^{-26} cm3^3/s. The estimated sensitivities for LZ and XENONnT indicate that these experiments may achieve direct detection within the next few years, since we estimate the relevant cross-section to be slightly above 104810^{-48} cm2^2. Other experiments such as PandaX, SuperCDMS, and especially DARWIN should be able to confirm on a longer time scale. The high-luminosity LHC might achieve collider detection within about 15 years, since we estimate a collider cross-section slightly below 1 femtobarn. Definitive confirmation should come from still more powerful planned collider experiments (such as a future circular collider) within 15-35 years.Comment: 6 page
    corecore