Magnetoconductance oscillations in quasiballistic multimode nanowires

We calculate the conductance of quasi-one-dimensional nanowires with electronic states confined to a surface charge layer, in the presence of a uniform magnetic field. Two-terminal magnetoconductance (MC) between two leads deposited on the nanowire via tunnel barriers is dominated by density-of-states (DOS) singularities, when the leads are well apart. There is also a mesoscopic correction due to a higher-order coherent tunneling between the leads for small lead separation. The corresponding MC structure depends on the interference between electron propagation via different channels connecting the leads, which in the simplest case, for the magnetic field along the wire axis, can be crudely characterized by relative winding numbers of paths enclosing the magnetic flux. In general, the MC oscillations are aperiodic, due to the Zeeman splitting, field misalignment with the wire axis, and a finite extent of electron distribution across the wire cross section, and are affected by spin-orbit coupling. The quantum-interference MC traces contain a wealth of information about the electronic structure of multichannel wires, which would be complimentary to the DOS measurements. We propose a four-terminal configuration to enhance the relative contribution of the higher-order tunneling processes and apply our results to realistic InAs nanowires carrying several quantum channels in the surface charge-accumulation layer.Comment: 11 pages, 8 figure

Impact of DNA ligase IV on the fidelity of end joining in human cells

A DNA ligase IV (LIG4)‐null human pre‐B cell line and human cell lines with hypomorphic mutations in LIG4 are significantly impaired in the frequency and fidelity of end joining using an in vivo plasmid assay. Analysis of the null line demonstrates the existence of an error‐prone DNA ligase IV‐independent rejoining mechanism in mammalian cells. Analysis of lines with hypomorphic mutations demonstrates that residual DNA ligase IV activity, which is sufficient to promote efficient end joining, nevertheless can result in decreased fidelity of rejoining. Thus, DNA ligase IV is an important factor influencing the fidelity of end joining in vivo. The LIG4‐defective cell lines also showed impaired end joining in an in vitro assay using cell‐free extracts. Elevated degradation of the terminal nucleotide was observed in a LIG4‐defective line, and addition of the DNA ligase IV–XRCC4 complex restored end protection. End protection by DNA ligase IV was not dependent upon ligation. Finally, using purified proteins, we demonstrate that DNA ligase IV–XRCC4 is able to protect DNA ends from degradation by T7 exonuclease. Thus, the ability of DNA ligase IV–XRCC4 to protect DNA ends may contribute to the ability of DNA ligase IV to promote accurate rejoining in vivo

Atomic layer deposition of ZnS nanotubes

We report on growth of high-aspect-ratio ($\gtrsim300$) zinc sulfide nanotubes with variable, precisely tunable, wall thicknesses and tube diameters into highly ordered pores of anodic alumina templates by atomic layer deposition (ALD) at temperatures as low as 75 $^{\circ}$C. Various characterization techniques are employed to gain information on the composition, morphology, and crystal structure of the synthesized samples. Besides practical applications, the ALD-grown tubes could be envisaged as model systems for the study of a certain class of size-dependent quantum and classical phenomena.Comment: 1 LaTeX source file, 8 eps figures, and the manuscript in PDF forma

Semiconductor Nanowire Laser and Nanowire Waveguide Electro-optic Modulators

Electric field modulation of visible and ultraviolet nanoscale lasers consisting of single CdS or GaN nanowires has been achieved using integrated, microfabricated electrodes. Modulation of laser emission intensity is achieved with no detectable change in the laser wavelength. The devices can also be operated below the lasing threshold to modulate the intensity of light propagating within the nanowire waveguide. Studies of the electric field dependence in devices of varied geometry indicate that modulation is due to an electroabsorption mechanism. These findings expand opportunities for multicolor, nanowire-based photonic devices and circuits

Growth and Transport Properties of Complementary Germanium Nanowire Field Effect Transistors

n- and p-type Ge nanowires were synthesized by a multistep process in which axial elongation, via vapor–liquid–solid (VLS) growth, and doping were accomplished in separate chemical vapor deposition steps. Intrinsic, single-crystal, Ge nanowires prepared by Au nanocluster-mediated VLS growth were surface-doped in situ using diborane or phosphine, and then radial growth of an epitaxial Ge shell was used to cap the dopant layer. Field-effect transistors prepared from these Ge nanowires exhibited on currents and transconductances up to 850 µA/µm and 4.9 µA/V, respectively, with device yields of \u3e85%

Progress Monitoring in Inclusive Preschools: Using Children's School Success+ Curriculum Framework

Progress monitoring in inclusive preschool classrooms should describe all children's progress towards general curriculum outcomes and individual children's unique outcomes or IEP goals. This research study used the Children's School Success+ Curriculum Framework (CSS+ Curriculum Framework) and progress monitoring process to assess the outcomes of 73 children on these dimensions. Children's progress monitoring data were analyzed within groupings based on instructional need level (i.e., low, medium, or high) in academic content and social domains. Progress monitoring findings for both the academic and social support level of need groups showed significant progress pre- to posttest on most academic outcomes, but some variation with less consistent gains within the social emotional domain. Goal attainment scaling data demonstrated children's gains toward achieving their social goals (individualized education program [IEP] or specific learning goals) were at the expected level between 50% and 71% of the time. Academic-focused goal attainment was at or above the expected level of between 54% and 76% of the time, based on the learning grouping. Teacher implementation of CSS+ Curriculum Framework appeared to impact change in classroom and instructional practices pre-post intervention

Self-directed growth of AlGaAs core-shell nanowires for visible light applications

Al(0.37)Ga(0.63)As nanowires (NWs) were grown in a molecular beam epitaxy system on GaAs(111)B substrates. Micro-photoluminescence measurements and energy dispersive X-ray spectroscopy indicated a core-shell structure and Al composition gradient along the NW axis, producing a potential minimum for carrier confinement. The core-shell structure formed during the growth as a consequence of the different Al and Ga adatom diffusion lengths.Comment: 20 pages, 7 figure

Acquisition of Adaptation Knowledge for Breast Cancer Treatment Decision Support

Colloque avec actes et comité de lecture. internationale.International audienceThe elaboration of a treatment in cancerology depends on the particular practice of decision protocols. These protocols are often adapted rather than used straightforwardly. This paper deals with the acquisition of the knowledge exploited during protocol adaptations. It shows that this knowledge acquisition process can be based on similarity paths, that are used for representing the matchings between decision problems (e.g., source and target problems within a case-based reasoning process)

Inquérito soroepidemiológico para pesquisa de infecções por arbovírus em moradores de reserva ecológica

OBJETIVO: Inquéritos sorológicos têm evidenciado ampla circulação de arbovírus causadores de doença humana na Região do Vale do Ribeira, São Paulo, Brasil. Com o propósito de estabelecer a prevalência de infecções por esses agentes em reserva ecológica, localizada naquela área, pesquisou-se a presença de anticorpos, bem como suas possíveis associações com características individuais e familiares dos investigados. MÉTODOS: Pesquisaram-se anticorpos para os antígenos dos vírus Rocio (ROC), Ilhéus (ILH), encefalite de St. Louis (SLE), encefalites eqüinas do leste (EEE), oeste (WEE) e venezuelana (VEE), em 182 pessoas pertencentes a 58 famílias residentes na Estação Ecológica de Juréia-Itatins, utilizando-se testes de inibição de hemaglutinação e neutralização com redução de placas. Usou-se Mac-Elisa para pesquisar anticorpos IgM para os vírus ROC, ILH e EEE. RESULTADOS: Foi observada a presença de anticorpos para todos os arbovírus testados, com exceção do vírus WEE. A prevalência total de anticorpos foi 26,9% (21,4% para alfavírus e 12,6% para flavivírus). Não foram encontrados anticorpos IgM. Entre as várias características pesquisadas dos indivíduos e de suas famílias, a idade, a ocupação, a naturalidade e o hábito de entrar na mata mostraram-se estatisticamente associados a infecções por arbovírus (pOBJECTIVE: Serological inquires conducted in the Ribeira Valley, S. Paulo State, Brazil, showed an intense circulation of pathogenic arboviruses in the region. The goal was to verify the prevalence of arboviral infections in people living at the local ecological, and its potential association with these population' individual and familiar characteristics. METHODS: The study was carried out among 182 persons of 58 families to identify the presence of antibodies to the following viruses: Rocio (ROC), Ilheus (ILH), Eastern equine encephalitis virus (EEE), Western equine encephalitis virus (WEE), Venezuelan equine encephalitis virus (VEE) and St. Louis encephalitis virus (SLE). Inhibition hemagglutination test and plaque reduction neutralization test were the laboratory assays of choice. MAC-ELISA was used to identify IgM antibodies to ROC, ILH and EEE viruses. RESULTS: The prevalence of antibodies was 26.9% (21.4% to alphavirus and 12.6% to flavivirus). There were no antibodies to WEE virus. IgM antibodies were not observed suggesting no recent infection in study population. Among the characteristics investigated, age, occupation, place of birth and the habit of going into the forest were shown to be statistically associated with arboviral infection (