12 research outputs found

    Matching model of flow table for networked big data

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    Networking for big data has to be intelligent because it will adjust data transmission requirements adaptively during data splitting and merging. Software-defined networking (SDN) provides a workable and practical paradigm for designing more efficient and flexible networks. Matching strategy in the flow table of SDN switches is most crucial. In this paper, we use a classification approach to analyze the structure of packets based on the tuple-space lookup mechanism, and propose a matching model of the flow table in SDN switches by classifying packets based on a set of fields, which is called an F-OpenFlow. The experiment results show that the proposed F-OpenFlow effectively improves the utilization rate and matching efficiency of the flow table in SDN switches for networked big data.Comment: 14 pages, 6 figures, 2 table

    Choice of Oral Anticoagulant: Outcomes in Atrial Fibrillation Patients Post-Stroke Despite Direct Oral Anticoagulant Use

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    Background: For patients with atrial fibrillation who have an ischemic stroke or transient ischemic attack (TIA) despite taking direct oral anticoagulants (DOACs), the optimal strategy for ongoing anticoagulation is unknown. Methods: Using provincial administrative databases in Alberta, Canada, we compared anticoagulant use before/after the breakthrough stroke/TIA and assessed recurrence of stroke/TIA or bleeding, with consideration of medication adherence. Adherence was defined as the proportion of days covered (PDC) being ≄ 80%. Results: Among 985 patients, the median age was 80 years (interquartile range 13), with a mean CHADS2 score of 1.7± 1 prior to the index event. Patients were followed for a median of 643 days (interquartile range 836). Following the index stroke/TIA event, 623 patients (63%) filled a prescription for the same DOAC regimen, 83 (8%) filled a prescription for a different dose, 155 (16%) switched DOAC agents, 51 (5%) switched to warfarin, and 73 (7%) filled no oral anticoagulant prescription. Patients who kept the same regimen more commonly had TIA index events (59%); patients who changed dose or drug more often had stroke index events (55%-78%). During follow-up, 135 (14%) had stroke/TIA recurrence, and 46 (5%) had bleeding; rates of each did not differ between prescribing patterns. Post-index event, the proportion of patients with a proportion of days covered ≄ 80% improved from 55% to 80%. Conclusions: Although most maintained the same DOAC regimen after stroke/TIA, rates of recurrent stroke/TIA and bleeding were similar across prescribing patterns. Stroke/TIA severity may have influenced prescribing practices. DOAC prescription adherence improved poststroke/TIA and signals an opportunity for optimization in patients with atrial fibrillation. RĂ©sumĂ©: Contexte: Chez les patients atteints de fibrillation auriculaire qui subissent un accident vasculaire cĂ©rĂ©bral (AVC) ischĂ©mique ou un accident ischĂ©mique transitoire (AIT) malgrĂ© la prise d’anticoagulants oraux directe (AOD), la stratĂ©gie optimale pour la poursuite de l’anticoagulation est inconnue. MĂ©thodologie: À partir des bases de donnĂ©es administratives provinciales en Alberta, au Canada, nous avons comparĂ© l’utilisation d’anticoagulants avant/aprĂšs l’AVC/AIT survenu pendant l’anticoagulothĂ©rapie et avons Ă©valuĂ© la rĂ©currence d’un AVC/AIT ou d’un saignement, en tenant compte de l’adhĂ©sion au traitement mĂ©dicamenteux. L’adhĂ©sion a Ă©tĂ© dĂ©finie comme une proportion de jours couverts (PJC) de 80 % ou plus. RĂ©sultats: Chez 985 patients, l’ñge mĂ©dian Ă©tait de 80 ans (Ă©cart interquartile de 13) et le score CHADS2 moyen, de 1,7 ± 1 avant l’évĂ©nement de rĂ©fĂ©rence. Les patients ont Ă©tĂ© suivis pendant une mĂ©diane de 643 jours (Ă©cart interquartile de 836). AprĂšs l’AVC/AIT de rĂ©fĂ©rence, 623 patients (63 %) ont fait exĂ©cuter une ordonnance du mĂȘme schĂ©ma d’AOD, 83 (8 %) ont fait exĂ©cuter une ordonnance d’une dose diffĂ©rente, 155 (16 %) sont passĂ©s Ă  d’autres AOD, 51 (5 %) sont passĂ©s Ă  la warfarine et 73 (7 %) n’ont fait exĂ©cuter aucune ordonnance d’anticoagulant oral. Chez les patients qui ont continuĂ© Ă  recevoir le mĂȘme schĂ©ma, la plupart (59 %) avaient eu un AIT comme Ă©vĂ©nement de rĂ©fĂ©rence; chez les patients qui ont changĂ© de dose ou de mĂ©dicament, la plupart (55 Ă  78 %) avaient eu un AVC comme Ă©vĂ©nement de rĂ©fĂ©rence. Durant le suivi, 135 (14 %) ont connu un AVC/AIT rĂ©current et 46 (5 %) ont prĂ©sentĂ© un saignement; les taux de chaque manifestation ont Ă©tĂ© similaires pour les diffĂ©rents schĂ©mas de prescription. AprĂšs l’évĂ©nement de rĂ©fĂ©rence, le pourcentage de patients ayant une PJC ≄ 80 % a augmentĂ©, passant de 55 Ă  80 %. Conclusions: MalgrĂ© le maintien du mĂȘme schĂ©ma d’AOD chez la plupart des patients aprĂšs l’AVC/AIT, les taux d’AVC/AIT rĂ©current et de saignement ont Ă©tĂ© similaires avec tous les schĂ©mas de prescription. La gravitĂ© d’un AVC/AIT pourrait avoir influencĂ© les pratiques de prescription. L’adhĂ©sion aux AOD prescrits s’est amĂ©liorĂ©e aprĂšs un AVC/AIT et tĂ©moigne d’une possibilitĂ© d’optimisation chez les patients atteints de fibrillation auriculaire

    The Philippines

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    The Philippines is a large archipelago of over 7000 islands, mostly lined by coral reefs, seagrass meadows, and mangrove forests, and surrounded by waters with variable currents driven by a reversing monsoon system. The islands have narrow coastal plains, north-south mountain ranges, active volcanoes, and high seismological activity. These elements, along with the country’s complex geologic history and geographic position, make the Philippines one of the most biologically diverse, most disaster prone, and most environmentally threatened in the world. High dependence on coastal resources, overfishing and destructive fishing, and high rates of habitat loss make fishers in the country the poorest of the poor. The large population sizes and disproportionate impact of climate change here makes the poor’s situation worse. However, the country remains resource-rich, and its people have proven to be very resilient. More habitats are being protected and rehabilitated, and successful community-based fisheries management efforts are now being upscaled to higher governance levels. Although more conservation and management efforts are needed, there is much that could be learned from the Philippine experience. © 2019 Elsevier Ltd. All rights reserved

    Cooperative Pricing and Ordering Policies in a Two Stage Supply Chain System

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    Anti-Fungal Therapy in the ICU

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