19,445 research outputs found
On the nonlinear statistics of range image patches
In [A. B. Lee, K. S. Pedersen, and D. Mumford, Int. J. Comput. Vis., 54 (2003), pp. 83–103], the authors study the distributions of 3 × 3 patches from optical images and from range images. In [G. Carlsson, T. Ishkanov, V. de Silva, and A. Zomorodian, Int. J. Comput. Vis., 76 (2008), pp.
1–12], the authors apply computational topological tools to the data set of optical patches studied by Lee, Pedersen, and Mumford and find geometric structures for high density subsets. One high density subset is called the primary circle and essentially consists of patches with a line separating a light and a dark region. In this paper, we apply the techniques of Carlsson et al. to range patches.
By enlarging to 5×5 and 7×7 patches, we find core subsets that have the topology of the primary circle, suggesting a stronger connection between optical patches and range patches than was found by Lee, Pedersen, and Mumford
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Sand Penetration By High-Speed Projectiles
Tungsten projectiles were shot into sand at velocities between 600 and 2200 m/s. Penetration was maximum at about 775 m/s. Below that velocity, projectiles were apparently stabilized by a fin set. Above that velocity, projectiles were broken by transverse loads. High-speed penetration resulted in comminution of sand particles, reducing their size by about 1000 times.Mechanical Engineerin
Inflammation and changes in cytokine levels in neurological feline infectious peritonitis.
Feline infectious peritonitis (FIP) is a progressive, fatal, predominantly Arthus-type immune-mediated disease that is triggered when cats are infected with a mutant enteric coronavirus. The disease presents variably with multiple organ failure, seizures, generalized effusion, or shock. Neurological FIP is clinically and pathologically more homogeneous than systemic 'wet' or 'dry' FIP; thus, comparison of cytokine profiles from cats with neurological FIP, wet FIP, and non-FIP neurological disease may provide insight into some baseline characteristics relating to the immunopathogenesis of neurological FIP. This study characterizes inflammation and changes in cytokines in the brain tissue of FIP-affected cats. Cellular infiltrates in cats with FIP included lymphocytes, plasma cells, neutrophils, macrophages, and eosinophils. IL-1 beta, IL-6, IL-12, IL-18, TNF-alpha, macrophage inhibitory protein (MIP)-1 alpha, and RANTES showed no upregulation in the brains of control cats, moderate upregulation in neurological FIP cats, and very high upregulation in generalized FIP cats. Transcription of IFN-gamma appeared upregulated in cats with systemic FIP and slightly downregulated in neurological FIP. In most cytokines tested, variance was extremely high in generalized FIP and much less in neurological FIP. Principal components analysis was performed in order to find the least number of 'components' that would summarize the cytokine profiles in cats with neurological FIP. A large component of the variance (91.7%) was accounted for by levels of IL-6, MIP-1 alpha, and RANTES. These findings provide new insight into the immunopathogenesis of FIP and suggest targets for immune therapy of this disease
Ptychographic X-ray computed tomography of extended colloidal networks in food emulsions
As a main structural level in colloidal food materials, extended colloidal
networks are important for texture and rheology. By obtaining the 3D
microstructure of the network, macroscopic mechanical properties of the
material can be inferred. However, this approach is hampered by the lack of
suitable non-destructive 3D imaging techniques with submicron resolution.
We present results of quantitative ptychographic X-ray computed tomography
applied to a palm kernel oil based oil-in-water emulsion. The measurements were
carried out at ambient pressure and temperature. The 3D structure of the
extended colloidal network of fat globules was obtained with a resolution of
around 300 nm. Through image analysis of the network structure, the fat globule
size distribution was computed and compared to previous findings. In further
support, the reconstructed electron density values were within 4% of reference
values.Comment: 19 pages, 4 figures, to be published in Food Structur
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Elevated fetal steroidogenic activity in autism
Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor. Utilizing the Danish Historic Birth Cohort and Danish Psychiatric Central Register, we identified all amniotic fluid samples of males born between 1993 and 1999 who later received ICD-10 (International Classification of Diseases, 10th Revision) diagnoses of autism, Asperger syndrome or PDD-NOS (pervasive developmental disorder not otherwise specified) (n=128) compared with matched typically developing controls. Concentration levels of Δ4 sex steroids (progesterone, 17α-hydroxy-progesterone, androstenedione and testosterone) and cortisol were measured with liquid chromatography tandem mass spectrometry. All hormones were positively associated with each other and principal component analysis confirmed that one generalized latent steroidogenic factor was driving much of the variation in the data. The autism group showed elevations across all hormones on this latent generalized steroidogenic factor (Cohen's d=0.37, P=0.0009) and this elevation was uniform across ICD-10 diagnostic label. These results provide the first direct evidence of elevated fetal steroidogenic activity in autism. Such elevations may be important as epigenetic fetal programming mechanisms and may interact with other important pathophysiological factors in autism
On the existence of impurity bound excitons in one-dimensional systems with zero range interactions
We consider a three-body one-dimensional Schr\"odinger operator with zero
range potentials, which models a positive impurity with charge
interacting with an exciton. We study the existence of discrete eigenvalues as
is varied. On one hand, we show that for sufficiently small
there exists a unique bound state whose binding energy behaves like ,
and we explicitly compute its leading coefficient. On the other hand, if
is larger than some critical value then the system has no bound
states
Inducing spin-dependent tunneling to probe magnetic correlations in optical lattices
We suggest a simple experimental method for probing antiferromagnetic spin
correlations of two-component Fermi gases in optical lattices. The method
relies on a spin selective Raman transition to excite atoms of one spin species
to their first excited vibrational mode where the tunneling is large. The
resulting difference in the tunneling dynamics of the two spin species can then
be exploited, to reveal the spin correlations by measuring the number of doubly
occupied lattice sites at a later time. We perform quantum Monte Carlo
simulations of the spin system and solve the optical lattice dynamics
numerically to show how the timed probe can be used to identify
antiferromagnetic spin correlations in optical lattices.Comment: 5 pages, 5 figure
Thermodynamics of Heat Shock Response
Production of heat shock proteins are induced when a living cell is exposed
to a rise in temperature. The heat shock response of protein DnaK synthesis in
E.coli for temperature shifts from temperature T to T plus 7 degrees,
respectively to T minus 7 degrees is measured as function of the initial
temperature T. We observe a reversed heat shock at low T. The magnitude of the
shock increases when one increase the distance to the temperature , thereby mimicking the non monotous stability of proteins at low
temperature. Further we found that the variation of the heat shock with T
quantitatively follows the thermodynamic stability of proteins with
temperature. This suggest that stability related to hot as well as cold
unfolding of proteins is directly implemented in the biological control of
protein folding. We demonstrate that such an implementation is possible in a
minimalistic chemical network.Comment: To be published in Physical Review Letter
Tsirelson's problem and Kirchberg's conjecture
Tsirelson's problem asks whether the set of nonlocal quantum correlations
with a tensor product structure for the Hilbert space coincides with the one
where only commutativity between observables located at different sites is
assumed. Here it is shown that Kirchberg's QWEP conjecture on tensor products
of C*-algebras would imply a positive answer to this question for all bipartite
scenarios. This remains true also if one considers not only spatial
correlations, but also spatiotemporal correlations, where each party is allowed
to apply their measurements in temporal succession; we provide an example of a
state together with observables such that ordinary spatial correlations are
local, while the spatiotemporal correlations reveal nonlocality. Moreover, we
find an extended version of Tsirelson's problem which, for each nontrivial Bell
scenario, is equivalent to the QWEP conjecture. This extended version can be
conveniently formulated in terms of steering the system of a third party.
Finally, a comprehensive mathematical appendix offers background material on
complete positivity, tensor products of C*-algebras, group C*-algebras, and
some simple reformulations of the QWEP conjecture.Comment: 57 pages, to appear in Rev. Math. Phy
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