RESTRICTED HOUSING AMONG JUVENILE POPULATIONS

Restricted housing among juvenile populations – the social and physical isolation of certain youth from other juveniles, recreational time, and educational materials – is a punitive method employed by juvenile correctional facilities that restricts youths’ physical movement for a prolonged period of time. Nebraska houses the third highest per capita number of juveniles residing in detention, correctional, or residential facilities in the United States, and many facilities across the state report using restricted housing for much longer period than surrounding states. Due to their age and associated developmental needs (e.g., brain development, social interactions, etc.), juveniles are at higher risk for experiencing negative effects of restricted housing, such as psychosis, suicidal ideation/attempts, depression, and anxiety. Further, the use of isolation may exacerbate existing mental and emotional problems among juveniles. Restricted housing is strongly linked to suicide attempts, in situations where juveniles are unattended and unmonitored. Moreover, juveniles in restricted housing are unable to access positive and prosocial activities or educational programming, and are thus “doubly punished” while in isolation. Due to the negative effects of restricted housing among juveniles, NCJR recommends the adoption of best practice standards for the use of restricted housing for juveniles in NDCS: 1) use restricted housing only as a temporary response to behavior that threatens immediate harm to the youth or others, 2) limit the time juveniles spend in restricted housing, and monitor them every 15 minutes, 3) prior to using restricted housing, staff should use less restrictive techniques and rehabilitative efforts, 4) explain the reasons for isolation to juveniles and the fact that they will be released upon regaining self-control, 5) assess youth at intake for mental health, suicide, or other risk factors that may be exacerbated by the use of restricted housing, 6) keep designated restricted housing areas suicide resistant and protrusion-free, 7) and better understand the unique developmental needs of juveniles so as to minimize the employment of tactics (such as restricted housing) that can negatively affect healthy development

Una arquitectura de referencia para ambientes web de ingeniería ontológica

Ontology authoring, maintenance and use are never easy tasks, mostly due to the complexity of real domains and how they dynamically change as well as different background possessed by modellers about methodologies and formal languages. However, although the needs for ontologies are well-understood, not less important is to provide editing tools to manipulate and understand them. In this context, this work proposes and documents a reference architecture for such tools running in web environments. Moreover, it provides the rationale for boosting the collaborative development of a novel tool based on this architecture, named crowd. Previous surveys reveal that few Webbased ontology engineering environments have been developed and in addition, almost all of them are mere visualisers, with limited graphical features and lacking inference services.La definición, mantenimiento y use de ontologías son tareas difíciles debido, en mayor medida, a la complejidad inherente al mundo real y a como éste cambia dinámicamente. Asimismo, también se debe a las diferencias en conocimiento sobre metodologías y lenguajes formales por parte de los modeladores. Sin embargo, aunque la necesidad de crear y obtener ontologías es clave, es también importante contar con herramientas para manipularlas y entenderlas. Este trabajo propone y documenta una arquitectura de referencia para ambientes Web y ofrece los fundamentos para impulsar el desarrollo colaborativo de la herramienta crowd, la cual esta basada sobre dicha architectura. Revisiones previas de la literatura indican la existencia de un numero reducido ambientes para la Ingeniería Ontológica basados en tecnologías Web, sin embargo, casi en su totalidad son solo visualizadores de modelos con soporte gráfico limitado y ausencia de razonamiento lógico integrado.Facultad de Informátic

Basel III C: Internal Risk Models

For financial regulators seeking to use regulatory requirements to manage risk in a banking system, there can be a concern that such requirements crowd out efforts by banks to develop their own risk management systems. One way in which regulators have attempted to solve this problem is to enable banks to use internal risk models to satisfy regulatory requirements. Beginning with the 1996 Market Risk Amendment, the Basel framework has allowed banks to determine the capital charges associated with certain assets using their own internal risk models. But allowing the use of internal risk models has not been without controversy. Where some see an incentive for the development of internal risk management systems better able to address the unique risk profiles of particular banks, others see excessive complexity and uncertainty. And while some financial regulators are beginning to subject banks’ models to greater scrutiny, questions remain about the ability of financial regulators to provide effective oversight of such models

Learning novel skills from iconic gestures : a developmental and evolutionary perspective

This research was supported by Horizon 2020 European Research Council Grant Nos. 609819 and 749229.Cumulative cultural learning has been argued to rely on high fidelity copying of others’ actions. Iconic gestures of actions have no physical effect on objects in the world but merely represent actions that would have an effect. Learning from iconic gestures thus requires paying close attention to the teacher’s precise bodily movements – a prerequisite for high fidelity copying. Three studies investigated whether 2- and 3-year-old children (N=122) and great apes (N=36) learn novel skills from iconic gestures. When faced with a novel apparatus, participants either watched an experimenter perform an iconic gesture depicting the action necessary to open the apparatus or a gesture depicting a different action. Children, but not great apes, profited from iconic gestures, with older children doing so to a larger extent. These results suggest that high fidelity copying abilities are firmly in place in humans by at least three years of age.PostprintPeer reviewe

Optimized RNA isolation of FFPE uterine scar tissues for RNA expression analyses delineated by laser microdissection

ABSTRACT Samples for histological analyses are often formalin-fixed paraffin-embedded (FFPE) and slide-mounted, which complicates RNA extraction for many downstream molecular applications. Furthermore, when the region of interest is extremely small due to isolation with lasermicrodissection (LMD), extracting RNA of adequate quality and quantity is difficult. We describe an optimized protocol for maximizing RNA output from FFPE tissue devised to identify and analyze gene expression of humanmaternal uterine scar tissue obtained fromuterotomy scars resulting from prior cesarean deliveries. Gomori trichrome staining allowed for region identification for LMD. Successful RNA isolation, reverse transcription and, importantly, quantitative real-time PCR (qRT-PCR) were performed. This report provides an optimized step-by-step protocol yielding sufficient RNA for qRT-PCR analyses from challenging tissue/LMD-FFPE samples. METHOD SUMMARY FFPE sample sections weremounted on glass slides and stained with hematoxylin and eosin (HE). A corresponding slide was stained according to Gomori trichrome for orientation. Regions of interest in HE-stained samples weremarked using lasermicrodissection (LMD) and subsequently scratched off the slide with a sterile scalpel. RNA extraction and cDNA synthesis were carried out, and quantitative real-time PCR with TaqMan probes was performed. TWEETABLE ABSTRACT We describe a protocol for maximized RNA output from FFPE tissue delineated by laser microdissection devised to analyze gene expression of human maternal uterine scar tissue obtained from uterotomy scars of prior cesarean deliveries

Una arquitectura de referencia para ambientes web de ingeniería ontológica

Ontology authoring, maintenance and use are never easy tasks, mostly due to the complexity of real domains and how they dynamically change as well as different background possessed by modellers about methodologies and formal languages. However, although the needs for ontologies are well-understood, not less important is to provide editing tools to manipulate and understand them. In this context, this work proposes and documents a reference architecture for such tools running in web environments. Moreover, it provides the rationale for boosting the collaborative development of a novel tool based on this architecture, named crowd. Previous surveys reveal that few Webbased ontology engineering environments have been developed and in addition, almost all of them are mere visualisers, with limited graphical features and lacking inference services.La definición, mantenimiento y use de ontologías son tareas difíciles debido, en mayor medida, a la complejidad inherente al mundo real y a como éste cambia dinámicamente. Asimismo, también se debe a las diferencias en conocimiento sobre metodologías y lenguajes formales por parte de los modeladores. Sin embargo, aunque la necesidad de crear y obtener ontologías es clave, es también importante contar con herramientas para manipularlas y entenderlas. Este trabajo propone y documenta una arquitectura de referencia para ambientes Web y ofrece los fundamentos para impulsar el desarrollo colaborativo de la herramienta crowd, la cual esta basada sobre dicha architectura. Revisiones previas de la literatura indican la existencia de un numero reducido ambientes para la Ingeniería Ontológica basados en tecnologías Web, sin embargo, casi en su totalidad son solo visualizadores de modelos con soporte gráfico limitado y ausencia de razonamiento lógico integrado.Facultad de Informátic

Faster Time to Treatment Decision of Viscoelastic Coagulation Test Results through Improved Perception with the Animated Visual Clot: A Multicenter Comparative Eye-Tracking Study

As the interpretation of viscoelastic coagulation test results remains challenging, we created Visual Clot, an animated blood clot aiming to facilitate raw rotational thromboelastometry (ROTEM) parameters. This study investigated anesthesia personnel's cognitive processing in managing simulated bleeding scenarios using eye-tracking technology. This multicenter, international, computer-based study across five large, central European hospitals included 35 participants with minimal to no prior experience interpreting viscoelastic test results. Using eye-tracking technology and an iPad tagged with quick response codes, we defined the time to treatment decision and the time on screen surface in seconds of correctly solved scenarios as our outcomes. The median time to treatment decision was 52 s for Visual Clot and 205 s for ROTEM (p < 0.0001). The probability of solving the scenario correctly was more than 8 times higher when using Visual Clot than when using ROTEM (Hazard ratio [HR] 8.54, 95% CI from 6.5 to 11.21; p < 0.0001). Out of 194 correctly answered scenarios of participants with the eye-tracker, 154 (79.4%) were solved with Visual Clot and 40 (20.6%) with ROTEM. Participants spent on average 30 s less looking at the screen surface with Visual Clot compared to ROTEM (Coefficient -30.74 s, 95% CI from -39.27 to -22.27; p < 0.0001). For a comparison of the two modalities in terms of information transfer, we calculated the percentage of time on the screen surface of the overall time to treatment decision, which with Visual Clot was 14 percentage points shorter than with ROTEM (Coefficient -14.55, 95% CI from -20.05 to -9.12; p < 0.0001). Visual Clot seems to improve perception and detection of coagulopathies and leads to earlier initiation of the appropriate treatment. In a high-pressure working environment such as the operating and the resuscitation room, correct and timely decisions regarding bleeding management may have a relevant impact on patients' outcomes. Keywords: Visual Clot; avatar; blood coagulation; eye-tracking; point-of-care; rotational thromboelastometry; viscoelastic test; visual perception

Spatial Variation in Throughfall, Soil, and Plant Water Isotopes in a Temperate Forest

Studies of stable isotopes of water in the environment have been fundamental to advancing our understanding of how water moves through the soil‐plant‐atmosphere continuum; however, much of this research focuses on how water isotopes vary in time, rather than in space. We examined the spatial variation in the δ18O and δ2H of throughfall and bulk soil water, as well as branch xylem and bulk leaf water of Picea abies (Norway Spruce) and Fagus sylvatica (Beech), in a 1 ha forest plot in the northern Alps of Switzerland. Means and ranges of water isotope ratios varied considerably among throughfall, soil, and xylem samples. Soil water isotope ratios were often poorly explained by soil characteristics and often not predictable from proximal samples. Branch xylem water isotope values varied less than either soil water or bulk leaf water. The isotopic range observed within an individual tree crown was often similar to that observed among different crowns. As a result of the heterogeneity in isotope ratios, inferences about the depth of plant root water uptake drawn from a two end‐member mixing model were highly sensitive to the soil sampling location. Our results clearly demonstrate that studies using water isotopes to infer root water uptake must explicitly consider how to characterize soil water, incorporating measures of both vertical and lateral variation. By accounting for this spatial variation and the processes that shape it, we can improve the application of water isotopes to studies of plant ecophysiology, ecohydrology, soil hydrology, and paleoclimatology

Improved Task Performance, Low Workload, and User-Centered Design in Medical Diagnostic Equipment Enhance Decision Confidence of Anesthesia Providers: A Meta-Analysis and a Multicenter Online Survey

Decision confidence-the subjective belief to have made the right decision-is central in planning actions in a complex environment such as the medical field. It is unclear by which factors it is influenced. We analyzed a pooled data set of eight studies and performed a multicenter online survey assessing anesthesiologists' opinions on decision confidence. By applying mixed models and using multiple imputation to determine the effect of missing values from the dataset on the results, we investigated how task performance, perceived workload, the utilization of user-centered medical diagnostic devices, job, work experience, and gender affected decision confidence. The odds of being confident increased with better task performance (OR: 1.27, 95% CI: 0.94 to 1.7; p = 0.12; after multiple imputation OR: 3.19, 95% CI: 2.29 to 4.45; p < 0.001) and when user-centered medical devices were used (OR: 5.01, 95% CI: 3.67 to 6.85; p < 0.001; after multiple imputation OR: 3.58, 95% CI: 2.65 to 4.85; p < 0.001). The odds of being confident decreased with higher perceived workload (OR: 0.94, 95% CI: 0.93 to 0.95; p < 0.001; after multiple imputation, OR: 0.94, 95% CI: 0.93 to 0.95; p < 0.001). Other factors, such as gender, job, or professional experience, did not affect decision confidence. Most anesthesiologists who participated in the online survey agreed that task performance (25 of 30; 83%), perceived workload (24 of 30; 80%), work experience (28 of 30; 93%), and job (21 of 30; 70%) influence decision confidence. Improved task performance, lower perceived workload, and user-centered design in medical equipment enhanced the decision confidence of anesthesia providers. Keywords: diagnostic; diagnostic confidence; gender; online survey; over-confidence; self-assessment; under-confidence; user-centered design; workloa

Improved Task Performance, Low Workload, and User-Centered Design in Medical Diagnostic Equipment Enhance Decision Confidence of Anesthesia Providers: A Meta-Analysis and a Multicenter Online Survey

Decision confidence-the subjective belief to have made the right decision-is central in planning actions in a complex environment such as the medical field. It is unclear by which factors it is influenced. We analyzed a pooled data set of eight studies and performed a multicenter online survey assessing anesthesiologists' opinions on decision confidence. By applying mixed models and using multiple imputation to determine the effect of missing values from the dataset on the results, we investigated how task performance, perceived workload, the utilization of user-centered medical diagnostic devices, job, work experience, and gender affected decision confidence. The odds of being confident increased with better task performance (OR: 1.27, 95% CI: 0.94 to 1.7; p = 0.12; after multiple imputation OR: 3.19, 95% CI: 2.29 to 4.45; p < 0.001) and when user-centered medical devices were used (OR: 5.01, 95% CI: 3.67 to 6.85; p < 0.001; after multiple imputation OR: 3.58, 95% CI: 2.65 to 4.85; p < 0.001). The odds of being confident decreased with higher perceived workload (OR: 0.94, 95% CI: 0.93 to 0.95; p < 0.001; after multiple imputation, OR: 0.94, 95% CI: 0.93 to 0.95; p < 0.001). Other factors, such as gender, job, or professional experience, did not affect decision confidence. Most anesthesiologists who participated in the online survey agreed that task performance (25 of 30; 83%), perceived workload (24 of 30; 80%), work experience (28 of 30; 93%), and job (21 of 30; 70%) influence decision confidence. Improved task performance, lower perceived workload, and user-centered design in medical equipment enhanced the decision confidence of anesthesia providers. Keywords: diagnostic; diagnostic confidence; gender; online survey; over-confidence; self-assessment; under-confidence; user-centered design; workloa