480 research outputs found
New Formulas and Predictions for Running Masses at Higher Scales in MSSM
Including contributions of scale-dependent vacuum expectation values of Higgs
scalars, we derive new one-loop formulas analytically for running quark-lepton
masses at higher scales in MSSM. Apart from the gauge-coupling dependence being
different from earlier formulas, the third-generation- Yukawa-coupling effects
are absent in the masses of the first two generations. While predicting the
masses and numerically, we also include two-loop effects.Comment: 9 pages Latex.Typos correcte
Precision and uncertainties in mass scale predictions in SUSY SO(10) with SU(2)_L x SU(2)_R x U(1)_{B-L} x SU(3)_C intermediate breaking
In a class of SUSY SO(10) with
intermediate gauge symmetry, we observe that the
prediction on the unification mass is unaffected by
Planck-scale-induced gravitational and intermediate-scale-threshold effects,
although the intermediate scale itself is subject to such corrections.
In particular, without invoking the presence of additional lighter scalar
degrees of freedom but including plausible and reasonable threshold effects, we
find that interesting solutions for neutrino physics corresponding to
GeV and GeV are
permitted in the minimal models. Possibilities of low-mass right-handed gauge
bosons corresponding to TeV consistent with the CERN-LEP data
are pointed out in a number of models when threshold effects are included using
effective mass parameters.Comment: 12 pages including 7 tables (Typos corrected as per the published
version
Study of the Transition Temperature of Mohr's Salt Analogue of Mn(II) by Distribution Measurement
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Low Resource FPGA Based Time-to-Digital Converter
For the precise measurement of the time difference between the arrival of different signals coming from the different channels, the time-to-digital converter (TDC) implemented in Field Programmable Gate Array (FPGA) is a very useful device. The TDC implemented so far are basically tapped delay lines which provides a resolution of about 10 ps however such high resolution is necessary for some specific applications. So a low resource TDC implemented in FPGA is preferred which helps to measure the time difference between the signals.Keywords: analog-to-digital converter (ADC), resolution, DPLL, clock generation, jitte
Cohort profile: a national, population-based cohort of children born after assisted conception in the UK (1992–2009): methodology and birthweight analysis
PURPOSE: To generate a large cohort of children born after assisted reproductive technology (ART) in the UK between 1992 and 2009, their naturally conceived siblings (NCS) and matched naturally conceived population (NCP) controls and linking this with health outcome data to allow exploration of the effects of ART. The effects of fresh and frozen embryo transfer on birth weight (BW) were analysed to test the validity of the cohort. PARTICIPANTS: Children recorded on the Human Fertilisation and Embryology Authority (HFEA) register as being born after ART between 1992 and 2009, their NCS and matched NCP controls linked to Office for National Statistics birth registration dataset (HFEA-ONS cohort). This cohort was further linked to the UK Hospital Episode Statistics database to allow monitoring of the child's post-natal health outcomes up to 2015 (HFEA-ONS-HES subcohort). FINDINGS TO DATE: The HFEA-ONS cohort consisted of 75 348 children born after non-donor ART carried out in the UK between 1 April 1992 and 31 July 2009 and successfully linked to birth registration records, 14 763 NCS and 164 823 matched NCP controls. The HFEA-ONS-HES subcohort included 63 877 ART, 11 343 NCS and 127 544 matched NCP controls further linked to health outcome data. The exemplar analysis showed that children born after fresh embryo transfers were lighter (BW difference: -131 g, 95% CI: -140 to -123) and those born after frozen embryo transfers were heavier (BW difference: 35 g, 95% CI: 19 to 52) than the NCP controls. The within-sibling analyses were directionally consistent with the population control analyses, but attenuated markedly for the fresh versus natural conception (BW difference: -54 g; 95% CI: -72 to -36) and increased markedly for the frozen versus natural conception (BW difference: 152 g; 95% CI: 113 to 190) analyses. FUTURE PLANS: To use this cohort to explore the relationship between ART conception and short-term and long-term health outcomes in offspring
Switching the stereochemical outcome of 6-endo-trig cyclizations; Synthesis of 2,6-Cis-6-substituted 4-oxopipecolic acids
A base-mediated 6-endo-trig cyclization of
readily accessible enone-derived α-amino acids has been
developed for the direct synthesis of novel 2,6-cis-6-
substituted-4-oxo-L-pipecolic acids. A range of aliphatic and
aryl side chains were tolerated by this mild procedure to give
the target compounds in good overall yields. Molecular
modeling of the 6-endo-trig cyclization allowed some insight as
to how these compounds were formed, with the enolate
intermediate generated via an equilibrium process, followed by irreversible tautomerization/neutralization providing the driving force for product formation. Stereoselective reduction and deprotection of the resulting 2,6-cis-6-substituted 4-oxo-L-pipecolic acids to the corresponding 4-hydroxy-L-pipecolic acids was also performed
Adenoid cystic carcinoma of lung: An oncologic rarity treated with definitive chemo-radiation
Adenoid Cystic Carcinoma is a rare variant of adenocarcinoma originating mainly from salivary glands of the head and neck region distributed throughout the upper aerodigestive tract with a propensity for perineural invasion. Primary adenoid cystic carcinoma of lungs is exceedingly rare accounting for a mere 0.04 to 0.2 percent of all pulmonary neoplasms. The existing scant case reports about this lung malignancy mostly describe small lung lesions managed with upfront surgery followed by adjuvant radiotherapy. We hereby present this case of primary lung parenchymal pathology where the disease was treated with definitive chemo-radiation and to the best of our knowledge; this case is one of the rarest and earliest reports of upfront chemo-radiation in an inoperable primary lung parenchymal ACC. A 43-year-old woman presented with complaints of cough, severe dyspnea, right sided chest pain associated with occasional hemoptysis. Radiographic imaging of thorax showed a large mass lesion with smooth margins measuring 10.2 × 7.3 × 6.8 cm right lower lobe with invasion of adjacent vital structures. Image guided biopsy and immunohistochemical analysis confirmed the diagnosis. She was eventually treated with definitive radiotherapy with concurrent chemotherapy as she was deemed inoperable. Post therapy evaluation by imaging showed a partial response to chemo-radiation, however there was significant symptomatic relief. In view of CD 117 positivity, she has started on oral imatinib mesylate. Presently she is on follow up with a karnofsky performance status of 90%. A thorough review of literature also reveals that our case may be the largest adenoid cystic primary parenchymal pulmonary pathology ever reported
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