Mononitration of durene

Reaction conditions under which the nitration of durene give predominantly, and in high yield, mononitrodurene (I), rather than dinitrodurene were found. The nitrating agent was No2+RF6-. Nitration with nitrosulfuric acid also gave mononitrodurene; however, byproducts such as 2.3.5.6-Me4C6HCH2C6H2Me3-2,4,5, were also formed. The NO2 PF6- gave an intermediate additional compound with durene. The reaction carried out with 3.6-dideuterodurene in D2O shows no isotope effect

Collodial particles at a range of fluid-fluid particles

The study of solid particles residing at fluid-fluid interfaces has become an established area in surface and colloid science recently experiencing a renaissance since around 2000. Particles at interfaces arise in many industrial products and processes like anti-foam formulations, crude oil emulsions, aerated foodstuffs and flotation. Although they act in many ways like traditional surfactant molecules, they offer distinct advantages also and the area is now multi-disciplinary involving research in the fundamental science and potential applications. In this Feature Article, a flavour of some of this interest is given based on recent work from our own group and includes the behaviour of particles at oil-water, air-water, oil-oil, air-oil and water-water interfaces. The materials capable of being prepared by assembling various kinds of particles at fluid interfaces include particle-stabilised emulsions, particle-stabilised aqueous and oil foams, dry liquids, liquid marbles and powdered emulsions

Theoretical aspects of the study of top quark properties

We review some recent theoretical progresses towards the determination of the top-quark couplings beyond the standard model. We briefly introduce the global effective field theory approach to the top-quark production and decay processes, and discuss the most useful observables to constrain the deviations. Recent improvements with a focus on QCD corrections and corresponding tools are also discussed.Comment: 8 pages, 6 figures. Based on plenary talk given at LHCP2017, Shanghai, 15-20 May 201

Dental Workforce Report of Indiana University School of Dentistry Graduates and Other Practicing Dentists in Indiana

All dentists who renewed their Indiana licenses on - line in 2010 or 2012 were asked to complete a voluntary survey instrument that ha d a 95.4% response rate 1 in 2010 and 80.7% response rate 2 in 2012. The purpose of this study was to describe the dental workforce in Indiana with a focus on comparing graduates from the Indiana University School of Dentistry (IUSD) to all other practicing ( n on - IUSD ) dentists in Indiana. Of primary interest is how well the graduates of IUSD are meeting the oral health needs of the population of the state, particularly in the rural and underserved areas. Using data from the Office of Alumni Relations at IUPUI, license numbers of IUSD alumni were matched to the license numbers of individuals in the 2010 or 2012 Indiana Dentist Licensure Survey datasets. Individuals whose license numbers matched with the alumni list were identified as “IUSD” graduates and those that did not match were identified as “non - IUSD” graduates. This report compares responses between 2,203 IUSD and 835 n on - IUSD graduates who renewed their licenses and completed the Indiana Dentist Licensure Surveys in 2010 or 2012, respectively. Lastly, most of the differences between groups were found to be statistically significant due to the large sample size of IUSD graduates compared to non - IUSD graduates. Thus, for the purposes of this report if the differences between groups were noted to be at least 10 percent they were considered remarkable and reported as such

User Experience Design for E-Voting: How mental models align with security mechanisms

This paper presents a mobile application for vote-casting and vote-verification based on the Selene e-voting protocol and explains how it was developed and implemented using the User Experience Design process. The resulting interface was tested with 38 participants, and user experience data was collected via questionnaires and semi-structured interviews on user experience and perceived security. Results concerning the impact of displaying security mechanisms on UX were presented in a complementary paper. Here we expand on this analysis by studying the mental models revealed during the interviews and compare them with theoretical security notions. Finally, we propose a list of improvements for designs of future voting protocols.Comment: E-Vote-ID 2019 TalTech Proceeding

Glial βii spectrin contributes to paranode formation and maintenance

Action potential conduction along myelinated axons depends on high densities of voltage-gated Na channels at the nodes of Ranvier. Flanking each node, paranodal junctions (paranodes) are formed between axons and Schwann cells in the peripheral nervous system (PNS) or oligodendrocytes intheCNS. Paranodal junctions contribute to both no deassembly and maintenance. Despitetheir importance, the molecular mechanisms responsible for paranode assembly and maintenance remain poorly understood. βII spectrin is expressed in diverse cells and is an essential part of the submembranous cytoskeleton. Here, we show that Schwann cell βII spectrin is highly enriched at paranodes. To elucidate the roles of glial βII spectrin, we generated mutant mice lacking βII spectrin in myelinating glial cells by crossing mice with a floxed allele of Sptbn1 with Cnp-Cre mice, and analyzed both male and female mice. Juvenile (4 weeks) and middle-aged (60 weeks) mutant mice showed reduced grip strength and sciatic nerve conduction slowing, whereas no phenotype was observed between 8 and 24 weeks of age. Consistent with these findings, immunofluorescence microscopy revealed disorganized paranodes in the PNS and CNS of both postnatal day 13 and middle-aged mutant mice, but not in young adult mutant mice. Electron microscopy confirmed partial loss of transverse bands at the paranodal axoglial junction in the middle-aged mutant mice in both the PNS and CNS. These findings demonstrate that a spectrin-based cytoskeleton in myelinating glia contributes to formation and maintenance of paranodal junctions.Fil: Susuki, Keiichiro. Baylor College of Medicine; Estados UnidosFil: Zollinger, Daniel R.. Baylor College of Medicine; Estados UnidosFil: Chang, Kae Jiun. Baylor College of Medicine; Estados UnidosFil: Zhang, Chuansheng. Baylor College of Medicine; Estados UnidosFil: Huang, Claire Yu Mei. Baylor College of Medicine; Estados UnidosFil: Tsai, Chang Ru. Baylor College of Medicine; Estados UnidosFil: Galiano, Mauricio Raul. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Centro de Investigaciones en Química Biológica de Córdoba. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas. Centro de Investigaciones en Química Biológica de Córdoba; Argentina. Baylor College of Medicine; Estados UnidosFil: Liu, Yanhong. Baylor College of Medicine; Estados UnidosFil: Benusa, Savannah D.. Virginia Commonwealth University; Estados UnidosFil: Yermakov, Leonid M.. Wright State University; Estados UnidosFil: Griggs, Ryan B.. Wright State University; Estados UnidosFil: Dupree, Jeffrey L.. Virginia Commonwealth University; Estados UnidosFil: Rasband, Matthew N.. Baylor College of Medicine; Estados Unido

Effect of Ce and Sb on Primary Graphite Growth in Cast Irons

It is well-known that if certain trace elements are present in cast iron melts the morphology of the graphite precipitates can be altered. In order to understand the effect of doping elements on primary growth of graphite, pure Fe–Sb alloys were prepared by induction melting. They were then placed in graphite crucibles and heated to a temperature above the Fe–C eutectic so that the charge became saturated in carbon and melted. To obtain Fe–Ce alloys, metallic Ce was added at the bottom of a graphite crucible and covered with iron, and then heated as for the Fe–Sb charge. In both cases, the melt was then cooled and held slightly above the eutectic temperature so that primary graphite crystals, which had nucleated on the crucible walls and then detached from it, could grow freely in the melt. The influence of the added elements on graphite growth was revealed by the change in the shape and distribution of the crystals compared to those obtained in similar experiments carried out with pure Fe. The experiments were made in air and vacuum so as to point out possible interactions between the elements present in the melt and oxygen

Issue Brief: Indiana’s Health Professions Workforce Shortages and Mal-distribution

Workforce shortages have been documented across a broad spectrum of health profession disciplines in Indiana. Currently, federal, state and local programs exist to recruit and retain health professionals in our state; however, these programs have had minimal impact on the underlying factors that contribute to the problem. Additional steps must be taken to expand the supply of health professionals to adequately meet the growing need for health care services among Indiana residents. While many health professional shortages exist, this brief will focus on the primary care physicians and nurses needed to provide medical homes for residents of our state

Etablissement de la texture au cours du soudage TIG d’alliages austénitiques : soudures réelles et numériques

The structure prediction of metallic alloys during a welding or additive manufacturing process is the key point for the joining’s properties. In addition to the welding parameters (or additive manufacturing), the base metal microstructure, chemical homogeneity and crystallographic structure are numerous factors playing an important role on the final microstructure and texture development. Few studies are available in this way. This work purposes a focus on the microstructure establishment during the welded zone solidification during Gas Tungsten Arc Welding. The materials investigated are nickel – chromium – iron austenitic alloys. The grain selection is tracked in a real weld and a texturation criteria is proposed. The following data’s are compared to the properties of the numerical weld experience. The conclusion suggests that is necessary to improve the knowledges in the grain selection mechanism in order to produce numerical welding microstructure in good accordance with real microstructure welding.La prédiction de la structure des alliages métalliques durant une étape de soudage ou de fabrication additive est un point clef du développement de ces procédés et des propriétés des assemblages. En plus des paramètres de soudage (ou de fabrication additive), la microstructure du métal de base, son homogénéité chimique et sa nature cristallographique sont autant de facteur jouant un rôle sur l’établissement final des microstructures et des textures pour lesquels peu d’études détaillées sont disponibles. Une description précise de l’établissement des microstructures de solidification lors du soudage TIG d’alliage austénitique nickel-chrome-fer est réalisée dans ce travail. La sélection des grains dans la soudure est suivie dans une soudure réelle. Un critère de texturation est proposé et les données sont comparées aux textures simulées d’où il ressort l’importance d’augmenter la connaissance des mécanismes de sélection de grains pour espérer modéliser encore plus fidèlement les propriétés microstructurales et de texture générées par le soudage