6,067 research outputs found

    Expand your professional horizons: Rethink your limits

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    Staff working in higher education have the opportunity to improve their skills and broaden their horizons by taking part in Erasmus+. Having made two trips abroad, we share our experience and viewpoint on the benefits of Erasmus+ activities for staff, their school/services and students

    Pylos and Sphacteria

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    High resolution spectroscopy of Pluto's atmosphere: detection of the 2.3 Ό\mum CH4_4 bands and evidence for carbon monoxide

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    The goal is to determine the composition of Pluto's atmosphere and to constrain the nature of surface-atmosphere interactions. We perform high--resolution spectroscopic observations in the 2.33--2.36 ÎŒ\mum range, using CRIRES at the VLT. We obtain (i) the first detection of gaseous methane in this spectral range, through lines of the Îœ3\nu_3 + Îœ4\nu_4 and Îœ1\nu_1 + Îœ4\nu_4 bands (ii) strong evidence (6-σ\sigma confidence) for gaseous CO in Pluto. For an isothermal atmosphere at 90 K, the CH4_4 and CO column densities are 0.75 and 0.07 cm-am, within factors of 2 and 3, respectively. Using a physically--based thermal structure model of Pluto's atmosphere also satisfying constraints from stellar occultations, we infer CH4_4 and CO mixing ratios qCH4_{CH_4}= 0.6−0.3+0.6^{+0.6}_{-0.3}% (consistent with results from the 1.66 ÎŒ\mum range) and qCO_{CO} = 0.5−0.25+1^{+1}_{-0.25}×10−3\times10^{-3}. The CO atmospheric abundance is consistent with its surface abundance. As for Triton, it is probably controlled by a thin, CO-rich, detailed balancing layer resulting from seasonal transport and/or atmospheric escape.Comment: Astronomy and Astrophysics Letters, in pres

    Fertility History and Biomarkers Using Prospective Data: Evidence From the 1958 National Child Development Study

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    Research on the later-life health implications of fertility history has predominantly considered associations with mortality or self-reported indicators of health. Most of this previous research has either not been able to account for selection factors related to both early-life and later-life health or has had to rely on retrospectively reported accounts of childhood circumstances. Using the 1958 National Child Development Study, and in particular the biomedical survey conducted in 2002–2003, we investigate associations between fertility histories (number of children and age at first and at last birth) and biomarkers for cardiometabolic risk and respiratory function in midlife among both men and women. Results from models that adjusted for a very wide range of childhood factors, including early-life socioeconomic position, cognitive ability, and mental health, showed weak associations between parity and biomarkers. However, we found an inverse association between age at first birth and biomarkers indicative of worse cardiometabolic health, with poorer outcomes for those with very young ages at entry to parenthood and increasingly better outcomes for those becoming parents at older ages. A very young age at last birth was also associated with less favorable biomarker levels, especially among women. Results highlight the value of prospectively collected data and the availability of biomarkers in studies of life course determinants of health in midlife and later

    Life-course partnership history and midlife health behaviours in a population-based birth cohort

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    The research leading to these results has received funding from the European Research Council under the European Union’s Seventh Framework Programme (FP7/2007-2013)/ ERC grant agreement n° 324055.Background:  Marital and partnership history is strongly associated with health in midlife and later life. However, the role of health behaviours as an explanatory mechanism remains unclear. The aim of this study was to investigate prospective associations between life-course partnership trajectories (taking into account timing, non-marital cohabitation, remarriage and marital transitions) and health behaviours measured in midlife. Methods:  We analysed data from the British National Child Development Study, a prospective cohort study that includes all people born in 1 week of March 1958 (N=10 226). This study included men and women with prospective data on partnership history from age 23 to 42–44 and health behaviours collected at ages 42–46 (2000–2004). Latent class analysis was used to derive longitudinal trajectories of partnership history. We used multivariable regression models to estimate the association between midlife health behaviours and partnership trajectory, adjusting for various early and young adult characteristics. Results:  After adjustment for a range of potential selection factors in childhood and early adulthood, we found that problem drinking, heavy drinking and smoking were more common in men and women who experienced divorce or who had never married or cohabited. Women who married later had a lower prevalence of smoking and were less likely to be overweight than those who married earlier. Overall marriage was associated with a higher body mass index. Individuals who never married or cohabited spent less time exercising. Conclusions:  Some aspects of partnership history such as remaining unpartnered and experiencing divorce are associated with more smoking and drinking in midlife, whereas marriage is associated with midlife weight gain. Despite these offsetting influences, differences in health behaviours probably account for much of the association between partnership trajectories and health found in previous studies.Publisher PDFPeer reviewe

    Ancient Map of Asia Minor

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    Responses to selection for lean growth in sheep

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    This paper reports the selection responses achieved, and related results, following 9 years of index selection for lean growth in Suffolk sheep. The breeding goal of the index used comprised carcass lean weight and carcass fat weight at a constant age, with relative economic values of + 3 and –1 per kg. The selection criteria were live weight (LWT), ultrasonic fat depth (UFD) and ultrasonic muscle depth (UMD) adjusted to a constant age of 150 days. By year 9, responses in LWT, UFD and UMD in both sexes, as judged by the divergence between selection and control line performance, amounted to 4·88 kg, –1·1 mm and 2·8 mm respectively; these responses are between 7 and 15% of the overall means of the traits concerned. Although selection was originally on index scores based on phenotypic records, the retrospective analyses reported here used the mixed model applications of residual maximum likelihood to estimate parameters and best linear unbiased prediction to predict breeding values. The statistical model comprised fixed effects plus random effects accounting for direct additive, maternal additive and temporary environmental variation. Estimated genetic trends obtained by regressing estimated breeding values on year of birth were similar to annual responses estimated by comparing selection and control line means. Estimates of direct heritabilities were 0·054, 0·177, 0·286, 0·561 and 0·410 for birth weight (BWT), weaning weight (WWT), LWT, UFD and UMD respectively. Corresponding estimates of maternal heritabilities were 0·287, 0·205, 0·160, 0·083 and 0·164. Phenotypic correlations between all pairs of traits were positive and usually moderately high. There were low negative direct additive correlations between BWT and WWT, and between BWT and LWT, but higher positive maternal additive correlations between all other pairs of weight traits
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