144 research outputs found
First measurements of 15N fractionation in N2H+ toward high-mass star forming cores
We report on the first measurements of the isotopic ratio 14N/15N in N2H+
toward a statistically significant sample of high-mass star forming cores. The
sources belong to the three main evolutionary categories of the high-mass star
formation process: high-mass starless cores, high-mass protostellar objects,
and ultracompact HII regions. Simultaneous measurements of 14N/15N in CN have
been made. The 14N/15N ratios derived from N2H+ show a large spread (from ~180
up to ~1300), while those derived from CN are in between the value measured in
the terrestrial atmosphere (~270) and that of the proto-Solar nebula (~440) for
the large majority of the sources within the errors. However, this different
spread might be due to the fact that the sources detected in the N2H+
isotopologues are more than those detected in the CN ones. The 14N/15N ratio
does not change significantly with the source evolutionary stage, which
indicates that time seems to be irrelevant for the fractionation of nitrogen.
We also find a possible anticorrelation between the 14N/15N (as derived from
N2H+) and the H/D isotopic ratios. This suggests that 15N enrichment could not
be linked to the parameters that cause D enrichment, in agreement with the
prediction by recent chemical models. These models, however, are not able to
reproduce the observed large spread in 14N/15N, pointing out that some
important routes of nitrogen fractionation could be still missing in the
models.Comment: 2 Figures, accepted for publication in ApJ
Kinematics of dense gas in the L1495 filament
We study the kinematics of the dense gas of starless and protostellar cores
traced by the N2D+(2-1), N2H+(1-0), DCO+(2-1), and H13CO+(1-0) transitions
along the L1495 filament and the kinematic links between the cores and the
surrounding molecular cloud.
We measure velocity dispersions, local and total velocity gradients and
estimate the specific angular momenta of 13 dense cores in the four transitions
using the on-the-fly observations with the IRAM 30 m antenna. To study a
possible connection to the filament gas, we use the fit results of the
C18O(1-0) survey performed by Hacar et al. (2013).
All cores show similar properties along the 10 pc-long filament. N2D+(2-1)
shows the most centrally concentrated structure, followed by N2H+(1-0) and
DCO+(2-1), which show similar spatial extent, and H13CO+(1-0). The non-thermal
contribution to the velocity dispersion increases from higher to lower density
tracers. The change of magnitude and direction of the total velocity gradients
depending on the tracer used indicates that internal motions change at
different depths within the cloud. N2D+ and N2H+ show smaller gradients than
the lower density tracers DCO+ and H13CO+, implying a loss of specific angular
momentum at small scales. At the level of cloud-core transition, the core's
external envelope traced by DCO+ and H13CO+ is spinning up, consistent with
conservation of angular momentum during core contraction. C18O traces the more
extended cloud material whose kinematics is not affected by the presence of
dense cores. The decrease in specific angular momentum towards the centres of
the cores shows the importance of local magnetic fields to the small scale
dynamics of the cores. The random distributions of angles between the total
velocity gradient and large scale magnetic field suggests that the magnetic
fields may become important only in the high density gas within dense cores.Comment: Accepted for publication in A&A. The abstract is shortene
O2 signature in thin and thick O2-H2O ices
Aims. In this paper we investigate the detectability of the molecular oxygen
in icy dust grain mantles towards astronomical objects. Methods. We present a
systematic set of experiments with O2-H2O ice mixtures designed to disentangle
how the molecular ratio affects the O2 signature in the mid- and near-infrared
spectral regions. All the experiments were conducted in a closed-cycle helium
cryostat coupled to a Fourier transform infrared spectrometer. The ice mixtures
comprise varying thicknesses from 8 10 to 3 m. The
absorption spectra of the O2-H2O mixtures are also compared to the one of pure
water. In addition, the possibility to detect the O2 in icy bodies and in the
interstellar medium is discussed. Results. We are able to see the O2 feature at
1551 cm even for the most diluted mixture of H2O : O2 = 9 : 1,
comparable to a ratio of O2/H2O = 10 % which has already been detected in situ
in the coma of the comet 67P/Churyumov-Gerasimenko. We provide an estimate for
the detection of O2 with the future mission of the James Webb Space Telescope
(JWST).Comment: 11 pages, 10 figures, article in press, to appear in A&A 201
The chemical structure of the very young starless core L1521E
L1521E is a dense starless core in Taurus that was found to have relatively
low molecular depletion by earlier studies, thus suggesting a recent formation.
We aim to characterize the chemical structure of L1521E and compare it to the
more evolved L1544 pre-stellar core. We have obtained 2.52.5
arcminute maps toward L1521E using the IRAM-30m telescope in transitions of
various species. We derived abundances for the species and compared them to
those obtained toward L1544. We estimated CO depletion factors. Similarly to
L1544, -CH and CHOH peak at different positions. Most species
peak toward the -CH peak. The CO depletion factor derived toward the
dust peak is 4.31.6, which is about a factor of three lower
than that toward L1544. The abundances of sulfur-bearing molecules are higher
toward L1521E than toward L1544 by factors of 2-20. The abundance of
methanol is similar toward the two cores. The higher abundances of
sulfur-bearing species toward L1521E than toward L1544 suggest that significant
sulfur depletion takes place during the dynamical evolution of dense cores,
from the starless to pre-stellar stage. The CO depletion factor measured toward
L1521E suggests that CO is more depleted than previously found. Similar
CHOH abundances between L1521E and L1544 hint that methanol is forming at
specific physical conditions in Taurus, characterized by densities of a few
10 cm and (H)10 cm, when CO
starts to catastrophically freeze-out, while water can still be significantly
photodissociated, so that the surfaces of dust grains become rich in solid CO
and CHOH, as already found toward L1544. Methanol can thus provide
selective crucial information about the transition region between dense cores
and the surrounding parent cloud.Comment: Accepted for publication in A&A, abstract abridge
A study of the -/- ratio in low-mass star forming regions
We use the deuteration of - to probe the physical
parameters of starless and protostellar cores, related to their evolutionary
states, and compare it to the -deuteration in order to
study possible differences between the deuteration of C- and N-bearing species.
We observed the main species -, the singly and doubly
deuterated species - and -, as
well as the isotopologue - toward 10 starless
cores and 5 protostars in the Taurus and Perseus Complexes. We examined the
correlation between the
(-)/(-) ratio and the dust
temperature along with the column density and the CO depletion
factor. The resulting
(-)/(-) ratio is within the
error bars consistent with in all starless cores with detected
-. This also accounts for the protostars except for the
source HH211, where we measure a high deuteration level of . The
deuteration of follows the same trend but is considerably
higher in the dynamically evolved core L1544. Toward the protostellar cores the
coolest objects show the largest deuterium fraction in
-. We show that the deuteration of
- can trace the early phases of star formation and is
comparable to that of . However, the largest
- deuteration level is found toward protostellar cores,
suggesting that while - is mainly frozen onto dust
grains in the central regions of starless cores, active deuteration is taking
place on ice
Rotational spectroscopy of the HCCO and DCCO radicals in the millimeter and submillimeter range
The ketenyl radical, HCCO, has recently been detected in the ISM for the
first time. Further astronomical detections of HCCO will help us understand its
gas-grain chemistry, and subsequently revise the oxygen-bearing chemistry
towards dark clouds. Moreover, its deuterated counterpart, DCCO, has never been
observed in the ISM. HCCO and DCCO still lack a broad spectroscopic
investigation, although they exhibit a significant astrophysical relevance. In
this work we aim to measure the pure rotational spectra of the ground state of
HCCO and DCCO in the millimeter and submillimeter region, considerably
extending the frequency range covered by previous studies. The spectral
acquisition was performed using a frequency-modulation absorption spectrometer
between 170 and 650 GHz. The radicals were produced in a low-density plasma
generated from a select mixture of gaseous precursors. For each isotopologue we
were able to detect and assign more than 100 rotational lines. The new lines
have significantly enhanced the previous data set allowing the determination of
highly precise rotational and centrifugal distortion parameters. In our
analysis we have taken into account the interaction between the ground
electronic state and a low-lying excited state (Renner-Teller pair) which
enables the prediction and assignment of rotational transitions with up
to 4. The present set of spectroscopic parameters provides highly accurate,
millimeter and submillimeter rest-frequencies of HCCO and DCCO for future
astronomical observations. We also show that towards the pre-stellar core
L1544, ketenyl peaks in the region where - peaks,
suggesting that HCCO follows a predominant hydrocarbon chemistry, as already
proposed by recent gas-grain chemical models
Search for grain growth towards the center of L1544
In dense and cold molecular clouds dust grains are surrounded by thick icy
mantles. It is however not clear if dust growth and coagulation take place
before the switch-on of a protostar. This is an important issue, as the
presence of large grains may affect the chemical structure of dense cloud
cores, including the dynamically important ionization fraction, and the future
evolution of solids in protoplanetary disks. To study this further, we focus on
L1544, one of the most centrally concentrated pre-stellar cores on the verge of
star formation, and with a well-known physical structure. We observed L1544 at
1.2 and 2 mm using NIKA, a new receiver at the IRAM 30 m telescope, and we used
data from the Herschel Space Observatory archive. We find no evidence of grain
growth towards the center of L1544 at the available angular resolution.
Therefore, we conclude that single dish observations do not allow us to
investigate grain growth toward the pre-stellar core L1544 and high sensitivity
interferometer observations are needed. We predict that dust grains can grow to
200 m in size toward the central ~300 au of L1544. This will imply a dust
opacity change by a factor of ~2.5 at 1.2 mm, which can be detected using the
Atacama Large Millimeter and submillimeter Array (ALMA) at different
wavelengths and with an angular resolution of 2".Comment: 12 pages, 14 figures. Accepted for publication in A&
Mapping deuterated methanol toward L1544: I. Deuterium fraction and comparison with modeling
The study of deuteration in pre-stellar cores is important to understand the
physical and chemical initial conditions in the process of star formation. In
particular, observations toward pre-stellar cores of methanol and deuterated
methanol, solely formed on the surface of dust grains, may provide useful
insights on surface processes at low temperatures. Here we analyze maps of CO,
methanol, formaldehyde and their deuterated isotopologues toward a well-known
pre-stellar core. This study allows us to test current gas-dust chemical
models. Single-dish observations of CHOH, CHDOH, HCO,
H_2\,^{13}CO, HDCO, DCO and CO toward the prototypical pre-stellar
core L1544 were performed at the IRAM 30 m telescope. We analyze their column
densities, distributions, and compare these observations with gas-grain
chemical models. The maximum deuterium fraction derived for methanol is
[CHDOH]/[CHOH] 0.080.02, while the measured deuterium
fractions of formaldehyde at the dust peak are [HDCO]/[HCO]
0.030.02, [DCO]/[HCO] 0.040.03 and [DCO]/[HDCO]
1.20.3. Observations differ significantly from the predictions of
models, finding discrepancies between a factor of 10 and a factor of 100 in
most cases. It is clear though that to efficiently produce methanol on the
surface of dust grains, quantum tunneling diffusion of H atoms must be switched
on. It also appears that the currently adopted reactive desorption efficiency
of methanol is overestimated and/or that abstraction reactions play an
important role. More laboratory work is needed to shed light on the chemistry
of methanol, an important precursor of complex organic molecules in space.Comment: Accepted for publication in A&
The impact of organ motion and the appliance of mitigation strategies on the effectiveness of hypoxia-guided proton therapy for non-small cell lung cancer.
BACKGROUND AND PURPOSE
To investigate the impact of organ motion on hypoxia-guided proton therapy treatments for non-small cell lung cancer (NSCLC) patients.
MATERIALS AND METHODS
Hypoxia PET and 4D imaging data of six NSCLC patients were used to simulate hypoxia-guided proton therapy with different motion mitigation strategies including rescanning, breath-hold, respiratory gating and tumour tracking. Motion-induced dose degradation was estimated for treatment plans with dose painting of hypoxic tumour sub-volumes at escalated dose levels. Tumour control probability (TCP) and dosimetry indices were assessed to weigh the clinical benefit of dose escalation and motion mitigation. In addition, the difference in normal tissue complication probability (NTCP) between escalated proton and photon VMAT treatments have been assessed.
RESULTS
Motion-induced dose degradation was found for target coverage (CTV V95% up to -4%) and quality of the dose-escalation-by-contour (QRMS up to 6%) as a function of motion amplitude and amount of dose escalation. The TCP benefit coming from dose escalation (+4-13%) outweighs the motion-induced losses (<2%). Significant average NTCP reductions of dose-escalated proton plans were found for lungs (-14%), oesophagus (-10%) and heart (-16%) compared to conventional VMAT plans. The best plan dosimetry was obtained with breath hold and respiratory gating with rescanning.
CONCLUSION
NSCLC affected by hypoxia appears to be a prime target for proton therapy which, by dose-escalation, allows to mitigate hypoxia-induced radio-resistance despite the sensitivity to organ motion. Furthermore, substantial reduction in normal tissue toxicity can be expected compared to conventional VMAT. Accessibility and standardization of hypoxia imaging and clinical trials are necessary to confirm these findings in a clinical setting
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