Application of the novint falcon haptic device as an actuator in real-time control

The two goals of this thesis are A) to develop an embedded system whose purpose is to control the Novint Falcon as a robot, and B) to develop a control experiment that demonstrates the use the Novint Falcon as a robotic actuator. The contents of this report are therefore divided into two parts. Part A deals specifically with the Novint Falcon, which is a PC input device which is "haptic" in the sense that it has a force feedback component. It is similar in configuration to the common delta robot, whose speed and accuracy has made it useful in pick-and-place operations. Along with its relatively low cost compared with other platforms, this makes it a good candidate for academic application in robot modeling and control. An embedded system is developed to interface with the multiple motors and sensors present in the Novint Falcon. Part B deals with demonstrating the use of the Novint Falcon as an actuator for a ball-on-plate control experiment. The results show that the device is a viable solution for high-speed actuation of small-scale mechanical systems

Perspectives on next steps in classification of oro-facial pain - Part 3: biomarkers of chronic oro-facial pain - from research to clinic

The purpose of this study was to review the current status of biomarkers used in oro-facial pain conditions. Specifically, we critically appraise their relative strengths and weaknesses for assessing mechanisms associated with the oro-facial pain conditions and interpret that information in the light of their current value for use in diagnosis. In the third section, we explore biomarkers through the perspective of ontological realism. We discuss ontological problems of biomarkers as currently widely conceptualised and implemented. This leads to recommendations for research practice aimed to a better understanding of the potential contribution that biomarkers might make to oro-facial pain diagnosis and thereby fulfil our goal for an expanded multidimensional framework for oro-facial pain conditions that would include a third axis

Morphological, nutritional and safety traits of bluefin tuna (Thunnus thynnus) reared in floating cages

To evaluate the influence of fattening on morphological, nutritional and safety characteristics, two lots of bluefin tuna were sampled before (November: 2 C, 4 ?) and after 5 months of fattening (April: 5 C, 5 ?). The specimens, after death, were refrigerated and analysed at different times over the period of a week for morphological and flesh physico-chemical parameters in six muscle sites. Tuna sampled in April had greater body weight (44.04 vs 36.41kg), trunk length (52.21 vs 48.22cm) and minimum and maximum circumferences (13.74 vs 12.77 and 94.90 vs 89.10cm). No differences in other linear measures or body components were found. Fattening did not influence flesh colour or total lipid content, producing small differences in its chemical composition: greater C18:0, C18:1n9 and PUFAn6 percentages; higher putrescine and histamine (0.489 vs 0.335 and 0.666 vs 0.370mg/kg) but lower spermine and spermidine (10.598 vs 17.387 and 2.420 vs 3.928mg/kg) levels. Large differences in physico-chemical parameters were found between muscle sites and a significant interaction between sampling date and muscle site indicated non homogeneous changes in chemical composition of dorsal, ventral and red muscle after fattening. Sex only influenced fat content in viscera (C 12.84 vs ? 9.84%)

Effect of orthopedic and functional orthodontic treatment in children with obstructive sleep apnea: A systematic review and meta-analysis

Orthodontic treatment is suggested in growing individuals to correct transverse maxillary deficiency and mandibular retrusion. Since, as a secondary effect, these orthodontic procedures may improve pediatric obstructive sleep apnea (OSA), this systematic review assessed their effects on apnea-hypopnea index (AHI) and oxygen saturation (SaO2). Twenty-five (25) manuscripts were included for qualitative synthesis, 19 were selected for quantitative synthesis. Five interventions were analyzed: rapid maxillary expansion (RME, 15 studies), mandibular advancement (MAA, five studies), myofunctional therapy (MT, four studies), and RME combined with MAA (one study). RME produced a significant AHI reduction and minimum SaO2 increase immediately after active treatment, at six and 12 months from baseline. A significant AHI reduction was also observed six and 12 months after the beginning of MAA treatment. MT showed positive effects, with different protocols. In this systematic review and meta-analysis of data from mainly uncontrolled studies, interceptive orthodontic treatments showed overall favorable effects on respiratory outcomes in pediatric OSA. However, due to the low to very low level of the body evidence, this treatment cannot be suggested as elective for OSA treatment. An orthodontic indication is needed to support this therapy and a careful monitoring is required to ensure positive improvement in OSA parameters

Evaluation of safety and activity of everolimus plus exemestane in metastatic breast cancer: a single institution experience.

Abstract not availabl

T-DM1 for HER2 positive advanced breast cancer:a single institution, "real-life" experience.

No abstract availabl

Draft Genome Sequence of Lactobacillus plantarum Lp90 Isolated from Wine

Contains fulltext : 155072.pdf (publisher's version ) (Open Access)Here, we describe the draft genome sequence and annotation of Lactobacillus plantarum strain Lp90, the first sequenced genome of a L. plantarum strain isolated from wine. This strain has a noticeable ropy phenotype and showed potential probiotic properties. The genome consists of 3,324,076 bp (33 contigs) and contains 3,155 protein coding genes, 34 pseudogenes, and 84 RNA genes

Generalized Courant-Snyder Theory for Charged-Particle Dynamics in General Focusing Lattices

The Courant-Snyder (CS) theory for one degree of freedom is generalized to the case of coupled transverse dynamics in general linear focusing lattices with quadrupole, skew-quadrupole, dipole, and solenoidal components, as well as torsion of the fiducial orbit and variation of beam energy. The envelope function is generalized into an envelope matrix, and the phase advance is generalized into a 4D sympletic rotation. The envelope equation, the transfer matrix, and the CS invariant of the original CS theory all have their counterparts, with remarkably similar expressions, in the generalized theory.open7