111 research outputs found
Experimental Evidence for Quantum Interference and Vibrationally Induced Decoherence in Single-Molecule Junctions
We analyze quantum interference and decoherence effects in single-molecule
junctions both experimentally and theoretically by means of the mechanically
controlled break junction technique and density-functional theory. We consider
the case where interference is provided by overlapping quasi-degenerate states.
Decoherence mechanisms arising from the electronic-vibrational coupling
strongly affect the electrical current flowing through a single-molecule
contact and can be controlled by temperature variation. Our findings underline
the all-important relevance of vibrations for understanding charge transport
through molecular junctions.Comment: 5 pages, 4 figure
Genotyping Validates the Efficacy of Photographic Identification in a Capture-Mark-Recapture Study Based on the Head Scale Patterns of the Prairie Lizard (\u3ci\u3eSceloporus consobrinus\u3c/i\u3e)
Population studies often incorporate captureâmarkârecapture (CMR) techniques to gather information on longâterm biological and demographic characteristics. A fundamental requirement for CMR studies is that an individual must be uniquely and permanently marked to ensure reliable reidentification throughout its lifespan. Photographic identification involving automated photographic identification software has become a popular and efficient noninvasive method for identifying individuals based on natural markings. However, few studies have (a) robustly assessed the performance of automated programs by using a doubleâmarking system or (b) determined their efficacy for longâterm studies by incorporating multiâyear data. Here, we evaluated the performance of the program Interactive Individual Identification System (I3S) by crossâvalidating photographic identifications based on the head scale pattern of the prairie lizard (Sceloporus consobrinus) with individual microsatellite genotyping (N = 863). Further, we assessed the efficacy of the program to identify individuals over time by comparing error rates between withinâyear and betweenâyear recaptures. Recaptured lizards were correctly identified by I3S in 94.1% of cases. We estimated a false rejection rate (FRR) of 5.9% and a false acceptance rate (FAR) of 0%. By using I3S, we correctly identified 97.8% of withinâyear recaptures (FRR = 2.2%; FAR = 0%) and 91.1% of betweenâyear recaptures (FRR = 8.9%; FAR = 0%). Misidentifications were primarily due to poor photograph quality (N = 4). However, two misidentifications were caused by indistinct scale configuration due to scale damage (N = 1) and ontogenetic changes in head scalation between capture events (N = 1). We conclude that automated photographic identification based on head scale patterns is a reliable and accurate method for identifying individuals over time. Because many lizard or reptilian species possess variable head squamation, this method has potential for successful application in many species
Quantum transport through STM-lifted single PTCDA molecules
Using a scanning tunneling microscope we have measured the quantum
conductance through a PTCDA molecule for different configurations of the
tip-molecule-surface junction. A peculiar conductance resonance arises at the
Fermi level for certain tip to surface distances. We have relaxed the molecular
junction coordinates and calculated transport by means of the Landauer/Keldysh
approach. The zero bias transmission calculated for fixed tip positions in
lateral dimensions but different tip substrate distances show a clear shift and
sharpening of the molecular chemisorption level on increasing the STM-surface
distance, in agreement with experiment.Comment: accepted for publication in Applied Physics
A Mixture of âCheatsâ and âCo-Operatorsâ Can Enable Maximal Group Benefit
It is commonly assumed that the world would be best off if everyone co-operates. Experimental and mathematical analysis of âco-operationâ in yeast show why this isn't always the case
Green function techniques in the treatment of quantum transport at the molecular scale
The theoretical investigation of charge (and spin) transport at nanometer
length scales requires the use of advanced and powerful techniques able to deal
with the dynamical properties of the relevant physical systems, to explicitly
include out-of-equilibrium situations typical for electrical/heat transport as
well as to take into account interaction effects in a systematic way.
Equilibrium Green function techniques and their extension to non-equilibrium
situations via the Keldysh formalism build one of the pillars of current
state-of-the-art approaches to quantum transport which have been implemented in
both model Hamiltonian formulations and first-principle methodologies. We offer
a tutorial overview of the applications of Green functions to deal with some
fundamental aspects of charge transport at the nanoscale, mainly focusing on
applications to model Hamiltonian formulations.Comment: Tutorial review, LaTeX, 129 pages, 41 figures, 300 references,
submitted to Springer series "Lecture Notes in Physics
Oxygen dependence of metabolic fluxes and energy generation of Saccharomyces cerevisiae CEN.PK113-1A
<p>Abstract</p> <p>Background</p> <p>The yeast <it>Saccharomyces cerevisiae </it>is able to adjust to external oxygen availability by utilizing both respirative and fermentative metabolic modes. Adjusting the metabolic mode involves alteration of the intracellular metabolic fluxes that are determined by the cell's multilevel regulatory network. Oxygen is a major determinant of the physiology of <it>S. cerevisiae </it>but understanding of the oxygen dependence of intracellular flux distributions is still scarce.</p> <p>Results</p> <p>Metabolic flux distributions of <it>S. cerevisiae </it>CEN.PK113-1A growing in glucose-limited chemostat cultures at a dilution rate of 0.1 h<sup>-1 </sup>with 20.9%, 2.8%, 1.0%, 0.5% or 0.0% O<sub>2 </sub>in the inlet gas were quantified by <sup>13</sup>C-MFA. Metabolic flux ratios from fractional [U-<sup>13</sup>C]glucose labelling experiments were used to solve the underdetermined MFA system of central carbon metabolism of <it>S. cerevisiae</it>.</p> <p>While ethanol production was observed already in 2.8% oxygen, only minor differences in the flux distribution were observed, compared to fully aerobic conditions. However, in 1.0% and 0.5% oxygen the respiratory rate was severely restricted, resulting in progressively reduced fluxes through the TCA cycle and the direction of major fluxes to the fermentative pathway. A redistribution of fluxes was observed in all branching points of central carbon metabolism. Yet only when oxygen provision was reduced to 0.5%, was the biomass yield exceeded by the yields of ethanol and CO<sub>2</sub>. Respirative ATP generation provided 59% of the ATP demand in fully aerobic conditions and still a substantial 25% in 0.5% oxygenation. An extensive redistribution of fluxes was observed in anaerobic conditions compared to all the aerobic conditions. Positive correlation between the transcriptional levels of metabolic enzymes and the corresponding fluxes in the different oxygenation conditions was found only in the respirative pathway.</p> <p>Conclusion</p> <p><sup>13</sup>C-constrained MFA enabled quantitative determination of intracellular fluxes in conditions of different redox challenges without including redox cofactors in metabolite mass balances. A redistribution of fluxes was observed not only for respirative, respiro-fermentative and fermentative metabolisms, but also for cells grown with 2.8%, 1.0% and 0.5% oxygen. Although the cellular metabolism was respiro-fermentative in each of these low oxygen conditions, the actual amount of oxygen available resulted in different contributions through respirative and fermentative pathways.</p
Metallic, magnetic and molecular nanocontacts
Scanning tunnelling microscopy and break-junction experiments realize metallic and molecular nanocontacts that act as ideal one-dimensional channels between macroscopic electrodes. Emergent nanoscale phenomena typical of these systems encompass structural, mechanical, electronic, transport, and magnetic properties. This Review focuses on the theoretical explanation of some of these properties obtained with the help of first-principles methods. By tracing parallel theoretical and experimental developments from the discovery of nanowire formation and conductance quantization in gold nanowires to recent observations of emergent magnetism and Kondo correlations, we exemplify the main concepts and ingredients needed to bring together ab initio calculations and physical observations. It can be anticipated that diode, sensor, spin-valve and spin-filter functionalities relevant for spintronics and molecular electronics applications will benefit from the physical understanding thus obtained
Regional and sectoral varieties of capitalism
This study seeks to go beneath the generalizations that constitute characterizations of national economies in order to examine local and sectoral diversity - in particular, forms of capitalist organization at the level of localized sectors. It reports on the findings of research based on detailed case histories of local economies in four different types of production: modernized craft manufacturing (furniture), mass production (motor vehicles), high-technology production (biopharmaceuticals) and high-tech services (television film-making). In each case a local economy in Germany (usually seen counter-factually as an example of a particularly national system) was compared with one elsewhere in Europe: respectively, southern Sweden, Hungary (compared with eastern Germany) and the UK (for two studies).
In the analysis, companies act rationally in response to sector-specific challenges, being partly bound by the existing institutional framework that they encounter, but partly acting to alter it. Two possibilities are distinguished and found in the cases. In the first (structurally conservative) case, arrangements of governance in the national innovation and production system prove to be beneficial for the companies and their aim to stand up to international competition. Insofar as national institutions help companies to deal with competition on their markets, they will probably try to preserve these arrangements. In the second (innovative) case, companies turn away from the national context and develop their own local governance structure. If the national institutional structure is seen as not adequate or 'non-fitting' to deal with sectorally specific terms of competition, then the internal and external coordination of companies - in reaction to challenges posed by the market - is likely to deviate from the national structure. In some instances evidence of 'creative incoherence', where local deviation from the national model provides a creative impulse, is found
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Marine Hydrokinetic Turbine Power-Take-Off Design for Optimal Performance and Low Impact on Cost-of-Energy: Preprint
Marine hydrokinetic devices are becoming a popular method for generating marine renewable energy worldwide. These devices generate electricity by converting the kinetic energy of moving water, wave motion or currents, into electrical energy through the use of a power-take-off (PTO) system. Most PTO systems incorporate a mechanical or hydraulic drivetrain, power generator, and electric control/conditioning system to deliver the generated electric power to the grid at the required state. Like wind turbine applications, the PTO system must be designed for high reliability, good efficiency, and long service life with reasonable maintenance requirements, low cost, and an appropriate mechanical design for anticipated applied steady and unsteady loads. The ultimate goal of a PTO design is high efficiency and low maintenance and cost, with a low impact on the device cost-of-energy (CoE)
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