434 research outputs found

    Control, memoria y olvido: “Marcha de la Paz” y huelga ferroviaria durante el primer gobierno peronista

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    En nuestro artículo nos centraremos precisamente, en el análisis de dos situaciones conflictivas en las cuales el gobierno peronista y un sector particular del colectivo obrero - trabajadores ferroviarios - llegaron al enfrentamiento y donde el Estado adoptó medidas represivas para encauzar conductas que consideraba peligrosas. Nos interesó establecer como este proceder punitivo fue aplicado no sólo contra grupos inequívocamente opositores sino también sobre quienes defendían al gobierno peronista1. Consideramos que una doble estrategia de consenso y represión (efectiva o potencial) marcó la relación peronismo-trabajadores. El estímulo o censura de la movilización popular dependió de la seguridad de mantener el control por parte del Estado o de las organizaciones hegemonizadas por el peronismo.Fil: Badaloni, Laura Irene. Unidades En Red - Conicet. Investigaciones Socio-historicas Regionales. Centro de Estudios Sociales Regionales - Nodo Cesor - Ishir; Argentin

    Angela Vergara, Copper workers, international business, and domestic politics in cold war Chile, University Park, PA The Pennsylvania State University Press, 2008

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    Angela Vergara, Copper workers, international business, and domestic politics in cold war Chile, University Park, PA The Pennsylvania State University Press, 200

    A model study of corona emission from hydrometeors

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    The maximum measured electric fields in thunderclouds are an order of magnitude less than the fields required for electric breakdown of the air. One explanation for lightning initiation in these low fields is that electric breakdown first occurs at the surfaces of raindrops where the ambient field is enhanced very locally due to the drop geometry. Laboratory experiments [Crabb & Latham, 1974] indicate that colliding raindrops which coalesce to form elongated water filaments can produce positive corona in ambient fields close to those measured in thunderclouds. We calculate the E-field distribution around a simulated coalesced drop pair and use a numerical model to study the positive corona mechanisms in detail. Our results give good agreement with the laboratory observations. At the altitudes (and thus low pressures) at which lightning initiation is observed, our results show that positive corona can occur at observed in-cloud E-fields.Comment: 13 pages, 9 figures, http://www.geophys.washington.edu/Surface/Atmospheric/ Submitted to: Quarterly Journal of the Royal Meteorological Societ

    Primary Cardiac High-grade Myxofibrosarcoma Presenting with Multiple Brain Metastases: A Case Report

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    Herein we describe the case of a young patient who presented with a recent history of epilepsy due to multiple brain lesions; he did not complain about any cardiopulmonary impairments. The patient died as a consequence of hemorrhagic progression of brain metastatic disease. Regardless of a thorough investigation, the heart tumor remained occult. Primary cardiac tumors are very rare entities. Most of these are benign, but approximately 25% are malignant, and the majority of these are sarcomas. Myxofibrosarcoma and osteosarcoma are exceptionally rare. To date, we find only small series of cardiac myxofibrosarcoma, and to our knowledge, this one exceptionally presented with multiple brain metastatic lesions without cardiopulmonary symptoms

    MAB21L2, a vertebrate member of the Male-abnormal 21 family, modulates BMP signaling and interacts with SMAD1

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    BACKGROUND: Through in vivo loss-of-function studies, vertebrate members of the Male abnormal 21 (mab-21) gene family have been implicated in gastrulation, neural tube formation and eye morphogenesis. Despite mounting evidence of their considerable importance in development, the biochemical properties and nature of MAB-21 proteins have remained strikingly elusive. In addition, genetic studies conducted in C. elegans have established that in double mutants mab-21 is epistatic to genes encoding various members of a Transforming Growth Factor beta (TGF-beta) signaling pathway involved in the formation of male-specific sensory organs. RESULTS: Through a gain-of-function approach, we analyze the interaction of Mab21l2 with a TGF-beta signaling pathway in early vertebrate development. We show that the vertebrate mab-21 homolog Mab21l2 antagonizes the effects of Bone Morphogenetic Protein 4 (BMP4) overexpression in vivo, rescuing the dorsal axis and restoring wild-type distribution of Chordin and Xvent2 transcripts in Xenopus gastrulae. We show that MAB21L2 immunoprecipitates in vivo with the BMP4 effector SMAD1, whilst in vitro it binds SMAD1 and the SMAD1-SMAD4 complex. Finally, when targeted to an heterologous promoter, MAB21L2 acts as a transcriptional repressor. CONCLUSIONS: Our results provide the first biochemical and cellular foundation for future functional studies of mab-21 genes in normal neural development and its pathological disturbances

    Velocidad de convergencia de juego ficticio simultáneo y alternante

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    Extendemos algunos resultados sobre la convergencia de juego ficticio, permitiendo el uso de reglas de desempate, y probamos que existen juegos de 2 jugadores con dimensiones mínimas para los cuales la cantidad de pasos que se requiere antes de alcanzar un equilibrio de Nash puro es exponencial en el tamaño de representación de las matrices de utilidad, tanto para el juego ficticio simultáneo como para el alternante.Sociedad Argentina de Informática e Investigación Operativ

    ZFP423 Coordinates Notch and Bone Morphogenetic Protein Signaling, Selectively Up-regulating Hes5 Gene Expression

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    Zinc finger protein 423 encodes a 30 Zn-finger transcription factor involved in cerebellar and olfactory development. ZFP423 is a known interactor of SMAD1-SMAD4 and of Collier/Olf-1/EBF proteins, and acts as a modifier of retinoic acid-induced differentiation. In the present article, we show that ZFP423 interacts with the Notch1 intracellular domain in mammalian cell lines and in Xenopus neurula embryos, to activate the expression of the Notch1 target Hes5/ESR1. This effect is antagonized by EBF transcription factors, both in cultured cells and in Xenopus embryos, and amplified in vitro by BMP4, suggesting that ZFP423 acts to integrate BMP and Notch signaling, selectively promoting their convergence onto the Hes5 gene promoter
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