Forschungsdatenmanagement als Herausforderung für Hochschulen und Hochschulbibliotheken

Eines der wichtigsten neuen Handlungsfelder der Forschung, das im Zuge der Digitalisierung von Information entstanden ist, ist das Management von Forschungsdaten. Die Hochschulen müssen sich darauf einstellen, ihren Wissenschaftlerinnen und Wissenschaftlern die notwendigen Strukturen und Services zur Verfügung zu stellen. Die in der Hochschulrektorenkonferenz (HRK) organisierten Leitungen der deutschen Hochschulen sehen darin eine zentrale Aufgabe. Die Universität Münster geht mit gutem Beispiel voran: In enger Zusammenarbeit mit der Hochschulleitung hat die Universitäts- und Landesbibliothek damit begonnen, Strukturen und Services zur Unterstützung des Forschungsdatenmanagements aufzubauen.One of the most important fields of action in research which is developing along with the digitalisation of information is research data management. The universities face the challenge of offering their researchers adequate structures and services. The managing boards of the German universities organised in the German Rectors’ Conference has identified this as a key task. The Westfälische Wilhelms-Universität Münster sets a good example: The University and Regional Library of Münster works closely together with the managing board of the university in order to establish structures and services supporting research data management

An Evolutionary Analysis of Insurance Markets

Since the seminal work by Rothschild and Stiglitz on competitive insurance markets under adverse selection the problem of non-existence of equilibrium has puzzled many economists. In this paper we approach this problem from an evo- lutionary point of view. In a dynamic model insurance companies remove loss- making contracts from the market and copy prot-making ones. Occasionally, they also experiment, adding new contracts or removing current ones arbitrarily. We show that the Rothschild-Stiglitz outcome arises in the long run if it consti- tutes an equilibrium in the static framework, but also if it is not an equilibrium, provided that rms only experiment with contracts in the vicinity of their current portfolio.

Integrierte Bereitstellung, einheitlicher Zugang und individuelle Verteilung:Informations-Management einer großen Universität

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Technology experience café - enabling technology - driven social innovation for an ageing society

Effective technology innovation process management in the context of active healthy ageing has the potential to improve older adults’ quality of life, allowing them to maintain their independence and age in their own homes for longer. But as older adults significantly differ from the general population in technology use and its impact on their quality of life, tools are needed that (1) involve this target group into the innovation process, as well as (2) capture the diverse needs of technology for various stakeholders involved in this process. This paper presents the framework called Technology Experience Café (TEC), developed within the European project SIforAGE, answering exactly this need. Detailed information on the methodology and its implementation in five sites, in four different countries across Europe, focusing on participating stakeholders, general design of the TEC, and used evaluation tools, is provided. Preliminary results show, that (1) the target group’s perception of the TEC as a framework was thoroughly positive and TECs had a positive impact on older adults’ technology related attitudes and (2) that stakeholders’ benefits affiliated with their involvement in the TECs are manifold. Implications and limitations are discussed

Crossing borders of material science – a new approach of aerogel preparation for electron microscopy

A new method for the embedding and preparation of organic aerogels for electron mciroscopic Analysis like Crosssectioning, Lamella preparation, FIB-Tomography and Transmissio Electron Microscop

Validity of the Polar V800 heart rate monitor to measure RR intervals at rest

Purpose To assess the validity of RR intervals and short-term heart rate variability (HRV) data obtained from the Polar V800 heart rate monitor, in comparison to an electrocardiograph (ECG). Method Twenty participants completed an active orthostatic test using the V800 and ECG. An improved method for the identification and correction of RR intervals was employed prior to HRV analysis. Agreement of the data was assessed using intra-class correlation coefficients (ICC), Bland–Altman limits of agreement (LoA), and effect size (ES). Results A small number of errors were detected between ECG and Polar RR signal, with a combined error rate of 0.086 %. The RR intervals from ECG to V800 were significantly different, but with small ES for both supine corrected and standing corrected data (ES 0.999 for both supine and standing corrected intervals. When analysed with the same HRV software no significant differences were observed in any HRV parameters, for either supine or standing; the data displayed small bias and tight LoA, strong ICC (>0.99) and small ES (≤0.029). Conclusions The V800 improves over previous Polar models, with narrower LoA, stronger ICC and smaller ES for both the RR intervals and HRV parameters. The findings support the validity of the Polar V800 and its ability to produce RR interval recordings consistent with an ECG. In addition, HRV parameters derived from these recordings are also highly comparable

The surface science of quasicrystals

The surfaces of quasicrystals have been extensively studied since about 1990. In this paper we review work on the structure and morphology of clean surfaces, and their electronic and phonon structure. We also describe progress in adsorption and epitaxy studies. The paper is illustrated throughout with examples from the literature. We offer some reflections on the wider impact of this body of work and anticipate areas for future development. (Some figures in this article are in colour only in the electronic version

Studies of colossal magnetoresistive oxides with radioactive isotopes

We propose to study Colossal Magnetoresistive (CMR) oxides with several nuclear techniques, which use radioactive elements at ISOLDE. Our aim is to provide local and element selective information on some of the doping mechanisms that rule electronic interactions and magnetoresistance, in a complementary way to the use of conventional characterisation techniques. Three main topics are proposed: \\ \\ a) Studies of local [charge and] structural modifications in antiferromagnetic LaMnO$_{3+ \delta}$ and La$_{1-x}$R$_{x}$MnO$_{3}$ with R=Ca and Cd, doped ferromagnetic systems with competing interactions: - research on the lattice site and electronic characterisation of the doping element. \\ \\ b) Studies of self doped La$_{x}$R$_{1-x}$MnO$_{3+\delta}$ systems, with oxygen and cation non-stoichiometry: -learning the role of defects in the optimisation of magnetoresistive properties. \\ \\ c) Probing the disorder and quenched random field effects in the vicinity of the charge or orbital Ordered/Ferromagnetic phase instability: - Investigating the local environment of ions at the Mn site, which trigger the ferromagnetic phase. Our approach to study these problems, combines complementary techniques such as Perturbed Angular Correlation, Emission Channeling and Electrical/Magnetic Measurements in pellets, single crystals and high quality thin films of CMR oxides doped with radioactive isotopes. Preliminary results obtained in La Cd MnO$_{3+x}$ pellets and thin films implanted with $^{111m}$Cd are also presented

Determination of total x-ray absorption coefficient using non-resonant x-ray emission

An alternative measure of x-ray absorption spectroscopy (XAS) called inverse partial fluorescence yield (IPFY) has recently been developed that is both bulk sensitive and free of saturation effects. Here we show that the angle dependence of IPFY can provide a measure directly proportional to the total x-ray absorption coefficient, µ(E). In contrast, fluorescence yield (FY) and electron yield (EY) spectra are offset and/or distorted from µ(E) by an unknown and difficult to measure amount. Moreover, our measurement can determine µ(E) in absolute units with no free parameters by scaling to µ(E) at the non-resonant emission energy. We demonstrate this technique with measurements on NiO and NdGaO3. Determining µ(E) across edge-steps enables the use of XAS as a non-destructive measure of material composition. In NdGaO3, we also demonstrate the utility of IPFY for insulating samples, where neither EY or FY provide reliable spectra due to sample charging and self-absorption effects, respectively

An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells

Stimulation of renal collecting duct principal cells with antidiuretic hormone (arginine-vasopressin, AVP) results in inhibition of the small GTPase RhoA and the enrichment of the water channel aquaporin-2 (AQP2) in the plasma membrane. The membrane insertion facilitates water reabsorption from primary urine and fine-tuning of body water homeostasis. Rho guanine nucleotide exchange factors (GEFs) interact with RhoA, catalyze the exchange of GDP for GTP and thereby activate the GTPase. However, GEFs involved in the control of AQP2 in renal principal cells are unknown. The A-kinase anchoring protein, AKAP-Lbc, possesses GEF activity, specifically activates RhoA, and is expressed in primary renal inner medullary collecting duct principal (IMCD) cells. Through screening of 18,431 small molecules and synthesis of a focused library around one of the hits, we identified an inhibitor of the interaction of AKAP-Lbc and RhoA. This molecule, Scaff10-8, bound to RhoA, inhibited the AKAP-Lbc-mediated RhoA activation but did not interfere with RhoA activation through other GEFs or activities of other members of the Rho family of small GTPases, Rac1 and Cdc42. Scaff10-8 promoted the redistribution of AQP2 from intracellular vesicles to the periphery of IMCD cells. Thus, our data demonstrate an involvement of AKAP-Lbc-mediated RhoA activation in the control of AQP2 trafficking