Knowledge, stress and adopted coping strategies of parents of children having congenital adrenal hyperplasia: An exploratory survey

Background: Congenital adrenal hyperplasia (CAH) is an inherited disorder of adrenal glands, the most common type being due to a deficiency of the enzyme 21-α-hydroxylase. Girls affected with it are virilized to a variable extent. The taboo associated with ambiguous genitalia in female babies poses an immense societal pressure on parents for keeping the disease a secret. Objective: The aim of the study was to generate the evidence on the knowledge, stress, and coping strategies used by the parents of CAH children. Methodology: In a cross-sectional descriptive survey using mixed methods approach, 30 parents of children with CAH attending the outdoor department of pediatric medicine and surgery in a tertiary care hospital were enrolled. The CAH knowledge questionnaire, parental stress scale (PSS), and COPE inventory were the standardized tools used along with demographic profile sheet to assess the knowledge of parents related to CAH, stress, and coping strategies used by them. Results: Majority of the parents (67%) had poor knowledge (<7) and moderate stress (42-65) scores. Knowledge and stress were negatively correlated (r=−0.39, p=0.035). Coping strategies used by the parents in dealing with stress in moderate amount were mainly problem-focused (active coping [60%] and planning [60%], instrumental social support [53%], suppression of competing activities [50%]), and emotion-focused (positive reinterpretation [60%], emotional social support [67%], acceptance [53%], and religious coping [50%]). Less useful coping strategies such as focus on and venting of emotions, behavioral disengagement, mental disengagement, humor, and substance abuse were not used by the majority parents. Conclusion: Parents of children with CAH had poor knowledge and moderate stress related to the disease condition of their children and were using problem focused and emotion focused coping strategies to reduce their stress

Bacterial community structure analysis of soil treated with Parthenium hysterophorus L. derived green medium

The present study encompasses the analysis of bacterial community structure of soil in the presence of Parthenium hysterophorus derived green medium. The 16S microbiome profiling of the soil revealed that it consists of members from 15 bacterial phyla with the most prominent being Proteobacteria. The other predominant phyla were Plantomycetes, Actinobacteria, Acidobacteria, Bacteroidetes, Chloroflexi and Firmicutes. The maximum proportion of the bacterial community remained unclassified at genus and species level. Among the classified population the maximum number of bacteria belonged to Flavisolibacter followed by Kaistobacter, Bacillus, Optitutus, Balneimonas, Steroidobacter, Rhodoplanes and Gemmata

An application of ordinal regression to extract social dysfunction levels through behavioral problems

Psychological problems are complex in nature and accurate identification of these problems is important. For the identification of psychological problems, one of the preliminary tools is the use of interviews/questionnaires. Questionnaires are preferred over interviews if the group under study is large. A strengths and difficulties questionnaire (SDQ) is one of the most widely used and powerful questionnaires to identify behavioral problems and distresses being faced by the respondents, affecting their day-to-day lives (responsible for social dysfunction). This study was held on college/university students in India, with the objective of examining if the extent of social dysfunction as measured by an impact score can be extracted from behavioral problems which are the components of the difficulty score of SDQ. Two surveys were conducted during the COVID-19 pandemic period, between the months of May–June 2020 and October 2020–February 2021 for the study. Only those responses were considered who felt distressed (“yes” to item 26 of SDQ). The numbers of such responses were 772/1020 and 584/743, respectively, in the two surveys. Distress levels were treated as ordered variables and three categories of distress level, viz., “Normal”, “Borderline”, and “Abnormal” were estimated through behavioral problems using ordinal regression (OR) methods with a negative log-log link function. The fitting of OR models was tested and accepted using Cox and Snell, Nagelkerke, and McFadden test. Hyperactivity-inattention and emotional symptoms were significant contributors to estimating levels of distress among respondents in survey 1 (p < 0.05). In addition to these components, in survey 2, peer problems were also significant. OR models were good at estimating the extreme categories; however, the “Borderline” category was not estimated well. One of the reasons was the use of qualitative and complex data with the least wide “Borderline” category, both for the “Difficulty” and the “Impact” scores

Challenges in Creation and Management of Knowledge Capital in Technical Educational Institutions

340-345 The global knowledge economy has put the focus on local centres of economic growth and depends on the capacity of institutions and organizations to continually reinvent and reconfigure themselves and their environment. In this context, certain parameters were taken into consideration for a better understanding of how institutions deploy their core resources and competencies towards IP creation and management. This paper examines some of the challenges faced in IP creation for India and suggests approach to effectively manage the knowledge capital. In particular, the objectives of the study are assessment and identification of issues in creation of IP in technical institutions, and finding appropriate measures to address these issues. </smarttagtype

Chloroplast Genome of Lithocarpus&nbsp;dealbatus (Hook.f. &amp; Thomson ex Miq.) Rehder Establishes Monophyletic Origin of the Species and Reveals Mutational Hotspots with Taxon Delimitation Potential

There is phylogenetic ambiguity in the genus Lithocarpus and subfamily Quercoideae (Family: Fagaceae). Lithocarpus dealbatus, an ecologically important tree, is the dominant species among the Quercoideae in India. Although several studies have been conducted on the species&rsquo; regeneration and ecological and economic significance, limited information is available on its phylo-genomics. To resolve the phylogeny in Quercoideae, we sequenced and assembled the 161,476 bp chloroplast genome of L. dealbatus, which has a large single-copy section of 90,732 bp and a small single-copy region of 18,987 bp, separated by a pair of inverted repeat regions of 25,879 bp. The chloroplast genome contained 133 genes, of which 86 were protein-coding genes, 39 were transfer RNAs, and eight were ribosomal RNAs. Analysis of repeat elements and RNA editing sites revealed interspecific similarities within the Lithocarpus genus. DNA diversity analysis identified five highly diverged coding and noncoding hotspot regions in the four genera, which can be used as polymorphic markers for species/taxon delimitation across the four genera of Quercoideae viz., Lithocarpus, Quercus, Castanea, and Castanopsis. The chloroplast-based phylogenetic analysis among the Quercoideae established a monophyletic origin of Lithocarpus, and a closer evolutionary lineage with a few Quercus species. Besides providing insights into the chloroplast genome architecture of L. dealbatus, the study identified five mutational hotspots having high taxon-delimitation potential across four genera of Quercoideae