MUSE observations of a changing-look AGN I: The re-appearance of the broad emission lines

Optical changing-look Active Galactic Nuclei (AGN) are a class of sources that change type within a short timescale of years or decades. This change is characterised by the appearance or disappearance of broad emission lines, often associated with dramatic AGN continuum flux changes that are orders of magnitude larger than those expected from typical AGN variability. In this work we study for the first time the host galaxy of a changing-look AGN, Mrk 590, using high spatial resolution optical and near-infrared observations. We discover that after ~ 10 yr absence, the optical broad emission lines of Mrk 590 have reappeared. The AGN optical continuum flux however, is still ~ 10 times lower than that observed during the most luminous state in the 1990s. The host galaxy shows a 4.5 kpc radius star-forming ring with knots of ionised and cold molecular gas emission. Extended ionised and warm molecular gas emission are detected in the nucleus, indicating that there is a reservoir of gas as close as 60 pc from the black hole. We observe a nuclear gas spiral between radii r ~ 0.5 - 2 kpc, which has been suggested as a dynamical mechanism able to drive the necessary gas to fuel AGN. We also discover blue-shifted and high velocity dispersion [O III] emission out to a radius of 1 kpc, tracing a nuclear gas outflow. The gas dynamics in Mrk 590 suggest a complex balance between gas inflow and outflow in the nucleus of the galaxy.Comment: Accepted for publication in MNRA

Fever and Generalised Lymphadenopathy in an HIV-Positive Patient: a Diagnostic Challenge

Fever and generalised lymphadenopathy is a common presentation of a variety of diseases and a thorough investigation is often necessary for appropriate diagnosis.We present a 53-year-old male patient admitted with fever, weight loss of 15 kg in 3 months and abdominal discomfort. Examination was only remarkable for axillary and inguinal lymphadenopathy. Blood tests showed normocytic normochromic anaemia, cholestasis and a previously unknown HIV-1 infection with lymphocyte CD4 +count of 239 cells/mm(3) and viral load 3.172.370 copies/mL. A body CT scan showed multiple axillary, mediastinal, lumbar, aortic, iliac and pelvic lymphadenopathy as well as hepatosplenomegaly. An excisional biopsy of the left axillary lymphadenopathy was performed and histology ultimately revealed multicentric Castleman's disease associated with Human Herpes Virus-8. After initiation of antiretroviral therapy, rituximab was given and progressive clinical improvement occurred.info:eu-repo/semantics/publishedVersio

Approch to the knowledge of Coccinellidade (Coleoptera) species diversity of Madeira and Porto Santo Islands.

Proceedings of the 8th International Symposium on Ecology of Aphidophaga: Biology, Ecology and Behaviour of Aphidophagous Insects.We present a list of coccinellids collected in Madeira archipelago and notice the presence of two new species; of Scymnini; Scymnus (Scymnus) abietis (Paykull) and Nephus hiekei Fürsch. We analyse the distribution and abundance at the community level, using the following measures: species richness index, abundance and relative abundance, similarity index, diversity, and evenness. 13 species from 3 families were recorded. Hippodamia variegata was the most abundant one with 29.7 % of the 141 specimens collected. Two main groups of relative abundance were identified. The first group included the 6 most common H. variegata, S. interruptus, C. arcuatus, C. septempunctata, S. levaillanti and R. litura and the second one included S. abietis, L. lophante and R. chrysomeloides. Diversity index values are relatively high. The 6 most common species comprised more than 90 % of the individuals without a very different relative abundance. Many factors other than extinction and immigration could explain the variation of the number of species on islands. The highest number of species collected in Madeira island, compared to Porto Santo, could be related with its higher elevation, soil and substrate types, plant species richness, number of habitat, habitats diversity, structure and heterogeneity of the former

Disordered two-dimensional superconductors: roles of temperature and interaction strength

We have considered the half-filled disordered attractive Hubbard model on a square lattice, in which the on-site attraction is switched off on a fraction $f$ of sites, while keeping a finite $U$ on the remaining ones. Through Quantum Monte Carlo (QMC) simulations for several values of $f$ and $U$, and for system sizes ranging from $8\times 8$ to $16\times 16$, we have calculated the configurational averages of the equal-time pair structure factor $P_s$, and, for a more restricted set of variables, the helicity modulus, $\rho_s$, as functions of temperature. Two finite-size scaling {\it ansatze} for $P_s$ have been used, one for zero-temperature and the other for finite temperatures. We have found that the system sustains superconductivity in the ground state up to a critical impurity concentration, $f_c$, which increases with $U$, at least up to U=4 (in units of the hopping energy). Also, the normalized zero-temperature gap as a function of $f$ shows a maximum near $f\sim 0.07$, for $2\lesssim U\lesssim 6$. Analyses of the helicity modulus and of the pair structure factor led to the determination of the critical temperature as a function of $f$, for $U=3,$ 4 and 6: they also show maxima near $f\sim 0.07$, with the highest $T_c$ increasing with $U$ in this range. We argue that, overall, the observed behavior results from both the breakdown of CDW-superconductivity degeneracy and the fact that free sites tend to "push" electrons towards attractive sites, the latter effect being more drastic at weak couplings.Comment: 9 two-column pages, 14 figures, RevTe

Digital Competence and University Teachers’ Conceptions about Teaching. A Structural Causal Model

Introduction: University teachers, in their ongoing scientific and pedagogical updating, must master the new methodologies and trends in their professional field. ICT’s importance for any person requires ethical responsibility, and it is incumbent on the educational professionals to preserve, improve and update their level of digital competence, and so improve learning and teaching. Method: This study uses a representative sample of 186 university teachers and follows the quantitative descriptive survey method. Two questionnaires were applied (CEE-ACUTIC). The first identified the approach for the transmission of information or the construction of knowledge, and the second measured attitude, knowledge and use of ICT. Results: A causal model of structural equations of maximum likelihood was run. We highlight the positive and significant relationship between the teaching approach oriented to the construction of knowledge and the use of ICTs (β = 0.17, p < 0.01) and, in another sense, a statistically significant but negative relationship between the use of ICTs and the teaching approach focused on the transmission of information (β = −0.16, p < 0.05). Discussion: It is empirically confirmed that the teaching approach conditions the use of technologies for teaching. There is no research in other contexts showing a causal relationship between teaching approaches and digital teaching competence.This research was funded by the Fundación Séneca. Agencia de Ciencia y Tecnología de la Región de Murcia (Spain) with the competitive project code 20638/JLI/18 “Competencias docentes y métodos activos de aprendizaje. Una investigación evaluativa con el profesorado en formación de ciencias sociales”

A Ampla Defesa nos Processos Administrativos Disciplinares

O presente trabalho se ocupará de analisar a incidência dos princípios do contraditório e da ampla defesa em sede de processo administrativo disciplinar e as implicações decorrentes da edição da Súmula Vinculante n° 5, sob os aspectos formal e material. Para que tenhamos esse objetivo alcançado, será abordado de forma ampla a doutrina processual que regula os processos em geral, em especial os processos administrativos, até chegarmos ao processo administrativo disciplinar, onde a problemática em torno da falta de obrigatoriedade de defesa técnica será analisada sob o ponto de vista formal e material. Os princípios e garantias constitucionais do contraditório e da ampla defesa no processo administrativo disciplinar visam garantir uma carreira sólida para os servidores em geral, sem que os mesmos passem pelo constrangimento da perda de cargo efetivo, e sem a oportunidade de se defenderem, ou demitidos ou exonerados, sem o devido processo legal, e ao sabor da vaidade dos que detém o poder. No entanto, para ser servidor público, não necessariamente, o cidadão precisa saber se defender diante de um possível processo administrativo disciplinar. Dessa forma, questiona-se: com a falta de defesa técnica de um advogado no processo administrativo disciplinar, deixa-se de aplicar os meios legais para que se promova a justiça e, passa-se a prejudicar o servidor indiciado? Diante disso o presente estudo irá contribuir ao debate junto à Administração Pública com o objetivo de melhor se compreender as técnicas de organização, atos, fatos, e procedimentos que a dão funcionalidade garantindo aos servidores públicos o devido processo legal e especificamente os princípios e garantias constitucionais da ampla defesa e do contraditório

Luttinger liquid superlattices

We calculate the correlation functions and the DC conductivity of Luttinger liquid superlattices, modeled by a repeated pattern of interacting and free Luttinger liquids. In a specific realization, where the interacting subsystem is a Hubbard chain, the system exhibits a rich phase diagram with four different phases: two metals and two compressible insulators. In general, we find that the effective low energy description amalgamates features of both types of liquids in proportion to their spatial extent, suggesting the interesting possibility of `engineered' Luttinger liquids.Comment: RevTeX, 5 pages, 3 figure

PHF2 regulates homology-directed DNA repair by controlling the resection of DNA double strand breaks

Post-translational histone modifications and chromatin remodelling play a critical role controlling the integrity of the genome. Here, we identify histone lysine demethylase PHF2 as a novel regulator of the DNA damage response by regulating DNA damage-induced focus formation of 53BP1 and BRCA1, critical factors in the pathway choice for DNA double strand break repair. PHF2 knockdown leads to impaired BRCA1 focus formation and delays the resolution of 53BP1 foci. Moreover, irradiation-induced RPA phosphorylation and focus formation, as well as localization of CtIP, required for DNA end resection, to sites of DNA lesions are affected by depletion of PHF2. These results are indicative of a defective resection of double strand breaks and thereby an impaired homologous recombination upon PHF2 depletion. In accordance with these data, Rad51 focus formation and homology-directed double strand break repair is inhibited in cells depleted for PHF2. Importantly, we demonstrate that PHF2 knockdown decreases CtIP and BRCA1 protein and mRNA levels, an effect that is dependent on the demethylase activity of PHF2. Furthermore, PHF2-depleted cells display genome instability and are mildly sensitive to the inhibition of PARP. Together these results demonstrate that PHF2 promotes DNA repair by homologous recombination by controlling CtIP-dependent resection of double strand breaks.España Ministerio de Ciencia e Innovacion SAF2016-80626-REspaña, Fundación Canaria Instituto de Investigación Sanitaria de Canarias (FIISC) [PIFUN16/18