To Fib or Not to Fib: Misdiagnosis of Atrial Fibrillation on Telemetry Case Presentation and Root Cause Analysis

Case presentation, current practices of telemetry management, root cause analysis, goals for improvement, proposed intervention and next steps

Multi-lepton signals from the top-prime quark at the LHC

We analyze the collider signatures of models with a vector-like top-prime quark and a massive color-octet boson. The top-prime quark mixes with the top quark in the Standard Model, leading to richer final states than ones that are investigated by experimental collaborations. We discuss the multi-lepton final states, and show that they can provide increased sensitivity to models with a top-prime quark and gluon-prime. Searches for new physics in high multiplicity events are an important component of the LHC program and complementary to analyses that have been performed.Comment: 7 pages, 4 figures, 2 table

Bridging the gap: Increasing awareness of sex differences in opioid addiction using social media platforms

HONORABLE MENTION Background: Current efforts to combat the opioid epidemic in the United States do not take into account the sex differences in opioid response, prescription, use, and addiction. There is a need for medical professionals and the general public to understand these differences to properly prevent, address, and treat opioid addiction. Healthcare professionals and patients often use the Internet and social networking websites to access and share medical information. These platforms provide an innovative way to educate these groups on various topics in medicine. The American Medical Women’s Association (AMWA) created the Opioid Addiction in Women Task Force to positively impact care for women with opioid addiction. Objectives: Increase health literacy surrounding sex differences in opioid addiction in the general public and healthcare providers via social media platforms Methods/Research: The AMWA Opioid Task Force consists of physicians and medical students across the country who meet virtually each month. With guidance from supervising physicians, educational infographics, pamphlets, and videos are created to facilitate the dissemination of complex scientiffc data in a simple and engaging manner. Information is subsequently shared via social media platforms, such as Instagram, Twitter and YouTube, where they can be easily accessed by healthcare providers, medical students, and the public. Conclusions/Impact: This is one of the few organizations with national exposure that highlights sex and gender differences in the opioid crisis and aims to increase health literacy for both the general public and health care providers. We have successfully distributed information regarding sex differences in opioid addiction during Women’s Health Week 2020 on the national AMWA website, Instagram, and Twitter. Our future plans include producing and sharing videos on YouTube about opioids, addiction, and pain management, especially in women. We hope to encourage current and future physicians to initiate discussions surrounding sex/gender-speciffc health, speciffcally in opioid addiction.https://jdc.jefferson.edu/sexandgenderhealth/1003/thumbnail.jp

Neutrino masses from new generations

We reconsider the possibility that Majorana masses for the three known neutrinos are generated radiatively by the presence of a fourth generation and one right-handed neutrino with Yukawa couplings and a Majorana mass term. We find that the observed light neutrino mass hierarchy is not compatible with low energy universality bounds in this minimal scenario, but all present data can be accommodated with five generations and two right-handed neutrinos. Within this framework, we explore the parameter space regions which are currently allowed and could lead to observable effects in neutrinoless double beta decay, $\mu - e$ conversion in nuclei and $\mu \rightarrow e \gamma$ experiments. We also discuss the detection prospects at LHC.Comment: 28 pages, 4 figures. Version to be published. Some typos corrected. Improved figures 3 and

The history and evolution of the clinical effectiveness of haemophilia type a treatment: a systematic review.

First evidence of cases of haemophilia dates from ancient Egypt, but it was when Queen Victoria from England in the 19th century transmitted this illness to her descendants, when it became known as the "royal disease". Last decades of the 20th century account for major discoveries that improved the life expectancy and quality of life of these patients. The history and evolution of haemophilia healthcare counts ups and downs. The introduction of prophylactic schemes during the 1970s have proved to be more effective that the classic on-demand replacement of clotting factors, nevertheless many patients managed with frequent plasma transfusions or derived products became infected with the Human Immunodeficiency Virus (HIV) and Hepatitis C virus during the 1980s and 1990s. Recombinant factor VIII inception has decreased the risk of blood borne infections and restored back longer life expectancies. Main concerns for haemophilia healthcare are shifting from the pure clinical aspects to the economic considerations of long-term replacement therapy. Nowadays researchers' attention has been placed on the future costs and cost-effectiveness of costly long-term treatment. Equity considerations are relevant as well, and alternative options for less affluent countries are under the scope of further research. The aim of this review was to assess the evidence of different treatment options for haemophilia type A over the past four decades, focusing on the most important technological advances that have influenced the natural course of this "royal disease"

Collective emotions online and their influence on community life

E-communities, social groups interacting online, have recently become an object of interdisciplinary research. As with face-to-face meetings, Internet exchanges may not only include factual information but also emotional information - how participants feel about the subject discussed or other group members. Emotions are known to be important in affecting interaction partners in offline communication in many ways. Could emotions in Internet exchanges affect others and systematically influence quantitative and qualitative aspects of the trajectory of e-communities? The development of automatic sentiment analysis has made large scale emotion detection and analysis possible using text messages collected from the web. It is not clear if emotions in e-communities primarily derive from individual group members' personalities or if they result from intra-group interactions, and whether they influence group activities. We show the collective character of affective phenomena on a large scale as observed in 4 million posts downloaded from Blogs, Digg and BBC forums. To test whether the emotions of a community member may influence the emotions of others, posts were grouped into clusters of messages with similar emotional valences. The frequency of long clusters was much higher than it would be if emotions occurred at random. Distributions for cluster lengths can be explained by preferential processes because conditional probabilities for consecutive messages grow as a power law with cluster length. For BBC forum threads, average discussion lengths were higher for larger values of absolute average emotional valence in the first ten comments and the average amount of emotion in messages fell during discussions. Our results prove that collective emotional states can be created and modulated via Internet communication and that emotional expressiveness is the fuel that sustains some e-communities.Comment: 23 pages including Supporting Information, accepted to PLoS ON