295 research outputs found

    FISHRENT; Bio-economic simulation and optimisation model

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    Key findings: The FISHRENT model is a major step forward in bio-economic model-ling, combining features that have not been fully integrated in earlier models: 1- Incorporation of any number of species (or stock) and/or fleets 2- Integration of simulation and optimisation over a period of 25 years 3- Integration of effort and TAC-driven management policies 4- Three independent relations for stock growth, production and investments. The feedbacks within the model allow for a dynamic simulation. The main application of the model is scenario analysis of policy options. Complementary findings: The model formulates a complete set of mathematical relations, but it also con-tains a number of important assumptions, which remain to be tested empirically. Therefore the model presents a challenging agenda for empirical research, which should lead to further qualitative and quantitative improvements of the in-dividual mathematical equations and parameter values. Method: This model was developed during the EU-funded project 'Remuneration of spawning stock biomass'. Its aim was to generate consistent sets of scenarios for an assessment of potential resource rents in different EU fisheries. The model comprises six modules, each focussing on a different aspect of the functioning of the fisheries system: biology (stocks), economy (costs, earnings and profits), policy (TACs, effort and access fees), behaviour (investments), prices (fish and fuel) and an interface linking the modules together. Input, calculation and output are clearly separated. The model produces a standard set of graphics, which provide a quick insight into the results of any model run. All output of the model runs can be exported to database software for further analysis. The model has been built in Excel, which makes it accessible for most us-ers. It has been used in new applications and even translated to other software. The model is continually further developed

    Foster parent stress as key factor relating to foster children’s mental health: a 1-year prospective longitudinal study

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    Development Psychopathology in context: schoolEducation and Child StudiesDevelopment Psychopathology in context: clinical settingsDevelopment Psychopathology in context: famil

    Megacrystals track magma convection between reservoir and surface

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    Active volcanoes are typically fed by magmatic reservoirs situated within the upper crust. The development of thermal and/or compositional gradients in such magma chambers may lead to vigorous convection as inferred from theoretical models and evidence for magma mixing recorded in volcanic rocks. Bi-directional flow is also inferred to prevail in the conduits of numerous persistently-active volcanoes based on observed gas and thermal emissions at the surface, as well as experiments with analogue models. However, more direct evidence for such exchange flows has hitherto been lacking. Here, we analyse the remarkable oscillatory zoning of anorthoclase feldspar megacrystals erupted from the lava lake of Erebus volcano, Antarctica. A comprehensive approach, combining phase equilibria, solubility experiments and melt inclusion and textural analyses shows that the chemical profiles are best explained as a result of multiple episodes of magma transport between a deeper reservoir and the lava lake at the surface. Individual crystals have repeatedly travelled up-and-down the plumbing system, over distances of up to several kilometers, presumably as a consequence of entrainment in the bulk magma flow. Our findings thus corroborate the model of bi-directional flow in magmatic conduits. They also imply contrasting flow regimes in reservoir and conduit, with vigorous convection in the former (regular convective cycles of ∼150 days at a speed of ∼0.5 mm s−1) and more complex cycles of exchange flow and re-entrainment in the latter. We estimate that typical, 1-cm-wide crystals should be at least 14 years old, and can record several (from 1 to 3) complete cycles between the reservoir and the lava lake via the conduit. This persistent recycling of phonolitic magma is likely sustained by CO2 fluxing, suggesting that accumulation of mafic magma in the lower crust is volumetrically more significant than that of evolved magma within the edifice.The work reported here has been partially supported by the National Science Foundation (Division of Polar Programs) under grant ANT1142083. The authors thank the Natural Environment Research Council (NERC) for access to the NERC Ion Microprobe Facility (Grant IMF453/1011) and Richard Hinton for invaluable help with SIMS analyses. Y.M. acknowledges support from the Cambridge Philosophical Society, the University of Cambridge Home and EU Scholarship Scheme, and the Philip Lake and William Vaughan Lewis funds from the Department of Geography, University of Cambridge. Y.M. also acknowledges support from ERC grant #279790.This is the final published version. It first appeared at http://www.sciencedirect.com/science/article/pii/S0012821X14007833#

    Modelling intentions to provide smoking cessation support among mental health professionals in the Netherlands

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    Development Psychopathology in context: famil

    Monophyletic group of unclassified γ-Proteobacteria dominates in mixed culture biofilm of high-performing oxygen reducing biocathode

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    International audienceSeveral mixed microbial communities have been reported to show robust bioelectrocatalysis of oxygen reduction over time at applicable operation conditions. However, clarification of electron transfer mechanism(s) and identification of essential micro-organisms have not been realised. Therefore, the objective of this study was to shape oxygen reducing biocathodes with different microbial communities by means of surface modification using the electrochemical reduction of two different diazonium salts in order to discuss the relation of microbial composition and performance. The resulting oxygen reducing mixed culture biocathodes had complex bacterial biofilms variable in size and shape as observed by confocal and electron microscopy. Sequence analysis of ribosomal 16S rDNA revealed a putative correlation between the abundance of certain microbiota and biocathode performance. The best performing biocathode developed on the unmodified graphite electrode and reached a high current density for oxygen reducing biocathodes at neutral pH (0.9A/m(2)). This correlated with the highest domination (60.7%) of a monophyletic group of unclassified γ-Proteobacteria. These results corroborate earlier reports by other groups, however, higher current densities and higher presence of these unclassified bacteria were observed in this work. Therefore, members of this group are likely key-players for highly performing oxygen reducing biocathodes.[on SciFinder (R)

    Serum IgA Responses against Pertussis Proteins in Infected and Dutch wP or aP Vaccinated Children: An Additional Role in Pertussis Diagnostics

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    BACKGROUND: Whooping cough is a respiratory disease caused by Bordetella pertussis, which induces mucosal IgA antibodies that appear to be relevant in protection. Serum IgA responses are measured after pertussis infection and might provide an additional role in pertussis diagnostics. However, the possible interfering role for pertussis vaccinations in the induction of serum IgA antibodies is largely unknown. METHODS/PRINCIPAL FINDINGS: We compared serum IgA responses in healthy vaccinated children between 1 and 10 years of age with those in children who despite vaccinations recently were infected with Bordetella pertussis. All children have been vaccinated at 2, 3, 4 and 11 months of age with either the Dutch whole-cell pertussis (wP) vaccine or an acellular pertussis (aP) vaccine and additionally received an aP booster vaccination at 4 years of age. Serum IgA responses to pertussis toxin (PT), filamentous heamagglutinin (FHA) and pertactin (Prn) were measured with a fluorescent multiplex bead-based immuno-assay. An ELISPOT-assay was used for the detection of IgA-memory B-cells specific to these antigens. Serum IgA levels to all pertussis vaccine antigens were significantly higher in infected children compared with healthy children. High correlations between anti-PT, anti-FHA or anti-Prn IgA and IgG levels were found in infected children and to some degree in wP primed children, but not at all in aP primed children. Highest numbers of IgA-pertussis-specific memory B-cells were observed after infection and generally comparable numbers were found after wP and aP vaccination. CONCLUSIONS: This study provides new insight in the diagnostic role for serum IgA responses against PT in vaccinated children. Since aP vaccines induce high serum IgG levels that interfere with pertussis diagnostics, serum IgA-PT levels will provide an additional diagnostic role. High levels of serum IgA for PT proved specific for recent pertussis infection with reasonable sensitivity, whereas the role for IgA levels against FHA and Prn in diagnosing pertussis remains controversial

    Marine Sediment Mixed With Activated Carbon Allows Electricity Production and Storage From Internal and External Energy Sources: A New Rechargeable Bio-Battery With Bi-Directional Electron Transfer Properties

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    Marine sediment has a great potential to generate electricity with a bioelectrochemical system (BES) like the microbial fuel cell (MFC). In this study, we investigated the potential of marine sediment and activated carbon (AC) to generate and store electricity. Both internal and external energy supply was validated for storage behavior. Four types of anode electrode compositions were investigated. Two types were mixtures of different volumes of AC and Dutch Eastern Scheldt marine sediment (67% AC and 33% AC) and the others two were 100% AC or 100% marine sediment based. Each composition was duplicated. Operating these BES’s under MFC mode with solely marine sediment as the anode electron donor resulted in the creation of a bio-battery. The recharge time of such bio-battery does depend on the fuel content and its usage. The results show that by usage of marine sediment and AC electricity was generated and stored. The 100% AC and the 67% AC mixed with marine sediment electrode were over long term potentiostatic controlled at -100 mV vs. Ag/AgCl which resulted in a cathodic current and an applied voltage. After switching back to the MFC operation mode at 1000 Ω external load, the electrode turned into an anode and electricity was generated. This supports the hypothesis that external supply electrical energy was recovered via bi-directional electron transfer. With open cell voltage experiments these AC marine bioanodes showed internal supplied electric charge storage up to 100 mC at short self-charging times (10 and 60 s) and up to 2.4°C (3,666 C/m3 anode) at long charging time (1 h). Using a hypothetical cell voltage of 0.2 V, this value represents an internal electrical storage density of 0.3 mWh/kg AC marine anode. Furthermore it was remarkable that the BES with 100% marine sediment based electrode also acted like a capacitor similar to the charge storage behaviors of the AC based bioanodes with a maximum volumetric storage of 1,373 C/m3 anode. These insights give opportunities to apply such BES systems as e.g., ex situ bio-battery to store and use electricity for off-grid purpose in remote areas

    The reliability and reproducibility of the Hertel classification for comminuted proximal humeral fractures compared with the Neer classification

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    _Introduction_ The Neer classification is the most commonly used fracture classification system for proximal humeral fractures. Inter- and intra-observer agreement is limited, especially for comminuted fractures. A possibly more straightforward and reliable classification system is the Hertel classification. The aim of this study was to compare the inter- and intra-observer variability of the Hertel with the Neer classification in comminuted proximal humeral fractures. _Materials and methods_ Four observers evaluated blinded radiographic images of 60 patients. After at least two months classification was repeated. _Results_ Inter-observer agreement on plain X-rays was fair for both Hertel and Neer. Inter-observer agreement on CT-scans was substantial for Hertel and moderate for Neer. Inter-observer agreement on 3D-reconstructions was moderate for both Hertel and Neer. Intra-observer agreement on plain X-rays was fair for both Hertel and Neer. Intra-observer agreement on CT-scans was moderate for both Hertel and Neer. Intra-observer agreement on 3D-reconstructions was moderate for Hertel and substantial for Neer. _Conclusions_ The Hertel and Neer classifications showed a fair to substantial inter- and intra-observer agreement on the three diagnostic modalities used. Although inter-observer agreement was highest for Hertel classification on CT-scans, Neer classification had the highest intra-observer agreement on 3D-reconstructions. Data of this study do not confirm superiority of either classification system for the classification of comminuted proximal humeral fractures
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