344 research outputs found
High-yield parallel fabrication of quantum-dot monolayer single-electron devices displaying Coulomb staircase, contacted by graphene.
It is challenging for conventional top-down lithography to fabricate reproducible devices very close to atomic dimensions, whereas identical molecules and very similar nanoparticles can be made bottom-up in large quantities, and can be self-assembled on surfaces. The challenge is to fabricate electrical contacts to many such small objects at the same time, so that nanocrystals and molecules can be incorporated into conventional integrated circuits. Here, we report a scalable method for contacting a self-assembled monolayer of nanoparticles with a single layer of graphene. This produces single-electron effects, in the form of a Coulomb staircase, with a yield of 87 ± 13% in device areas ranging from 2 to 16 μm2, containing up to 650,000 nanoparticles. Our technique offers scalable assembly of ultra-high densities of functional particles or molecules that could be used in electronic integrated circuits, as memories, switches, sensors or thermoelectric generators
Hemorrhage rate after coblation tonsillectomy: a meta-analysis of published trials
After the surgical procedure of tonsillectomy, hemorrhage ranks among its serious postoperative complications. In this systematic review, we analyze hemorrhage following tonsillectomies performed using the coblation technique. 24 prospective, randomized, and controlled studies were included in the meta-analysis. Data of 796 patients who had undergone coblation tonsillectomy were analyzed. Hemorrhages occurred in 33 patients: 2 classified as primary and 26 as secondary hemorrhages. 5 could not be classified into either group. Overall, the total hemorrhage rate for the coblation procedure was 4.1% with a 95% confidence interval from 2.8 to 5.5%. The overall hemorrhage rate of 4.1% found in this meta-analysis shows that coblation is a safe and effective technique for tonsillectomies with a secondary bleeding rate similar to what is reported for comparable techniques such as bipolar diathermia
Shaping black holes with free fields
Starting from a metric Ansatz permitting a weak version of Birkhoff's theorem
we find static black hole solutions including matter in the form of free scalar
and p-form fields, with and without a cosmological constant \Lambda. Single
p-form matter fields permit multiple possibilities, including dyonic solutions,
self-dual instantons and metrics with Einstein-Kaelher horizons. The inclusion
of multiple p-forms on the other hand, arranged in a homogeneous fashion with
respect to the horizon geometry, permits the construction of higher dimensional
dyonic p-form black holes and four dimensional axionic black holes with flat
horizons, when \Lambda<0. It is found that axionic fields regularize black hole
solutions in the sense, for example, of permitting regular -- rather than
singular -- small mass Reissner-Nordstrom type black holes. Their cosmic string
and Vaidya versions are also obtained.Comment: 38 pages. v2: minor changes, published versio
Magnetic Coupling in the Quiet Solar Atmosphere
Three kinds of magnetic couplings in the quiet solar atmosphere are
highlighted and discussed, all fundamentally connected to the Lorentz force.
First the coupling of the convecting and overshooting fluid in the surface
layers of the Sun with the magnetic field. Here, the plasma motion provides the
dominant force, which shapes the magnetic field and drives the surface dynamo.
Progress in the understanding of the horizontal magnetic field is summarized
and discussed. Second, the coupling between acoustic waves and the magnetic
field, in particular the phenomenon of wave conversion and wave refraction. It
is described how measurements of wave travel times in the atmosphere can
provide information about the topography of the wave conversion zone, i.e., the
surface of equal Alfv\'en and sound speed. In quiet regions, this surface
separates a highly dynamic magnetic field with fast moving magnetosonic waves
and shocks around and above it from the more slowly evolving field of high-beta
plasma below it. Third, the magnetic field also couples to the radiation field,
which leads to radiative flux channeling and increased anisotropy in the
radiation field. It is shown how faculae can be understood in terms of this
effect. The article starts with an introduction to the magnetic field of the
quiet Sun in the light of new results from the Hinode space observatory and
with a brief survey of measurements of the turbulent magnetic field with the
help of the Hanle effect.Comment: To appear in "Magnetic Coupling between the Interior and the
Atmosphere of the Sun", eds. S.S. Hasan and R.J. Rutten, Astrophysics and
Space Science Proceedings, Springer-Verlag, Heidelberg, Berlin, 200
Rapid phenotyping of crop root systems in undisturbed field soils using X-ray computed tomography
Role of cellular senescence and NOX4-mediated oxidative stress in systemic sclerosis pathogenesis.
Systemic sclerosis (SSc) is a systemic autoimmune disease characterized by progressive fibrosis of skin and numerous internal organs and a severe fibroproliferative vasculopathy resulting frequently in severe disability and high mortality. Although the etiology of SSc is unknown and the detailed mechanisms responsible for the fibrotic process have not been fully elucidated, one important observation from a large US population study was the demonstration of a late onset of SSc with a peak incidence between 45 and 54 years of age in African-American females and between 65 and 74 years of age in white females. Although it is not appropriate to consider SSc as a disease of aging, the possibility that senescence changes in the cellular elements involved in its pathogenesis may play a role has not been thoroughly examined. The process of cellular senescence is extremely complex, and the mechanisms, molecular events, and signaling pathways involved have not been fully elucidated; however, there is strong evidence to support the concept that oxidative stress caused by the excessive generation of reactive oxygen species may be one important mechanism involved. On the other hand, numerous studies have implicated oxidative stress in SSc pathogenesis, thus, suggesting a plausible mechanism in which excessive oxidative stress induces cellular senescence and that the molecular events associated with this complex process play an important role in the fibrotic and fibroproliferative vasculopathy characteristic of SSc. Here, recent studies examining the role of cellular senescence and of oxidative stress in SSc pathogenesis will be reviewed
Asteroseismology and Interferometry
Asteroseismology provides us with a unique opportunity to improve our
understanding of stellar structure and evolution. Recent developments,
including the first systematic studies of solar-like pulsators, have boosted
the impact of this field of research within Astrophysics and have led to a
significant increase in the size of the research community. In the present
paper we start by reviewing the basic observational and theoretical properties
of classical and solar-like pulsators and present results from some of the most
recent and outstanding studies of these stars. We centre our review on those
classes of pulsators for which interferometric studies are expected to provide
a significant input. We discuss current limitations to asteroseismic studies,
including difficulties in mode identification and in the accurate determination
of global parameters of pulsating stars, and, after a brief review of those
aspects of interferometry that are most relevant in this context, anticipate
how interferometric observations may contribute to overcome these limitations.
Moreover, we present results of recent pilot studies of pulsating stars
involving both asteroseismic and interferometric constraints and look into the
future, summarizing ongoing efforts concerning the development of future
instruments and satellite missions which are expected to have an impact in this
field of research.Comment: Version as published in The Astronomy and Astrophysics Review, Volume
14, Issue 3-4, pp. 217-36
The quest for the solar g modes
Solar gravity modes (or g modes) -- oscillations of the solar interior for
which buoyancy acts as the restoring force -- have the potential to provide
unprecedented inference on the structure and dynamics of the solar core,
inference that is not possible with the well observed acoustic modes (or p
modes). The high amplitude of the g-mode eigenfunctions in the core and the
evanesence of the modes in the convection zone make the modes particularly
sensitive to the physical and dynamical conditions in the core. Owing to the
existence of the convection zone, the g modes have very low amplitudes at
photospheric levels, which makes the modes extremely hard to detect. In this
paper, we review the current state of play regarding attempts to detect g
modes. We review the theory of g modes, including theoretical estimation of the
g-mode frequencies, amplitudes and damping rates. Then we go on to discuss the
techniques that have been used to try to detect g modes. We review results in
the literature, and finish by looking to the future, and the potential advances
that can be made -- from both data and data-analysis perspectives -- to give
unambiguous detections of individual g modes. The review ends by concluding
that, at the time of writing, there is indeed a consensus amongst the authors
that there is currently no undisputed detection of solar g modes.Comment: 71 pages, 18 figures, accepted by Astronomy and Astrophysics Revie
- …