Etude Par Fragmentographie de Masse de la Cinetique Sanguine D'un Anti-Inflammatoire DU F-1594

Sari. Telah dilakukan penetapan kadar plasmatik dari senyawa p bifenil-4, okso-4, metil-2-butirat (F-1594) sebagai salah satu obat anti inflamasi dengan teknik kombinasi kromatografi gas-spektrometri massa. F-1594 dengan 'internal standar' p-bifenil 4-chloro 2' asetat diekstraksi dari plasma, dipisahkan melalui kromatografi gas yang dilengkapi dengan kolom kapiler kemudian dianalisa secara fragmentografi massa. Dengan menggunakan sedikit cuplikan, cara ini mampu mendeteksi suatu sediaan dengan konsentrasi yang sangat kecil. Abstract. The determination of p-biphenyl-4, oxo-4, methyl-2-butyric acid (F-1594) as an antiinflammatory agent in the human plasma by using gas chromatography-mass spectrometry is described. Quantitation was achieved after extraction from the plasma, F 1594 and p-biphenyl 4-chloro 2'-acetic acid as an internal standard, separated by gas chromatography with the capillary column and analysed by mass fragmentography. This process requires only a very little sample and it enables the detection of very low concentration

The effect of laser irradiation on the viability of human breast cancer cell, MDA-MB-231

A practical pass-through type fibre Bragg grating (FBG) temperature sensor system have been designed, developed, simulated, and experimentally investigated. The performance of FBG was evaluated in harsh environments exposed under direct sunlight, rain, and wind. The sensor system designed directly focused with convex and hand lens. The temperature of FBG’s sensor head been measured. The broadband laser source was launched into the system using tunable laser source (TLS) and both transmission and reflection spectra of FBG sensor were measured by optical spectrum analyzer (OSA). Results shows that the Bragg wavelength shift, ΔλB increased proportionally with the temperature changes. The sensitivity of FBG were recorded at 0.0100 and 0.0132 nm °C-1 for the systems where convex and hand lens applied to the FBG’s sensor head respectively, while the sensitivity of 0.0118 nm °C-1 measured for the system without any focusing element applied

Analisis Fabrikasi Desain Lamination Passive Mixing Microchannel Perangkat Mikrofluidik AcrylicMenggunakan Laser CO Daya Rendah

Microfluidics device has been applied in the biomedical fields to manipulate fluids in a channel network with the dimensions between 5-500 µm. Microfluidics device is manufactured by microfabrication process consists ofdesign, microstucturing and back-end process. One of microfluidics application is passive mixing microchannel. Inthis device, the fluids will flow through the channel without any moving part and pressure from outside to producemixing fluid. It is important to design the form of channel to produce a good lamination passive mixingmicrochannel. In this study, the process of channel design was performed. Low power CO2 laser was used formicrostucturing process as a cutting tool to produce microfluidic device on acrylic material. The parameters affectthe output of the cutting process are the laser power, cutting speed and the design of channel. Surface roughness ofdesigned channel was observed. Finally, back-end process was performed by joining process using thermalbonding method. From the experimental results, the design of lamination channel has an influence on allparameters to the surface roughnes

Design and Build Automatic Cracker Machine Control System Based PLC-Pneumatic

Onion crackers are snacks categorized as crackers as complementary foods for the Indonesian people. Crackers are snacks that have a thin, round, and light shape. The process of packaging crackers is partially and fully manually done by humans. Packaging is representative of product quality. The packaging sealing process is influenced by pressure, temperature, and time. The method used in this study is to design and build a control system and test the results of the manufacture, where the control is made based on PLC with CX-Programer software which the system control integrated with HMI made with CX-Designer software. The control system is designed to drive the AC motor of the dosing system, the Dc motor of the packaging puller system, and the vertical and pneumatic heating system on the horizontal sealer system. The control system is made and tested for the function of the I / O program, and the overall control system that has been made works well

Removal of Arsenic (III) from groundwater applying a reusable Mg-Fe-Cl layered double hydroxide

BACKGROUND: Layered double hydroxide compounds (LDHs) have been applied for the removal of oxyanions including arsenate (As(V)). However, the aim of this present research is to develop a LDH to treat arsenite (As(III)). Both batch and column sorption studies were conducted to assess the effect of LDH dosage, contact time, solution pH and initial As(III) concentrations on the As(III) removal performance. The potential re-use of this sorbent was also investigated.<p></p> RESULTS: For 2 g L−1 of Mg-Fe-Cl LDH, As(III) in test solution can be reduced from 400 µg L−1 to <10 µg L−1 after a contact time of 2 h. High As(III) concentration in Bangladesh groundwater can be reduced to meet the national drinking water standards (<50 µg L−1). The maximum adsorption capacity of As(III) by Mg-Fe-Cl LDH is 14.6 mg g−1-LDH. Further, reusability of this sorbent was at least 20 cycles of regeneration with effective As(III) removal between 93.0 and 98.5%. Moreover, As(III) removal was unaffected by the solution pH but affected by the co-existing competing anions and concentration of As(III). Finally, the main mechanism of As(III) removal by Mg-Fe-Cl LDH was suggested to be chemical sorption together with anion and ligand exchange with interlayer Cl− and OH− ions.<p></p> CONCLUSION: High efficiency of sorption of As(III) by the developed Mg-Fe-Cl LDH was demonstrated in this study which is generally not the case for most other sorbent materials. Pilot-scale trials are needed to explore the suitability of full application of the developed Mg-Fe-Cl LDH for the removal of As(III).<p></p&gt

Simple procedure for determining implications of design changes on fast reactor fuel cycle cost and breeding performance

Recently, analytical sensitivity methods has been applied to obtain fuel cycle cost implications of data uncertainties. To perform exposure dependent sensitivity analysis without repeating expensive spectrum calculations, simple correlations of the spectrum averaged cross sections (SAXS) were constructed. The correlation coefficients were obtained by fitting the SAXS calculated by direct methods over a wide range of LMFBR core designs. In this paper the procedure has been extended to study sensitivity of fuel cycle cost and breeding ratio to design variation. The method involves using the correlations to construct both the SAXS and the sensitivity coefficients. Composition dependent correlations have been found to be accurate for the core while both composition and position have to be included in analysing the blanket

Kajian Kualitas Kascing pada Vermicomposting dari Campuran Feses Sapi Perah dan Jerami Padi (Casting quality assesment on vermicomposting of mixed feces of dairy cattle and rice straw )

Penelitian ini bertujuan untuk mengetahui pengaruh campuran Feses Sapi Perah dan Jerami padi dalam Vermicomposting terhadap kualitas kascing   (kandungan N,P,K,Ca,Mg,KTK). Metode yang digunakan dalam penelitian ini adalah metode eksperimen di laboratorium dengan menggunakan Rancangan Acak Lengkap dengan 3 perlakuan dan 6 kali ulangan,  sehingga diperoleh 18 sampel perlakuan.  Ketiga perlakuan tersebut, adalah P1 = C/N 25; P2 =  C/N 30; P3=  C/N 35. Data dianalisis dengan menggunakan sidik ragam dan untuk mengetahui perbedaanantar perlakuan dilakukan uji Duncan. Hasil penelitian menunjukkan bahwa Campuran Feses Sapi Perah dan Jerami Padi dalam Vermicomposting dengan nisbah C/N rasio 25 - 35 menghasilkan kualitas kascing yang optimum yaitu kandungan N 1,38 – 2,12   %,P2O50,72 –1,61%, K2O 0,54 – 0,93%, Ca+ 0,80 – 1,24%, Mg+ 0,98 – 1,21%, dan Nilai KTK 0,84,86 –0,85 -17cmol/kg.Kata Kunci: feses sapi perah, jerami padi, vermicomposting, kascin

Pengujian variasi jumlah blade fiberglass kincir angin type horizontal untuk pemompa air garam

Faktor manajemen proses pembuatan garam perlu dipertimbangkan pemilihan lokasi dan musim sangat penting untuk mendukung upaya pengasinan air garam. Kincir angin yang dimiliki oleh petani masih menggunakan material kayu yang dibuat setiap tahun itu tidak efektif dilakukan dan bentuk kincir angin yang dibuat tidak sesuai dengan persyaratan tanpa mempertimbangkan kecepatan angin. Kontrol kecepatan pemompaan dipengaruhi oleh ukuran, berat dan variasi jumlah Blade serta ukuran kincir angin yang mempengaruhi produktivitas garam, untuk mengoptimalkan fungsi kincir angin pemompa air garam dengan mengubah material Blade pada kincir angin dengan menggunakan material komposit dan mengubah variasi jumlah Blade pada kincir angin dengan jumlah Blade 2,3,4 dan 6.Hasil pengujian menggunakan blower (fan) menunjukan bahwa pompa yang akan terangkat penuh hanya pada variasi jumlah Blade 3, 4 dan 6 dengan kecepatan 3,49 m/s. Sedangkan untuk hasil koefisien daya, semakin banyak jumlah Blade maka semakin besar efisiensi daya yang dihasilkan. Sehingga dari hasil simulasi dan uji lab maka penulis merekomendasikan variasi jumlah Blade 3,4 dan 6. Namun kenyataan pengujian di lab untuk variasi jumlah Blade 6 memerlukan kecepatan yang tinggi untuk awal memutarkan Blade, jadi Blade 4 yang paling direkomendasikan

Arsenic mitigation: water quality of dug wells and tubewells

Arsenic concentration in very shallow and deep aquifers is comparatively lower than shallow aquifers in arsenic contaminated areas. As a result, dug wells and deep tubewells have emerged as two major water supply options for populations exposed to high levels of arsenic through drinking contaminated shallow tubewell water in Bangladesh and West Bengal (India). The concentrations of other impurities of health concern also vary with depth and other characteristics of the aquifer. Hence, shifting from one source to another may be the cause of exposure to health risk of a different nature. This paper presents an assessment of water quality of dug wells (DW) and deep tubewells (DTW) as compared to shallow tubewells (STW) for water supply. The results show that a shift from STW to DW reduces median arsenic ingestion from 151 μg/L (Mean 172μg/L) to 0.74 μg/L(mean 7.92μg/L), while DTW further reduces median arsenic ingestion to 0.41μg/L (mean 1.05μg/L). On the other hand, microbial contamination indicated by median value of Thermotolerant Coliform (TTC) count was found to be 48 cfu/100ml for DW water as compared to 0 cfu/100ml for both STW and DTW waters