1,019 research outputs found
Electromagnetics from a quasistatic perspective
Quasistatics is introduced so that it fits smoothly into the standard
textbook presentation of electrodynamics. The usual path from statics to
general electrodynamics is rather short and surprisingly simple. A closer look
reveals however that it is not without confusing issues as has been illustrated
by many contributions to this Journal. Quasistatic theory is conceptually
useful by providing an intermediate level in between statics and the full set
of Maxwell's equations. Quasistatics is easier than general electrodynamics and
in some ways more similar to statics. It is however, in terms of interesting
physics and important applications, far richer than statics. Quasistatics is
much used in electromagnetic modeling, an activity that today is possible on a
PC and which also has great pedagogical potential. The use of electromagnetic
simulations in teaching gives additional support for the importance of
quasistatics. This activity may also motivate some change of focus in the
presentation of basic electrodynamics
Comparative Raman Studies of Sr2RuO4, Sr3Ru2O7 and Sr4Ru3O10
The polarized Raman spectra of layered ruthenates of the Srn+1RunO3n+1
(n=1,2,3) Ruddlesden-Popper series were measured between 10 and 300 K. The
phonon spectra of Sr3Ru2O7 and Sr4Ru3O10 confirmed earlier reports for
correlated rotations of neighboring RuO6 octahedra within double or triple
perovskite blocks. The observed Raman lines of Ag or B1g symmetry were assigned
to particular atomic vibrations by considering the Raman modes in simplified
structures with only one double or triple RuO6 layer per unit cell and by
comparison to the predictions of lattice dynamical calculations for the real
Pban and Pbam structures. Along with discrete phonon lines, a continuum
scattering, presumably of electronic origin, is present in the zz, xx and xy,
but not in the x'y' and zx spectra. Its interference with phonons results in
Fano shape for some of the lines in the xx and xy spectra. The temperature
dependencies of phonon parameters of Sr3Ru2O7 exhibit no anomaly between 10 and
300 K where no magnetic transition occurs. In contrast, two B1g lines in the
spectra of Sr4Ru3O10, corresponding to oxygen vibrations modulating the Ru-O-Ru
bond angle, show noticeable hardening with ferromagnetic ordering at 105 K,
thus indicating strong spin-phonon interaction.Comment: 9 pages, 12 figure
Flow graphs: interweaving dynamics and structure
The behavior of complex systems is determined not only by the topological
organization of their interconnections but also by the dynamical processes
taking place among their constituents. A faithful modeling of the dynamics is
essential because different dynamical processes may be affected very
differently by network topology. A full characterization of such systems thus
requires a formalization that encompasses both aspects simultaneously, rather
than relying only on the topological adjacency matrix. To achieve this, we
introduce the concept of flow graphs, namely weighted networks where dynamical
flows are embedded into the link weights. Flow graphs provide an integrated
representation of the structure and dynamics of the system, which can then be
analyzed with standard tools from network theory. Conversely, a structural
network feature of our choice can also be used as the basis for the
construction of a flow graph that will then encompass a dynamics biased by such
a feature. We illustrate the ideas by focusing on the mathematical properties
of generic linear processes on complex networks that can be represented as
biased random walks and also explore their dual consensus dynamics.Comment: 4 pages, 1 figur
Analytical reasoning task reveals limits of social learning in networks
Social learning -by observing and copying others- is a highly successful
cultural mechanism for adaptation, outperforming individual information
acquisition and experience. Here, we investigate social learning in the context
of the uniquely human capacity for reflective, analytical reasoning. A hallmark
of the human mind is our ability to engage analytical reasoning, and suppress
false associative intuitions. Through a set of lab-based network experiments,
we find that social learning fails to propagate this cognitive strategy. When
people make false intuitive conclusions, and are exposed to the analytic output
of their peers, they recognize and adopt this correct output. But they fail to
engage analytical reasoning in similar subsequent tasks. Thus, humans exhibit
an 'unreflective copying bias,' which limits their social learning to the
output, rather than the process, of their peers' reasoning -even when doing so
requires minimal effort and no technical skill. In contrast to much recent work
on observation-based social learning, which emphasizes the propagation of
successful behavior through copying, our findings identify a limit on the power
of social networks in situations that require analytical reasoning
An efficient and principled method for detecting communities in networks
A fundamental problem in the analysis of network data is the detection of
network communities, groups of densely interconnected nodes, which may be
overlapping or disjoint. Here we describe a method for finding overlapping
communities based on a principled statistical approach using generative network
models. We show how the method can be implemented using a fast, closed-form
expectation-maximization algorithm that allows us to analyze networks of
millions of nodes in reasonable running times. We test the method both on
real-world networks and on synthetic benchmarks and find that it gives results
competitive with previous methods. We also show that the same approach can be
used to extract nonoverlapping community divisions via a relaxation method, and
demonstrate that the algorithm is competitively fast and accurate for the
nonoverlapping problem.Comment: 14 pages, 5 figures, 1 tabl
Incidence, management, and outcomes of cardiovascular insufficiency in critically ill term and late preterm newborn infants
OBJECTIVE:
The objective of this study was to characterize the incidence, management, and short-term outcomes of cardiovascular insufficiency (CVI) in mechanically ventilated newborns, evaluating four separate prespecified definitions.
STUDY DESIGN:
Multicenter, prospective cohort study of infants ≥34 weeks gestational age (GA) and on mechanical ventilation during the first 72 hours. CVI was prospectively defined as either (1) mean arterial pressure (MAP) < GA; (2) MAP < GA + signs of inadequate perfusion; (3) any therapy for CVI; or (4) inotropic therapy. Short-term outcomes included death, days on ventilation, oxygen, and to full feedings and discharge.
RESULTS:
Of 647 who met inclusion criteria, 419 (65%) met ≥1 definition of CVI. Of these, 98% received fluid boluses, 36% inotropes, and 17% corticosteroids. Of treated infants, 46% did not have CVI as defined by a MAP < GA ± signs of inadequate perfusion. Inotropic therapy was associated with increased mortality (11.1 vs. 1.3%; p < 0.05).
CONCLUSION:
More than half of the infants met at least one definition of CVI. However, almost half of the treated infants met none of the definitions. Inotropic therapy was associated with increased mortality. These findings can help guide the design of future studies of CVI in newborn
Understanding the interplay between social and spatial behaviour
According to personality psychology, personality traits determine many aspects of human behaviour. However, validating this insight in large groups has been challenging so far, due to the scarcity of multi-channel data. Here, we focus on the relationship between mobility and social behaviour by analysing trajectories and mobile phone interactions of ∼1000 individuals from two high-resolution longitudinal datasets. We identify a connection between the way in which individuals explore new resources and exploit known assets in the social and spatial spheres. We show that different individuals balance the exploration-exploitation trade-off in different ways and we explain part of the variability in the data by the big five personality traits. We point out that, in both realms, extraversion correlates with the attitude towards exploration and routine diversity, while neuroticism and openness account for the tendency to evolve routine over long time-scales. We find no evidence for the existence of classes of individuals across the spatio-social domains. Our results bridge the fields of human geography, sociology and personality psychology and can help improve current models of mobility and tie formation
Estimating sampling biases in citizen science datasets
The rise of citizen science (also called community science) has led to vast quantities of species observation data collected by members of the public. Citizen science data tend to be unevenly distributed across space and time, but the treatment of sampling bias varies between studies, and interactions between different biases are often overlooked. We present a method for conceptualizing and estimating spatial and temporal sampling biases, and interactions between them. We use this method to estimate sampling biases in an example ornithological citizen science dataset from eBird in Brisbane City, Australia. We then explore the effects of these sampling biases on subsequent model inference of population trends, using both a simulation study and an application of the same trend models to the Brisbane eBird dataset. We find varying levels of sampling bias in the Brisbane eBird dataset across temporal and spatial scales, and evidence for interactions between biases. Several of the sampling biases we identified differ from those described in the literature for other datasets, with protected areas being undersampled in the city, and only limited seasonal sampling bias. We demonstrate variable performance of trend models under different sampling bias scenarios, with more complex biases being associated with typically poorer trend estimates. Sampling biases are important to consider when analysing ecological datasets, and analysts can use this method to ensure that any biologically relevant sampling biases are detected and given due consideration during analysis. With appropriate model specification, the effects of sampling biases can be reduced to yield reliable information about biodiversity.Peer reviewe
Safety and pharmacokinetics of multiple dose myo-inositol in preterm infants
BACKGROUND:
Preterm infants with respiratory distress syndrome (RDS) given inositol had reduced bronchopulmonary dysplasia (BPD), death and severe retinopathy of prematurity (ROP). We assessed the safety and pharmacokinetics of daily inositol to select a dose providing serum levels previously associated with benefit, and to learn if accumulation occurred when administered throughout the normal period of retinal vascularization.
METHODS:
Infants ≤ 29 wk GA (n = 122, 14 centers) were randomized and treated with placebo or inositol at 10, 40, or 80 mg/kg/d. Intravenous administration converted to enteral when feedings were established, and continued to the first of 10 wk, 34 wk postmenstrual age (PMA) or discharge. Serum collection employed a sparse sampling population pharmacokinetics design. Inositol urine losses and feeding intakes were measured. Safety was prospectively monitored.
RESULTS:
At 80 mg/kg/d mean serum levels reached 140 mg/l, similar to Hallman's findings. Levels declined after 2 wk, converging in all groups by 6 wk. Analyses showed a mean volume of distribution 0.657 l/kg, clearance 0.058 l/kg/h, and half-life 7.90 h. Adverse events and comorbidities were fewer in the inositol groups, but not significantly so.
CONCLUSION:
Multiple dose inositol at 80 mg/kg/d was not associated with increased adverse events, achieves previously effective serum levels, and is appropriate for investigation in a phase III trial
Novel Approach to Mass Tort Class Actions: The Billion Dollar Settlement in the Sulzer Artificial Hip and Knee Litigation: A Symposium
This is a transcript of a two hour symposium which deals with the Sulzer knee and hip replacement class action. A copy of the settlement is included as an appendix. The settlement in the U.S. District Court for the N.D. Ohio was unique and creative approach to resolving a mass tort class action. In a novel move, Sulzer agreed to open its books to an independent review firm to determine how much the firm could pay without going bankrupt. The number was $1 billion. As negotiated by the parties and approved by the court, the final settlement provides compensation for each member of the class based on a variety of factors, such as whether the member has undergone - or is likely to undergo - a revision to replace the defective part. Professor Susan Becker made the introductory remarks. The panel members were all involved in the Sulzer knee and hip replacement class action. R. Eric Kennedy served as lead plaintiffs\u27 counsel. The Honorable Kathleen McDonald O\u27Malley of the U.S. District Court for the Northern District of Ohio presided over the Sulzer class action litigation and settlement. Sidney A. Backstrom and Richard F. Scruggs were the defense counsel. James J. McMonagle served as the Claims Administrator overseeing distribution of the Sulzer class action settlement funds
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