42,801 research outputs found
Enumerating Segmented Patterns in Compositions and Encoding by Restricted Permutations
A composition of a nonnegative integer (n) is a sequence of positive integers
whose sum is (n). A composition is palindromic if it is unchanged when its
terms are read in reverse order. We provide a generating function for the
number of occurrences of arbitrary segmented partially ordered patterns among
compositions of (n) with a prescribed number of parts. These patterns
generalize the notions of rises, drops, and levels studied in the literature.
We also obtain results enumerating parts with given sizes and locations among
compositions and palindromic compositions with a given number of parts. Our
results are motivated by "encoding by restricted permutations," a relatively
undeveloped method that provides a language for describing many combinatorial
objects. We conclude with some examples demonstrating bijections between
restricted permutations and other objects.Comment: 12 pages, 1 figur
Improved ontology for eukaryotic single-exon coding sequences in biological databases
Indexación: Scopus.Efficient extraction of knowledge from biological data requires the development of structured vocabularies to unambiguously define biological terms. This paper proposes descriptions and definitions to disambiguate the term 'single-exon gene'. Eukaryotic Single-Exon Genes (SEGs) have been defined as genes that do not have introns in their protein coding sequences. They have been studied not only to determine their origin and evolution but also because their expression has been linked to several types of human cancer and neurological/developmental disorders and many exhibit tissue-specific transcription. Unfortunately, the term 'SEGs' is rife with ambiguity, leading to biological misinterpretations. In the classic definition, no distinction is made between SEGs that harbor introns in their untranslated regions (UTRs) versus those without. This distinction is important to make because the presence of introns in UTRs affects transcriptional regulation and post-transcriptional processing of the mRNA. In addition, recent whole-transcriptome shotgun sequencing has led to the discovery of many examples of single-exon mRNAs that arise from alternative splicing of multi-exon genes, these single-exon isoforms are being confused with SEGs despite their clearly different origin. The increasing expansion of RNA-seq datasets makes it imperative to distinguish the different SEG types before annotation errors become indelibly propagated in biological databases. This paper develops a structured vocabulary for their disambiguation, allowing a major reassessment of their evolutionary trajectories, regulation, RNA processing and transport, and provides the opportunity to improve the detection of gene associations with disorders including cancers, neurological and developmental diseases. © The Author(s) 2018. Published by Oxford University Press.https://academic.oup.com/database/article/doi/10.1093/database/bay089/509943
The application of remotely sensed data to pedologic and geomorphic mapping on alluvial fan and playa surfaces in Saline Valley, California
Arid and semiarid regions yield excellent opportunities for the study of pedologic and geomorphic processes. The dominance of rock and soil exposure over vegetation not only provides the ground observer with observational possibilities but also affords good opportunities for measurement by aircraft and satellite remote sensor devices. Previous studies conducted in the area of pedologic and geomorphic mapping in arid regions with remotely sensed data have utilized information obtained in the visible to near-infrared portion of the spectrum. Thermal Infrared Multispectral Scanner (TIMS) and Thematic Mapping (TM) data collected in 1984 are being used in comjunction with maps compiled during a Bureau of Land Management (BLM) soil survey to aid in a detailed mapping of alluvial fan and playa surfaces within the valley. The results from this study may yield valuable information concerning the application of thermal data and thermal/visible data combinations to the problem of dating pedologic and geomorphic features in arid regions
Mechanization of and experience with a triplex fly-by-wire backup control system
A redundant three-axis analog control system was designed and developed to back up a digital fly-by-wire control system for an F-8C airplane. Forty-two flights, involving 58 hours of flight time, were flown by six pilots. The mechanization and operational experience with the backup control system, the problems involved in synchronizing it with the primary system, and the reliability of the system are discussed. The backup control system was dissimilar to the primary system, and it provided satisfactory handling through the flight envelope evaluated. Limited flight tests of a variety of control tasks showed that control was also satisfactory when the backup control system was controlled by a minimum-displacement (force) side stick. The operational reliability of the F-8 digital fly-by-wire control system was satisfactory, with no unintentional downmodes to the backup control system in flight. The ground and flight reliability of the system's components is discussed
Mechanization of and experience with a triplex fly-by-wire backup control system
A redundant three axis analog control system was designed and developed to back up a digital fly by wire control system for an F-8C airplane. The mechanization and operational experience with the backup control system, the problems involved in synchronizing it with the primary system, and the reliability of the system are discussed. The backup control system was dissimilar to the primary system, and it provided satisfactory handling through the flight envelope evaluated. Limited flight tests of a variety of control tasks showed that control was also satisfactory when the backup control system was controlled by a minimum displacement (force) side stick. The operational reliability of the F-8 digital fly by wire control system was satisfactory, with no unintentional downmodes to the backup control system in flight. The ground and flight reliability of the system's components is discussed
The Abduction of Europa
The refugee crisis and the ascent of right-wing populism remind Europe of its hybrid origin and the search for a solution must start from there.
Europe – you might know it – is a woman. According to Greek mythology, she was the beautiful daughter of a Phoenician king who was abducted by the mighty God Zeus. The story goes like this: Godfather Zeus falls in love with Europa. In order to deceive his jealous wife Hera, Zeus takes on the form of a white bull to approach Europa as she plays at a beach in Sidon, a city in what is today known as Lebanon.
DOI: 10.5281/zenodo.337211
Bankruptcy risk model and empirical tests
We analyze the size dependence and temporal stability of firm bankruptcy risk
in the US economy by applying Zipf scaling techniques. We focus on a single
risk factor-the debt-to-asset ratio R-in order to study the stability of the
Zipf distribution of R over time. We find that the Zipf exponent increases
during market crashes, implying that firms go bankrupt with larger values of R.
Based on the Zipf analysis, we employ Bayes's theorem and relate the
conditional probability that a bankrupt firm has a ratio R with the conditional
probability of bankruptcy for a firm with a given R value. For 2,737 bankrupt
firms, we demonstrate size dependence in assets change during the bankruptcy
proceedings. Prepetition firm assets and petition firm assets follow Zipf
distributions but with different exponents, meaning that firms with smaller
assets adjust their assets more than firms with larger assets during the
bankruptcy process. We compare bankrupt firms with nonbankrupt firms by
analyzing the assets and liabilities of two large subsets of the US economy:
2,545 Nasdaq members and 1,680 New York Stock Exchange (NYSE) members. We find
that both assets and liabilities follow a Pareto distribution. The finding is
not a trivial consequence of the Zipf scaling relationship of firm size
quantified by employees-although the market capitalization of Nasdaq stocks
follows a Pareto distribution, the same distribution does not describe NYSE
stocks. We propose a coupled Simon model that simultaneously evolves both
assets and debt with the possibility of bankruptcy, and we also consider the
possibility of firm mergers.Comment: 8 pages, 8 figure
Item-writing Rules: Collective Wisdom
In student assessment, teachers place the greatest weight on tests they have constructed themselves and have an equally great interest in the quality of those tests. To increase the validity of teacher-made tests, many item-writing rules-of-thumb are available in the literature, but few rules have been tested experimentally. In light of the paucity of empirical studies, the validity of any given guideline might best be established by relying on experts. This study analyzed twenty classroom assessment textbooks to identify a consensus list of item-writing rules. Forty rules for which there was agreement among textbook authors are presented. The rules address four different validity concerns-potentially confusing wording or ambiguous requirements, the problem of guessing, test-taking efficiency, and controlling for testwiseness
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