183 research outputs found
Multianalytical approach to characterize composition and degradation processes of synthetic high-fashion textiles from the Nanni Strada Design Studio archives
Synthetic textiles are constituents of heritage objects and garments often displayed in museum collections or preserved in archives, presenting unprecedented and specific conservation challenges. These issues need to be addressed assessing degradation processes, and developing targeted restoration and preventive conservation practices. The present work aims at characterizing the composition of high fashion garments and design textiles by Nanni Strada conserved in the archives of Nanni Strada Design Studio (Milan). To identify the chemical composition of the fibers used for the manufacturing, and to investigate the degradation processes affecting the objects, the materials were investigated by Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy (ATR-FTIR), Evolved Gas Analysis coupled to Mass Spectrometry (EGA-MS), and multi-shot Pyrolysis coupled to Gas Chromatography and Mass Spectrometry (Py-GC/MS). The results will contribute to a better knowledge of the chemical properties of the textiles produced in the 1970s, and to plan conservation and exhibition strategies
ABCD2, ABCD2-I, and OTTAWA scores for stroke risk assessment: a direct retrospective comparison
Transient ischemic attack (TIA) is a neurologic emergency characterized by cerebral ischemia eliciting a temporary focal neurological deficit. Many clinical prediction scores have been proposed to assess the risk of stroke after TIA; however, studies on their clinical validity and comparisons among them are scarce. The objective is to compare the accuracy of ABCD2, ABCD2-I, and OTTAWA scores in the prediction of a stroke at 7, 90 days, and 1 year in patients presenting with TIA. Single-centre, retrospective study including patients with TIA admitted to the Emergency Department of our third-level, University Hospital, between 2018 and 2019. Five hundred three patients were included. Thirty-nine (7.7%) had a stroke within 1 year from the TIA: 9 (1.7%) and 24 (4.7%) within 7 and 90 days, respectively. ABCD2, ABCD2-I, and OTTAWA scores were significantly higher in patients who developed a stroke. AUROCs ranged from 0.66 to 0.75, without statistically significant differences at each time-point. Considering the best cut-off of each score, only ABCD2 > 3 showed a sensitivity of 100% only in the prediction of stroke within 7 days. Among clinical items of each score, duration of symptoms, previous TIA, hemiparesis, speech disturbance, gait disturbance, previous cerebral ischemic lesions, and known carotid artery disease were independent predictors of stroke. Clinical scores have moderate prognostic accuracy for stroke after TIA. Considering the independent predictors for stroke, our study indicates the need to continue research and prompts the development of new tools on predictive scores for TIA
Membrane-binding peptides for extracellular vesicles on-chip analysis
Small extracellular vesicles (sEVs) present fairly distinctive lipid membrane features in the extracellular environment. These include high curvature, lipid-packing defects and a relative abundance in lipids such as phosphatidylserine and ceramide. sEV membrane could be then considered as a "universal" marker, alternative or complementary to traditional, characteristic, surface-associated proteins. Here, we introduce the use of membrane-sensing peptides as new, highly efficient ligands to directly integrate sEV capturing and analysis on a microarray platform. Samples were analysed by label-free, single-particle counting and sizing, and by fluorescence co-localisation immune staining with fluorescent anti-CD9/anti-CD63/anti-CD81 antibodies. Peptides performed as selective yet general sEV baits and showed a binding capacity higher than anti-tetraspanins antibodies. Insights into surface chemistry for optimal peptide performances are also discussed, as capturing efficiency is strictly bound to probes surface orientation effects. We anticipate that this new class of ligands, also due to the versatility and limited costs of synthetic peptides, may greatly enrich the molecular toolbox for EV analysis
Detectors for the James Webb Space Telescope Near-Infrared Spectrograph I: Readout Mode, Noise Model, and Calibration Considerations
We describe how the James Webb Space Telescope (JWST) Near-Infrared
Spectrograph's (NIRSpec's) detectors will be read out, and present a model of
how noise scales with the number of multiple non-destructive reads
sampling-up-the-ramp. We believe that this noise model, which is validated
using real and simulated test data, is applicable to most astronomical
near-infrared instruments. We describe some non-ideal behaviors that have been
observed in engineering grade NIRSpec detectors, and demonstrate that they are
unlikely to affect NIRSpec sensitivity, operations, or calibration. These
include a HAWAII-2RG reset anomaly and random telegraph noise (RTN). Using real
test data, we show that the reset anomaly is: (1) very nearly noiseless and (2)
can be easily calibrated out. Likewise, we show that large-amplitude RTN
affects only a small and fixed population of pixels. It can therefore be
tracked using standard pixel operability maps.Comment: 55 pages, 10 figure
CaracterĂsticas quĂmicas de um latossolo sob diferentes sistemas de produção no noroeste paulista.
Sistemas de manejo conservacionistas que tĂȘm o intuito de evitar o desgaste ou a degradação do solo vĂȘm sendo difundidos na agricultura. Este trabalho teve por objetivo avaliar as caracterĂsticas quĂmicas de um Latossolo sob sistema plantio direto, integração lavoura-pecuĂĄria e integração lavourapecuĂĄria- silvicultura, comparados a uma ĂĄrea de cerrado nativo, em Votuporanga, SP. Conclui-se que os sistemas de produção avaliados apresentaram, na fase inicial de implantação, caracterĂsticas quĂmicas desfavorĂĄveis ao desenvolvimento das culturas, com baixos teores de fĂłsforo e acidez elevada, semelhante a ĂĄrea de cerrado nativo, sendo necessĂĄrio a continuidade dos estudos por um perĂodo maior
Preliminary Integrated Chronostratigraphy of the AND-2A Core, ANDRILL Southern McMurdo Sound Project, Antarctica
We use all available chronostratigraphic constraints â biostratigraphy, magnetostratigraphy,
radioisotopic dates, strontium-isotope stratigraphy, and correlation of compositional and physical properties
to well-dated global or regional records â to construct a preliminary age model for ANDRILL SMS Projectâs
AND-2A drillcore (77°45.488âS, 165°16.605âE, 383.57 m water depth). These diverse chronostratigraphic
constraints are consistent with each other and are distributed throughout the 1138.54 m-thick section,
resulting in a well-constrained age model. The sedimentary succession comprises a thick early and middle
Miocene section below 224.82 mbsf and a condensed middle/late Miocene to Recent section above
this. The youngest sediments are Brunhes age (<0.781 Ma), as confirmed by a radioisotopic age of
0.691±0.049 Ma at 10.23 mbsf and the occurrence of sediments that have normal magnetic polarity down
to ~31.1 mbsf, which is interpreted to be the Brunhes/Matuyama reversal (0.781 Ma). The upper section
is punctuated by disconformities resulting from both discontinuous deposition and periods of extensive
erosion typical of sedimentary environments at the margin of a dynamic ice sheet. Additional breaks in
the section may be due to the influence of tectonic processes. The age model incorporates several major
hiatuses but their precise depths are still somewhat uncertain, as there are a large number of erosional
surfaces identified within the stratigraphic section. One or more hiatuses, which represent a total 7 to 8
million years of time missing from the sedimentary record, occur between about 50 mbsf and the base of
Lithostratigraphic Unit (LSU) 3 at 122.86 mbsf. Similarly, between about 145 mbsf and the base of LSU
4 at 224.82 mbsf, one or more hiatuses occur on which another 2 to 3 million years of the sedimentary
record is missing. Support for the presence of these hiatuses comes from a diatom assemblage that
constrains the age of the core from 44 to 50 mbsf to 2.06-2.84 Ma, two radioisotopic dates (11.4 Ma)
and a Srâisotope date (11.7 Ma) that indicate the interval from 127 to 145 mbsf was deposited between
11.4 and 11.7 Ma, and three diatom occurrence datums from between 225.38 and 278.55 mbsf that
constrain the age of this upper part of Lithostratigraphic Unit (LSU) 5 to 14.29 - 15.89 Ma. Below the
boundary between LSU 5 and 6 sedimentation was relatively continuous and rapid and the age model is
well-constrained by 9 diatom datums, seven 40Ar-39Ar dates, one Sr-isotope date, and 19 magnetozones.
Even so, short hiatuses (less than a few hundred thousand years) undoubtedly occur but are beyond
the resolution of current chronostratigraphic age constraints. Diatom first and last occurrence datums
provide particularly good age control from the top of LSU 6 down to 771.5 mbsf (in LSU 10), where
the First Occurrence (FO) of Thalassiosira praefraga (18.85 Ma) is observed. The diatom datum ages
are supported by radioisotopic dates of 17.30±0.31 Ma at 640.14 mbsf (in LSU 9) and 18.15±0.35 and
17.93±0.40 Ma for samples from 709.15 and 709.18 mbsf (in LSU 10), respectively, and 18.71±0.33 Ma
for a sample from 831.67 mbsf (in LSU 11). The sediments from 783.69 mbsf to the base of the hole
comprise two thick normal polarity magnetozones that bound a thinner reversed polarity magnetozone
(958.59 - 985.64 mbsf). This polarity sequence most likely encompasses Chrons C5En, C5Er, and C6n
(18.056 - 19.772 Ma or slightly older given uncertainties in this section of the geomagnetic polarity
timescale), but could be also be Chrons C6n, C6r, and C6An.1n (18.748 - 20.213 Ma). Either polarity
sequence is compatible with the 40Arâ39Ar age of 20.01±0.35 Ma obtained from single-grain analyses of
alkali feldspar from a tephra sample from a depth of 1093.02 mbsf, although the younger interpretation
allows a better fit with chronostratigraphic data up-core. Given this age model, the mean sedimentation
rate is about 18 cm/k.y. from the top of LSU 6 to the base of the hole.Published221-2202.2. Laboratorio di paleomagnetismoN/A or not JCRreserve
Central nervous system and muscular bundles preserved in a 240 million year old giant bristletail (Archaeognatha: Machilidae)
Among the incomparably diverse group of insects no cases of central nervous system (CNS) preservation have been so far described in compression fossils. A third of the fossil insects collected from a 240-239 million year old (Ma) level at Monte San Giorgio UNESCO World Heritage (SwitzerlandItaly) underwent phosphatization, resulting in the extraordinary preservation of soft tissues. Here we describe Gigamachilis triassicus gen. et sp. nov. (Archaeognatha: Machiloidea: Machilidae) that, with an estimated total length of similar to 80 millimeters, represents the largest apterygote insect ever recorded. The holotype preserves: (i) components of the CNS represented by four abdominal ganglia, optic lobes with neuropils and compound retina;(ii) muscular bundles. Moreover, G. triassicus, possessing morphological features that prompt its assignment to the extant archaeognathan ingroup Machilidae, places the origin of modern lineages to Middle Triassic. Interestingly, at Monte San Giorgio, in the same stratigraphic unit the modern morphology of G. triassicus co-occurs with the ancient one represented by Dasyleptus triassicus (Archaeognatha: dagger Monura). Comparing these two types of body organization we provide a new reconstruction of the possible character evolution leading towards modern archaeognathan forms, suggesting the acquisition of novel features in a lineage of apterygote insects during the Permian or the Lower Triassic
The Near-Infrared Spectrograph (NIRSpec) on the James Webb Space Telescope: I. Overview of the instrument and its capabilities
We provide an overview of the design and capabilities of the near-infrared
spectrograph (NIRSpec) onboard the James Webb Space Telescope. NIRSpec is
designed to be capable of carrying out low-resolution () prism
spectroscopy over the wavelength range m and higher resolution
( or ) grating spectroscopy over
m, both in single-object mode employing any one of five fixed
slits, or a 3.13.2 arcsec integral field unit, or in multiobject
mode employing a novel programmable micro-shutter device covering a
3.63.4~arcmin field of view. The all-reflective optical chain of
NIRSpec and the performance of its different components are described, and some
of the trade-offs made in designing the instrument are touched upon. The
faint-end spectrophotometric sensitivity expected of NIRSpec, as well as its
dependency on the energetic particle environment that its two detector arrays
are likely to be subjected to in orbit are also discussed
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The Near-Infrared Spectrograph (NIRSpec) on the James Webb Space Telescope: I. Overview of the instrument and its capabilities
We provide an overview of the design and capabilities of the near-infrared
spectrograph (NIRSpec) onboard the James Webb Space Telescope. NIRSpec is
designed to be capable of carrying out low-resolution () prism
spectroscopy over the wavelength range m and higher resolution
( or ) grating spectroscopy over
m, both in single-object mode employing any one of five fixed
slits, or a 3.13.2 arcsec integral field unit, or in multiobject
mode employing a novel programmable micro-shutter device covering a
3.63.4~arcmin field of view. The all-reflective optical chain of
NIRSpec and the performance of its different components are described, and some
of the trade-offs made in designing the instrument are touched upon. The
faint-end spectrophotometric sensitivity expected of NIRSpec, as well as its
dependency on the energetic particle environment that its two detector arrays
are likely to be subjected to in orbit are also discussed
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