979 research outputs found

    Men, masculinities and emotion: understanding the connections between men’s perpetration of intimate partner violence, alcohol use and sexual behaviour in Dharavi, Mumbai

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    Background: An increasing men's studies movement attempts to understand how different masculine norms affect men's health and behaviour and how behaviours such as alcohol use and violence act as ways of coping both with the pressure to fulfil masculine norms and with emotional distress. However, the vast majority of this work has been in western contexts. This study sought to extend this fairly western-centric work by examining the relationships between gender norms, emotional distress and men's alcohol use, perpetration of intimate partner violence (IPV) and sexual behaviour in a low-income area of Mumbai, India. Methods: Secondary quantitative data (n=2,381) from a survey of men in three low-income districts in Mumbai were analysed in order to identify psychosocial factors associated with men's perpetration of IPV, alcohol use and extramarital sex. A period of fieldwork was undertaken in Dharavi, Mumbai in 2009-10 which included in-depth interviews with 29 married men, aged 21-52. Results Quantitative analyses found evidence for associations between men's ability to fulfil masculine norms and perpetration of IPV as well as psychological distress. Qualitative interviews highlighted the range of norms men were exposed to, defended and contested. Many men struggled to fulfil dominant notions of masculinity. In addition, many men had poor emotional and social support, frequently dealing with distress on their own. Men reported using behaviour such as alcohol use, violence and extramarital sex as ways of dealing with difficult emotions, social isolation, as well as a range of difficulties in their marital relationships. Conclusion: Norms around masculinity and the effects these have upon men emotionally are important in understanding men's involvement in these behaviours in this context. Understanding men as gendered as well as emotional beings is important in engaging with a wide variety of men in order to bring about lasting social as well as behavioural change

    Intranasal Resveratrol Nanoparticles Enhance Neuroprotection in a Model of Multiple Sclerosis.

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    Resveratrol is a natural polyphenol which has a very low bioavailability but whose antioxidant, anti-inflammatory and anti-apoptotic properties may have therapeutic potential for the treatment of neurodegenerative diseases such as multiple sclerosis (MS). Previously, we reported the oral administration of resveratrol nanoparticles (RNs) elicited a neuroprotective effect in an experimental autoimmune encephalomyelitis (EAE) mouse model of MS, at significantly lower doses than unconjugated resveratrol (RSV) due to enhanced bioavailability. Furthermore, we demonstrated that the intranasal administration of a cell-derived secretome-based therapy at low concentrations leads to the selective neuroprotection of the optic nerve in EAE mice. The current study sought to assess the potential selective efficacy of lower concentrations of intranasal RNs for attenuating optic nerve damage in EAE mice. EAE mice received either a daily intranasal vehicle, RNs or unconjugated resveratrol (RSV) for a period of thirty days beginning on the day of EAE induction. Mice were assessed daily for limb paralysis and weekly for visual function using the optokinetic response (OKR) by observers masked to treatment regimes. After sacrifice at day 30, spinal cords and optic nerves were stained to assess inflammation and demyelination, and retinas were immunostained to quantify retinal ganglion cell (RGC) survival. Intranasal RNs significantly increased RGC survival at half the dose previously shown to be required when given orally, reducing the risk of systemic side effects associated with prolonged use. Both intranasal RSV and RN therapies enhanced RGC survival trends, however, only the effects of intranasal RNs were significant. RGC loss was prevented even in the presence of inflammatory and demyelinating changes induced by EAE in optic nerves. The intranasal administration of RNs is able to reduce RGC loss independent of the inflammatory and demyelinating effects on the optic nerve and the spinal cord. The concentration of RNs needed to achieve neuroprotection is lower than previously demonstrated with oral administration, suggesting intranasal drug delivery combined with nanoparticle conjugation warrants further exploration as a potential neuroprotective strategy for the treatment of optic neuritis, alone as well as in combination with glucocorticoids

    Asymptomatic Thoracic Kidney

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/66641/2/10.1177_000992286900800510.pd

    Upper estimate of martingale dimension for self-similar fractals

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    We study upper estimates of the martingale dimension dmd_m of diffusion processes associated with strong local Dirichlet forms. By applying a general strategy to self-similar Dirichlet forms on self-similar fractals, we prove that dm=1d_m=1 for natural diffusions on post-critically finite self-similar sets and that dmd_m is dominated by the spectral dimension for the Brownian motion on Sierpinski carpets.Comment: 49 pages, 7 figures; minor revision with adding a referenc

    Scattering of light and atoms in a Fermi-Dirac gas with BCS pairing

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    We theoretically study the optical properties of a Fermi-Dirac gas in the presence of a superfluid state. We calculate the leading quantum-statistical corrections to the standard column density result of the electric susceptibility. We also consider the Bragg diffraction of atoms by means of light-stimulated transitions of photons between two intersecting laser beams. Bardeen-Cooper-Schrieffer pairing between atoms in different internal levels magnifies incoherent scattering processes. The absorption linewidth of a Fermi-Dirac gas is broadened and shifted. Bardeen-Cooper-Schrieffer pairing introduces a collisional local-field shift that may dramatically dominate the Lorentz-Lorenz shift. For the case of the Bragg spectroscopy the static structure function may be significantly increased due to superfluidity in the nearforward scattering.Comment: 13 pages, 6 figures; to appear in PR

    Solar Neutrinos and the Principle of Equivalence

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    We study the proposed solution of the solar neutrino problem which requires a flavor nondiagonal coupling of neutrinos to gravity. We adopt a phenomenological point of view and investigate the consequences of the hypothesis that the neutrino weak interaction eigenstates are linear combinations of the gravitational eigenstates which have slightly different couplings to gravity, f1Gf_1G and f2Gf_2G, f1f2<<1|f_1-f_2| << 1, corresponding to a difference in red-shift between electron and muon neutrinos, Δz/(1+z)f1f2\Delta z/(1+z) \sim |f_1 - f_2|. We perform a χ2\chi^2 analysis of the latest available solar neutrino data and obtain the allowed regions in the space of the relevant parameters. The existing data rule out most of the parameter space which can be probed in solar neutrino experiments, allowing only f1f23×1014|f_1 - f_2| \sim 3 \times 10^{-14} for small values of the mixing angle (2×103sin2(2θG)1022 \times 10^{-3} \le \sin^2(2\theta_G) \le 10^{-2}) and 1016<f1f2<101510^{-16} \stackrel{<}{\sim} |f_1 - f_2| \stackrel{<}{\sim}10^{-15} for large mixing (0.6sin2(2θG)0.90.6 \le \sin^2(2\theta_G) \le 0.9). Measurements of the 8B^8{\rm B}-neutrino energy spectrum in the SNO and Super-Kamiokande experiments will provide stronger constraints independent of all considerations related to solar models. We show that these measurements will be able to exclude part of the allowed region as well as to distinguish between conventional oscillations and oscillations due to the violation of the equivalence principle.Comment: 20 pages + 4 figures, IASSNS-AST 94/5

    Western oceanus procellarum as seen by c1xs on chandrayaan-1

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    We present the analysis of an X-ray fluorescence (XRF) observation of the western part of Oceanus Procellarum on the Moon’s nearside made by the Chandrayaan-1 X-ray Spectrometer on 10th February 2009. Through forward modelling of the X-ray spectra, we provide estimates of the MgO/SiO2 and Al2O3/SiO2 ratios for seven regions along the flare’s ground track. These results are combined with FeO and TiO2 contents derived from Clementine multispectral reflectance data in order to investigate the compositional diversity of this region of the Moon. The ground track observed consists mainly of low-Ti basaltic units, and the XRF data are largely consistent with this expectation. However, we obtain higher Al2O3/SiO2 ratios for these units than for most basalts in the Apollo sample collection. The widest compositional variation between the different lava flows is in wt% FeO content. A footprint that occurs in a predominantly highland region, immediately to the north of Oceanus Procellarum, has a composition that is consistent with mixing between low-Ti mare basaltic and more feldspathic regoliths. In contrast to some previous studies, we find no evidence for systematic differences in surface composition, as determined through X-ray and gamma-ray spectroscopy techniques

    Generation and evolution of vortex-antivortex pairs in Bose-Einstein condensates

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    We propose a method for generating and controlling a spatially separated vortex--antivortex pair in a Bose-Einstein condensate trapped in a toroidal potential. Our simulations of the time dependent Gross-Pitaevskii equation show that in toroidal condensates vortex dynamics are different from the dynamics in the homogeneous case. Our numerical results agree well with analytical calculations using the image method. Our proposal offers an effective example of coherent generation and control of vortex dynamics in atomic condensates.Comment: 4 pages, 2 figure
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