784 research outputs found
Near-field radiation patterns for an Ultra-Wide-Band antenna
We present a three-dimensional time dependent model for simulating the electromagnetic radiation field patterns generated by Ultra-Wide-Band (UWB) antennas. UWB antennas are pulsed mode radiators used to communicate information at high bit rates over short distances. This affects the spatial characteristics of the field patterns assumed to be generated when a Continuous Wave (CW) model is used and this paper investigates the differences between the near-field intensity patterns generated when a pulse and CW mode is used. The purpose of this is to develop a numerical simulation that provides information on the three-dimensional electromagnetic field subject to a known (integrated) antenna geometry. The context of the approach considered is the design of integrated antennas that extend the performance of UWB systems in terms of range (in the near-field) subject to emission standards
“Patriotism Is Not Enough”: Edith Cavell’s Life and Death in Anglo-American Context
In October 1915, British nurse Edith Cavell was killed by the Germans for aiding in the illegal liberation of Allied soldiers. In the wake of her death, the British government created a propaganda firestorm to garner both domestic and foreign support for the war. In particular, the propaganda featuring Cavell was highly gendered and over the course of multiple generations has generated a diverse, and often polarized series of social and political responses in both Britain and the United States. Through the examination of government documents, newspapers, and popular culture, such as film and children’s novels, this thesis examines the Anglo-American reaction to the Cavell case. Furthermore, it argues that Cavell’s story served as an instrument through which to express varying gender tensions on both sides of the Atlantic for over a century
Persistence and variation in microstructural design during the evolution of spider silk
The extraordinary mechanical performance of spider dragline silk is explained by its highly ordered microstructure and results from the sequences of its constituent proteins. This optimized microstructural organization simultaneously achieves high tensile strength and strain at breaking by taking advantage of weak molecular interactions. However, elucidating how the original design evolved over the 400 million year history of spider silk, and identifying the basic relationships between microstructural details and performance have proven difficult tasks. Here we show that the analysis of maximum supercontracted single spider silk fibers using X ray diffraction shows a complex picture of silk evolution where some key microstructural features are conserved phylogenetically while others show substantial variation even among closely related species. This new understanding helps elucidate which microstructural features need to be copied in order to produce the next generation of biomimetic silk fibers
Outcome of ATP-based tumor chemosensitivity assay directed chemotherapy in heavily pre-treated recurrent ovarian carcinoma
BACKGROUND: We wished to evaluate the clinical response following ATP-Tumor Chemosensitivity Assay (ATP-TCA) directed salvage chemotherapy in a series of UK patients with advanced ovarian cancer. The results are compared with that of a similar assay used in a different country in terms of evaluability and clinical endpoints. METHODS: From November 1998 to November 2001, 46 patients with pre-treated, advanced ovarian cancer were given a total of 56 courses of chemotherapy based on in-vitro ATP-TCA responses obtained from fresh tumor samples or ascites. Forty-four patients were evaluable for results. Of these, 18 patients had clinically platinum resistant disease (relapse < 6 months after first course of chemotherapy). There was evidence of cisplatin resistance in 31 patients from their first ATP-TCA. Response to treatment was assessed by radiology, clinical assessment and tumor marker level (CA 125). RESULTS: The overall response rate was 59% (33/56) per course of chemotherapy, including 12 complete responses, 21 partial responses, 6 with stable disease, and 15 with progressive disease. Two patients were not evaluable for response having received just one cycle of chemotherapy: if these were excluded the response rate is 61%. Fifteen patients are still alive. Median progression free survival (PFS) was 6.6 months per course of chemotherapy; median overall survival (OAS) for each patient following the start of TCA-directed therapy was 10.4 months (95% confidence interval 7.9-12.8 months). CONCLUSION: The results show similar response rates to previous studies using ATP-TCA directed therapy in recurrent ovarian cancer. The assay shows high evaluability and this study adds weight to the reproducibility of results from different centre
The Role of Muslim Devotional Practices in the Reversal of Language Shift
Fishman’s 1991 scale for evaluating language vitality proposes a stage in language shift
where exclusively the older generation takes part in ‘rituals’, ‘concerts’ and ‘songfests’ in
the minority language. Once this generation dies away, according to the scale, these cultural
practices disappear with them. Within certain Muslim youth communities in the UK counter
examples exist where the younger generation leads the way in reviving, performing and
extending the repertoire of this religio-cultural heritage. Although this emerging expanded
repertoire of song and poetry is clearly multilingual in nature, recitation and performance of
the community heritage languages, Urdu and Punjabi, feature strongly. What remains to
discover is whether such increasing familiarity with poetic language and form can impact
positively on reversing the language shift these communities are experiencing in their third
and fourth generations. Although there is evidence (Ostler & Lintinger 2015) that singing and
reciting in other minority language settings, secular and religious, are not infrequent pursuits
of youth, it is argued in this article that an accompanying religious revival provides an
important extra, galvanising, boost to the process of possible reversing language shift. It is
suggested that available scales for evaluating language vitality are inadequate in the face of
complex diasporic minority language settings
Near-field radiation patterns for an Ultra-Wide-Band antenna
We present a three-dimensional time dependent model for simulating the electromagnetic radiation field patterns generated by Ultra-Wide-Band (UWB) antennas. UWB antennas are pulsed mode radiators used to communicate information at high bit rates over short distances. This affects the spatial characteristics of the field patterns assumed to be generated when a Continuous Wave (CW) model is used and this paper investigates the differences between the near-field intensity patterns generated when a pulse and CW mode is used. The purpose of this is to develop a numerical simulation that provides information on the three-dimensional electromagnetic field subject to a known (integrated) antenna geometry. The context of the approach considered is the design of integrated antennas that extend the performance of UWB systems in terms of range (in the near-field) subject to emission standards.Ye
Using behavior-analytic implicit tests to assess sexual interests among normal and sex-offender populations
The development of implicit tests for measuring biases and behavioral predispositions is a recent development within psychology. While such tests are usually researched within a social-cognitive paradigm, behavioral researchers have also begun to view these tests as potential tests of conditioning histories, including in the sexual domain.
The objective of this paper is to illustrate the utility of a behavioral approach to implicit testing and means by which implicit tests can be built to the standards of behavioral psychologists.
Research findings illustrating the short history of implicit testing within the experimental analysis of behavior are reviewed. Relevant parallel and overlapping research findings from the field of social cognition and on the Implicit Association Test are also outlined.
New preliminary data obtained with both normal and sex offender populations are described in order to illustrate how behavior-analytically conceived implicit tests may have potential as investigative tools for assessing histories of sexual arousal conditioning and derived stimulus associations.
It is concluded that popular implicit tests are likely sensitive to conditioned and derived stimulus associations in the history of the test-taker rather than 'unconscious cognitions', per se
Rationale and study design of a cross sectional study documenting the prevalence of Heart Failure amongst the minority ethnic communities in the UK: the E-ECHOES Study (Ethnic - Echocardiographic Heart of England Screening Study)
Background: Heart failure is an important cause of cardiovascular morbidity and mortality. Studies to date have not established the prevalence heart failure amongst the minority ethnic community in the UK. The aim of the E-ECHOES (Ethnic - Echocardiographic Heart of England Screening Study) is to establish, for the first time, the community prevalence and severity of left ventricular systolic dysfunction (LVSD) and heart failure amongst the South Asian and Black African-Caribbean ethnic groups in the UK.Methods/Design: This is a community based cross-sectional population survey of a sample of South Asian (i.e. those originating from India, Pakistan, Bangladesh) and Black African-Caribbean male and female subjects aged 45 years and over. Data collection undertaken using a standardised protocol comprising a questionnaire incorporating targeted clinical history taking, physical examination, and investigations with resting electrocardiography and echocardiography; and blood sampling with consent. This is the largest study on heart failure amongst these ethnic groups. Full data collection started in September 2006 and will be completed by August 2009.Discussion: The E-ECHOES study will enable the planning and delivery of clinically and cost-effective treatment of this common and debilitating condition within these communities. In addition it will increase knowledge of the aetiology and management of heart failure within minority ethnic communities
The effect of prior walking on coronary heart disease risk markers in South Asian and European men.
Purpose: Heart disease risk is elevated in South Asians possibly due to impaired postprandial metabolism. Running has been shown to induce greater reductions in postprandial lipaemia in South Asian than European men but the effect of walking in South Asians is unknown. Methods: Fifteen South Asian and 14 White European men aged 19-30 years completed two, 2-d trials in a randomised crossover design. On day 1, participants rested (control) or walked for 60 min at approximately 50% maximum oxygen uptake (exercise). On day 2, participants rested and consumed two high fat meals over a 9h period during which 14 venous blood samples were collected. Results: South Asians exhibited higher postprandial triacylglycerol (geometric mean (95% confidence interval) 2.29(1.82 to 2.89) vs. 1.54(1.21 to 1.96) mmol·L-1·hr-1), glucose (5.49(5.21 to 5.79) vs. 5.05(4.78 to 5.33) mmol·L-1·hr-1), insulin (32.9(25.7 to 42.1) vs. 18.3(14.2 to 23.7) µU·mL-1·hr-1) and interleukin-6 (2.44(1.61 to 3.67) vs. 1.04(0.68 to 1.59) pg·mL-1·hr-1) than Europeans (all ES ≥ 0.72, P≤0.03). Between-group differences in triacylglycerol, glucose and insulin were not significant after controlling for age and percentage body fat. Walking reduced postprandial triacylglycerol (1.79(1.52 to 2.12) vs. 1.97(1.67 to 2.33) mmol·L-1·hr-1) and insulin (21.0(17.0 to 26.0) vs. 28.7(23.2 to 35.4) µU·mL-1·hr-1) (all ES ≥ 0.23. P≤0.01), but group differences were not significant. Conclusions: Healthy South Asians exhibited impaired postprandial metabolism compared with White Europeans, but these differences were diminished after controlling for potential confounders. The small-moderate reduction in postprandial triacylglycerol and insulin after brisk walking was not different between the ethnicities
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