The ESO Spectroscopic facility

We present the concept of a novel facility dedicated to massively-multiplexed spectroscopy. The telescope has a very wide field Cassegrain focus optimised for fibre feeding. With a Field of View (FoV) of 2.5 degrees diameter and a 11.4m pupil, it will be the largest etendue telescope. The large focal plane can easily host up to 16.000 fibres. In addition, a gravity invariant focus for the central 10 arc-minutes is available to host a giant integral field unit (IFU). The 3 lenses corrector includes an ADC, and has good performance in the 360-1300 nm wavelength range. The top level science requirements were developed by a dedicated ESO working group, and one of the primary cases is high resolution spectroscopy of GAIA stars and, in general, how our Galaxy formed and evolves. The facility will therefore be equipped with both, high and low resolution spectrographs. We stress the importance of developing the telescope and instrument designs simultaneously. The most relevant R\&D aspect is also briefly discussed.Comment: 6 pages 4 figures , presented at IAU Symposium 334 "rediscovering our galaxy

Fractional-Spin Integrals of Motion for the Boundary Sine-Gordon Model at the Free Fermion Point

We construct integrals of motion (IM) for the sine-Gordon model with boundary at the free Fermion point which correctly determine the boundary S matrix. The algebra of these IM (``boundary quantum group'' at q=1) is a one-parameter family of infinite-dimensional subalgebras of twisted affine sl(2). We also propose the structure of the fractional-spin IM away from the free Fermion point.Comment: 19 pages, LaTeX, no figure

Using the UN Human Rights System to Advocate for Access to Palliative Care and Pain Relief

This toolkit is a resource for organizations that want to advocate for increased access to palliative care and pain relief as a human right within the United Nations human rights system. The toolkit introduces the UN human rights system and offers step-by-step advice and resources on how to navigate it, including various treaty bodies and the UN Human Rights Council. It also discusses how to advocate for palliative care and access to pain relief in regional human rights systems

A Few Considerations on Structural and Logical Composition in Specification Theories

Over the last 20 years a large number of automata-based specification theories have been proposed for modeling of discrete,real-time and probabilistic systems. We have observed a lot of shared algebraic structure between these formalisms. In this short abstract, we collect results of our work in progress on describing and systematizing the algebraic assumptions in specification theories.Comment: In Proceedings FIT 2010, arXiv:1101.426

Atrioventricular canal defect and genetic syndromes: the unifying role of sonic hedgehog

The atrioventricular canal defect (AVCD) is a congenital heart defect (CHD) frequently associated with extracardiac anomalies (75%). Previous observations from a personal series of patients with AVCD and "polydactyly syndromes" showed that the distinct morphology and combination of AVCD features in some of these syndromes is reminiscent of the cardiac phenotype found in heterotaxy, a malformation complex previously associated with functional cilia abnormalities and aberrant Hedgehog (Hh) signaling. Hh signaling coordinates multiple aspects of left-right lateralization and cardiovascular growth. Being active at the venous pole the secondary heart field (SHF) is essential for normal development of dorsal mesenchymal protrusion and AVCD formation and septation. Experimental data show that perturbations of different components of the Hh pathway can lead to developmental errors presenting with partially overlapping manifestations and AVCD as a common denominator. We review the potential role of Hh signaling in the pathogenesis of AVCD in different genetic disorders. AVCD can be viewed as part of a "developmental field," according to the concept that malformations can be due to defects in signal transduction cascades or pathways, as morphogenetic units which may be altered by Mendelian mutations, aneuploidies, and environmental causes

Ballistic effectiveness of Zr-containing composite solid propellants as a function of binder nature and mass fraction

This paper considers the effects of binder mass fraction on the properties of energetic formulations based on zirconium and zirconium hydride. These ingredients, replacing aluminum in solid rocket motors with low vehicle performance coefficient, may increase the propellant ballistic effectiveness, thanks to the resulting higher density and notwithstanding their lower specific impulse. The propellant ballistic effectiveness is estimated via the vehicle velocity achieved using the propellant under analysis in a real vehicle. For each specific mission, the binder content can be varied to provide the optimal relationship between energetic and physical-mechanical properties, that is, one may sacrifice energy in favor of rheological and physicomechanical properties (increasing binder mass fraction), or vice versa

A space-time generator for rainfall nowcasting: the PRAISEST model

International audienceThe paper introduces a new stochastic technique for forecasting rainfall in space-time domain: the PRAISEST Model (Prediction of Rainfall Amount Inside Storm Events: Space and Time). The model is based on the assumption that the rainfall height H accumulated on an interval ?t between the instants i?t and (i+1)?t and on a spatial cell of size ?x?y is correlated either with a variable Z, representing antecedent precipitation at the same point, either with a variable W, representing simultaneous rainfall at neighbour cells. The mathematical background is given by a joined probability density fH,W,Z (h,w,z) in which the variables have a mixed nature, that is a finite probability for null value and infinitesimal probabilities for the positive values. As study area, the Calabria region, in Southern Italy, has been selected. The region has been discretised by 10 km×10 km cell grid, according to the raingauge network density in this area. Storm events belonging to 1990?2004 period were analyzed to test performances of the PRAISEST model

Rainfall nowcasting by at site stochastic model P.R.A.I.S.E.

The paper introduces a stochastic model to forecast rainfall heights at site: the P.R.A.I.S.E. model (Prediction of Rainfall Amount Inside Storm Events). PRAISE is based on the assumption that the rainfall height <I>H_i</I>+1 accumulated on an interval &Delta;<I>t</I> between the instants <I>i&Delta;t</I> and <I>(i+1&Delta;t</I> is correlated with a variable <I>Z_i^(&nu;)</I>, representing antecedent precipitation. The mathematical background is given by a joined probability density <I>f_{H_i+1}, Z_i^(&nu;)(h_i+1 ,z_i^(&nu;)</I>) in which the variables have a mixed nature, that is a finite probability in correspondence to the null value and infinitesimal probabilities in correspondence to the positive values. As study area, the Calabria region, in Southern Italy, was selected, to test performances of the PRAISE model