Copernicus observations of C I and CO in diffuse interstellar clouds

Copernicus was used to observe absorption lines of C I in its ground state and excited fine structure levels and CO toward 29 stars. We use the C I data to infer densities and pressures within the observed clouds, and because our results are of higher precision than previous work, much more precise estimates of the physical conditions in clouds are obtained. In agreement with previous work, the interstellar thermal pressure appears to be variable, with most clouds having values of p/k between 1000/cu cm K and 10,000/cu cm K, but there are some clouds with p/k as high as 100,000/cu cm K. Our results are consistent with the view that the interstellar thermal pressure is so variable that the gas undergoes continuous dynamic evolution. Our observations provide useful constraints on the physical processes on the surfaces of grains. In particular, we find that grains are efficient catalysts of interstellar H2 in the sense that at least half of the hydrogen atoms that strike grains come off as part of H2. Results place strong constraints on models for the formation and destruction of interstellar CO. In many clouds, an order of magnitude less CO than predicted in some models was found

On Iron Enrichment, Star Formation, and Type Ia Supernovae in Galaxy Clusters

The nature of star formation and Type Ia supernovae (SNIa) in galaxies in the field and in rich galaxy clusters are contrasted by juxtaposing the build-up of heavy metals in the universe inferred from observed star formation and supernovae rate histories with data on the evolution of Fe abundances in the intracluster medium (ICM). Models for the chemical evolution of Fe in these environments are constructed, subject to observational constraints, for this purpose. While models with a mean delay for SNIa of 3 Gyr and standard initial mass function (IMF) are consistent with observations in the field, cluster Fe enrichment immediately tracks a rapid, top-heavy phase of star formation -- although transport of Fe into the ICM may be more prolonged and star formation likely continues to redshifts <1. The source of this prompt enrichment is Type II supernovae (SNII) yielding at least 0.1 solar masses per explosion (if the SNIa rate normalization is scaled down from its value in the field according to the relative number of candidate progenitor stars in the 3-8 solar mass range) and/or SNIa explosions with short delay times associated with the rapid star formation mode. Star formation is >3 times more efficient in rich clusters than in the field, mitigating the overcooling problem in numerical cluster simulations. Both the fraction of baryons cycled through stars, and the fraction of the total present-day stellar mass in the form of stellar remnants, are substantially greater in clusters than in the field.Comment: 51 pages including 26 figures and 2 tables, accepted for publication in ApJ 5/4/0

Failure to Recover from Proactive Semantic Interference Differentiates Amnestic Mild Cognitive Impairment and PreMCI from Normal Aging after Adjusting for Initial Learning Ability

Background: There is increasing evidence that the failure to recover from proactive semantic interference (frPSI) may be an early cognitive marker of preclinical Alzheimer’s disease (AD). However, it is unclear whether frPSI effects reflect deficiencies in an individual’s initial learning capacity versus the actual inability to learn new semantically related targets. Objective: The current study was designed to adjust for learning capacity and then to examine the extent to which frPSI, proactive semantic interference (PSI) and retroactive semantic interference (RSI) effects could differentiate between older adults who were cognitively normal (CN), and those diagnosed with either Pre-Mild Cognitive Impairment (PreMCI) or amnestic MCI (aMCI). Methods: We employed the LASSI-L cognitive stress test to examine frPSI, PSI and RSI effects while simultaneously controlling for the participant’s initial learning capacity among 50 CN, 35 aMCI, and 16 PreMCI participants who received an extensive diagnostic work-up. Results: aMCI and PreMCI participants showed greater frPSI deficits (50% and 43.8% respectively) compared to only 14% of CNparticipants. PSI effects were observed for aMCI but not PreMCI participants relative to their CN counterparts. RSI failed to differentiate between any of the study groups. Conclusion: By using participants as their own controls and adjusting for overall learning and memory, it is clear that frPSI deficits occur with much greater frequency in individuals at higher risk for Alzheimer’s disease (AD), and likely reflect a failure of brain compensatory mechanisms.Fil: Curiel, Rosie E.. University of Miami; Estados UnidosFil: Crocco, Elizabeth A.. University of Miami; Estados UnidosFil: Raffo, Arlene. University of Miami; Estados UnidosFil: Guinjoan, Salvador Martín. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia; ArgentinaFil: Nemeroff, Charles B.. University of Miami; Estados UnidosFil: Penate, Ailyn. Mount Sinai Medical Center; Estados Unidos. University of Miami; Estados UnidosFil: Piña, Daema. University of Miami; Estados UnidosFil: Loewenstein, David A.. Mount Sinai Medical Center; Estados Unidos. University of Miami; Estados Unido

Empathy Gaps Between Helpers and Help-Seekers: Implications for Cooperation

Help-seekers and potential helpers often experience an “empathy gap” – an inability to understand each other’s unique perspectives. Both parties are concerned about their reputation, self-esteem, and relationships, but these concerns differ in ways that lead to misinterpretation of the other party’s actions, and, in turn, missed opportunities for cooperation. In this article, we review research that describes the role-specific concerns of helpers and help-seekers. We then review studies of emotional perspective-taking, which can help explain why help-seekers and helpers often experience empathy gaps. We go on to discuss recent work that illustrates the consequences of empathy gaps between helpers and help-seekers—social prediction errors that prevent helping and misguided intentions that can lead to unhelpful help. Finally, we discuss some promising directions for future research

Prevalence and Properties of Dark Matter in Elliptical Galaxies

Given the recently deduced relationship between X-ray temperatures and stellar velocity dispersions (the "T-sigma relation") in an optically complete sample of elliptical galaxies (Davis & White 1996), we demonstrate that L>L_* ellipticals contain substantial amounts of dark matter in general. We present constraints on the dark matter scale length and on the dark-to-luminous mass ratio within the optical half-light radius and within the entire galaxy. For example, we find that minimum values of dark matter core radii scale as r_dm > 4(L_V/3L_*)^{3/4}h^{-1}_80 kpc and that the minimum dark matter mass fraction is >~20% within one optical effective radius r_e and is >~39-85% within 6r_e, depending on the stellar density profile and observed value of beta_spec. We also confirm the prediction of Davis & White (1996) that the dark matter is characterized by velocity dispersions that are greater than those of the luminous stars: sigma_dm^2 ~ 1.4-2 sigma_*^2. The T-sigma relation implies a nearly constant mass-to-light ratio within six half-light radii: M/L_V ~ 25h_80 M_sun/L_V_sun. This conflicts with the simplest extension of CDM theories of large scale structure formation to galactic scales; we consider a couple of modifications which can better account for the observed T-sigma relation.Comment: 27 pages AASTeX; 15 PostScript figures; to appear in Ap

APOE epsilon 4 carriers may undergo synaptic damage conferring risk of Alzheimer's disease

INTRODUCTION: Pathogenesis of Alzheimer's disease (AD) in apolipoprotein E ε4 (APOE ε4) carriers remains unclear. We hypothesize that APOE isoforms have differential effects on synaptic function. METHODS: We compared levels of CSF neurogranin (Ng) between APOE ε4 carriers and noncarriers in 399 subjects with normal cognition, mild cognitive impairment (MCI), and AD. We examined associations between Ng levels and age, education, gender, CSF-Aβ42, and tau protein. RESULTS: Neurogranin levels were significantly higher in APOE ε4 carriers compared to APOE ε4 noncarriers with MCI. Levels of Ng between the APOE ε4 carriers and APOE ε4 noncarriers with AD did not differ. Ng levels were correlated with MMSE and levels of tau and Aβ42. DISCUSSION: Significantly higher CSF Ng levels in APOE ε4 carriers with MCI may reflect synaptic injury underlying early cognitive impairment. Neurogranin may be an early biomarker of AD and important for disease diagnosis and timing of intervention in APOE ε4 carriers

Single molecule experiments in biophysics: exploring the thermal behavior of nonequilibrium small systems

Biomolecules carry out very specialized tasks inside the cell where energies involved are few tens of k_BT, small enough for thermal fluctuations to be relevant in many biomolecular processes. In this paper I discuss a few concepts and present some experimental results that show how the study of fluctuation theorems applied to biomolecules contributes to our understanding of the nonequilibrium thermal behavior of small systems.Comment: Proceedings of the 22nd Statphys Conference 2004 (Bangalore,India). Invited contributio

Intermediate Element Abundances in Galaxy Clusters

We present the average abundances of the intermediate elements obtained by performing a stacked analysis of all the galaxy clusters in the archive of the X-ray telescope ASCA. We determine the abundances of Fe, Si, S, and Ni as a function of cluster temperature (mass) from 1--10 keV, and place strong upper limits on the abundances of Ca and Ar. In general, Si and Ni are overabundant with respect to Fe, while Ar and Ca are very underabundant. The discrepancy between the abundances of Si, S, Ar, and Ca indicate that the alpha-elements do not behave homogeneously as a single group. We show that the abundances of the most well-determined elements Fe, Si, and S in conjunction with recent theoretical supernovae yields do not give a consistent solution for the fraction of material produced by Type Ia and Type II supernovae at any temperature or mass. The general trend is for higher temperature clusters to have more of their metals produced in Type II supernovae than in Type Ias. The inconsistency of our results with abundances in the Milky Way indicate that spiral galaxies are not the dominant metal contributors to the intracluster medium (ICM). The pattern of elemental abundances requires an additional source of metals beyond standard SNIa and SNII enrichment. The properties of this new source are well matched to those of Type II supernovae with very massive, metal-poor progenitor stars. These results are consistent with a significant fraction of the ICM metals produced by an early generation of population III stars.Comment: 18 pages, 11 figures, 7 tables. Submitted to Ap

The Iowa Homemaker vol.9, no.7

Adrift in Chicago by Two Home Economicers Who Are, page 1 Aluminum Cooking Utensils by P. Mabel Nelson, Ph. D., page 3 Health and Hygiene, page 3 Art in Shoes by Gertrude Vincent, page 4 Why Go to College? by Rosemary Keoberie, page 4 Homemaker’s Books by Dorothy Parkhurst, page 5 Betty Buys Her Silver Pattern by Clara Loewenstein, page 5 Association News by Marcia E. Turner, page 8 College Girls and Children by Nellie Goethe, page 10 Editorial News, page 11 Alumni News by Dorothy B. Anderson, page 1

You call it ‘Self-Exuberance,’ I call it ‘Bragging.’ Miscalibrated Predictions of Emotional Responses to Self-Promotion

People engage in self-promotional behavior because they want others to hold favorable images of them. Self-promotion, however, entails a tradeoff between conveying one’s positive attributes and being seen as bragging. We propose that people get this tradeoff wrong because they erroneously project their own feelings onto their interaction partners. As a consequence, people overestimate the extent to which recipients of their self-promotion will feel proud of and happy for them, and underestimate the extent to which recipients will feel annoyed (Experiment 1 and 2). Because people tend to self-promote excessively when trying to make a favorable impression on others, such efforts often backfire, causing targets of the self-promotion to view the self-promoter as less likeable and as a braggart (Experiment 3)