Effect of Exercise-Induced Reductions in Blood Volume on Cardiac Output and Oxygen Transport Capacity

We wanted to demonstrate the relationship between blood volume, cardiac size, cardiac output and maximum oxygen uptake ([Formula: see text] O(2max)) and to quantify blood volume shifts during exercise and their impact on oxygen transport. Twenty-four healthy, non-smoking, heterogeneously trained male participants (27 ± 4.6 years) performed incremental cycle ergometer tests to determine [Formula: see text] O(2max) and changes in blood volume and cardiac output. Cardiac output was determined by an inert gas rebreathing procedure. Heart dimensions were determined by 3D echocardiography. Blood volume and hemoglobin mass were determined by using the optimized CO-rebreathing method. The [Formula: see text] O(2max) ranged between 47.5 and 74.1 mL⋅kg(–1)⋅min(–1). Heart volume ranged between 7.7 and 17.9 mL⋅kg(–1) and maximum cardiac output ranged between 252 and 434 mL⋅kg(–1)⋅min(–1). The mean blood volume decreased by 8% (567 ± 187 mL, p = 0.001) until maximum exercise, leading to an increase in [Hb] by 1.3 ± 0.4 g⋅dL(–1) while peripheral oxygen saturation decreased by 6.1 ± 2.4%. There were close correlations between resting blood volume and heart volume (r = 0.73, p = 0.002), maximum blood volume and maximum cardiac output (r = 0.68, p = 0.001), and maximum cardiac output and [Formula: see text] O(2max) (r = 0.76, p < 0.001). An increase in maximum blood volume by 1,000 mL was associated with an increase in maximum stroke volume by 25 mL and in maximum cardiac output by 3.5 L⋅min(–1). In conclusion, blood volume markedly decreased until maximal exhaustion, potentially affecting the stroke volume response during exercise. Simultaneously, hemoconcentrations maintained the arterial oxygen content and compensated for the potential loss in maximum cardiac output. Therefore, a large blood volume at rest is an important factor for achieving a high cardiac output during exercise and blood volume shifts compensate for the decrease in peripheral oxygen saturation, thereby maintaining a high arteriovenous oxygen difference

Spectroscopic Observations of Twenty-one Faint Cataclysmic Variables Candidates

We provide the first minimum light spectroscopic observations for 21 previously known or suspected faint cataclysmic variable candidates. The sources were selected from the Downes et al. (2001) living edition catalog and the identified candidates have minimum light magnitudes of V~18-22. We confirm 15 of the candidates to be cataclysmic variables.Comment: 10 pages, 4 figures, accepted by A&

Radial Velocity Studies of Close Binary Stars.IV

Radial-velocity measurements and sine-curve fits to the orbital velocity variations are presented for the fourth set of ten close binary systems: 44 Boo, FI Boo, V2150 Cyg, V899 Her, EX Leo, VZ Lib, SW Lyn, V2377 Oph, Anon Psc (GSC 8-324), HT Vir. All systems are double-lined spectroscopic binaries with only two of them not being contact systems (SW Lyn and GSC 8-324) and with five (FI Boo, V2150 Cyg, V899 Her, EX Leo, V2377 Oph) being the recent photometric discoveries of the Hipparcos satellite project. Five of the binaries are triple-lined systems (44 Boo, V899 Her, VZ Lib, SW Lyn, HT Vir). Three (or possibly four) companions in the triple-lined systems show radial-velocity changes during the span of our observations suggesting that these are in fact quadruple systems. Several of the studied systems are prime candidates for combined light and radial-velocity synthesis solutions.Comment: aastex5.0, 5 figures in PS; submitted to Astron.

Variable stars in the Open Cluster M11 (NGC 6705)

V-band time-series CCD photometric observations of the intermediate-age open cluster M11 were performed to search for variable stars. Using these time-series data, we carefully examined light variations of all stars in the observing field. A total of 82 variable stars were discovered, of which 39 stars had been detected recently by Hargis et al. (2005). On the basis of observational properties such as variable period, light curve shape, and position on a color-magnitude diagram, we classified their variable types as 11 delta Scuti-type pulsating stars, 2 gamma Doradus-type pulsating stars, 40 W UMa-type contact eclipsing binaries, 13 Algol-type detached eclipsing binaries, and 16 eclipsing binaries with long period. Cluster membership for each variable star was deduced from the previous proper motion results (McNamara et al. 1977) and position on the color-magnitude diagram. Many pulsating stars and eclipsing binaries in the region of M11 are probable members of the cluster.Comment: 23 pages, 9 figures, 3 tables, and accepted for publication in PAS

Prospectus, March 16, 1992

https://spark.parkland.edu/prospectus_1992/1007/thumbnail.jp

Mid - infrared interferometry of massive young stellar objects II Evidence for a circumstellar disk surrounding the Kleinmann - Wright object

The formation scenario for massive stars is still under discussion. To further constrain current theories, it is vital to spatially resolve the structures from which material accretes onto massive young stellar objects (MYSOs). Due to the small angular extent of MYSOs, one needs to overcome the limitations of conventional thermal infrared imaging, regarding spatial resolution, in order to get observational access to the inner structure of these objects.We employed mid - infrared interferometry, using the MIDI instrument on the ESO /VLTI, to investigate the Kleinmann - Wright Object, a massive young stellar object previously identified as a Herbig Be star precursor. Dispersed visibility curves in the N- band (8 - 13 {\mu}m) have been obtained at 5 interferometric baselines. We show that the mid - infrared emission region is resolved. A qualitative analysis of the data indicates a non - rotationally symmetric structure, e.g. the projection of an inclined disk. We employed extensive radiative transfer simulations based on spectral energy distribution fitting. Since SED - only fitting usually yields degenerate results, we first employed a statistical analysis of the parameters provided by the radiative transfer models. In addition, we compared the ten best - fitting self - consistent models to the interferometric observations. Our analysis of the Kleinmann - Wright Object suggests the existence of a circumstellar disk of 0.1M\odot at an intermediate inclination of 76\circ, while an additional dusty envelope is not necessary for fitting the data. Furthermore, we demonstrate that the combination of IR interferometry with radiative transfer simulations has the potential to resolve ambiguities arising from the analysis of spectral energy distributions alone.Comment: 12 pages, 22 figures accepted for publication in A&

The collateral caval shunt as an alternative to classical shunt procedures in patients with recurrent duodenal varices and extrahepatic portal vein thrombosis

Upper gastrointestinal bleeding episodes from variceal structures are severe complications in patients with portal hypertension. Endoscopic sclerotherapy and variceal ligation are the treatment options preferred for upper variceal bleeding owing to extrahepatic portal hypertension due to portal vein thrombosis (PVT). Recurrent duodenal variceal bleeding in non-cirrhotic patients with diffuse porto-splenic vein thrombosis and subsequent portal cavernous transformation represent a clinical challenge if classic shunt surgery is not possible or suitable. In this study, we represent a case of recurrent bleeding of duodenal varices in a non-cirrhotic patient with cavernous transformation of the portal vein that was successfully treated with a collateral caval shunt operation