7,230 research outputs found

    Optimizing the computation of overriding

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    We introduce optimization techniques for reasoning in DLN---a recently introduced family of nonmonotonic description logics whose characterizing features appear well-suited to model the applicative examples naturally arising in biomedical domains and semantic web access control policies. Such optimizations are validated experimentally on large KBs with more than 30K axioms. Speedups exceed 1 order of magnitude. For the first time, response times compatible with real-time reasoning are obtained with nonmonotonic KBs of this size

    The possible effect of the bioaccumulation of disinfectant by-products on crops irrigated with treated wastewater

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    The shortage of potable water for irrigation of food crops in semi-arid developing countries led to the use of alternative sources of water. Wastewater is gaining importance for productive use in agriculturethroughout the world. A widely used and efficient method to reduce the occurrence of waterborne diseases in numerous wastewater plants is water chlorination. In early 1970s, some volatile halogenated organic compounds such as chloroform were identified in chlorinated surface waters containing high levels of natural organic material. Generally, the trihalomethanes (THMs), including chloroform, bromodicholoromethane, dibromochloromethane and bromoform were the most prevalent in chlorinated surface water. Predominant research studies focused on the carcinogenic and mutagenic properties of these compounds in treated wastewater. But little attention was paid to how these compounds in treatedwastewater could affect crop performance in agriculture, physiological changes amongst crop varieties and the build-up of these organic compounds in edible plant tissues with persistent use of treated waste-water. A probable reason for this was the absence of the practice of wastewater irrigation in food crop agriculture in the past. Current knowledge on the trihalomethanes and possible plant interactions with this group of volatile organic compounds are assessed in this review

    Clinical effectiveness of a rehabilitation program integrating exercise, self-management, and active coping strategies for chronic knee pain: a cluster randomized trial.

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    OBJECTIVE: Chronic knee pain is a major cause of disability and health care expenditure, but there are concerns about efficacy, cost, and side effects associated with usual primary care. Conservative rehabilitation may offer a safe, effective, affordable alternative. We compared the effectiveness of a rehabilitation program integrating exercise, self-management, and active coping strategies (Enabling Self-management and Coping with Arthritic Knee Pain through Exercise [ESCAPE-knee pain]) with usual primary care in improving functioning in persons with chronic knee pain. METHODS: We conducted a single-blind, pragmatic, cluster randomized controlled trial. Participants age >/=50 years, reporting knee pain for >6 months, were recruited from 54 inner-city primary care practices. Primary care practices were randomized to continued usual primary care (i.e., whatever intervention a participant's primary care physician deemed appropriate), usual primary care plus the rehabilitation program delivered to individual participants, or usual primary care plus the rehabilitation program delivered to groups of 8 participants. The primary outcome was self-reported functioning (Western Ontario and McMaster Universities Osteoarthritis Index physical functioning [WOMAC-func]) 6 months after completing rehabilitation. RESULTS: A total of 418 participants were recruited; 76 (18%) withdrew, only 5 (1%) due to adverse events. Rehabilitated participants had better functioning than participants continuing usual primary care (-3.33 difference in WOMAC-func score; 95% confidence interval [95% CI] -5.88, -0.78; P = 0.01). Improvements were similar whether participants received individual rehabilitation (-3.53; 95% CI -6.52, -0.55) or group rehabilitation (-3.16; 95% CI -6.55, -0.12). CONCLUSION: ESCAPE-knee pain provides a safe, relatively brief intervention for chronic knee pain that is equally effective whether delivered to individuals or groups of participants

    Computing Compliant Anonymisations of Quantified ABoxes w.r.t. EL Policies

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    We adapt existing approaches for privacy-preserving publishing of linked data to a setting where the data are given as Description Logic (DL) ABoxes with possibly anonymised (formally: existentially quantified) individuals and the privacy policies are expressed using sets of concepts of the DL EL. We provide a chacterization of compliance of such ABoxes w.r.t. EL policies, and show how optimal compliant anonymisations of ABoxes that are non-compliant can be computed. This work extends previous work on privacy-preserving ontology publishing, in which a very restricted form of ABoxes, called instance stores, had been considered, but restricts the attention to compliance. The approach developed here can easily be adapted to the problem of computing optimal repairs of quantified ABoxes

    The Big Opportunity: Advancing a Culture of Interprofessionalism

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    Historically, education has been siloed by disciplines leaving little room for interprofessional education to take place. Culture within an academic organization determines the strategies, modes of operation, goals, values, and terminal student learning outcomes. Using Kotter’s accelerated change management model, as a worksheet for educational cultural change, is an effective method to break complacency, generate ideas, align people, and overcome resistance to change

    Symptoms and Surgical Management of a Distal Choledochal Cyst in a Patient with Pancreas Divisum: Case Report and Review of the Literature

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    We report the case of a 63-year-old woman who presented with the rare finding of a distal choledochocele in a pancreas divisum with recurrent abdominal pain and episodes of pancreatitis. She underwent successful resection with choledochectomy, papillectomy and reconstruction with a hepatico-jejunostomy and reinsertion of the uncinate pancreatic duct into the same jejunal loop. Comparable literature findings are discussed with regard to the presented case

    Foot pain and foot health in an educated population of adults: results from the Glasgow Caledonian University Alumni Foot Health Survey

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    Abstract Background Foot pain is common amongst the general population and impacts negatively on physical function and quality of life. Associations between personal health characteristics, lifestyle/behaviour factors and foot pain have been studied; however, the role of wider determinants of health on foot pain have received relatively little attention. Objectives of this study are i) to describe foot pain and foot health characteristics in an educated population of adults; ii) to explore associations between moderate-to-severe foot pain and a variety of factors including gender, age, medical conditions/co-morbidity/multi-morbidity, key indicators of general health, foot pathologies, and social determinants of health; and iii) to evaluate associations between moderate-to-severe foot pain and foot function, foot health and health-related quality-of-life. Methods Between February and March 2018, Glasgow Caledonian University Alumni with a working email address were invited to participate in the cross-sectional electronic survey (anonymously) by email via the Glasgow Caledonian University Alumni Office. The survey was constructed using the REDCap secure web online survey application and sought information on presence/absence of moderate-to-severe foot pain, patient characteristics (age, body mass index, socioeconomic status, occupation class, comorbidities, and foot pathologies). Prevalence data were expressed as absolute frequencies and percentages. Multivariate logistic and linear regressions were undertaken to identify associations 1) between independent variables and moderate-to-severe foot pain, and 2) between moderate-to-severe foot pain and foot function, foot health and health-related quality of life. Results Of 50,228 invitations distributed, there were 7707 unique views and 593 valid completions (median age [inter-quartile range] 42 [31–52], 67.3% female) of the survey (7.7% response rate). The sample was comprised predominantly of white Scottish/British (89.4%) working age adults (95%), the majority of whom were overweight or obese (57.9%), and in either full-time or part-time employment (82.5%) as professionals (72.5%). Over two-thirds (68.5%) of the sample were classified in the highest 6 deciles (most affluent) of social deprivation. Moderate-to-severe foot pain affected 236/593 respondents (39.8%). High body mass index, presence of bunions, back pain, rheumatoid arthritis, hip pain and lower occupation class were included in the final multivariate model and all were significantly and independently associated with moderate-to-severe foot pain (p < 0.05), except for rheumatoid arthritis (p = 0.057). Moderate-to-severe foot pain was significantly and independently associated lower foot function, foot health and health-related quality of life scores following adjustment for age, gender and body mass index (p < 0.05). Conclusions Moderate-to-severe foot pain was highly prevalent in a university-educated population and was independently associated with female gender, high body mass index, bunions, back pain, hip pain and lower occupational class. Presence of moderate-to-severe foot pain was associated with worse scores for foot function, foot health and health-related quality-of-life. Education attainment does not appear to be protective against moderate-to-severe foot pain
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