Dimensions, septation, and pattern of pneumatization of the sphenoidal sinus

The endoscopic endonasal transsphenoidal approach (EEA) to treat sellar, parasellar, and suprasellar tumours continues to gain increased significance. Due to the close proximity of the sphenoid sinus to the carotid artery and the optic canal, it is very important for surgeons to know the anatomical features and variations of the sphenoid sinus as relevant to EEA. A prospective study of the sphenoid sinus morphology was carried out on the cranial tomographic (CT) scan images of 60 Nigerian adult patients. The CTs were reviewed regarding the different anatomical variations of the sphenoid sinus: dimensions, septation, and pattern of pneumatisation. There were 37 males and 23 females. The patients’ ages ranged from 18 years to 85 years, with a mean of 47.2 years. There was a main single intersphenoid septum in most patients (95%). The insertion of the septum was usually to the right posteriorly (38%) and in the midline anterior (65%). Although there is usually a main septum, the septa present were multiple in 29 of the sinuses studied. There was no gender difference with respect to the attachment of the main sphenoid sinus septum. The sphenoid anterior, posterior, and transverse dimensions were not significantly dependent on age, but they were longer in males than in females. Sellar pneumatization was present in the majority of the patients (83%), with 4 patients having postsellar pneumatization (6.7%) and 3 patients having presellar pneumatization (5%).There were no cases with conchal pneumatization or lateral pneumatization of the greater wing of the sphenoid. The present study provides anatomical information about the sphenoid sinus dimensions morphology that is essential for avoiding complications in performing an endoscopic sphenoidotomy

Performance characteristics, nutrient digestibility and blood profile of rabbits fed diets containing graded levels of Moringa oleifera seed powder

A ten-week feeding trial was conducted to determine the performance, nutrient digestibility and blood profile of rabbits fed diets containing graded levels of Moringa oleifera seed powder (MSP). Twenty-four male growing rabbits of mixed breeds were randomly allotted to four dietary treatments. Each treatment group was further sub-divided into three (3) replicates of two (2) rabbits each in a completely randomized design (CRD). Four diets were formulated to include MSP at varying inclusion levels of 0, 0.5, 1 and 2% for treatments T1, T2, T3 and T4 respectively, which were pelletized. Feed and water were provided ad-libitum. Data were collected on growth performance and nutrient digestibility of rabbits fed the experimental diet while at the end of the experiment, blood samples were collected to determine the effect of different inclusion levels of MSP on haematological and serum biochemical indices of rabbits. Result revealed that the average daily feed intake (68.76-78.93g) decreased significantly (p<0.05) across the dietary treatments as the MSP inclusion levels increased but a rise was noticed at the highest inclusion level of MSP (T4). The weight gain and feed conversion ratio (FCR) were not significantly influenced (p >0.05) by the dietary treatments. No significant differences (P>0.05) among treatments were observed on all the blood profile except the lymphocyte, monocytes, total protein and globulin. Rabbits on T4 recorded the highest values in total protein (6.91 g/dl) and globulin (3.03 g/dl). Digestibility studies however showed that all the parameters were significantly affected (p<0.05) by dietary treatments in which rabbits on T2 had the highest dry matter (82.03%), crude protein (62.23%) and ash (89.48%) digestibility values. It can be concluded that Moringa oleifera seed powder (MSP) can be supplemented in growing rabbit’s diet without any deleterious effects on performance, blood profile and nutrient digestibility.Keywords: Moringa oleifera, Performance, Blood profile, Nutrient digestibility, Rabbit

Seasonal Variations in the Composition and Distribution of Planktonic Fauna in the Eastern Lagos Lagoon, Nigeria

The composition and distribution of planktonic fauna (adult form of zooplankton and planktonic juvenile forms of higher animals) within the eastern part of the Lagos Lagoon were investigated in July, 2008 and March, 2009 representing rainy and dry season respectively. Samples of water and planktonic fauna were collected from twelve stations within the eastern axis of the Lagoon and analyzed using standard methods. The study area had brackish water characteristics with fresh water condition (0\u2030 salinity across the 12 stations) in the rainy season whereas the salinity ranged from 11.4\u2030 to 30.5\u2030 in the dry season. The adult forms zooplankton recorded in the rainy season were mainly Crustaceans, Chaetognathans and Rotifers while those collected during dry season belonged to Crustacean, Cnidaria and Chordata. Crustaceans dominate both adult zooplankton and planktonic juvenile fauna in the two seasons. The rainy season adult zooplankton count (515) was lower than that of dry season (580) but the reverse was the case for the juvenile stages count (520 and 325 in rainy and dry season respectively). Higher species abundance was recorded for both adult zooplankton (20) and juvenile stages (10) in rainy than dry season when 14 and 8 were recorded for the two groups respectively. Higher values were also of community structure indices (Margalef species richness and Shannon-Wiener species diversity) were recorded in the rainy than dry season for the two groups of planktonic fauna. The findings show the influence of salinity gradients on distribution of planktonic fauna of the Lagos Lagoon

Parental Knowledge and Attitude of Adolescent Sexuality Education in Rural and Urban Communities of Ekiti State, Nigeria

Background: Parents play a key role in shaping the attitudes and behaviour of adolescents, thereby reducing risky sexual behaviour and promoting healthy sexual development. This study assessed and compared parental knowledge and attitude towards adolescent sexuality education (ASE) in rural and urban communities of Ekiti State, Nigeria.Materials and Methods: A comparative cross-sectional study of 800 parents (or guardians) of adolescents in selected rural and urban communities, recruited through a multi-stage sampling technique. An interviewer-administered semi-structured questionnaire was used to collect data. Data were analysed using SPSS version 20.Result: A significantly higher proportion of parents from the urban communities had a good knowledge of ASE (72.5% versus 66.0%, p-value 0.046). However, knowledge of safe sex and dating was low in both communities. About three-quarters of the respondents had a positive attitude towards ASE with no statistically significant difference in both rural and urban communities (p-value: 0.363).Conclusion: Parental knowledge of ASE is high in Ekiti State, and it is higher in the urban compared to the rural communities. Attitude towards ASE is high in both communities but not significantly different. However, the knowledge of the various components of ASE varies significantly amongst the communities. While it is recommended that government should create a supportive environment to assist parents in their roles as sexuality educators, parents should see sexuality education as their responsibility and also start the discussion early

The integration of artificial intelligence in medical imaging practice: Perspectives of African radiographers

Introduction The current technological developments in medical imaging are centred largely on the increasing integration of artificial intelligence (AI) into all equipment modalities. This survey assessed the perspectives of African radiographers on the integration of AI in medical imaging in order to offer unique recommendations to support the training of the radiography workforce. Methods An exploratory cross-sectional online survey of radiographers working within Africa was conducted from March to August 2020. The survey obtained data about their demographics and perspectives on AI implementation and usage. Data obtained were analysed using both descriptive and inferential statistics. Results A total of 1020 valid responses were obtained. Majority of the respondents (n = 883,86.6%) were working in general X-ray departments. Of the respondents, 84.9% (n = 866) indicated that AI technology would improve radiography practice and quality assurance for efficient diagnosis and improved clinical care. Fear of job losses following the implementation of AI was a key concern of most radiographers (n = 625,61.3%). Conclusion Generally, radiographers were delighted about the integration of AI into medical imaging, however; there were concerns about job security and lack of knowledge. There is an urgent need for stakeholders in medical imaging infrastructure development and practices in Africa to start empowering radiographers through training programmes, funding, motivational support, and create clear roadmaps to guide the adoption and integration of AI in medical imaging in Africa. Implication for practice The current study offers unique suggestions and recommendations to support the training of the African radiography workforce and others in similar resource-limited settings to provide quality care using AI-integrated imaging modalities

Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021

Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5–65·1] decline), and increased during the COVID-19 pandemic period (2020–21; 5·1% [0·9–9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98–5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50–6·01) in 2019. An estimated 131 million (126–137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7–17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). Global life expectancy at birth declined by 1·6 years (1·0–2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67–8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4–52·7]) and south Asia (26·3% [9·0–44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic. Funding: Bill & Melinda Gates Foundation

A rare case of pyometrocolpos with obstructive uropathy: sequelae of distal vaginal atresia

Hydrometrocolpos is a rare abnormality in female newborns. It follows congenital vaginal obstruction which may present as a midline abdominal mass causing either urinary tract or gastrointestinal tract obstruction without a coexisting bowel anomaly. Our experience was that of an infant with obstructive uropathy from an infected hydrometrocolpos.Keywords: Hydrometrocolpos, Vaginal obstruction, Obstructive uropath

Hydrostatic reduction of intussusception with normal saline using the gravity aided method in a Nigerian teaching hospital

Background: The non-operative treatment of intussusception has evolved over the years. One of such treatment modalities is ultrasound guided hydrostatic reduction using barium, saline and other water soluble agents. Despite the benefits of this method, surgery remains the mainstay of treatment in our hospital as well as in many other Nigerian hospitals.Aim: To evaluate the success rate of ultrasound guided hydrostatic reduction of intussusception using the gravity aided saline reduction method.Method: This is a prospective study of hydrostatic reduction of intussusception using the gravity aided saline reduction method. Patients were seen between January and December 2015.Results: Thirty five cases who were confirmed to have intussusception by ultrasonography were seen but only 12 were suitable for the procedure. Seven patients (58.3%) had successful hydrostatic gravity aided saline reductions while five (41.7%) had failed reductions. One patient had a recurrence. Bowel perforation complicated the procedure in one patient, who required a laparotomy for further management.Conclusion: Ultrasound guided hydrostatic reduction with normal saline by gravity method is a reliable and safe method of reducing intussusceptions in carefully selected cases. Thus, it should be recommended as the primary mode of treatment provided there are no features of peritonitis.Keywords: Intussusception; ultrasound guided gravity and saline reductio

Seasonal Variations in the Composition and Distribution of Planktonic Fauna in the Eastern Lagos Lagoon, Nigeria

The composition and distribution of planktonic fauna (adult form of zooplankton and planktonic juvenile forms of higher animals) within the eastern part of the Lagos Lagoon were investigated in July, 2008 and March, 2009 representing rainy and dry season respectively. Samples of water and planktonic fauna were collected from twelve stations within the eastern axis of the Lagoon and analyzed using standard methods. The study area had brackish water characteristics with fresh water condition (0‰ salinity across the 12 stations) in the rainy season whereas the salinity ranged from 11.4‰ to 30.5‰ in the dry season. The adult forms zooplankton recorded in the rainy season were mainly Crustaceans, Chaetognathans and Rotifers while those collected during dry season belonged to Crustacean, Cnidaria and Chordata. Crustaceans dominate both adult zooplankton and planktonic juvenile fauna in the two seasons. The rainy season adult zooplankton count (515) was lower than that of dry season (580) but the reverse was the case for the juvenile stages count (520 and 325 in rainy and dry season respectively). Higher species abundance was recorded for both adult zooplankton (20) and juvenile stages (10) in rainy than dry season when 14 and 8 were recorded for the two groups respectively. Higher values were also of community structure indices (Margalef species richness and Shannon-Wiener species diversity) were recorded in the rainy than dry season for the two groups of planktonic fauna. The findings show the influence of salinity gradients on distribution of planktonic fauna of the Lagos Lagoon

Adoption of homestead grain storage technology in the south-west agricultural zone of Nigeria

The major types of grains and pulses that are stored in Ekiti, Ondo, Edo, Delta, Oyo, Ogun, Osun and Lagos states of Nigeria at homestead level are maize, guinea corn, rice, cowpea, Soya bean and groundnut. Bags, hermetic containers and room spaces are used for storage. The adoption of improved storage technology in hermetic containers, cold treatment, polythene lined bags and application of recommended chemicals was relatively low (45%) due to lack of/and inadequate knowledge of usage of these technologies, non-availability and high costs of storage inputs especially the recommended chemicals, and lack of awareness of the technologies. The training and visits (T&V) System of the Agricultural Development Project (ADP) was found to be the most prevalent source of information to the respondents, followed by the radio. Increased use of interpersonal communication as well as prompt and adequate intervention by government in the provision of credit facilities and subsidy on storage inputs among others will enhance the rate of adoption.. [JEXT Vol.1(1) 2000: 82-88