290 research outputs found

    Strategies For Improving Electrospinability Of Polysulfone

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    The overall objective of this study is the fabrication of defect-free electrospun mats of polysulfone (PSU) for applications as a porous support for proton exchange membranes. Electrospinning of PSU from dimethylformamide (DMF) solution generated mats free of cast formation and over-wetting, but unspun droplets were frequently observed in the mats because the electrospun jet was unstable. A stable jet and a large reduction of beads in the electrospun mats were obtained with a mixture of 20 vol.% acetone in DMF. Subsequent optomization of the flow rate to 1.5 mL/h and the applied voltage to 14 kV generated electrospun mats free of any beads based on SEM analysis

    Justification of the period of training ore mining

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    Приведены результаты и получены зависимости величины потери информации о среднеквадратическом отклонении содержания полезного компонента в рудопотоке от периода опробования забоев, которые могут быть использованы для обоснования оптимального периода опробования для функционирования общекарьерной технологии управления качеством рудопотоков. Наведено результати і отримано залежності величини втрати інформації про середньоквадратичне відхилення вмісту корисного компонента в рудопотоці від періоду опробування забоїв, які можуть бути використані для обґрунтування оптимального періоду випробування для функціонування загальнокар’єрної технології управління якістю рудопотоків

    Дослідження впливу якості фінального рудопотоку на прогнозний прибуток гірничо-збагачувального комбінату

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    Встановлення впливу якісних характеристик фінального рудного вантажопотоку залізорудного ГЗК на показники прогнозного прибутку комбінату: проблема зниження загальної собівартості виробництва та за рахунок цього підвищення прибутку гірничо-збагачувальних комбінатів України може бути вирішеною шляхом мінімізації витрат на збагачення сировини шляхом формування фінальних рудопотоків з чітко заданими показниками якості, що забезпечують оптимальні режими роботи збагачувального комплексу.Установление влияния качественных характеристик финального рудного грузопотока железорудного ГОКа на показатели прогнозной прибыли комбината: проблема снижения себестоимости производства и за счет этого повышения прибыли горно-обогатительных комбинатов Украины может быть решена путем минимизации затрат на обогащение путем формирования финальных рудопотоков с четко заданными показателям качества, обеспечивающими оптимальные режимы работы обогатительного комплекса.The research is to determine the impact of the qualitative characteristics of final ore-flow of the iron-ore mining processing plant on the indicators of the forecast profit of the plant. This is due to the fact that decrease in the total cost of production and the resulting increase in profits of the iron-ore mining processing plants can be achieved by minimizing the costs of enrichment by means of forming the final ore-flow with the specified quality indicators that ensure the optimal operating conditions for the iron ore mining processing plant

    Removal of bisphenol, using antimony nanoparticle multi-walled carbon nanotubes composite from aqueous solutions

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    This study focuses on preparing Antimony Nanoparticle Multi-walled Carbon (ANMWC) composite as an effective adsorbent and then the effect of produced composite in BPA removal from aqueous solutions was studied. ANMWC were prepared using chemical method and characterized with X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR) and Brunauer-Emmett-Teller (BET). Moreover, the removal efficiency of prepared AMWCNT and Nanoparticle Multi-walled Carbon (MWCNT) in removal of Bisphenol A was investigated. Results revealed that the BPA removal efficiency by AMWCNT increased from 80 to 93 with the increase of contact time 5 to 60 min. The maximum removal efficiency for the both adsorbents was seen at pH 7, which was 85 for MWCNT and 95 for ANMWC composite. According to the results obtained, pHzpc for both adsorbents was 7. Results showed that the adsorption process followed the pseudo-first order model with a high correlation value and BPA adsorption on MWCNT followed the Langmuir isotherm model

    What Is the Additive Value of Nutritional Deficiency to Va-Fi in the Risk Assessment For Heart Failure Patients?

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    OBJECTIVES: to assess the impact of adding the Prognostic Nutritional Index (PNI) to the U.S. Veterans Health Administration frailty index (VA-FI) for the prediction of time-to-death and other clinical outcomes in Veterans hospitalized with Heart Failure. METHODS: A retrospective cohort study of veterans hospitalized for heart failure (HF) from October 2015 to October 2018. Veterans ≥50 years with albumin and lymphocyte counts, needed to calculate the PNI, in the year prior to hospitalization were included. We defined malnutrition as PNI ≤43.6, based on the Youden index. VA-FI was calculated from the year prior to the hospitalization and identified three groups: robust (≤0.1), prefrail (0.1-0.2), and frail (\u3e0.2). Malnutrition was added to the VA-FI (VA-FI-Nutrition) as a 32 RESULTS: We identified 37,601 Veterans hospitalized for HF (mean age: 73.4 ± 10.3 years, BMI: 31.3 ± 7.4 kg/m CONCLUSION: Adding PNI to VA-FI provides a more accurate and comprehensive assessment among Veterans hospitalized for HF. Clinicians should consider adding a specific nutrition algorithm to automated frailty tools to improve the validity of risk prediction in patients hospitalized with HF

    Mucosa-associated invariant T cells link intestinal immunity with antibacterial immune defects in alcoholic liver disease

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    Background/aims: Intestinal permeability with systemic distribution of bacterial products are central in the immunopathogenesis of alcoholic liver disease (ALD), yet links with intestinal immunity remain elusive. Mucosa-associated invariant T cells (MAIT) are found in liver, blood and intestinal mucosa and are a key component of antibacterial host defences. Their role in ALD is unknown. Methods/design: We analysed frequency, phenotype, transcriptional regulation and function of blood MAIT cells in severe alcoholic hepatitis (SAH), alcohol-related cirrhosis (ARC) and healthy controls (HC). We also examined direct impact of ethanol, bacterial products from faecal extracts and antigenic hyperstimulation on MAIT cell functionality. Presence of MAIT cells in colon and liver was assessed by quantitative PCR and immunohistochemistry/gene expression respectively. Results: In ARC and SAH, blood MAIT cells were dramatically depleted, hyperactivated and displayed defective antibacterial cytokine/cytotoxic responses. These correlated with suppression of lineage-specific transcription factors and hyperexpression of homing receptors in the liver with intrahepatic preservation of MAIT cells in ALD. These alterations were stronger in SAH, where surrogate markers of bacterial infection and microbial translocation were higher than ARC. Ethanol exposure in vitro, in vivo alcohol withdrawal and treatment with Escherichia coli had no effect on MAIT cell frequencies, whereas exposure to faecal bacteria/antigens induced functional impairments comparable with blood MAIT cells from ALD and significant MAIT cell depletion, which was not observed in other T cell compartments. Conclusions: In ALD, the antibacterial potency of MAIT cells is compromised as a consequence of contact with microbial products and microbiota, suggesting that the ‘leaky’ gut observed in ALD drives MAIT cell dysfunction and susceptibility to infection in these patients

    ИССЛЕДОВАНИЕ ВЛИЯНИЯ ПЕРИОДА ОПРОБОВАНИЯ ЗАБОЕВ ЖЕЛЕЗОРУДНОГО КАРЬЕРА НА ПРИБЫЛЬ ГОРНО-ОБОГАТИТЕЛЬНОГО КОМБИНАТА

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    Определена взаимосвязь между периодом опробования забоев ка- рьера и показателями относительной потери информации о содер- жании поленого компонента в рудопотоке и прогнозной прибыли ГОКа. Рассмотрена математическая модель процесса опробования забоев карьера при формировании общекарьерного рудопотока. На примере ПАО «Полтавский ГОК» с применением математических методов дана оценка величины возможного снижения прибыли го- рно-обогатительного комбината вследствие потери информации о содержании полезного компонента как функции от дискретности опробования

    Measurement of the Spin-Dependence of the pbar-p Interaction at the AD-Ring

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    We propose to use an internal polarized hydrogen storage cell gas target in the AD ring to determine for the first time the two total spin-dependent pbar-p cross sections sigma_1 and sigma_2 at antiproton beam energies in the range from 50 to 450 MeV. The data obtained are of interest by themselves for the general theory of pbar-p interactions since they will provide a first experimental constraint of the spin-spin dependence of the nucleon-antinucleon potential in the energy range of interest. In addition, measurements of the polarization buildup of stored antiprotons are required to define the optimum parameters of a future, dedicated Antiproton Polarizer Ring (APR), intended to feed a double-polarized asymmetric pbar-p collider with polarized antiprotons. Such a machine has recently been proposed by the PAX collaboration for the new Facility for Antiproton and Ion Research (FAIR) at GSI in Darmstadt, Germany. The availability of an intense stored beam of polarized antiprotons will provide access to a wealth of single- and double-spin observables, thereby opening a new window on QCD spin physics.Comment: 51 pages, 23 figures, proposal submitted to the SPS committee of CER

    Synthesis of Indium Nanowires by Galvanic Displacement and Their Optical Properties

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    <p>Abstract</p> <p>Single crystalline indium nanowires were prepared on Zn substrate which had been treated in concentrated sulphuric acid by galvanic displacement in the 0.002 mol L<sup>&#8722;1</sup>In<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub>-0.002 mol L<sup>&#8722;1</sup>SeO<sub>2</sub>-0.02 mol L<sup>&#8722;1</sup>SDS-0.01 mol L<sup>&#8722;1</sup>citric acid aqueous solution. The typical diameter of indium nanowires is 30 nm and most of the nanowires are over 30 &#956;m in length. XRD, HRTEM, SAED and structural simulation clearly demonstrate that indium nanowires are single-crystalline with the tetragonal structure, the growth direction of the nanowires is along [100] facet. The UV-Vis absorption spectra showed that indium nanowires display typical transverse resonance of SPR properties. The surfactant (SDS) and the pretreatment of Zn substrate play an important role in the growth process. The mechanism of indium nanowires growth is the synergic effect of treated Zn substrate (hard template) and SDS (soft template).</p

    Soluble Fas might serve as a diagnostic tool for gastric adenocarcinoma

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    <p>Abstract</p> <p>Background</p> <p>Fas (Apo-1/CD95) and its specific ligand (FasL) are key elements in apoptosis. They have been studied in different malignancies but there are few published studies about the soluble forms of these markers (i.e. sFas/sFasL) in gastric cancer. We have compared the serum levels of sFas/sFasL in gastric adenocarcinoma patients and cases with pre-neoplastic lesions as potential markers for early diagnosis, and investigated their relation with clinicopathological characteristics.</p> <p>Methods</p> <p>Fifty-nine newly-diagnosed cases of gastric adenocarcinoma who had undergone gastrectomy, along with 62 endoscopically- and histologically-confirmed non-cancer individuals were enrolled in this study. sFas/sFasL serum levels were detected by Enzyme Linked Immunosurbent Assay.</p> <p>Results</p> <p>Mean serum sFas level was significantly higher in gastric cancer patients than in control group (305.97 ± 63.71 (pg/ml) vs. 92.98 ± 4.95 (pg/ml), P < 0.001); while the mean serum level of sFasL was lower in patients with gastric adenocarcinoma (0.138 ± 0.04 (pg/ml) vs. 0.150 ± 0.02 (pg/ml), P < 0.001). Mean serum levels of sFas/sFasL were significantly different in both intestinal/diffuse and cardiac/non-cardiac subtypes when compared to the control group (P < 0.001). There was an increase in the serum level of sFas from the first steps of pre-neoplastic lesions to gastric adenocarcinoma (P < 0.001). Patients who had no lymph node involvement (<it>N<sub>0</sub></it>) showed significantly higher serum levels of sFas compared to others (P = 0.044).</p> <p>Conclusions</p> <p>Production of sFas may play a critical role in the carcinogenesis of intestinal-type gastric cancer. sFas serum level may serve as a non-invasive tool for early diagnosis of gastric cancer.</p
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