Tajik Depression and Greater Pamir Neotectonics From InSAR Rate Maps

Using E-W and vertical deformation-rate maps derived from radar interferometric time-series, we analyze the deformation field of an entire orogenic segment, that is, the Tajik depression and its adjoining mountain belts, Tian Shan, Pamir, and Hindu Kush. The data-base consists of 900+ radar scenes acquired over 2.0–4.5 years and global navigation satellite system measurements. The recent, supra-regional kinematics is visualized in an unprecedented spatio-temporal resolution. We confirm the westward collapse of the Pamir-Plateau crust, inverting the Tajik basin into a fold-thrust belt (FTB) with shortening rates decaying westward from ∼15 to 2 mm/yr. Vertical rates in the Hindu Kush likely record slab-dynamic effects, that is, the progressive break-off of the Hindu Kush slab. At least 10 mm/yr of each, uplift and westward motion occur along the western edge of the Pamir Plateau, outlining the crustal-scale ramp along which the Pamir Plateau overrides the Tajik depression. The latter shows a combination of basin-scale tectonics, halokinesis, and seasonal/weather-driven near-surface effects. Abrupt ∼6 mm/yr horizontal-rate changes occur across the kinematically linked dextral Ilyak strike-slip fault, bounding the Tajik FTB to the north, and the Babatag backthrust, the major thrust of the FTB, located far west in the belt. The sharp rate decay across the Ilyak fault indicates a locking depth of ≤1 km. The Hoja Mumin salt fountain is spreading laterally at ≤350 mm/yr. On the first-order, the modern 20–5 and fossil (since ∼12 Ma) 12–8 mm/yr shortening rates across the FTB correspond

Some properties of differentiable p-adic functions

In this paper, using the tools from the lineability theory, we distinguish certain subsets of p-adic differentiable functions. Specifically, we show that the following sets of functions are large enough to contain an infinite dimensional algebraic structure: (i) continuously differentiable but not strictly differentiable functions, (ii) strictly differentiable functions of order r but not strictly differentiable of order r + 1, (iii) strictly differentiable functions with zero derivative that are not Lipschitzian of any order α > 1, (iv) differentiable functions with unbounded derivative, and (v) continuous functions that are differentiable on a full set with respect to the Haar measure but not differentiable on its complement having cardinality the continuum.Depto. de Análisis Matemático y Matemática AplicadaFac. de Ciencias MatemáticasFALSEMinisterio de Ciencia e Innovación (MICINN)/FEDERINSFunpu

BALL - biochemical algorithms library 1.3

<p>Abstract</p> <p>Background</p> <p>The Biochemical Algorithms Library (BALL) is a comprehensive rapid application development framework for structural bioinformatics. It provides an extensive C++ class library of data structures and algorithms for molecular modeling and structural bioinformatics. Using BALL as a programming toolbox does not only allow to greatly reduce application development times but also helps in ensuring stability and correctness by avoiding the error-prone reimplementation of complex algorithms and replacing them with calls into the library that has been well-tested by a large number of developers. In the ten years since its original publication, BALL has seen a substantial increase in functionality and numerous other improvements.</p> <p>Results</p> <p>Here, we discuss BALL's current functionality and highlight the key additions and improvements: support for additional file formats, molecular edit-functionality, new molecular mechanics force fields, novel energy minimization techniques, docking algorithms, and support for cheminformatics.</p> <p>Conclusions</p> <p>BALL is available for all major operating systems, including Linux, Windows, and MacOS X. It is available free of charge under the Lesser GNU Public License (LPGL). Parts of the code are distributed under the GNU Public License (GPL). BALL is available as source code and binary packages from the project web site at <url>http://www.ball-project.org</url>. Recently, it has been accepted into the debian project; integration into further distributions is currently pursued.</p

Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence

Background: There is scepticism about health effects of dairy products in the public, which is reflected in an increasing intake of plant-based drinks, for example, from soy, rice, almond, or oat. Objective: This review aimed to assess the scientific evidence mainly from meta-analyses of observational studies and randomised controlled trials, on dairy intake and risk of obesity, type 2 diabetes, cardiovascular disease, osteoporosis, cancer, and all-cause mortality. Results: The most recent evidence suggested that intake of milk and dairy products was associated with reduced risk of childhood obesity. In adults, intake of dairy products was shown to improve body composition and facilitate weight loss during energy restriction. In addition, intake of milk and dairy products was associated with a neutral or reduced risk of type 2 diabetes and a reduced risk of cardiovascular disease, particularly stroke. Furthermore, the evidence suggested a beneficial effect of milk and dairy intake on bone mineral density but no association with risk of bone fracture. Among cancers, milk and dairy intake was inversely associated with colorectal cancer, bladder cancer, gastric cancer, and breast cancer, and not associated with risk of pancreatic cancer, ovarian cancer, or lung cancer,while the evidence for prostate cancer risk was inconsistent.Finally,consumption of milk and dairy products was not associated with all-cause mortality. Calcium-fortified plant-based drinks have been included as an alternative to dairy products in the nutrition recommendations in several countries. However, nutritionally, cow’s milk and plant-based drinks are completely different foods,and an evidence-based conclusion on the health value of the plant-based drinks requires more studies in humans. Conclusion: The totality of available scientific evidence supports that intake of milk and dairy products contribute to meet nutrient recommendations, and may protect against the most prevalent chronic diseases, whereas very few adverse effects have been reported

A922 Sequential measurement of 1 hour creatinine clearance (1-CRCL) in critically ill patients at risk of acute kidney injury (AKI)

Meeting abstrac

Upstream Supply Chain Visibility and Complexity Effect on Focal Company’s Sustainable Performance: Indian Manufacturers’ Perspective

Understanding supply chain sustainability performance is increasingly important for supply chain researchers and managers. Literature has considered supply chain sustainability and the antecedents of performance from a triple bottom line (economic, social, and environmental) perspective. However, the role of supply chain visibility and product complexity contingency in achieving sustainable supply chain performance has not been explored in depth. To address this gap, this study utilizes a contingent resource-based view theory perspective to understand the role of product complexity in shaping the relationship between upstream supply chain visibility (resources and capabilities) and the social, environmental, and economic performance dimensions. We develop and test a theoretical model using survey data gathered from 312 Indian manufacturing organizations. Our findings indicate that supply chain visibility (SCV) has significant influence on social and environmental performance under the moderation effect of product complexity. Hence, the study makes significant contribution to the extant literature by examining the impact of SCV under moderating effect of product complexity on social performance and environmental performance

Hypergroup algebras as topological algebras

Let K be a locally compact hypergroup endowed with a left Haar measure and let L1(K) be the usual Lebesgue space of K with respect to the left Haar measure. We investigate some properties of L1(K) under a locally convex topology β1. Among other things, the semireflexivity of (L1(K),β1) and of sequentiallyβ1-continuous functionals is studied. We also show that (L1(K),β1) with the convolution multiplication is always a complete semitopological algebra, whereas it is a topological algebra if and only if K is compact